SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 2f9f FIRST MANNOSYL
TRANSFERASE (WBAZ-1)
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  92
LEU A  32
LEU A  30
MET A 146
ILE A 143
 None
 1.19A 1g50B-2f9fA:
undetectable		 1g50B-2f9fA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 2f9f FIRST MANNOSYL
TRANSFERASE (WBAZ-1)
(Archaeoglobus
fulgidus) 		5 / 11 LEU A  92
LEU A  32
LEU A  30
MET A 146
ILE A 143
 None
 1.19A 1g50C-2f9fA:
undetectable		 1g50C-2f9fA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 2f9f FIRST MANNOSYL
TRANSFERASE (WBAZ-1)
(Archaeoglobus
fulgidus) 		4 / 8 VAL A 117
GLU A  98
ALA A  95
PRO A 104
 None
 1.00A 2v32A-2f9fA:
undetectable
2v32B-2f9fA:
undetectable		 2v32A-2f9fA:
26.85
2v32B-2f9fA:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 2f9f FIRST MANNOSYL
TRANSFERASE (WBAZ-1)
(Archaeoglobus
fulgidus) 		4 / 8 PRO A 104
VAL A 117
GLU A  98
ALA A  95
 None
 0.95A 2v32A-2f9fA:
undetectable
2v32B-2f9fA:
undetectable		 2v32A-2f9fA:
26.85
2v32B-2f9fA:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 2f9f FIRST MANNOSYL
TRANSFERASE (WBAZ-1)
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  30
THR A  94
LEU A  43
ILE A  45
SER A  18
 None
 1.29A 2ydoA-2f9fA:
0.0		 2ydoA-2f9fA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 2f9f FIRST MANNOSYL
TRANSFERASE (WBAZ-1)
(Archaeoglobus
fulgidus) 		4 / 7 LEU A  30
SER A  18
THR A 103
VAL A 117
 None
 1.00A 4wnvD-2f9fA:
undetectable		 4wnvD-2f9fA:
15.87