SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f9t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 236
VAL A 239
LEU A 243
 None
 0.50A 1mz9B-2f9tA:
undetectable		 1mz9B-2f9tA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		4 / 8 ASN A  90
TYR A  95
LEU A  98
GLY A  99
 None
 0.83A 1rukH-2f9tA:
undetectable
1rukL-2f9tA:
undetectable		 1rukH-2f9tA:
23.32
1rukL-2f9tA:
18.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		8 / 11 ASN A   9
VAL A  55
TYR A  92
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.45A 2f9wA-2f9tA:
38.8
2f9wB-2f9tA:
37.9		 2f9wA-2f9tA:
100.00
2f9wB-2f9tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		6 / 8 TYR A  92
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.23A 2f9wA-2f9tA:
38.8
2f9wB-2f9tA:
37.9		 2f9wA-2f9tA:
100.00
2f9wB-2f9tA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		6 / 10 ASN A   9
VAL A  55
GLY A  99
ASP A 101
ARG A 102
THR A 127
 None
 0.58A 3bexA-2f9tA:
24.0
3bexB-2f9tA:
23.9		 3bexA-2f9tA:
27.37
3bexB-2f9tA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		6 / 9 ASN A   9
VAL A  55
GLY A  99
ASP A 101
ARG A 102
THR A 127
 None
 0.58A 3bexA-2f9tA:
24.0
3bexB-2f9tA:
23.9		 3bexA-2f9tA:
27.37
3bexB-2f9tA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		7 / 11 ASN A   9
VAL A  55
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.57A 3bexC-2f9tA:
23.9
3bexD-2f9tA:
23.9		 3bexC-2f9tA:
27.37
3bexD-2f9tA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		7 / 10 ASN A   9
VAL A  55
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.55A 3bexC-2f9tA:
23.9
3bexD-2f9tA:
23.9		 3bexC-2f9tA:
27.37
3bexD-2f9tA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		7 / 10 ASN A   9
VAL A  55
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.56A 3bexE-2f9tA:
24.1
3bexF-2f9tA:
24.1		 3bexE-2f9tA:
27.37
3bexF-2f9tA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		7 / 11 ASN A   9
VAL A  55
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.58A 3bexE-2f9tA:
24.1
3bexF-2f9tA:
24.1		 3bexE-2f9tA:
27.37
3bexF-2f9tA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		7 / 11 ASN A   9
VAL A  55
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.63A 3bf1A-2f9tA:
24.1
3bf1B-2f9tA:
24.2		 3bf1A-2f9tA:
27.37
3bf1B-2f9tA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		7 / 12 ASN A   9
VAL A  55
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.61A 3bf1A-2f9tA:
24.1
3bf1B-2f9tA:
24.2		 3bf1A-2f9tA:
27.37
3bf1B-2f9tA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		7 / 11 ASN A   9
VAL A  55
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.57A 3bf1C-2f9tA:
24.2
3bf1D-2f9tA:
24.1		 3bf1C-2f9tA:
27.37
3bf1D-2f9tA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		7 / 11 ASN A   9
VAL A  55
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.56A 3bf1C-2f9tA:
24.2
3bf1D-2f9tA:
24.1		 3bf1C-2f9tA:
27.37
3bf1D-2f9tA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		7 / 11 ASN A   9
VAL A  55
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.58A 3bf1E-2f9tA:
24.3
3bf1F-2f9tA:
24.0		 3bf1E-2f9tA:
27.37
3bf1F-2f9tA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		7 / 11 ASN A   9
VAL A  55
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.57A 3bf1E-2f9tA:
24.3
3bf1F-2f9tA:
24.2		 3bf1E-2f9tA:
27.37
3bf1F-2f9tA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		3 / 3 GLY A 139
ASP A 129
SER A 128
 None
 0.61A 3brfA-2f9tA:
undetectable		 3brfA-2f9tA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		5 / 12 THR A 147
GLY A 217
GLY A 123
ILE A 120
VAL A 223
 None
 1.25A 3fzgA-2f9tA:
undetectable		 3fzgA-2f9tA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A  35
ARG A  67
ALA A  66
GLY A   8
 None
 0.91A 3ny4A-2f9tA:
undetectable		 3ny4A-2f9tA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 129
GLY A 140
GLY A  99
THR A 127
ILE A 142
 None
 1.13A 3prsA-2f9tA:
undetectable		 3prsA-2f9tA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A  27
LEU A   5
LEU A  35
LEU A  28
ILE A  12
 None
 1.09A 3wdmB-2f9tA:
undetectable		 3wdmB-2f9tA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		5 / 9 GLY A  27
LEU A   5
LEU A  35
LEU A  28
ILE A  12
 None
 1.07A 3wdmC-2f9tA:
undetectable		 3wdmC-2f9tA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		3 / 3 SER A  10
ASP A 121
ASP A 129
 None
 0.91A 4mwzA-2f9tA:
undetectable		 4mwzA-2f9tA:
22.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		9 / 12 ASN A   9
VAL A  55
TYR A  92
LEU A  98
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.65A 4o5fA-2f9tA:
25.0
4o5fB-2f9tA:
25.2		 4o5fA-2f9tA:
32.09
4o5fB-2f9tA:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		9 / 12 ASN A   9
VAL A  55
TYR A  92
LEU A  98
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.64A 4o5fA-2f9tA:
25.0
4o5fB-2f9tA:
25.2		 4o5fA-2f9tA:
32.09
4o5fB-2f9tA:
32.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  66
LEU A  68
LEU A   5
LEU A  35
LEU A  39
 None
 0.95A 4wg0C-2f9tA:
undetectable
4wg0D-2f9tA:
undetectable
4wg0E-2f9tA:
undetectable		 4wg0C-2f9tA:
3.85
4wg0D-2f9tA:
3.85
4wg0E-2f9tA:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  66
LEU A  68
LEU A   5
LEU A  35
LEU A  39
 None
 0.96A 4wg0E-2f9tA:
undetectable
4wg0F-2f9tA:
undetectable
4wg0G-2f9tA:
undetectable		 4wg0E-2f9tA:
3.85
4wg0F-2f9tA:
3.85
4wg0G-2f9tA:
3.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		9 / 12 ASN A   9
VAL A  55
TYR A  92
LEU A  98
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.64A 5b8hA-2f9tA:
12.4
5b8hB-2f9tA:
26.0		 5b8hA-2f9tA:
33.33
5b8hB-2f9tA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		9 / 12 ASN A   9
VAL A  55
TYR A  92
LEU A  98
GLY A  99
ASP A 101
ARG A 102
THR A 127
ILE A 142
 None
 0.65A 5b8hA-2f9tA:
12.4
5b8hB-2f9tA:
26.0		 5b8hA-2f9tA:
33.33
5b8hB-2f9tA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 123
GLY A 145
ILE A 232
GLY A 218
GLY A 217
 None
 0.98A 5wyqA-2f9tA:
undetectable		 5wyqA-2f9tA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A  81
VAL A 237
GLY A 240
ALA A 244
ASN A   9
 None
 1.08A 6bqgA-2f9tA:
undetectable		 6bqgA-2f9tA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 217
LEU A 122
VAL A 239
PHE A 214
 None
 1.06A 6h7lA-2f9tA:
undetectable		 6h7lA-2f9tA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 2f9t PANTOTHENATE KINASE
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 217
LEU A 122
VAL A 239
PHE A 214
 None
 1.05A 6h7lB-2f9tA:
undetectable		 6h7lB-2f9tA:
16.24