SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f9y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HXB_A_ROCA100_4 (HIV-1 PROTEASE)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	4 / 4	GLY B 135 ASP B 106 GLY B 131 THR B 202	None	0.99A	1hxbB-2f9yB: undetectable	1hxbB-2f9yB: 15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHQ_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 8	GLY B 229 GLY B 205 PHE B 227 SER B 207 GLY B 163	None	1.33A	1jhqA-2f9yB: undetectable	1jhqA-2f9yB: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHR_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 9	GLY B 229 GLY B 205 PHE B 227 SER B 207 GLY B 163	None	1.32A	1jhrA-2f9yB: undetectable	1jhrA-2f9yB: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHV_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	4 / 8	GLY B 139 PHE B 142 LEU B 108 ARG B 144	None	0.77A	1jhvA-2f9yB: undetectable	1jhvA-2f9yB: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHV_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 8	GLY B 229 GLY B 205 PHE B 227 SER B 207 GLY B 163	None	1.36A	1jhvA-2f9yB: undetectable	1jhvA-2f9yB: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHY_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 9	GLY B 229 GLY B 205 PHE B 227 SER B 207 GLY B 163	None	1.35A	1jhyA-2f9yB: undetectable	1jhyA-2f9yB: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WG8_B_SAMB3141_0 (PREDICTED S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	PRO B 201 GLY B 205 GLY B 204 GLY B 163 PHE B 142	None	1.20A	1wg8B-2f9yB: undetectable	1wg8B-2f9yB: 26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XOT_A_VDNA101_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	LEU B 64 ILE B 195 SER B 248 SER B 160 PHE B 159	None	1.33A	1xotA-2f9yB: undetectable	1xotA-2f9yB: 23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C6N_B_LPRB705_2 (ANGIOTENSIN-CONVERTI NG ENZYME, SOMATIC ISOFORM)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	3 / 3	ALA B 211 THR B 202 PHE B 142	None	0.79A	2c6nB-2f9yB: undetectable	2c6nB-2f9yB: 18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J2P_F_SC2F1291_1 (FICOLIN-2)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN (Escherichia coli)	4 / 6	LEU A 146 ASP A 97 ASP A 98 GLU A 88	None	1.15A	2j2pE-2f9yA: undetectable 2j2pF-2f9yA: undetectable	2j2pE-2f9yA: 17.42 2j2pF-2f9yA: 17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O5Y_H_STRH249_1 (CHIMERIC ANTIBODY FAB 1E9-DB3)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	4 / 7	ASN B 217 GLY B 214 MET B 212 SER B 160	None	1.03A	2o5yH-2f9yB: undetectable 2o5yL-2f9yB: undetectable	2o5yH-2f9yB: 20.88 2o5yL-2f9yB: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PGR_A_DCFA501_2 (ADENOSINE DEAMINASE)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN (Escherichia coli)	3 / 3	LEU A 58 LEU A 272 PHE A 8	None	0.62A	2pgrA-2f9yA: undetectable	2pgrA-2f9yA: 24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PIW_A_T3A933_1 (ANDROGEN RECEPTOR)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 10	ILE A 253 GLY A 206 PHE B 227 GLU A 202 ARG A 68	None	1.40A	2piwA-2f9yA: 0.0	2piwA-2f9yA: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_D_KLND1499_1 (CYTOCHROME P450 3A4)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	4 / 5	PHE B 125 SER B 248 PHE B 210 ILE B 260	None	1.40A	2v0mD-2f9yB: undetectable	2v0mD-2f9yB: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WD9_C_IBPC1570_1 (ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN (Escherichia coli)	5 / 10	ILE A 253 VAL A 199 GLY A 201 GLY A 203 ARG A 68	None	1.24A	2wd9C-2f9yA: undetectable	2wd9C-2f9yA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WD9_C_IBPC1570_1 (ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN (Escherichia coli)	5 / 10	ILE A 253 VAL A 199 GLY A 201 GLY A 204 ARG A 68	None	1.06A	2wd9C-2f9yA: undetectable	2wd9C-2f9yA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XN5_A_FUNA1356_2 (THYROXINE-BINDING GLOBULIN)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	3 / 3	LEU B 251 ARG B 247 ILE B 252	None	0.64A	2xn5B-2f9yB: undetectable	2xn5B-2f9yB: 7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	4 / 6	ARG A 257 GLY A 252 ALA B 170 LEU A 261	None	0.95A	3bgdA-2f9yA: undetectable	3bgdA-2f9yA: 27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM0_B_CHDB151_0 (ILEAL BILE ACID-BINDING PROTEIN)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN (Escherichia coli)	5 / 12	ILE A 115 ILE A 158 VAL A 196 LYS A 216 LEU A 220	None	1.09A	3em0B-2f9yA: undetectable	3em0B-2f9yA: 17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB1_A_SAMA1101_0 (STRUCTURAL PROTEIN VP3)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN (Escherichia coli)	5 / 12	ARG A 141 ALA A 136 ALA A 94 ILE A 101 ALA A 143	None	1.04A	3jb1A-2f9yA: undetectable	3jb1A-2f9yA: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K4V_D_ROCD201_2 (HIV-1 PROTEASE)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	4 / 4	GLY B 135 ASP B 106 GLY B 131 THR B 202	None	1.00A	3k4vC-2f9yB: undetectable	3k4vC-2f9yB: 16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LW5_B_PQNB5002_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 10	ILE A 264 SER B 209 ALA A 210 LEU A 209 ALA B 178	None	1.33A	3lw5B-2f9yA: undetectable	3lw5B-2f9yA: 17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NHX_A_ASDA126_1 (STEROID DELTA-ISOMERASE)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	TYR B 194 LEU B 184 SER B 209 VAL B 138 PHE B 125	None	1.24A	3nhxA-2f9yB: 0.0	3nhxA-2f9yB: 17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9T_C_BEZC264_0 (ECHA1_1)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN (Escherichia coli)	4 / 5	ALA A 64 GLU A 231 ALA A 244 MET A 251	None	1.45A	3r9tC-2f9yA: 10.8	3r9tC-2f9yA: 23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFN_A_ROCA401_1 (HIV-1 PROTEASE)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN (Escherichia coli)	5 / 11	ALA A 90 VAL A 102 GLY A 103 GLY A 104 ILE A 105	None	0.81A	3ufnA-2f9yA: undetectable	3ufnA-2f9yA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KQI_A_NIOA403_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 9	GLY B 229 GLY B 205 PHE B 227 SER B 207 GLY B 163	None	1.29A	4kqiA-2f9yB: undetectable	4kqiA-2f9yB: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM9_A_FVXA603_1 (TRANSPORTER)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 11	ALA A 180 TYR A 140 GLY B 204 PHE B 227 SER B 209	None	1.23A	4mm9A-2f9yA: undetectable	4mm9A-2f9yA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MMD_B_29EB603_1 (TRANSPORTER)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	ALA A 180 TYR A 140 GLY B 204 PHE B 227 SER B 209	None	1.19A	4mmdB-2f9yA: undetectable	4mmdB-2f9yA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OU1_A_BEZA302_0 (RETRO-ALDOLASE, DESIGN RA114)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN (Escherichia coli)	4 / 8	ILE A 116 ILE A 211 ASN A 184 ALA A 210	None	0.96A	4ou1A-2f9yA: undetectable	4ou1A-2f9yA: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5C0O_G_SAMG301_0 (TRNA (ADENINE(58)-N(1))-M ETHYLTRANSFERASE TRMI)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	ALA B 107 GLY B 135 GLY B 164 ALA B 140 ARG B 141	None	0.97A	5c0oG-2f9yB: undetectable	5c0oG-2f9yB: 24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D4N_C_ACTC201_0 (NITROGEN REGULATORY PROTEIN P-II)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	4 / 5	VAL B 206 VAL B 138 GLY B 135 PHE B 125	None	1.11A	5d4nA-2f9yB: undetectable 5d4nC-2f9yB: undetectable	5d4nA-2f9yB: 17.38 5d4nC-2f9yB: 17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G44_A_YTZA1512_1 (NUCLEAR RECEPTOR ROR-GAMMA)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 9	LEU B 61 ALA B 107 VAL B 138 ARG B 141 ALA B 123	None	1.21A	5g44A-2f9yB: undetectable	5g44A-2f9yB: 22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HS1_A_VORA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	4 / 8	PHE B 227 ILE A 181 GLY A 165 LEU B 171	None	0.82A	5hs1A-2f9yB: undetectable	5hs1A-2f9yB: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JWA_H_ACTH612_0 (NADH DEHYDROGENASE, PUTATIVE)	2f9y	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	3 / 3	ARG B 262 PRO B 264 ASN B 42	None	0.82A	5jwaA-2f9yB: undetectable 5jwaH-2f9yB: undetectable	5jwaA-2f9yB: 18.86 5jwaH-2f9yB: 18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OY0_2_PQN2843_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	ILE A 264 SER B 209 ALA A 210 LEU A 209 ALA B 178	None	1.30A	5oy02-2f9yA: undetectable	5oy02-2f9yA: 12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5P9I_A_1E8A701_2 (TYROSINE-PROTEIN KINASE BTK)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN (Escherichia coli)	4 / 5	LEU A 220 TYR A 78 CYH A 197 ASP A 293	None	1.23A	5p9iA-2f9yA: 0.0	5p9iA-2f9yA: 21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UL4_A_SAMA803_0 (OXSB PROTEIN)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli; Escherichia coli)	5 / 12	ALA B 178 GLY A 212 GLY A 214 ILE A 157 GLU A 151	None	1.04A	5ul4A-2f9yB: undetectable	5ul4A-2f9yB: 17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_2 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN (Escherichia coli)	4 / 4	VAL A 299 LEU A 300 LEU A 305 ASP A 215	None	1.16A	5xv7A-2f9yA: undetectable	5xv7A-2f9yA: 11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y2T_A_8LXA501_0 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (Escherichia coli; Escherichia coli)	5 / 12	GLY B 205 TYR B 194 LEU B 213 ILE A 181 LEU B 108	None	1.22A	5y2tA-2f9yB: undetectable	5y2tA-2f9yB: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6D8P_A_ACTA816_0 (UNCHARACTERIZED PROTEIN)	2f9y	ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN (Escherichia coli)	3 / 3	ARG A 308 ARG A 309 ASP A 215	None	0.83A	6d8pA-2f9yA: undetectable	6d8pA-2f9yA: 19.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HXB_A_ROCA100_4","HIV-1 PROTEASE;HIV-1 PROTEASE","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",4,"GLY B 135;ASP B 106;GLY B 131;THR B 202","None","0.99A","1hxbB-2f9yB:undetectable","1hxbB-2f9yB:15.71"],["1JHQ_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"GLY B 229;GLY B 205;PHE B 227;SER B 207;GLY B 163","None","1.33A","1jhqA-2f9yB:undetectable","1jhqA-2f9yB:24.32"],["1JHR_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"GLY B 229;GLY B 205;PHE B 227;SER B 207;GLY B 163","None","1.32A","1jhrA-2f9yB:undetectable","1jhrA-2f9yB:24.32"],["1JHV_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",4,"GLY B 139;PHE B 142;LEU B 108;ARG B 144","None","0.77A","1jhvA-2f9yB:undetectable","1jhvA-2f9yB:24.32"],["1JHV_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"GLY B 229;GLY B 205;PHE B 227;SER B 207;GLY B 163","None","1.36A","1jhvA-2f9yB:undetectable","1jhvA-2f9yB:24.32"],["1JHY_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"GLY B 229;GLY B 205;PHE B 227;SER B 207;GLY B 163","None","1.35A","1jhyA-2f9yB:undetectable","1jhyA-2f9yB:24.32"],["1WG8_B_SAMB3141_0","PREDICTED S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"PRO B 201;GLY B 205;GLY B 204;GLY B 163;PHE B 142","None","1.20A","1wg8B-2f9yB:undetectable","1wg8B-2f9yB:26.18"],["1XOT_A_VDNA101_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"LEU B  64;ILE B 195;SER B 248;SER B 160;PHE B 159","None","1.33A","1xotA-2f9yB:undetectable","1xotA-2f9yB:23.43"],["2C6N_B_LPRB705_2","ANGIOTENSIN-CONVERTING ENZYME, SOMATIC ISOFORM","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",3,"ALA B 211;THR B 202;PHE B 142","None","0.79A","2c6nB-2f9yB:undetectable","2c6nB-2f9yB:18.73"],["2J2P_F_SC2F1291_1","FICOLIN-2;FICOLIN-2","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN","Escherichia coli",4,"LEU A 146;ASP A  97;ASP A  98;GLU A  88","None","1.15A","2j2pE-2f9yA:undetectable;2j2pF-2f9yA:undetectable","2j2pE-2f9yA:17.42;2j2pF-2f9yA:17.42"],["2O5Y_H_STRH249_1","CHIMERIC ANTIBODY FAB 1E9-DB3;CHIMERIC ANTIBODY FAB 1E9-DB3","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",4,"ASN B 217;GLY B 214;MET B 212;SER B 160","None","1.03A","2o5yH-2f9yB:undetectable;2o5yL-2f9yB:undetectable","2o5yH-2f9yB:20.88;2o5yL-2f9yB:21.14"],["2PGR_A_DCFA501_2","ADENOSINE DEAMINASE","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN","Escherichia coli",3,"LEU A  58;LEU A 272;PHE A   8","None","0.62A","2pgrA-2f9yA:undetectable","2pgrA-2f9yA:24.88"],["2PIW_A_T3A933_1","ANDROGEN RECEPTOR","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN;ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"ILE A 253;GLY A 206;PHE B 227;GLU A 202;ARG A  68","None","1.40A","2piwA-2f9yA:0.0","2piwA-2f9yA:19.27"],["2V0M_D_KLND1499_1","CYTOCHROME P450 3A4","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",4,"PHE B 125;SER B 248;PHE B 210;ILE B 260","None","1.40A","2v0mD-2f9yB:undetectable","2v0mD-2f9yB:20.73"],["2WD9_C_IBPC1570_1","ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN","Escherichia coli",5,"ILE A 253;VAL A 199;GLY A 201;GLY A 203;ARG A  68","None","1.24A","2wd9C-2f9yA:undetectable","2wd9C-2f9yA:21.99"],["2WD9_C_IBPC1570_1","ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN","Escherichia coli",5,"ILE A 253;VAL A 199;GLY A 201;GLY A 204;ARG A  68","None","1.06A","2wd9C-2f9yA:undetectable","2wd9C-2f9yA:21.99"],["2XN5_A_FUNA1356_2","THYROXINE-BINDING GLOBULIN;THYROXINE-BINDING GLOBULIN","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",3,"LEU B 251;ARG B 247;ILE B 252","None","0.64A","2xn5B-2f9yB:undetectable","2xn5B-2f9yB:7.89"],["3BGD_A_PM6A301_1","THIOPURINE S-METHYLTRANSFERASE","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN;ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",4,"ARG A 257;GLY A 252;ALA B 170;LEU A 261","None","0.95A","3bgdA-2f9yA:undetectable","3bgdA-2f9yA:27.84"],["3EM0_B_CHDB151_0","ILEAL BILE ACID-BINDING PROTEIN","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN","Escherichia coli",5,"ILE A 115;ILE A 158;VAL A 196;LYS A 216;LEU A 220","None","1.09A","3em0B-2f9yA:undetectable","3em0B-2f9yA:17.58"],["3JB1_A_SAMA1101_0","STRUCTURAL PROTEIN VP3","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN","Escherichia coli",5,"ARG A 141;ALA A 136;ALA A  94;ILE A 101;ALA A 143","None","1.04A","3jb1A-2f9yA:undetectable","3jb1A-2f9yA:16.03"],["3K4V_D_ROCD201_2","HIV-1 PROTEASE;HIV-1 PROTEASE","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",4,"GLY B 135;ASP B 106;GLY B 131;THR B 202","None","1.00A","3k4vC-2f9yB:undetectable","3k4vC-2f9yB:16.07"],["3LW5_B_PQNB5002_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN;ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"ILE A 264;SER B 209;ALA A 210;LEU A 209;ALA B 178","None","1.33A","3lw5B-2f9yA:undetectable","3lw5B-2f9yA:17.90"],["3NHX_A_ASDA126_1","STEROID DELTA-ISOMERASE","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"TYR B 194;LEU B 184;SER B 209;VAL B 138;PHE B 125","None","1.24A","3nhxA-2f9yB:0.0","3nhxA-2f9yB:17.97"],["3R9T_C_BEZC264_0","ECHA1_1","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN","Escherichia coli",4,"ALA A  64;GLU A 231;ALA A 244;MET A 251","None","1.45A","3r9tC-2f9yA:10.8","3r9tC-2f9yA:23.33"],["3UFN_A_ROCA401_1","HIV-1 PROTEASE","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN","Escherichia coli",5,"ALA A  90;VAL A 102;GLY A 103;GLY A 104;ILE A 105","None","0.81A","3ufnA-2f9yA:undetectable","3ufnA-2f9yA:16.67"],["4KQI_A_NIOA403_1","NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"GLY B 229;GLY B 205;PHE B 227;SER B 207;GLY B 163","None","1.29A","4kqiA-2f9yB:undetectable","4kqiA-2f9yB:24.32"],["4MM9_A_FVXA603_1","TRANSPORTER","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN;ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"ALA A 180;TYR A 140;GLY B 204;PHE B 227;SER B 209","None","1.23A","4mm9A-2f9yA:undetectable","4mm9A-2f9yA:20.70"],["4MMD_B_29EB603_1","TRANSPORTER","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN;ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"ALA A 180;TYR A 140;GLY B 204;PHE B 227;SER B 209","None","1.19A","4mmdB-2f9yA:undetectable","4mmdB-2f9yA:21.59"],["4OU1_A_BEZA302_0","RETRO-ALDOLASE, DESIGN RA114","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN","Escherichia coli",4,"ILE A 116;ILE A 211;ASN A 184;ALA A 210","None","0.96A","4ou1A-2f9yA:undetectable","4ou1A-2f9yA:21.74"],["5C0O_G_SAMG301_0","TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRMI","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"ALA B 107;GLY B 135;GLY B 164;ALA B 140;ARG B 141","None","0.97A","5c0oG-2f9yB:undetectable","5c0oG-2f9yB:24.85"],["5D4N_C_ACTC201_0","NITROGEN REGULATORY PROTEIN P-II","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",4,"VAL B 206;VAL B 138;GLY B 135;PHE B 125","None","1.11A","5d4nA-2f9yB:undetectable;5d4nC-2f9yB:undetectable","5d4nA-2f9yB:17.38;5d4nC-2f9yB:17.38"],["5G44_A_YTZA1512_1","NUCLEAR RECEPTOR ROR-GAMMA","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"LEU B  61;ALA B 107;VAL B 138;ARG B 141;ALA B 123","None","1.21A","5g44A-2f9yB:undetectable","5g44A-2f9yB:22.98"],["5HS1_A_VORA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN;ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",4,"PHE B 227;ILE A 181;GLY A 165;LEU B 171","None","0.82A","5hs1A-2f9yB:undetectable","5hs1A-2f9yB:22.22"],["5JWA_H_ACTH612_0","NADH DEHYDROGENASE, PUTATIVE","2f9y","ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",3,"ARG B 262;PRO B 264;ASN B  42","None","0.82A","5jwaA-2f9yB:undetectable;5jwaH-2f9yB:undetectable","5jwaA-2f9yB:18.86;5jwaH-2f9yB:18.86"],["5OY0_2_PQN2843_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN;ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"ILE A 264;SER B 209;ALA A 210;LEU A 209;ALA B 178","None","1.30A","5oy02-2f9yA:undetectable","5oy02-2f9yA:12.78"],["5P9I_A_1E8A701_2","TYROSINE-PROTEIN KINASE BTK","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN","Escherichia coli",4,"LEU A 220;TYR A  78;CYH A 197;ASP A 293","None","1.23A","5p9iA-2f9yA:0.0","5p9iA-2f9yA:21.08"],["5UL4_A_SAMA803_0","OXSB PROTEIN","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN;ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli;Escherichia coli",5,"ALA B 178;GLY A 212;GLY A 214;ILE A 157;GLU A 151","None","1.04A","5ul4A-2f9yB:undetectable","5ul4A-2f9yB:17.50"],["5XV7_A_EMHA705_2","SERINE-ARGININE (SR) PROTEIN KINASE 1","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN","Escherichia coli",4,"VAL A 299;LEU A 300;LEU A 305;ASP A 215","None","1.16A","5xv7A-2f9yA:undetectable","5xv7A-2f9yA:11.57"],["5Y2T_A_8LXA501_0","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN;ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA","Escherichia coli;Escherichia coli",5,"GLY B 205;TYR B 194;LEU B 213;ILE A 181;LEU B 108","None","1.22A","5y2tA-2f9yB:undetectable","5y2tA-2f9yB:undetectable"],["6D8P_A_ACTA816_0","UNCHARACTERIZED PROTEIN","2f9y","ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE ALPHA CHAIN","Escherichia coli",3,"ARG A 308;ARG A 309;ASP A 215","None","0.83A","6d8pA-2f9yA:undetectable","6d8pA-2f9yA:19.18"]]