SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2fc9 NCL PROTEIN
(Homo
sapiens) 		4 / 8 ILE A  58
PHE A  36
ARG A  84
LEU A  23
 None
 0.90A 2eilN-2fc9A:
undetectable
2eilW-2fc9A:
undetectable		 2eilN-2fc9A:
10.27
2eilW-2fc9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2fc9 NCL PROTEIN
(Homo
sapiens) 		4 / 8 ILE A  58
PHE A  36
ARG A  84
LEU A  23
 None
 0.89A 2einA-2fc9A:
undetectable
2einJ-2fc9A:
undetectable		 2einA-2fc9A:
10.27
2einJ-2fc9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2fc9 NCL PROTEIN
(Homo
sapiens) 		4 / 8 ILE A  58
PHE A  36
ARG A  84
LEU A  23
 None
 0.87A 3ablN-2fc9A:
undetectable
3ablW-2fc9A:
undetectable		 3ablN-2fc9A:
10.27
3ablW-2fc9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2fc9 NCL PROTEIN
(Homo
sapiens) 		4 / 8 ILE A  58
PHE A  36
ARG A  84
LEU A  23
 None
 0.84A 3ag3N-2fc9A:
undetectable
3ag3W-2fc9A:
undetectable		 3ag3N-2fc9A:
10.27
3ag3W-2fc9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 2fc9 NCL PROTEIN
(Homo
sapiens) 		4 / 4 VAL A  44
THR A  28
GLU A  29
GLU A  30
 None
 1.22A 4l78A-2fc9A:
2.2		 4l78A-2fc9A:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2fc9 NCL PROTEIN
(Homo
sapiens) 		3 / 3 TYR A  25
ARG A  81
SER A  24
 None
 1.05A 4lf7I-2fc9A:
undetectable
4lf7J-2fc9A:
undetectable		 4lf7I-2fc9A:
19.70
4lf7J-2fc9A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2fc9 NCL PROTEIN
(Homo
sapiens) 		3 / 3 TYR A  25
ARG A  81
SER A  24
 None
 1.05A 4lf8I-2fc9A:
undetectable
4lf8J-2fc9A:
undetectable		 4lf8I-2fc9A:
19.70
4lf8J-2fc9A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fc9 NCL PROTEIN
(Homo
sapiens) 		4 / 7 ILE A  58
PHE A  36
ARG A  84
LEU A  23
 None
 0.84A 5iy5N-2fc9A:
undetectable
5iy5W-2fc9A:
undetectable		 5iy5N-2fc9A:
10.27
5iy5W-2fc9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 2fc9 NCL PROTEIN
(Homo
sapiens) 		4 / 8 ILE A  78
LEU A  20
LEU A  70
ALA A  69
 None
 0.81A 5y7pE-2fc9A:
undetectable		 5y7pE-2fc9A:
15.22