SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f86'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 2f86 HYPOTHETICAL PROTEIN
K11E8.1D
(Caenorhabditis
elegans) 		4 / 5 VAL B 356
THR B 357
VAL B 429
TRP B 455
 None
 0.62A 2p2fA-2f86B:
undetectable		 2p2fA-2f86B:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2f86 HYPOTHETICAL PROTEIN
K11E8.1D
(Caenorhabditis
elegans) 		3 / 3 ILE B 353
VAL B 429
PRO B 417
 None
 0.73A 5uunA-2f86B:
undetectable		 5uunA-2f86B:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 2f86 HYPOTHETICAL PROTEIN
K11E8.1D
(Caenorhabditis
elegans) 		4 / 6 TYR B 431
VAL B 419
VAL B 354
THR B 357
 None
 1.29A 6f32B-2f86B:
undetectable		 6f32B-2f86B:
15.95