SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7C_A_HLTA4007_1 (SERUM ALBUMIN)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	4 / 8	LEU A 255 HIS A 258 ASP A 270 LEU A 271	None	0.91A	1e7cA-2f9qA: 3.1	1e7cA-2f9qA: 22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KGL_A_RTLA175_0 (CELLULAR RETINOL-BINDING PROTEIN TYPE I)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	PHE A 247 LEU A 213 ALA A 209 SER A 183 LEU A 255	None	1.01A	1kglA-2f9qA: undetectable	1kglA-2f9qA: 14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N13_H_AG2H7012_1 (PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE ALPHA CHAIN PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE BETA CHAIN)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	4 / 6	ARG A 62 ASP A 405 LEU A 84 GLY A 83	None	0.95A	1n13H-2f9qA: undetectable 1n13K-2f9qA: undetectable	1n13H-2f9qA: 12.68 1n13K-2f9qA: 7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NW3_A_SAMA500_0 (HISTONE METHYLTRANSFERASE DOT1L)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	GLU A 406 ASP A 67 GLY A 83 ALA A 432 LEU A 91	None	1.21A	1nw3A-2f9qA: undetectable	1nw3A-2f9qA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q6I_B_FK5B401_1 (FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 10	ASP A 292 ARG A 259 LEU A 276 VAL A 298 ILE A 297	None	1.17A	1q6iB-2f9qA: undetectable	1q6iB-2f9qA: 19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA3_C_STRC3001_1 (MINERALOCORTICOID RECEPTOR)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	LEU A 254 LEU A 251 LEU A 248 GLN A 244 LEU A 206	None	1.03A	1ya3C-2f9qA: undetectable	1ya3C-2f9qA: 19.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	4 / 7	LEU A 302 PHE A 303 GLY A 306 THR A 310	HEM A 600 ( 4.5A) None HEM A 600 (-3.1A) HEM A 600 (-4.0A)	0.58A	2bdmA-2f9qA: 37.0	2bdmA-2f9qA: 45.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	4 / 7	SER A 135 LEU A 302 GLY A 306 THR A 309	None HEM A 600 ( 4.5A) HEM A 600 (-3.1A) HEM A 600 (-3.5A)	1.12A	2bdmA-2f9qA: 37.0	2bdmA-2f9qA: 45.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BFP_C_H4BC1290_1 (PTERIDINE REDUCTASE 1)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	4 / 8	PHE A 172 LEU A 492 LEU A 178 LEU A 160	None	0.94A	2bfpC-2f9qA: undetectable	2bfpC-2f9qA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FB2_A_SAMA501_0 (MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	4 / 8	CYH A 443 GLU A 452 VAL A 370 MET A 374	HEM A 600 (-2.4A) HEM A 600 (-4.5A) HEM A 600 ( 4.9A) None	0.92A	2fb2A-2f9qA: undetectable	2fb2A-2f9qA: 22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_ACTA507_0 (CHORISMATE SYNTHASE)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	3 / 3	LEU A 144 ASN A 141 ARG A 140	None	0.91A	2qhfA-2f9qA: undetectable	2qhfA-2f9qA: 25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QMZ_B_LDPB502_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	4 / 5	PHE A 420 PHE A 433 TRP A 409 GLY A 367	None	1.25A	2qmzA-2f9qA: undetectable 2qmzB-2f9qA: undetectable	2qmzA-2f9qA: 19.42 2qmzB-2f9qA: 19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_K_ASDK1224_1 (GLUTATHIONE S-TRANSFERASE A3)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 6	PHE A 464 LEU A 177 PRO A 174 LEU A 492 ALA A 494	None	1.48A	2vcvK-2f9qA: undetectable	2vcvK-2f9qA: 20.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3E4E_A_4PZA501_1 (CYTOCHROME P450 2E1)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	3 / 3	ALA A 305 THR A 309 CYH A 443	HEM A 600 (-3.6A) HEM A 600 (-3.5A) HEM A 600 (-2.4A)	0.42A	3e4eA-2f9qA: 44.3	3e4eA-2f9qA: 41.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3E4E_B_4PZB501_1 (CYTOCHROME P450 2E1)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	3 / 3	ALA A 305 THR A 309 CYH A 443	HEM A 600 (-3.6A) HEM A 600 (-3.5A) HEM A 600 (-2.4A)	0.31A	3e4eB-2f9qA: 44.2	3e4eB-2f9qA: 41.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA150_0 (ILEAL BILE ACID-BINDING PROTEIN)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	THR A 154 VAL A 153 VAL A 338 ILE A 339 THR A 356	None	1.39A	3elzA-2f9qA: undetectable	3elzA-2f9qA: 13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_B_CHDB150_0 (ILEAL BILE ACID-BINDING PROTEIN)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 11	THR A 154 VAL A 153 VAL A 338 ILE A 339 THR A 356	None	1.47A	3elzB-2f9qA: undetectable	3elzB-2f9qA: 13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RUK_A_AERA601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	ASP A 301 ALA A 305 THR A 309 VAL A 370 CYH A 443	None HEM A 600 (-3.6A) HEM A 600 (-3.5A) HEM A 600 ( 4.9A) HEM A 600 (-2.4A)	0.93A	3rukA-2f9qA: 43.6	3rukA-2f9qA: 29.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_A_RTZA1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	8 / 12	LEU A 110 PHE A 112 PHE A 120 LEU A 121 GLY A 212 GLN A 244 ASP A 301 SER A 304	None None HEM A 600 (-4.6A) None None None None None	1.18A	3tbgA-2f9qA: 54.3	3tbgA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_A_RTZA1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	8 / 12	LEU A 110 PHE A 112 PHE A 120 LEU A 121 GLY A 212 PHE A 247 ASP A 301 SER A 304	None None HEM A 600 (-4.6A) None None None None None	0.80A	3tbgA-2f9qA: 54.3	3tbgA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_A_RTZA1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	LEU A 110 PHE A 112 PHE A 120 LEU A 121 PHE A 483	None None HEM A 600 (-4.6A) None None	0.98A	3tbgA-2f9qA: 54.3	3tbgA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_A_RTZA1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	LEU A 248 GLY A 212 GLN A 244 ASP A 301 SER A 304	None	1.34A	3tbgA-2f9qA: 54.3	3tbgA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_A_RTZA1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 12	PHE A 120 LEU A 121 GLY A 212 LEU A 213 GLU A 216 GLN A 244	HEM A 600 (-4.6A) None None None None None	1.32A	3tbgA-2f9qA: 54.3	3tbgA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_A_RTZA2_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 11	THR A 54 VAL A 78 LEU A 372 THR A 375 PHE A 481	None	0.72A	3tbgA-2f9qA: 54.3	3tbgA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_B_RTZB1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	8 / 12	LEU A 110 PHE A 112 PHE A 120 LEU A 121 GLY A 212 GLN A 244 ASP A 301 SER A 304	None None HEM A 600 (-4.6A) None None None None None	1.13A	3tbgB-2f9qA: 55.7	3tbgB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_B_RTZB1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	9 / 12	LEU A 110 PHE A 112 PHE A 120 LEU A 121 GLY A 212 PHE A 247 ALA A 300 ASP A 301 SER A 304	None None HEM A 600 (-4.6A) None None None None None None	0.72A	3tbgB-2f9qA: 55.7	3tbgB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_B_RTZB1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 12	PHE A 120 LEU A 121 GLY A 212 GLU A 216 GLN A 244 ASP A 301	HEM A 600 (-4.6A) None None None None None	1.11A	3tbgB-2f9qA: 55.7	3tbgB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_C_RTZC1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	8 / 12	LEU A 110 PHE A 112 PHE A 120 LEU A 121 GLY A 212 GLN A 244 ASP A 301 SER A 304	None None HEM A 600 (-4.6A) None None None None None	1.18A	3tbgC-2f9qA: 54.4	3tbgC-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_C_RTZC1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	8 / 12	LEU A 110 PHE A 112 PHE A 120 LEU A 121 GLY A 212 PHE A 247 ASP A 301 SER A 304	None None HEM A 600 (-4.6A) None None None None None	0.81A	3tbgC-2f9qA: 54.4	3tbgC-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_C_RTZC1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	LEU A 248 GLY A 212 GLN A 244 ASP A 301 SER A 304	None	1.31A	3tbgC-2f9qA: 54.4	3tbgC-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_C_RTZC1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	LEU A 248 GLY A 212 LEU A 213 GLU A 216 GLN A 244	None	1.35A	3tbgC-2f9qA: 54.4	3tbgC-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_C_RTZC1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	PHE A 120 LEU A 121 GLY A 212 GLU A 216 GLN A 244	HEM A 600 (-4.6A) None None None None	1.18A	3tbgC-2f9qA: 54.4	3tbgC-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_C_RTZC2_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 10	THR A 54 VAL A 78 LEU A 372 THR A 375 PHE A 481	None	0.73A	3tbgC-2f9qA: 54.4	3tbgC-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_D_RTZD1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	8 / 12	LEU A 110 PHE A 112 PHE A 120 LEU A 121 GLY A 212 GLN A 244 ASP A 301 SER A 304	None None HEM A 600 (-4.6A) None None None None None	1.16A	3tbgD-2f9qA: 55.7	3tbgD-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_D_RTZD1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	9 / 12	LEU A 110 PHE A 112 PHE A 120 LEU A 121 GLY A 212 PHE A 247 ALA A 300 ASP A 301 SER A 304	None None HEM A 600 (-4.6A) None None None None None None	0.73A	3tbgD-2f9qA: 55.7	3tbgD-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_D_RTZD1_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 12	PHE A 120 LEU A 121 GLY A 212 GLU A 216 GLN A 244 ASP A 301	HEM A 600 (-4.6A) None None None None None	1.12A	3tbgD-2f9qA: 55.7	3tbgD-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TBG_D_RTZD2_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 9	PHE A 58 VAL A 78 LEU A 372 THR A 375 ILE A 396	None	0.45A	3tbgD-2f9qA: 55.7	3tbgD-2f9qA: 99.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DM8_B_REAB1501_1 (RETINOIC ACID RECEPTOR BETA)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	ALA A 90 LEU A 395 ILE A 396 GLY A 373 LEU A 434	None None None HEM A 600 ( 4.2A) None	1.08A	4dm8B-2f9qA: undetectable	4dm8B-2f9qA: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 8	PHE A 420 ILE A 360 PHE A 433 TRP A 409 GLY A 367	None	1.22A	4fgjA-2f9qA: undetectable 4fgjB-2f9qA: undetectable	4fgjA-2f9qA: 19.63 4fgjB-2f9qA: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_C_RTLC201_0 (RETINOL-BINDING PROTEIN 2)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	PHE A 436 ALA A 449 GLN A 364 VAL A 485 LEU A 403	HEM A 600 (-4.4A) HEM A 600 ( 3.8A) HEM A 600 (-4.5A) None None	1.18A	4qzuC-2f9qA: undetectable	4qzuC-2f9qA: 13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RKU_A_PQNA5001_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 PHOTOSYSTEM I REACTION CENTER SUBUNIT IX)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	4 / 8	PHE A 195 ARG A 204 LEU A 205 PHE A 134	None	1.01A	4rkuA-2f9qA: 0.6 4rkuJ-2f9qA: undetectable	4rkuA-2f9qA: 22.12 4rkuJ-2f9qA: 7.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_A_QDNA602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 11	LEU A 110 GLY A 212 LEU A 213 PHE A 247 LEU A 248	None	0.98A	4wnuA-2f9qA: 55.2	4wnuA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_A_QDNA602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	7 / 11	LEU A 110 PHE A 120 GLY A 212 PHE A 247 LEU A 248 ALA A 300 SER A 304	None HEM A 600 (-4.6A) None None None None None	0.60A	4wnuA-2f9qA: 55.2	4wnuA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_B_QDNB602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 9	LEU A 110 PHE A 120 GLN A 244 ASP A 301 SER A 304 ALA A 305	None HEM A 600 (-4.6A) None None None HEM A 600 (-3.6A)	1.19A	4wnuB-2f9qA: 55.5	4wnuB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_B_QDNB602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	7 / 9	LEU A 110 PHE A 120 PHE A 247 ALA A 300 ASP A 301 SER A 304 ALA A 305	None HEM A 600 (-4.6A) None None None None HEM A 600 (-3.6A)	0.53A	4wnuB-2f9qA: 55.5	4wnuB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_B_QDNB602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 9	LEU A 248 PHE A 120 GLN A 244 ASP A 301 SER A 304 ALA A 305	None HEM A 600 (-4.6A) None None None HEM A 600 (-3.6A)	1.43A	4wnuB-2f9qA: 55.5	4wnuB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_B_QDNB602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 9	LEU A 248 PHE A 120 GLU A 216 GLN A 244 ALA A 305	None HEM A 600 (-4.6A) None None HEM A 600 (-3.6A)	1.46A	4wnuB-2f9qA: 55.5	4wnuB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_C_QDNC602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 11	LEU A 110 PHE A 120 GLY A 212 GLN A 244 ASP A 301 SER A 304	None HEM A 600 (-4.6A) None None None None	1.24A	4wnuC-2f9qA: 55.2	4wnuC-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_C_QDNC602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	7 / 11	LEU A 110 PHE A 120 GLY A 212 PHE A 247 ALA A 300 ASP A 301 SER A 304	None HEM A 600 (-4.6A) None None None None None	0.61A	4wnuC-2f9qA: 55.2	4wnuC-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_C_QDNC602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 11	LEU A 248 PHE A 120 GLY A 212 GLN A 244 ASP A 301 SER A 304	None HEM A 600 (-4.6A) None None None None	1.47A	4wnuC-2f9qA: 55.2	4wnuC-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_D_QDND602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 10	PHE A 120 GLY A 212 GLN A 244 ASP A 301 ALA A 305	HEM A 600 (-4.6A) None None None HEM A 600 (-3.6A)	1.05A	4wnuD-2f9qA: 55.5	4wnuD-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_D_QDND602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 10	PHE A 120 GLY A 212 GLU A 216 GLN A 244 ALA A 305	HEM A 600 (-4.6A) None None None HEM A 600 (-3.6A)	1.27A	4wnuD-2f9qA: 55.5	4wnuD-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_D_QDND602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 10	PHE A 120 GLY A 212 GLU A 216 LEU A 251 ALA A 305	HEM A 600 (-4.6A) None None None HEM A 600 (-3.6A)	1.30A	4wnuD-2f9qA: 55.5	4wnuD-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNU_D_QDND602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	8 / 10	PHE A 120 GLY A 212 PHE A 247 LEU A 248 ALA A 300 ASP A 301 SER A 304 ALA A 305	HEM A 600 (-4.6A) None None None None None None HEM A 600 (-3.6A)	0.53A	4wnuD-2f9qA: 55.5	4wnuD-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNV_A_QI9A602_0 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 9	LEU A 121 SER A 304 THR A 309 PHE A 483 LEU A 484	None None HEM A 600 (-3.5A) None None	1.48A	4wnvA-2f9qA: 54.4	4wnvA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNV_A_QI9A602_0 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 9	PHE A 120 LEU A 121 GLU A 216 SER A 304 THR A 309	HEM A 600 (-4.6A) None None None HEM A 600 (-3.5A)	1.02A	4wnvA-2f9qA: 54.4	4wnvA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNV_A_QI9A602_0 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 9	PHE A 120 LEU A 121 SER A 304 THR A 309 VAL A 370 LEU A 484	HEM A 600 (-4.6A) None None HEM A 600 (-3.5A) HEM A 600 ( 4.9A) None	0.66A	4wnvA-2f9qA: 54.4	4wnvA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNV_B_QI9B602_0 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 9	PHE A 120 LEU A 121 GLU A 216 SER A 304 THR A 309	HEM A 600 (-4.6A) None None None HEM A 600 (-3.5A)	1.06A	4wnvB-2f9qA: 55.7	4wnvB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNV_B_QI9B602_0 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 9	PHE A 120 LEU A 121 SER A 304 THR A 309 VAL A 370	HEM A 600 (-4.6A) None None HEM A 600 (-3.5A) HEM A 600 ( 4.9A)	0.58A	4wnvB-2f9qA: 55.7	4wnvB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNV_C_QI9C602_0 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 9	LEU A 121 ASP A 301 SER A 304 THR A 309 PHE A 483	None None None HEM A 600 (-3.5A) None	1.22A	4wnvC-2f9qA: 55.1	4wnvC-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNV_C_QI9C602_0 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 9	PHE A 120 LEU A 121 ASP A 301 SER A 304 THR A 309 VAL A 370	HEM A 600 (-4.6A) None None None HEM A 600 (-3.5A) HEM A 600 ( 4.9A)	0.60A	4wnvC-2f9qA: 55.1	4wnvC-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNV_D_QI9D602_0 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 7	PHE A 120 LEU A 121 GLU A 216 SER A 304 THR A 309	HEM A 600 (-4.6A) None None None HEM A 600 (-3.5A)	1.10A	4wnvD-2f9qA: 55.5	4wnvD-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNW_A_RTZA602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	7 / 12	PHE A 112 PHE A 120 GLY A 212 ASP A 301 SER A 304 VAL A 308 THR A 309	None HEM A 600 (-4.6A) None None None None HEM A 600 (-3.5A)	0.98A	4wnwA-2f9qA: 50.6	4wnwA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNW_A_RTZA602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	8 / 12	PHE A 112 PHE A 120 GLY A 212 LEU A 213 GLN A 244 ASP A 301 VAL A 308 THR A 309	None HEM A 600 (-4.6A) None None None None None HEM A 600 (-3.5A)	1.30A	4wnwA-2f9qA: 50.6	4wnwA-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNW_B_RTZB602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 12	PHE A 112 PHE A 120 GLY A 212 LEU A 213 ASP A 301 VAL A 308	None HEM A 600 (-4.6A) None None None None	1.10A	4wnwB-2f9qA: 51.5	4wnwB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNW_B_RTZB602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 12	PHE A 112 PHE A 120 GLY A 212 LEU A 213 GLN A 244 VAL A 308	None HEM A 600 (-4.6A) None None None None	1.36A	4wnwB-2f9qA: 51.5	4wnwB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNW_B_RTZB602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	7 / 12	PHE A 112 PHE A 120 LEU A 121 GLY A 212 ALA A 300 ASP A 301 SER A 304	None HEM A 600 (-4.6A) None None None None None	0.73A	4wnwB-2f9qA: 51.5	4wnwB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNW_B_RTZB602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 12	PHE A 112 PHE A 120 LEU A 121 GLY A 212 ASP A 301 VAL A 308	None HEM A 600 (-4.6A) None None None None	0.91A	4wnwB-2f9qA: 51.5	4wnwB-2f9qA: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WNW_B_RTZB602_1 (CYTOCHROME P450 2D6)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	6 / 12	PHE A 112 PHE A 120 LEU A 121 GLY A 212 GLN A 244 VAL A 308	None HEM A 600 (-4.6A) None None None None	1.27A	4wnwB-2f9qA: 51.5	4wnwB-2f9qA: 99.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1I_B_LOCB502_2 (TUBULIN BETA CHAIN)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 12	LEU A 208 ALA A 246 LEU A 248 ALA A 300 ALA A 209	None	1.23A	4x1iB-2f9qA: undetectable	4x1iB-2f9qA: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XR4_B_AG2B511_1 (HOMOSPERMIDINE SYNTHASE)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	3 / 3	VAL A 104 PHE A 120 ARG A 441	None HEM A 600 (-4.6A) HEM A 600 (-3.5A)	0.97A	4xr4B-2f9qA: undetectable	4xr4B-2f9qA: 21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MM4_B_TA1B501_1 (TUBULIN BETA CHAIN)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 10	VAL A 308 LEU A 248 ALA A 305 PHE A 120 LEU A 220	None None HEM A 600 (-3.6A) HEM A 600 (-4.6A) None	1.28A	5mm4B-2f9qA: undetectable	5mm4B-2f9qA: 10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWW_A_ACAA18_2 (SCRFP-TAG,GP41)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	3 / 3	LYS A 404 TRP A 409 SER A 400	None	1.25A	5nwwA-2f9qA: undetectable	5nwwA-2f9qA: 6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BKL_C_EU7C101_0 (MATRIX PROTEIN 2)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 9	ALA A 127 SER A 289 VAL A 119 ALA A 122 VAL A 298	None None HEM A 600 (-4.6A) None None	0.98A	6bklA-2f9qA: undetectable 6bklB-2f9qA: undetectable 6bklC-2f9qA: undetectable 6bklD-2f9qA: undetectable	6bklA-2f9qA: 4.46 6bklB-2f9qA: 4.46 6bklC-2f9qA: 4.46 6bklD-2f9qA: 4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BRD_A_RFPA502_2 (RIFAMPIN MONOOXYGENASE)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	4 / 4	GLN A 332 VAL A 359 ARG A 344 ARG A 497	None	1.40A	6brdA-2f9qA: 0.0	6brdA-2f9qA: 12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6ECE_C_DVAC3010_0 (VLM2 DODECADEPSIPEPTIDE)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	3 / 3	ALA A 274 PHE A 290 GLN A 131	None	0.83A	6eceA-2f9qA: undetectable	6eceA-2f9qA: 23.28

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7C_A_HLTA4007_1","SERUM ALBUMIN","2f9q","CYTOCHROME P450 2D6","Homo sapiens",4,"LEU A 255;HIS A 258;ASP A 270;LEU A 271","None","0.91A","1e7cA-2f9qA:3.1","1e7cA-2f9qA:22.17"],["1KGL_A_RTLA175_0","CELLULAR RETINOL-BINDING PROTEIN TYPE I","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A 247;LEU A 213;ALA A 209;SER A 183;LEU A 255","None","1.01A","1kglA-2f9qA:undetectable","1kglA-2f9qA:14.41"],["1N13_H_AG2H7012_1","PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE ALPHA CHAIN;PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE BETA CHAIN","2f9q","CYTOCHROME P450 2D6","Homo sapiens",4,"ARG A  62;ASP A 405;LEU A  84;GLY A  83","None","0.95A","1n13H-2f9qA:undetectable;1n13K-2f9qA:undetectable","1n13H-2f9qA:12.68;1n13K-2f9qA:7.27"],["1NW3_A_SAMA500_0","HISTONE METHYLTRANSFERASE DOT1L","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"GLU A 406;ASP A  67;GLY A  83;ALA A 432;LEU A  91","None","1.21A","1nw3A-2f9qA:undetectable","1nw3A-2f9qA:21.48"],["1Q6I_B_FK5B401_1","FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"ASP A 292;ARG A 259;LEU A 276;VAL A 298;ILE A 297","None","1.17A","1q6iB-2f9qA:undetectable","1q6iB-2f9qA:19.42"],["1YA3_C_STRC3001_1","MINERALOCORTICOID RECEPTOR","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"LEU A 254;LEU A 251;LEU A 248;GLN A 244;LEU A 206","None","1.03A","1ya3C-2f9qA:undetectable","1ya3C-2f9qA:19.83"],["2BDM_A_TMIA501_1","CYTOCHROME P450 2B4","2f9q","CYTOCHROME P450 2D6","Homo sapiens",4,"LEU A 302;PHE A 303;GLY A 306;THR A 310","HEM A 600 ( 4.5A);None;HEM A 600 (-3.1A);HEM A 600 (-4.0A)","0.58A","2bdmA-2f9qA:37.0","2bdmA-2f9qA:45.66"],["2BDM_A_TMIA501_1","CYTOCHROME P450 2B4","2f9q","CYTOCHROME P450 2D6","Homo sapiens",4,"SER A 135;LEU A 302;GLY A 306;THR A 309","None;HEM A 600 ( 4.5A);HEM A 600 (-3.1A);HEM A 600 (-3.5A)","1.12A","2bdmA-2f9qA:37.0","2bdmA-2f9qA:45.66"],["2BFP_C_H4BC1290_1","PTERIDINE REDUCTASE 1","2f9q","CYTOCHROME P450 2D6","Homo sapiens",4,"PHE A 172;LEU A 492;LEU A 178;LEU A 160","None","0.94A","2bfpC-2f9qA:undetectable","2bfpC-2f9qA:21.99"],["2FB2_A_SAMA501_0","MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A","2f9q","CYTOCHROME P450 2D6","Homo sapiens",4,"CYH A 443;GLU A 452;VAL A 370;MET A 374","HEM A 600 (-2.4A);HEM A 600 (-4.5A);HEM A 600 ( 4.9A);None","0.92A","2fb2A-2f9qA:undetectable","2fb2A-2f9qA:22.90"],["2QHF_A_ACTA507_0","CHORISMATE SYNTHASE","2f9q","CYTOCHROME P450 2D6","Homo sapiens",3,"LEU A 144;ASN A 141;ARG A 140","None","0.91A","2qhfA-2f9qA:undetectable","2qhfA-2f9qA:25.05"],["2QMZ_B_LDPB502_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE;RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE","2f9q","CYTOCHROME P450 2D6","Homo sapiens",4,"PHE A 420;PHE A 433;TRP A 409;GLY A 367","None","1.25A","2qmzA-2f9qA:undetectable;2qmzB-2f9qA:undetectable","2qmzA-2f9qA:19.42;2qmzB-2f9qA:19.42"],["2VCV_K_ASDK1224_1","GLUTATHIONE S-TRANSFERASE A3","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A 464;LEU A 177;PRO A 174;LEU A 492;ALA A 494","None","1.48A","2vcvK-2f9qA:undetectable","2vcvK-2f9qA:20.69"],["3E4E_A_4PZA501_1","CYTOCHROME P450 2E1","2f9q","CYTOCHROME P450 2D6","Homo sapiens",3,"ALA A 305;THR A 309;CYH A 443","HEM A 600 (-3.6A);HEM A 600 (-3.5A);HEM A 600 (-2.4A)","0.42A","3e4eA-2f9qA:44.3","3e4eA-2f9qA:41.77"],["3E4E_B_4PZB501_1","CYTOCHROME P450 2E1","2f9q","CYTOCHROME P450 2D6","Homo sapiens",3,"ALA A 305;THR A 309;CYH A 443","HEM A 600 (-3.6A);HEM A 600 (-3.5A);HEM A 600 (-2.4A)","0.31A","3e4eB-2f9qA:44.2","3e4eB-2f9qA:41.77"],["3ELZ_A_CHDA150_0","ILEAL BILE ACID-BINDING PROTEIN","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"THR A 154;VAL A 153;VAL A 338;ILE A 339;THR A 356","None","1.39A","3elzA-2f9qA:undetectable","3elzA-2f9qA:13.26"],["3ELZ_B_CHDB150_0","ILEAL BILE ACID-BINDING PROTEIN","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"THR A 154;VAL A 153;VAL A 338;ILE A 339;THR A 356","None","1.47A","3elzB-2f9qA:undetectable","3elzB-2f9qA:13.26"],["3RUK_A_AERA601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"ASP A 301;ALA A 305;THR A 309;VAL A 370;CYH A 443","None;HEM A 600 (-3.6A);HEM A 600 (-3.5A);HEM A 600 ( 4.9A);HEM A 600 (-2.4A)","0.93A","3rukA-2f9qA:43.6","3rukA-2f9qA:29.88"],["3TBG_A_RTZA1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",8,"LEU A 110;PHE A 112;PHE A 120;LEU A 121;GLY A 212;GLN A 244;ASP A 301;SER A 304","None;None;HEM A 600 (-4.6A);None;None;None;None;None","1.18A","3tbgA-2f9qA:54.3","3tbgA-2f9qA:99.37"],["3TBG_A_RTZA1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",8,"LEU A 110;PHE A 112;PHE A 120;LEU A 121;GLY A 212;PHE A 247;ASP A 301;SER A 304","None;None;HEM A 600 (-4.6A);None;None;None;None;None","0.80A","3tbgA-2f9qA:54.3","3tbgA-2f9qA:99.37"],["3TBG_A_RTZA1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"LEU A 110;PHE A 112;PHE A 120;LEU A 121;PHE A 483","None;None;HEM A 600 (-4.6A);None;None","0.98A","3tbgA-2f9qA:54.3","3tbgA-2f9qA:99.37"],["3TBG_A_RTZA1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"LEU A 248;GLY A 212;GLN A 244;ASP A 301;SER A 304","None","1.34A","3tbgA-2f9qA:54.3","3tbgA-2f9qA:99.37"],["3TBG_A_RTZA1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"PHE A 120;LEU A 121;GLY A 212;LEU A 213;GLU A 216;GLN A 244","HEM A 600 (-4.6A);None;None;None;None;None","1.32A","3tbgA-2f9qA:54.3","3tbgA-2f9qA:99.37"],["3TBG_A_RTZA2_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"THR A  54;VAL A  78;LEU A 372;THR A 375;PHE A 481","None","0.72A","3tbgA-2f9qA:54.3","3tbgA-2f9qA:99.37"],["3TBG_B_RTZB1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",8,"LEU A 110;PHE A 112;PHE A 120;LEU A 121;GLY A 212;GLN A 244;ASP A 301;SER A 304","None;None;HEM A 600 (-4.6A);None;None;None;None;None","1.13A","3tbgB-2f9qA:55.7","3tbgB-2f9qA:99.37"],["3TBG_B_RTZB1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",9,"LEU A 110;PHE A 112;PHE A 120;LEU A 121;GLY A 212;PHE A 247;ALA A 300;ASP A 301;SER A 304","None;None;HEM A 600 (-4.6A);None;None;None;None;None;None","0.72A","3tbgB-2f9qA:55.7","3tbgB-2f9qA:99.37"],["3TBG_B_RTZB1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"PHE A 120;LEU A 121;GLY A 212;GLU A 216;GLN A 244;ASP A 301","HEM A 600 (-4.6A);None;None;None;None;None","1.11A","3tbgB-2f9qA:55.7","3tbgB-2f9qA:99.37"],["3TBG_C_RTZC1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",8,"LEU A 110;PHE A 112;PHE A 120;LEU A 121;GLY A 212;GLN A 244;ASP A 301;SER A 304","None;None;HEM A 600 (-4.6A);None;None;None;None;None","1.18A","3tbgC-2f9qA:54.4","3tbgC-2f9qA:99.37"],["3TBG_C_RTZC1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",8,"LEU A 110;PHE A 112;PHE A 120;LEU A 121;GLY A 212;PHE A 247;ASP A 301;SER A 304","None;None;HEM A 600 (-4.6A);None;None;None;None;None","0.81A","3tbgC-2f9qA:54.4","3tbgC-2f9qA:99.37"],["3TBG_C_RTZC1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"LEU A 248;GLY A 212;GLN A 244;ASP A 301;SER A 304","None","1.31A","3tbgC-2f9qA:54.4","3tbgC-2f9qA:99.37"],["3TBG_C_RTZC1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"LEU A 248;GLY A 212;LEU A 213;GLU A 216;GLN A 244","None","1.35A","3tbgC-2f9qA:54.4","3tbgC-2f9qA:99.37"],["3TBG_C_RTZC1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A 120;LEU A 121;GLY A 212;GLU A 216;GLN A 244","HEM A 600 (-4.6A);None;None;None;None","1.18A","3tbgC-2f9qA:54.4","3tbgC-2f9qA:99.37"],["3TBG_C_RTZC2_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"THR A  54;VAL A  78;LEU A 372;THR A 375;PHE A 481","None","0.73A","3tbgC-2f9qA:54.4","3tbgC-2f9qA:99.37"],["3TBG_D_RTZD1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",8,"LEU A 110;PHE A 112;PHE A 120;LEU A 121;GLY A 212;GLN A 244;ASP A 301;SER A 304","None;None;HEM A 600 (-4.6A);None;None;None;None;None","1.16A","3tbgD-2f9qA:55.7","3tbgD-2f9qA:99.37"],["3TBG_D_RTZD1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",9,"LEU A 110;PHE A 112;PHE A 120;LEU A 121;GLY A 212;PHE A 247;ALA A 300;ASP A 301;SER A 304","None;None;HEM A 600 (-4.6A);None;None;None;None;None;None","0.73A","3tbgD-2f9qA:55.7","3tbgD-2f9qA:99.37"],["3TBG_D_RTZD1_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"PHE A 120;LEU A 121;GLY A 212;GLU A 216;GLN A 244;ASP A 301","HEM A 600 (-4.6A);None;None;None;None;None","1.12A","3tbgD-2f9qA:55.7","3tbgD-2f9qA:99.37"],["3TBG_D_RTZD2_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A  58;VAL A  78;LEU A 372;THR A 375;ILE A 396","None","0.45A","3tbgD-2f9qA:55.7","3tbgD-2f9qA:99.37"],["4DM8_B_REAB1501_1","RETINOIC ACID RECEPTOR BETA","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"ALA A  90;LEU A 395;ILE A 396;GLY A 373;LEU A 434","None;None;None;HEM A 600 ( 4.2A);None","1.08A","4dm8B-2f9qA:undetectable","4dm8B-2f9qA:19.27"],["4FGJ_A_1PQA304_0","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A 420;ILE A 360;PHE A 433;TRP A 409;GLY A 367","None","1.22A","4fgjA-2f9qA:undetectable;4fgjB-2f9qA:undetectable","4fgjA-2f9qA:19.63;4fgjB-2f9qA:19.63"],["4QZU_C_RTLC201_0","RETINOL-BINDING PROTEIN 2","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A 436;ALA A 449;GLN A 364;VAL A 485;LEU A 403","HEM A 600 (-4.4A);HEM A 600 ( 3.8A);HEM A 600 (-4.5A);None;None","1.18A","4qzuC-2f9qA:undetectable","4qzuC-2f9qA:13.47"],["4RKU_A_PQNA5001_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1;PHOTOSYSTEM I REACTION CENTER SUBUNIT IX","2f9q","CYTOCHROME P450 2D6","Homo sapiens",4,"PHE A 195;ARG A 204;LEU A 205;PHE A 134","None","1.01A","4rkuA-2f9qA:0.6;4rkuJ-2f9qA:undetectable","4rkuA-2f9qA:22.12;4rkuJ-2f9qA:7.18"],["4WNU_A_QDNA602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"LEU A 110;GLY A 212;LEU A 213;PHE A 247;LEU A 248","None","0.98A","4wnuA-2f9qA:55.2","4wnuA-2f9qA:99.37"],["4WNU_A_QDNA602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",7,"LEU A 110;PHE A 120;GLY A 212;PHE A 247;LEU A 248;ALA A 300;SER A 304","None;HEM A 600 (-4.6A);None;None;None;None;None","0.60A","4wnuA-2f9qA:55.2","4wnuA-2f9qA:99.37"],["4WNU_B_QDNB602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"LEU A 110;PHE A 120;GLN A 244;ASP A 301;SER A 304;ALA A 305","None;HEM A 600 (-4.6A);None;None;None;HEM A 600 (-3.6A)","1.19A","4wnuB-2f9qA:55.5","4wnuB-2f9qA:99.37"],["4WNU_B_QDNB602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",7,"LEU A 110;PHE A 120;PHE A 247;ALA A 300;ASP A 301;SER A 304;ALA A 305","None;HEM A 600 (-4.6A);None;None;None;None;HEM A 600 (-3.6A)","0.53A","4wnuB-2f9qA:55.5","4wnuB-2f9qA:99.37"],["4WNU_B_QDNB602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"LEU A 248;PHE A 120;GLN A 244;ASP A 301;SER A 304;ALA A 305","None;HEM A 600 (-4.6A);None;None;None;HEM A 600 (-3.6A)","1.43A","4wnuB-2f9qA:55.5","4wnuB-2f9qA:99.37"],["4WNU_B_QDNB602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"LEU A 248;PHE A 120;GLU A 216;GLN A 244;ALA A 305","None;HEM A 600 (-4.6A);None;None;HEM A 600 (-3.6A)","1.46A","4wnuB-2f9qA:55.5","4wnuB-2f9qA:99.37"],["4WNU_C_QDNC602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"LEU A 110;PHE A 120;GLY A 212;GLN A 244;ASP A 301;SER A 304","None;HEM A 600 (-4.6A);None;None;None;None","1.24A","4wnuC-2f9qA:55.2","4wnuC-2f9qA:99.37"],["4WNU_C_QDNC602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",7,"LEU A 110;PHE A 120;GLY A 212;PHE A 247;ALA A 300;ASP A 301;SER A 304","None;HEM A 600 (-4.6A);None;None;None;None;None","0.61A","4wnuC-2f9qA:55.2","4wnuC-2f9qA:99.37"],["4WNU_C_QDNC602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"LEU A 248;PHE A 120;GLY A 212;GLN A 244;ASP A 301;SER A 304","None;HEM A 600 (-4.6A);None;None;None;None","1.47A","4wnuC-2f9qA:55.2","4wnuC-2f9qA:99.37"],["4WNU_D_QDND602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A 120;GLY A 212;GLN A 244;ASP A 301;ALA A 305","HEM A 600 (-4.6A);None;None;None;HEM A 600 (-3.6A)","1.05A","4wnuD-2f9qA:55.5","4wnuD-2f9qA:99.37"],["4WNU_D_QDND602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A 120;GLY A 212;GLU A 216;GLN A 244;ALA A 305","HEM A 600 (-4.6A);None;None;None;HEM A 600 (-3.6A)","1.27A","4wnuD-2f9qA:55.5","4wnuD-2f9qA:99.37"],["4WNU_D_QDND602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A 120;GLY A 212;GLU A 216;LEU A 251;ALA A 305","HEM A 600 (-4.6A);None;None;None;HEM A 600 (-3.6A)","1.30A","4wnuD-2f9qA:55.5","4wnuD-2f9qA:99.37"],["4WNU_D_QDND602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",8,"PHE A 120;GLY A 212;PHE A 247;LEU A 248;ALA A 300;ASP A 301;SER A 304;ALA A 305","HEM A 600 (-4.6A);None;None;None;None;None;None;HEM A 600 (-3.6A)","0.53A","4wnuD-2f9qA:55.5","4wnuD-2f9qA:99.37"],["4WNV_A_QI9A602_0","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"LEU A 121;SER A 304;THR A 309;PHE A 483;LEU A 484","None;None;HEM A 600 (-3.5A);None;None","1.48A","4wnvA-2f9qA:54.4","4wnvA-2f9qA:99.37"],["4WNV_A_QI9A602_0","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A 120;LEU A 121;GLU A 216;SER A 304;THR A 309","HEM A 600 (-4.6A);None;None;None;HEM A 600 (-3.5A)","1.02A","4wnvA-2f9qA:54.4","4wnvA-2f9qA:99.37"],["4WNV_A_QI9A602_0","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"PHE A 120;LEU A 121;SER A 304;THR A 309;VAL A 370;LEU A 484","HEM A 600 (-4.6A);None;None;HEM A 600 (-3.5A);HEM A 600 ( 4.9A);None","0.66A","4wnvA-2f9qA:54.4","4wnvA-2f9qA:99.37"],["4WNV_B_QI9B602_0","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A 120;LEU A 121;GLU A 216;SER A 304;THR A 309","HEM A 600 (-4.6A);None;None;None;HEM A 600 (-3.5A)","1.06A","4wnvB-2f9qA:55.7","4wnvB-2f9qA:99.37"],["4WNV_B_QI9B602_0","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A 120;LEU A 121;SER A 304;THR A 309;VAL A 370","HEM A 600 (-4.6A);None;None;HEM A 600 (-3.5A);HEM A 600 ( 4.9A)","0.58A","4wnvB-2f9qA:55.7","4wnvB-2f9qA:99.37"],["4WNV_C_QI9C602_0","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"LEU A 121;ASP A 301;SER A 304;THR A 309;PHE A 483","None;None;None;HEM A 600 (-3.5A);None","1.22A","4wnvC-2f9qA:55.1","4wnvC-2f9qA:99.37"],["4WNV_C_QI9C602_0","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"PHE A 120;LEU A 121;ASP A 301;SER A 304;THR A 309;VAL A 370","HEM A 600 (-4.6A);None;None;None;HEM A 600 (-3.5A);HEM A 600 ( 4.9A)","0.60A","4wnvC-2f9qA:55.1","4wnvC-2f9qA:99.37"],["4WNV_D_QI9D602_0","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"PHE A 120;LEU A 121;GLU A 216;SER A 304;THR A 309","HEM A 600 (-4.6A);None;None;None;HEM A 600 (-3.5A)","1.10A","4wnvD-2f9qA:55.5","4wnvD-2f9qA:99.37"],["4WNW_A_RTZA602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",7,"PHE A 112;PHE A 120;GLY A 212;ASP A 301;SER A 304;VAL A 308;THR A 309","None;HEM A 600 (-4.6A);None;None;None;None;HEM A 600 (-3.5A)","0.98A","4wnwA-2f9qA:50.6","4wnwA-2f9qA:99.37"],["4WNW_A_RTZA602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",8,"PHE A 112;PHE A 120;GLY A 212;LEU A 213;GLN A 244;ASP A 301;VAL A 308;THR A 309","None;HEM A 600 (-4.6A);None;None;None;None;None;HEM A 600 (-3.5A)","1.30A","4wnwA-2f9qA:50.6","4wnwA-2f9qA:99.37"],["4WNW_B_RTZB602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"PHE A 112;PHE A 120;GLY A 212;LEU A 213;ASP A 301;VAL A 308","None;HEM A 600 (-4.6A);None;None;None;None","1.10A","4wnwB-2f9qA:51.5","4wnwB-2f9qA:99.37"],["4WNW_B_RTZB602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"PHE A 112;PHE A 120;GLY A 212;LEU A 213;GLN A 244;VAL A 308","None;HEM A 600 (-4.6A);None;None;None;None","1.36A","4wnwB-2f9qA:51.5","4wnwB-2f9qA:99.37"],["4WNW_B_RTZB602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",7,"PHE A 112;PHE A 120;LEU A 121;GLY A 212;ALA A 300;ASP A 301;SER A 304","None;HEM A 600 (-4.6A);None;None;None;None;None","0.73A","4wnwB-2f9qA:51.5","4wnwB-2f9qA:99.37"],["4WNW_B_RTZB602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"PHE A 112;PHE A 120;LEU A 121;GLY A 212;ASP A 301;VAL A 308","None;HEM A 600 (-4.6A);None;None;None;None","0.91A","4wnwB-2f9qA:51.5","4wnwB-2f9qA:99.37"],["4WNW_B_RTZB602_1","CYTOCHROME P450 2D6","2f9q","CYTOCHROME P450 2D6","Homo sapiens",6,"PHE A 112;PHE A 120;LEU A 121;GLY A 212;GLN A 244;VAL A 308","None;HEM A 600 (-4.6A);None;None;None;None","1.27A","4wnwB-2f9qA:51.5","4wnwB-2f9qA:99.37"],["4X1I_B_LOCB502_2","TUBULIN BETA CHAIN","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"LEU A 208;ALA A 246;LEU A 248;ALA A 300;ALA A 209","None","1.23A","4x1iB-2f9qA:undetectable","4x1iB-2f9qA:21.97"],["4XR4_B_AG2B511_1","HOMOSPERMIDINE SYNTHASE","2f9q","CYTOCHROME P450 2D6","Homo sapiens",3,"VAL A 104;PHE A 120;ARG A 441","None;HEM A 600 (-4.6A);HEM A 600 (-3.5A)","0.97A","4xr4B-2f9qA:undetectable","4xr4B-2f9qA:21.54"],["5MM4_B_TA1B501_1","TUBULIN BETA CHAIN","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"VAL A 308;LEU A 248;ALA A 305;PHE A 120;LEU A 220","None;None;HEM A 600 (-3.6A);HEM A 600 (-4.6A);None","1.28A","5mm4B-2f9qA:undetectable","5mm4B-2f9qA:10.42"],["5NWW_A_ACAA18_2","SCRFP-TAG,GP41","2f9q","CYTOCHROME P450 2D6","Homo sapiens",3,"LYS A 404;TRP A 409;SER A 400","None","1.25A","5nwwA-2f9qA:undetectable","5nwwA-2f9qA:6.72"],["6BKL_C_EU7C101_0","MATRIX PROTEIN 2","2f9q","CYTOCHROME P450 2D6","Homo sapiens",5,"ALA A 127;SER A 289;VAL A 119;ALA A 122;VAL A 298","None;None;HEM A 600 (-4.6A);None;None","0.98A","6bklA-2f9qA:undetectable;6bklB-2f9qA:undetectable;6bklC-2f9qA:undetectable;6bklD-2f9qA:undetectable","6bklA-2f9qA:4.46;6bklB-2f9qA:4.46;6bklC-2f9qA:4.46;6bklD-2f9qA:4.46"],["6BRD_A_RFPA502_2","RIFAMPIN MONOOXYGENASE","2f9q","CYTOCHROME P450 2D6","Homo sapiens",4,"GLN A 332;VAL A 359;ARG A 344;ARG A 497","None","1.40A","6brdA-2f9qA:0.0","6brdA-2f9qA:12.39"],["6ECE_C_DVAC3010_0","VLM2;DODECADEPSIPEPTIDE","2f9q","CYTOCHROME P450 2D6","Homo sapiens",3,"ALA A 274;PHE A 290;GLN A 131","None","0.83A","6eceA-2f9qA:undetectable","6eceA-2f9qA:23.28"]]