SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 5 GLY A 106
LEU A  12
THR A   8
VAL A 346
 None
 0.94A 1ekjF-2f7vA:
undetectable
1ekjG-2f7vA:
undetectable		 1ekjF-2f7vA:
20.92
1ekjG-2f7vA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 5 HIS A 340
GLU A 344
ALA A 342
SER A  79
 None
 1.03A 1errA-2f7vA:
undetectable
1errB-2f7vA:
undetectable		 1errA-2f7vA:
19.53
1errB-2f7vA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		3 / 3 GLN A  40
ILE A 104
HIS A  72
 None
CO  A5367 ( 4.7A)
CO  A5367 (-3.4A)
 0.57A 1fm9A-2f7vA:
undetectable		 1fm9A-2f7vA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		3 / 3 GLN A  40
ILE A 104
HIS A  72
 None
CO  A5367 ( 4.7A)
CO  A5367 (-3.4A)
 0.56A 1k74A-2f7vA:
undetectable		 1k74A-2f7vA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 5 GLU A  10
THR A   2
LEU A   4
LEU A   5
 None
 0.95A 1u18B-2f7vA:
undetectable		 1u18B-2f7vA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		5 / 10 TYR A  67
ALA A 123
PHE A  69
LEU A 111
GLY A 118
 None
 1.21A 1uhoA-2f7vA:
undetectable		 1uhoA-2f7vA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 8 GLU A 155
HIS A  72
ASP A 103
GLU A 131
 CO  A5367 (-2.1A)
CO  A5367 (-3.4A)
CO  A5367 (-2.2A)
CO  A5367 ( 4.0A)
 0.90A 1v7zA-2f7vA:
4.0		 1v7zA-2f7vA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 8 GLU A 155
HIS A  72
ASP A 103
GLU A 131
 CO  A5367 (-2.1A)
CO  A5367 (-3.4A)
CO  A5367 (-2.2A)
CO  A5367 ( 4.0A)
 0.90A 1v7zB-2f7vA:
4.0		 1v7zB-2f7vA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 8 GLU A 155
HIS A  72
ASP A 103
GLU A 131
 CO  A5367 (-2.1A)
CO  A5367 (-3.4A)
CO  A5367 (-2.2A)
CO  A5367 ( 4.0A)
 0.91A 1v7zC-2f7vA:
4.0		 1v7zC-2f7vA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 8 GLU A 155
HIS A  72
ASP A 103
GLU A 131
 CO  A5367 (-2.1A)
CO  A5367 (-3.4A)
CO  A5367 (-2.2A)
CO  A5367 ( 4.0A)
 0.90A 1v7zD-2f7vA:
3.9		 1v7zD-2f7vA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 8 GLU A 155
HIS A  72
ASP A 103
GLU A 131
 CO  A5367 (-2.1A)
CO  A5367 (-3.4A)
CO  A5367 (-2.2A)
CO  A5367 ( 4.0A)
 0.90A 1v7zE-2f7vA:
3.9		 1v7zE-2f7vA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 8 GLU A 155
HIS A  72
ASP A 103
GLU A 131
 CO  A5367 (-2.1A)
CO  A5367 (-3.4A)
CO  A5367 (-2.2A)
CO  A5367 ( 4.0A)
 0.90A 1v7zF-2f7vA:
4.0		 1v7zF-2f7vA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 7 ALA A 203
GLY A 201
GLY A 200
PHE A 223
 None
 0.72A 2c49B-2f7vA:
undetectable		 2c49B-2f7vA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 8 GLU A 155
HIS A  72
ASP A 103
GLU A 131
 CO  A5367 (-2.1A)
CO  A5367 (-3.4A)
CO  A5367 (-2.2A)
CO  A5367 ( 4.0A)
 0.93A 3a6jA-2f7vA:
4.0		 3a6jA-2f7vA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 7 GLU A 155
HIS A  72
ASP A 103
GLU A 131
 CO  A5367 (-2.1A)
CO  A5367 (-3.4A)
CO  A5367 (-2.2A)
CO  A5367 ( 4.0A)
 0.93A 3a6jB-2f7vA:
3.9		 3a6jB-2f7vA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 8 GLU A 155
HIS A  72
ASP A 103
GLU A 131
 CO  A5367 (-2.1A)
CO  A5367 (-3.4A)
CO  A5367 (-2.2A)
CO  A5367 ( 4.0A)
 0.93A 3a6jC-2f7vA:
4.0		 3a6jC-2f7vA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 8 GLU A 155
HIS A  72
ASP A 103
GLU A 131
 CO  A5367 (-2.1A)
CO  A5367 (-3.4A)
CO  A5367 (-2.2A)
CO  A5367 ( 4.0A)
 0.94A 3a6jE-2f7vA:
4.0		 3a6jE-2f7vA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 8 GLU A 155
HIS A  72
ASP A 103
GLU A 131
 CO  A5367 (-2.1A)
CO  A5367 (-3.4A)
CO  A5367 (-2.2A)
CO  A5367 ( 4.0A)
 0.93A 3a6jF-2f7vA:
4.1		 3a6jF-2f7vA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 8 ILE A  33
PHE A  34
GLU A 131
THR A  75
 None
None
CO  A5367 ( 4.0A)
None
 0.87A 3ua5A-2f7vA:
undetectable		 3ua5A-2f7vA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 6 HIS A  51
SER A  57
ASP A 103
ASP A 129
 None
None
CO  A5367 (-2.2A)
None
 1.26A 4blvA-2f7vA:
undetectable		 4blvA-2f7vA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		5 / 9 GLY A 100
ALA A 109
GLY A 106
VAL A  16
VAL A 346
 None
 1.43A 4c5lB-2f7vA:
undetectable		 4c5lB-2f7vA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		5 / 10 GLY A 100
ALA A 109
GLY A 106
VAL A  16
VAL A 346
 None
 1.41A 4c5lC-2f7vA:
undetectable		 4c5lC-2f7vA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		5 / 10 GLY A 100
ALA A 109
GLY A 106
VAL A  16
VAL A 346
 None
 1.39A 4c5lD-2f7vA:
undetectable		 4c5lD-2f7vA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		5 / 10 GLY A 100
ALA A 109
GLY A 106
VAL A  16
VAL A 346
 None
 1.42A 4c5nD-2f7vA:
undetectable		 4c5nD-2f7vA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EBK_B_TOYB302_1
(AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		5 / 9 ASP A 103
ALA A 154
GLU A 130
ASP A  74
GLU A 131
 CO  A5367 (-2.2A)
None
CO  A5367 (-3.8A)
None
CO  A5367 ( 4.0A)
 1.39A 4ebkA-2f7vA:
0.0
4ebkB-2f7vA:
0.0		 4ebkA-2f7vA:
24.67
4ebkB-2f7vA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		5 / 10 LEU A  37
ILE A  33
GLY A  32
GLY A  31
PHE A 126
 None
 1.03A 4fakA-2f7vA:
undetectable		 4fakA-2f7vA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		5 / 12 GLY A 118
VAL A 355
PHE A 124
ILE A 362
PHE A  44
 None
 1.27A 4fglA-2f7vA:
2.6
4fglB-2f7vA:
2.5		 4fglA-2f7vA:
21.45
4fglB-2f7vA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		6 / 11 HIS A  72
ASP A 103
GLU A 130
GLU A 131
GLU A 155
HIS A 340
 CO  A5367 (-3.4A)
CO  A5367 (-2.2A)
CO  A5367 (-3.8A)
CO  A5367 ( 4.0A)
CO  A5367 (-2.1A)
None
 0.33A 4pqaA-2f7vA:
32.6		 4pqaA-2f7vA:
27.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 5 LEU A 111
TYR A 354
ALA A 154
ILE A 104
 None
None
None
CO  A5367 ( 4.7A)
 1.03A 4y03B-2f7vA:
undetectable		 4y03B-2f7vA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		5 / 10 ASP A 103
VAL A 346
LEU A  12
THR A   8
ALA A 109
 CO  A5367 (-2.2A)
None
None
None
None
 1.18A 4yhaB-2f7vA:
undetectable		 4yhaB-2f7vA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		5 / 12 GLN A 338
ILE A  97
VAL A  96
VAL A  71
PRO A 156
 None
 1.18A 5ergB-2f7vA:
undetectable		 5ergB-2f7vA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		3 / 3 GLY A 264
VAL A 171
MET A 173
 None
 0.64A 5ycpA-2f7vA:
undetectable		 5ycpA-2f7vA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		3 / 3 GLN A  40
ILE A 104
HIS A  72
 None
CO  A5367 ( 4.7A)
CO  A5367 (-3.4A)
 0.56A 5z12B-2f7vA:
undetectable		 5z12B-2f7vA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_GLYA607_0
(UNCHARACTERIZED
PROTEIN)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		4 / 4 GLU A 344
ASP A 343
ARG A  90
TRP A  82
 None
 1.44A 6mn8A-2f7vA:
0.0		 6mn8A-2f7vA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 2f7v AECTYLCITRULLINE
DEACETYLASE
(Xanthomonas
campestris) 		5 / 12 VAL A 330
VAL A 153
PHE A 314
HIS A 340
ILE A 168
 None
 1.43A 6mxtA-2f7vA:
undetectable		 6mxtA-2f7vA:
22.27