SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fe5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2fe5 PRESYNAPTIC PROTEIN
SAP102
(Homo
sapiens) 		4 / 8 SER A 239
ILE A 274
GLY A 275
GLY A 242
 None
 0.71A 1me7A-2fe5A:
undetectable		 1me7A-2fe5A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2fe5 PRESYNAPTIC PROTEIN
SAP102
(Homo
sapiens) 		4 / 6 GLY A 263
GLY A 264
GLU A 262
ILE A 260
 None
 0.96A 4fglD-2fe5A:
undetectable		 4fglD-2fe5A:
14.16