SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f9z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2f9z CHEMOTAXIS PROTEIN
CHEC
PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		5 / 11 ARG C 130
GLY C 101
GLU A 151
ASN C  99
ILE C 100
 None
 1.16A 1odiC-2f9zC:
undetectable		 1odiC-2f9zC:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		4 / 4 SER A  37
ILE A  36
VAL A 174
THR A  82
 None
 1.25A 1u70A-2f9zA:
undetectable		 1u70A-2f9zA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		3 / 3 GLU A 112
GLU A 104
LEU A  88
 None
 0.60A 1v8bA-2f9zA:
undetectable		 1v8bA-2f9zA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		3 / 3 GLU A 112
GLU A 104
LEU A  88
 None
 0.58A 1v8bB-2f9zA:
undetectable		 1v8bB-2f9zA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		5 / 12 GLY A  80
SER A 183
ALA A  53
ILE A  59
PHE A 149
 None
 0.94A 1ve3A-2f9zA:
undetectable		 1ve3A-2f9zA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		5 / 12 GLY A  80
SER A 183
ALA A  53
ILE A  59
PHE A 149
 None
 0.95A 1ve3B-2f9zA:
undetectable		 1ve3B-2f9zA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		5 / 10 LEU A 129
LEU A 125
ILE A 197
GLU A 169
MET A 187
 None
 1.11A 1wopA-2f9zA:
undetectable		 1wopA-2f9zA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		5 / 12 PHE A 198
LEU A 129
MET A 201
ILE A 165
VAL A  41
 None
 1.17A 2hrcB-2f9zA:
undetectable		 2hrcB-2f9zA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		5 / 12 GLY A 114
ASN A 115
ILE A  78
GLY A  80
PRO A 138
 None
 1.11A 3eeyD-2f9zA:
undetectable		 3eeyD-2f9zA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 2f9z PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		4 / 6 ILE C  86
TYR C 134
ILE C 117
HIS C 111
 None
 1.12A 3eteA-2f9zC:
2.7
3eteE-2f9zC:
2.7		 3eteA-2f9zC:
18.71
3eteE-2f9zC:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 2f9z PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		4 / 5 ILE C  86
TYR C 134
ILE C 117
HIS C 111
 None
 1.13A 3eteB-2f9zC:
undetectable
3eteC-2f9zC:
undetectable		 3eteB-2f9zC:
18.71
3eteC-2f9zC:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 2f9z PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		4 / 7 ILE C 117
HIS C 111
ILE C  86
TYR C 134
 None
 1.13A 3eteD-2f9zC:
2.7
3eteF-2f9zC:
2.7		 3eteD-2f9zC:
18.71
3eteF-2f9zC:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		5 / 12 LEU A 102
GLY A  93
ILE A  30
LEU A 110
ILE A 113
 None
 1.12A 3ijdB-2f9zA:
undetectable		 3ijdB-2f9zA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2f9z PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		5 / 9 VAL C 132
LEU C 119
ILE C  86
ALA C  87
GLU C 122
 None
 1.14A 3mdvA-2f9zC:
undetectable		 3mdvA-2f9zC:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 2f9z PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		5 / 12 GLY C 139
VAL C  18
ASN C 135
ALA C  29
LEU C 120
 None
 1.25A 3mteA-2f9zC:
undetectable		 3mteA-2f9zC:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		5 / 9 ALA A  23
ILE A  26
MET A 117
GLY A  18
ILE A  17
 None
 1.01A 3ogpB-2f9zA:
undetectable		 3ogpB-2f9zA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 2f9z PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		5 / 12 GLY C  89
GLY C 125
ASN C  99
ALA C  29
LEU C  24
 None
 1.26A 3vywB-2f9zC:
undetectable		 3vywB-2f9zC:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 2f9z PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		5 / 12 GLY C  89
GLY C 125
ASN C  99
ALA C  29
LEU C  24
 None
 1.21A 3vywD-2f9zC:
undetectable		 3vywD-2f9zC:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		5 / 12 GLY A  15
GLY A  18
LEU A 125
VAL A 168
VAL A 166
 None
 0.92A 4htfA-2f9zA:
undetectable		 4htfA-2f9zA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		5 / 12 GLY A  15
GLY A  18
LEU A 125
VAL A 168
VAL A 166
 None
 0.94A 4htfB-2f9zA:
undetectable		 4htfB-2f9zA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_A_LYAA304_1
(FOLATE RECEPTOR BETA)		 2f9z CHEMOTAXIS PROTEIN
CHEC
PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		5 / 12 ASP C  62
THR C  63
TYR C  60
SER A 161
GLY C  25
 None
 1.48A 4kn2A-2f9zC:
undetectable		 4kn2A-2f9zC:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_1
(FOLATE RECEPTOR BETA)		 2f9z CHEMOTAXIS PROTEIN
CHEC
PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		5 / 12 ASP C  62
THR C  63
TYR C  60
SER A 161
GLY C  25
 None
 1.39A 4kn2C-2f9zC:
undetectable		 4kn2C-2f9zC:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2f9z PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		4 / 6 TYR C 134
VAL C  30
ILE C 117
LEU C  72
 None
 0.96A 4l1wB-2f9zC:
undetectable		 4l1wB-2f9zC:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		4 / 8 LEU A 125
VAL A 168
VAL A  75
LEU A  11
 None
 0.97A 4pwdA-2f9zA:
undetectable		 4pwdA-2f9zA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		4 / 7 ILE A  17
GLY A  18
LEU A 194
PHE A 198
 None
 0.90A 5hieB-2f9zA:
undetectable		 5hieB-2f9zA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 2f9z PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		5 / 11 ILE C 157
ASP C 123
THR C 124
VAL C  45
LEU C  24
 None
 1.23A 5jkwA-2f9zC:
undetectable		 5jkwA-2f9zC:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 2f9z CHEMOTAXIS PROTEIN
CHEC
(Thermotoga
maritima) 		5 / 10 ILE A  59
ILE A 142
ILE A 148
ILE A 145
ILE A  78
 None
 1.01A 5murE-2f9zA:
undetectable		 5murE-2f9zA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2f9z PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima) 		6 / 11 LEU C  24
GLY C  89
VAL C  30
THR C 124
GLU C 122
ALA C  87
 None
 1.44A 5o96G-2f9zC:
undetectable		 5o96G-2f9zC:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 2f9z CHEMOTAXIS PROTEIN
CHEC
PROTEIN (CHEMOTAXIS
METHYLATION PROTEIN)
(Thermotoga
maritima;
Thermotoga
maritima) 		5 / 12 GLY C 126
GLY C  25
GLY C  88
ALA A 150
ASP A 143
 None
 1.18A 5x7fA-2f9zC:
undetectable		 5x7fA-2f9zC:
20.82