SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fb5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		5 / 12 LEU A 183
ALA A  94
VAL A 138
ILE A 126
ILE A  96
 None
 0.89A 2f8gB-2fb5A:
undetectable		 2f8gB-2fb5A:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		4 / 7 ASN A 150
LEU A 139
SER A 147
THR A 113
 None
 1.16A 2uz2A-2fb5A:
undetectable		 2uz2A-2fb5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		4 / 7 ASN A 150
LEU A 139
THR A 113
VAL A 146
 None
 1.04A 2uz2A-2fb5A:
undetectable		 2uz2A-2fb5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		5 / 9 LEU A 114
VAL A 140
ILE A  80
ALA A 148
ILE A 145
 None
 0.93A 3el0B-2fb5A:
undetectable		 3el0B-2fb5A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		5 / 10 LEU A 183
ALA A  94
VAL A 138
ILE A 126
ILE A  96
 None
 0.93A 3em3B-2fb5A:
undetectable		 3em3B-2fb5A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		6 / 12 LEU A 183
ALA A  94
VAL A 138
ILE A 126
VAL A  98
ILE A  96
 None
 1.44A 3em6B-2fb5A:
undetectable		 3em6B-2fb5A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A 154
THR A 155
GLY A 198
ALA A 195
 None
 0.82A 3jusB-2fb5A:
undetectable		 3jusB-2fb5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		3 / 3 THR A 202
SER A 193
ARG A 191
 None
 0.78A 3phnA-2fb5A:
undetectable		 3phnA-2fb5A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		5 / 12 LEU A 118
THR A 192
LEU A 181
VAL A  98
ILE A  66
 None
 1.14A 3sp9A-2fb5A:
undetectable		 3sp9A-2fb5A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		4 / 8 ILE A 108
SER A 175
THR A 166
LEU A  95
 None
 0.85A 3ua5A-2fb5A:
2.2		 3ua5A-2fb5A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		4 / 8 ILE A 151
SER A 175
THR A 166
LEU A  95
 None
 0.81A 3ua5A-2fb5A:
2.2		 3ua5A-2fb5A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		4 / 4 ASN A 150
ALA A 149
GLY A 111
THR A 112
 None
 1.17A 4bboC-2fb5A:
undetectable		 4bboC-2fb5A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		5 / 12 LEU A 183
ALA A  94
VAL A 138
ILE A 126
ILE A  96
 None
 0.92A 4dqbA-2fb5A:
undetectable		 4dqbA-2fb5A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		6 / 12 LEU A 183
ALA A  94
VAL A 138
ILE A 126
VAL A  98
ILE A  96
 None
 1.42A 4dqfA-2fb5A:
undetectable		 4dqfA-2fb5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		4 / 5 PHE A 194
TYR A  69
THR A  63
ILE A 203
 None
 1.03A 4jx1E-2fb5A:
undetectable		 4jx1E-2fb5A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		5 / 11 LEU A 183
ALA A  94
VAL A 138
ILE A 126
ILE A  96
 None
 0.97A 4rvjA-2fb5A:
undetectable		 4rvjA-2fb5A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		5 / 11 LEU A 183
ALA A  94
VAL A 138
ILE A 126
ILE A  96
 None
 0.97A 4rvjC-2fb5A:
undetectable		 4rvjC-2fb5A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 2fb5 HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Bacillus
cereus) 		3 / 3 GLY A 165
LEU A 164
HIS A 168
 None
 0.67A 5u63B-2fb5A:
undetectable		 5u63B-2fb5A:
20.37