SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fa1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 2fa1 PROBABLE
TRANSCRIPTIONAL
REGULATOR PHNF
(Escherichia
coli) 		5 / 12 THR A 175
LEU A 159
ALA A 223
ALA A 178
ILE A 130
 None
 1.07A 3czhB-2fa1A:
undetectable		 3czhB-2fa1A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 2fa1 PROBABLE
TRANSCRIPTIONAL
REGULATOR PHNF
(Escherichia
coli) 		3 / 3 ARG A 137
LEU A 135
GLU A 104
 None
 0.72A 4l3gF-2fa1A:
2.1		 4l3gF-2fa1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2fa1 PROBABLE
TRANSCRIPTIONAL
REGULATOR PHNF
(Escherichia
coli) 		3 / 3 SER A 228
SER A 226
PHE A 237
 None
 0.71A 5mugA-2fa1A:
undetectable		 5mugA-2fa1A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_2
(-)		 2fa1 PROBABLE
TRANSCRIPTIONAL
REGULATOR PHNF
(Escherichia
coli) 		4 / 4 GLN A 183
THR A 184
HIS A 168
LEU A 179
 None
 1.49A 6f3nB-2fa1A:
undetectable		 6f3nB-2fa1A:
16.74