SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 2f9h PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		4 / 8 PRO A 111
THR A  63
GLY A  61
LEU A 105
 None
 0.74A 1h4oG-2f9hA:
undetectable		 1h4oG-2f9hA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2f9h PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		3 / 3 THR A  85
GLU A  21
HIS A  38
 None
 0.54A 1xwfA-2f9hA:
undetectable		 1xwfA-2f9hA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2f9h PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		3 / 3 THR A  85
GLU A  21
HIS A  38
 None
 0.52A 1xwfB-2f9hA:
undetectable		 1xwfB-2f9hA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2f9h PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		3 / 3 THR A  85
GLU A  21
HIS A  38
 None
 0.55A 1xwfC-2f9hA:
undetectable		 1xwfC-2f9hA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2f9h PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		3 / 3 THR A  85
GLU A  21
HIS A  38
 None
 0.54A 1xwfD-2f9hA:
undetectable		 1xwfD-2f9hA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 2f9h PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		5 / 11 MET A   5
ALA A   7
LEU A  78
VAL A  50
ILE A  67
 None
 1.13A 3jw5A-2f9hA:
undetectable		 3jw5A-2f9hA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 2f9h PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		5 / 10 MET A   5
ALA A   7
LEU A  78
VAL A  50
ILE A  67
 None
 1.14A 3jw5B-2f9hA:
undetectable		 3jw5B-2f9hA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 2f9h PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		5 / 11 LEU A 105
THR A 117
ILE A 119
LEU A  26
ILE A 113
 None
 1.08A 3tqbA-2f9hA:
undetectable		 3tqbA-2f9hA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2f9h PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		3 / 3 ALA A  74
ASN A  77
LEU A  78
 None
 0.49A 5i1nC-2f9hA:
undetectable		 5i1nC-2f9hA:
18.37