SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fbi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2fbi PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  69
ALA A  55
GLN A  53
MET A  49
LEU A  72
 None
 1.15A 2jn3A-2fbiA:
undetectable		 2jn3A-2fbiA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 2fbi PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 LEU A  54
MET A  49
ASP A  75
 None
 0.76A 4j7xB-2fbiA:
undetectable		 4j7xB-2fbiA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fbi PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		4 / 7 ARG A  62
MET A  65
THR A  66
LEU A  69
 None
 0.85A 5b1aA-2fbiA:
undetectable
5b1aJ-2fbiA:
undetectable		 5b1aA-2fbiA:
13.47
5b1aJ-2fbiA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fbi PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		4 / 7 ARG A  62
MET A  65
THR A  66
LEU A  69
 None
 0.89A 5b3sA-2fbiA:
undetectable
5b3sJ-2fbiA:
undetectable		 5b3sA-2fbiA:
13.47
5b3sJ-2fbiA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 2fbi PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 ASP A  86
LEU A  54
LEU A  69
THR A  66
ARG A  88
 None
 1.35A 5hnxB-2fbiA:
undetectable		 5hnxB-2fbiA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fbi PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  62
MET A  65
THR A  66
LEU A  69
 None
 0.93A 5z86J-2fbiA:
undetectable		 5z86J-2fbiA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fbi PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		4 / 7 ARG A  62
MET A  65
THR A  66
LEU A  69
 None
 0.86A 5zcpA-2fbiA:
undetectable
5zcpJ-2fbiA:
undetectable		 5zcpA-2fbiA:
13.47
5zcpJ-2fbiA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fbi PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		4 / 7 ARG A  62
MET A  65
THR A  66
LEU A  69
 None
 0.88A 5zcqA-2fbiA:
undetectable
5zcqJ-2fbiA:
undetectable		 5zcqA-2fbiA:
13.47
5zcqJ-2fbiA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fbi PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  62
MET A  65
THR A  66
LEU A  69
 None
 0.93A 6nknW-2fbiA:
undetectable		 6nknW-2fbiA:
14.08