SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fbl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PGR_A_DCFA501_2 (ADENOSINE DEAMINASE)	2fbl	HYPOTHETICAL PROTEIN NE1496 (Nitrosomonas europaea)	3 / 3	LEU A 91 LEU A 18 PHE A 131	None	0.72A	2pgrA-2fblA: undetectable	2pgrA-2fblA: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YIA_B_IMNB401_2 (THYROXINE-BINDING GLOBULIN)	2fbl	HYPOTHETICAL PROTEIN NE1496 (Nitrosomonas europaea)	3 / 3	LEU A 39 ARG A 81 ARG A 24	None	0.94A	4yiaB-2fblA: undetectable	4yiaB-2fblA: 12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AOX_C_ACTC1001_0 (ALU JO CONSENSUS RNA SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN)	2fbl	HYPOTHETICAL PROTEIN NE1496 (Nitrosomonas europaea)	3 / 3	TYR A 27 THR A 77 THR A 29	None	0.56A	5aoxB-2fblA: undetectable	5aoxB-2fblA: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AOX_F_ACTF1001_0 (ALU JO CONSENSUS RNA SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN)	2fbl	HYPOTHETICAL PROTEIN NE1496 (Nitrosomonas europaea)	3 / 3	TYR A 27 THR A 77 THR A 29	None	0.55A	5aoxE-2fblA: undetectable	5aoxE-2fblA: 23.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2PGR_A_DCFA501_2","ADENOSINE DEAMINASE","2fbl","HYPOTHETICAL PROTEIN NE1496","Nitrosomonas europaea",3,"LEU A  91;LEU A  18;PHE A 131","None","0.72A","2pgrA-2fblA:undetectable","2pgrA-2fblA:18.11"],["4YIA_B_IMNB401_2","THYROXINE-BINDING GLOBULIN","2fbl","HYPOTHETICAL PROTEIN NE1496","Nitrosomonas europaea",3,"LEU A  39;ARG A  81;ARG A  24","None","0.94A","4yiaB-2fblA:undetectable","4yiaB-2fblA:12.24"],["5AOX_C_ACTC1001_0","ALU JO CONSENSUS RNA;SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN","2fbl","HYPOTHETICAL PROTEIN NE1496","Nitrosomonas europaea",3,"TYR A  27;THR A  77;THR A  29","None","0.56A","5aoxB-2fblA:undetectable","5aoxB-2fblA:23.38"],["5AOX_F_ACTF1001_0","ALU JO CONSENSUS RNA;SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN","2fbl","HYPOTHETICAL PROTEIN NE1496","Nitrosomonas europaea",3,"TYR A  27;THR A  77;THR A  29","None","0.55A","5aoxE-2fblA:undetectable","5aoxE-2fblA:23.38"]]