SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fff'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AO8_A_MTXA170_1
(DIHYDROFOLATE
REDUCTASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 ALA B 471
LEU B 619
SER B 755
LEU B 719
ALA B 758
 None
 1.05A 1ao8A-2fffB:
undetectable		 1ao8A-2fffB:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 1c9sA-2fffB:
undetectable
1c9sK-2fffB:
undetectable		 1c9sA-2fffB:
11.03
1c9sK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 1c9sA-2fffB:
undetectable
1c9sB-2fffB:
undetectable		 1c9sA-2fffB:
11.03
1c9sB-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.13A 1c9sB-2fffB:
undetectable
1c9sC-2fffB:
undetectable		 1c9sB-2fffB:
11.03
1c9sC-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 1c9sC-2fffB:
undetectable
1c9sD-2fffB:
undetectable		 1c9sC-2fffB:
11.03
1c9sD-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 1c9sD-2fffB:
undetectable
1c9sE-2fffB:
undetectable		 1c9sD-2fffB:
11.03
1c9sE-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1c9sE-2fffB:
undetectable
1c9sF-2fffB:
undetectable		 1c9sE-2fffB:
11.03
1c9sF-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1c9sF-2fffB:
undetectable
1c9sG-2fffB:
undetectable		 1c9sF-2fffB:
11.03
1c9sG-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 1c9sG-2fffB:
undetectable
1c9sH-2fffB:
undetectable		 1c9sG-2fffB:
11.03
1c9sH-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1c9sH-2fffB:
undetectable
1c9sI-2fffB:
undetectable		 1c9sH-2fffB:
11.03
1c9sI-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 1c9sJ-2fffB:
undetectable
1c9sK-2fffB:
undetectable		 1c9sJ-2fffB:
11.03
1c9sK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.06A 1c9sL-2fffB:
undetectable
1c9sM-2fffB:
undetectable		 1c9sL-2fffB:
11.03
1c9sM-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.07A 1c9sM-2fffB:
undetectable
1c9sN-2fffB:
undetectable		 1c9sM-2fffB:
11.03
1c9sN-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.06A 1c9sN-2fffB:
undetectable
1c9sO-2fffB:
undetectable		 1c9sN-2fffB:
11.03
1c9sO-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.06A 1c9sO-2fffB:
undetectable
1c9sP-2fffB:
undetectable		 1c9sO-2fffB:
11.03
1c9sP-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.06A 1c9sP-2fffB:
undetectable
1c9sQ-2fffB:
undetectable		 1c9sP-2fffB:
11.03
1c9sQ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 1c9sQ-2fffB:
undetectable
1c9sR-2fffB:
undetectable		 1c9sQ-2fffB:
11.03
1c9sR-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.06A 1c9sS-2fffB:
undetectable
1c9sT-2fffB:
undetectable		 1c9sS-2fffB:
11.03
1c9sT-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 7 GLY B 677
ALA B 688
THR B 417
HIS B 682
 None
None
None
NI  B 901 (-2.8A)
 0.88A 1c9sT-2fffB:
undetectable
1c9sU-2fffB:
undetectable		 1c9sT-2fffB:
11.03
1c9sU-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.07A 1c9sL-2fffB:
undetectable
1c9sV-2fffB:
undetectable		 1c9sL-2fffB:
11.03
1c9sV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 ALA B 459
SER B 460
LYS B 463
SER B 516
ASN B 518
LYS B 651
GLY B 653
 None
 0.39A 1ghmA-2fffB:
16.0		 1ghmA-2fffB:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1gtfA-2fffB:
undetectable
1gtfK-2fffB:
undetectable		 1gtfA-2fffB:
11.03
1gtfK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1gtfA-2fffB:
undetectable
1gtfB-2fffB:
undetectable		 1gtfA-2fffB:
11.03
1gtfB-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 1gtfB-2fffB:
undetectable
1gtfC-2fffB:
undetectable		 1gtfB-2fffB:
11.03
1gtfC-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1gtfC-2fffB:
undetectable
1gtfD-2fffB:
undetectable		 1gtfC-2fffB:
11.03
1gtfD-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.00A 1gtfD-2fffB:
undetectable
1gtfE-2fffB:
undetectable		 1gtfD-2fffB:
11.03
1gtfE-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 1gtfE-2fffB:
undetectable
1gtfF-2fffB:
undetectable		 1gtfE-2fffB:
11.03
1gtfF-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1gtfF-2fffB:
undetectable
1gtfG-2fffB:
undetectable		 1gtfF-2fffB:
11.03
1gtfG-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1gtfG-2fffB:
undetectable
1gtfH-2fffB:
undetectable		 1gtfG-2fffB:
11.03
1gtfH-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1gtfH-2fffB:
undetectable
1gtfI-2fffB:
undetectable		 1gtfH-2fffB:
11.03
1gtfI-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 1gtfI-2fffB:
undetectable
1gtfJ-2fffB:
undetectable		 1gtfI-2fffB:
11.03
1gtfJ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1gtfJ-2fffB:
undetectable
1gtfK-2fffB:
undetectable		 1gtfJ-2fffB:
11.03
1gtfK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 7 GLY B 677
ALA B 688
THR B 417
HIS B 682
 None
None
None
NI  B 901 (-2.8A)
 0.90A 1gtfL-2fffB:
undetectable
1gtfM-2fffB:
undetectable		 1gtfL-2fffB:
11.03
1gtfM-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 1gtfO-2fffB:
undetectable
1gtfP-2fffB:
undetectable		 1gtfO-2fffB:
11.03
1gtfP-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.05A 1gtfP-2fffB:
undetectable
1gtfQ-2fffB:
undetectable		 1gtfP-2fffB:
11.03
1gtfQ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 1gtfQ-2fffB:
undetectable
1gtfR-2fffB:
undetectable		 1gtfQ-2fffB:
11.03
1gtfR-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 1gtfR-2fffB:
undetectable
1gtfS-2fffB:
undetectable		 1gtfR-2fffB:
11.03
1gtfS-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 1gtfS-2fffB:
undetectable
1gtfT-2fffB:
undetectable		 1gtfS-2fffB:
11.03
1gtfT-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.00A 1gtfT-2fffB:
undetectable
1gtfU-2fffB:
undetectable		 1gtfT-2fffB:
11.03
1gtfU-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 1gtfU-2fffB:
undetectable
1gtfV-2fffB:
undetectable		 1gtfU-2fffB:
11.03
1gtfV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 1gtfL-2fffB:
undetectable
1gtfV-2fffB:
undetectable		 1gtfL-2fffB:
11.03
1gtfV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 8 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 1gtnA-2fffB:
undetectable
1gtnB-2fffB:
undetectable		 1gtnA-2fffB:
11.03
1gtnB-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.06A 1gtnM-2fffB:
undetectable
1gtnN-2fffB:
undetectable		 1gtnM-2fffB:
11.03
1gtnN-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.00A 1gtnN-2fffB:
undetectable
1gtnO-2fffB:
undetectable		 1gtnN-2fffB:
11.03
1gtnO-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.00A 1gtnR-2fffB:
undetectable
1gtnS-2fffB:
undetectable		 1gtnR-2fffB:
11.03
1gtnS-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 1gtnT-2fffB:
undetectable
1gtnU-2fffB:
undetectable		 1gtnT-2fffB:
11.03
1gtnU-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 0.99A 1gtnU-2fffB:
undetectable
1gtnV-2fffB:
undetectable		 1gtnU-2fffB:
11.03
1gtnV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		8 / 12 ALA B 459
SER B 460
LYS B 463
SER B 516
ASN B 518
THR B 629
LYS B 651
GLY B 653
 None
 0.58A 1i2wA-2fffB:
16.2		 1i2wA-2fffB:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		8 / 12 SER B 460
LYS B 463
SER B 516
ASN B 518
ASN B 656
THR B 629
LYS B 651
GLY B 653
 None
 1.09A 1i2wA-2fffB:
16.2		 1i2wA-2fffB:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 ALA B 459
SER B 460
LYS B 463
SER B 516
ASN B 518
THR B 629
GLY B 653
 None
 0.62A 1i2wB-2fffB:
16.3		 1i2wB-2fffB:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 SER B 460
LYS B 463
SER B 516
ASN B 518
ASN B 656
THR B 629
GLY B 653
 None
 1.17A 1i2wB-2fffB:
16.3		 1i2wB-2fffB:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 ILE B 482
ASN B 485
LEU B 509
GLY B 510
ALA B 521
 None
 1.36A 1ju6A-2fffB:
undetectable		 1ju6A-2fffB:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 ILE B 482
ASN B 485
LEU B 509
GLY B 510
ALA B 521
 None
 1.36A 1ju6C-2fffB:
undetectable		 1ju6C-2fffB:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 ILE B 482
ASN B 485
LEU B 509
GLY B 510
ALA B 521
 None
 1.36A 1ju6D-2fffB:
undetectable		 1ju6D-2fffB:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 GLY B 557
GLY B 558
GLY B 559
ASN B 660
TRP B 662
 None
 0.88A 1qzzA-2fffB:
undetectable		 1qzzA-2fffB:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 1utdA-2fffB:
undetectable
1utdB-2fffB:
undetectable		 1utdA-2fffB:
11.03
1utdB-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 8 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1utdB-2fffB:
undetectable
1utdC-2fffB:
undetectable		 1utdB-2fffB:
11.03
1utdC-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 1utdC-2fffB:
undetectable
1utdD-2fffB:
undetectable		 1utdC-2fffB:
11.03
1utdD-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.13A 1utdD-2fffB:
undetectable
1utdE-2fffB:
undetectable		 1utdD-2fffB:
11.03
1utdE-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 1utdE-2fffB:
undetectable
1utdF-2fffB:
undetectable		 1utdE-2fffB:
11.03
1utdF-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 8 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.14A 1utdF-2fffB:
undetectable
1utdG-2fffB:
undetectable		 1utdF-2fffB:
11.03
1utdG-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.07A 1utdG-2fffB:
undetectable
1utdH-2fffB:
undetectable		 1utdG-2fffB:
11.03
1utdH-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1utdH-2fffB:
undetectable
1utdI-2fffB:
undetectable		 1utdH-2fffB:
11.03
1utdI-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 8 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 1utdI-2fffB:
undetectable
1utdJ-2fffB:
undetectable		 1utdI-2fffB:
11.03
1utdJ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 8 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 1utdJ-2fffB:
undetectable
1utdK-2fffB:
undetectable		 1utdJ-2fffB:
11.03
1utdK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 1utdA-2fffB:
undetectable
1utdK-2fffB:
undetectable		 1utdA-2fffB:
11.03
1utdK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.00A 1utdL-2fffB:
undetectable
1utdM-2fffB:
undetectable		 1utdL-2fffB:
11.03
1utdM-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.06A 1utdM-2fffB:
undetectable
1utdN-2fffB:
undetectable		 1utdM-2fffB:
11.03
1utdN-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.06A 1utdN-2fffB:
undetectable
1utdO-2fffB:
undetectable		 1utdN-2fffB:
11.03
1utdO-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 1utdP-2fffB:
undetectable
1utdQ-2fffB:
undetectable		 1utdP-2fffB:
11.03
1utdQ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.07A 1utdQ-2fffB:
undetectable
1utdR-2fffB:
undetectable		 1utdQ-2fffB:
11.03
1utdR-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 1utdR-2fffB:
undetectable
1utdS-2fffB:
undetectable		 1utdR-2fffB:
11.03
1utdS-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 1utdS-2fffB:
undetectable
1utdT-2fffB:
undetectable		 1utdS-2fffB:
11.03
1utdT-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.01A 1utdT-2fffB:
undetectable
1utdU-2fffB:
undetectable		 1utdT-2fffB:
11.03
1utdU-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 1utdU-2fffB:
undetectable
1utdV-2fffB:
undetectable		 1utdU-2fffB:
11.03
1utdV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 1utdL-2fffB:
undetectable
1utdV-2fffB:
undetectable		 1utdL-2fffB:
11.03
1utdV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 GLY B 557
GLY B 558
GLY B 559
ASN B 660
TRP B 662
 None
 0.91A 1xdsA-2fffB:
undetectable		 1xdsA-2fffB:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 GLY B 557
GLY B 558
GLY B 559
ASN B 660
TRP B 662
 None
 0.84A 1xdsB-2fffB:
undetectable		 1xdsB-2fffB:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 SER B 460
LYS B 463
SER B 516
ASN B 518
THR B 629
LYS B 651
GLY B 653
 None
 0.64A 1ymxA-2fffB:
16.9		 1ymxA-2fffB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 SER B 460
LYS B 463
SER B 516
ASN B 518
LYS B 651
GLY B 653
 None
 0.45A 1ymxB-2fffB:
17.0		 1ymxB-2fffB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 ALA B 467
THR B 524
MET B 616
GLY B 618
LEU B 620
 None
 1.08A 2hw2A-2fffB:
undetectable		 2hw2A-2fffB:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 LEU B 476
MET B 477
ILE B 772
GLY B 469
LEU B 466
 None
 0.99A 2lbdA-2fffB:
undetectable		 2lbdA-2fffB:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB4_0
(FERROCHELATASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 6 MET B 539
ARG B 529
PRO B 458
GLY B 558
 None
 1.30A 3aqiB-2fffB:
0.0		 3aqiB-2fffB:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 7 HIS B 567
LEU B 620
TYR B 608
ILE B 470
 None
 0.97A 3avpA-2fffB:
undetectable		 3avpA-2fffB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		3 / 3 TRP B 648
VAL B 564
ARG B 456
 None
 0.98A 3b0wA-2fffB:
undetectable		 3b0wA-2fffB:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		3 / 3 TRP B 712
VAL B 422
ARG B 419
 None
 0.80A 3b0wA-2fffB:
undetectable		 3b0wA-2fffB:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 7 ILE B 470
GLN B 474
GLY B 469
LEU B 509
 None
 0.70A 3bjwB-2fffB:
undetectable		 3bjwB-2fffB:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 7 ILE B 470
GLN B 474
GLY B 469
LEU B 509
 None
 0.69A 3bjwF-2fffB:
undetectable		 3bjwF-2fffB:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 7 ILE B 470
GLN B 474
GLY B 469
LEU B 509
 None
 0.72A 3bjwH-2fffB:
undetectable		 3bjwH-2fffB:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 LYS B 463
TYR B 498
SER B 516
ASN B 518
THR B 629
LYS B 651
GLY B 653
 None
 0.65A 3hlwA-2fffB:
16.7		 3hlwA-2fffB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 TYR B 498
SER B 516
ASN B 518
THR B 629
LYS B 651
THR B 652
GLY B 653
 None
 0.58A 3hlwB-2fffB:
16.9		 3hlwB-2fffB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 LYS B 463
ASN B 518
LYS B 651
THR B 652
GLY B 653
 None
 0.40A 3huoA-2fffB:
16.9		 3huoA-2fffB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 ALA B 459
SER B 460
LYS B 463
ASN B 518
THR B 652
GLY B 653
 None
 0.57A 3mzeA-2fffB:
13.5		 3mzeA-2fffB:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 ALA B 459
SER B 460
LYS B 463
THR B 652
GLY B 653
THR B 655
 None
 0.73A 3mzeA-2fffB:
13.5		 3mzeA-2fffB:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 SER B 460
SER B 516
THR B 629
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.64A 3ny4A-2fffB:
16.2		 3ny4A-2fffB:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 LYS B 463
SER B 516
ASN B 518
LYS B 651
GLY B 653
 None
 0.40A 3q07A-2fffB:
17.0		 3q07A-2fffB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 LYS B 463
SER B 516
ASN B 518
LYS B 651
GLY B 653
 None
 0.57A 3q07B-2fffB:
10.8		 3q07B-2fffB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 7 LEU B 466
GLU B 540
PRO B 547
ILE B 546
 None
 0.89A 3s56B-2fffB:
undetectable		 3s56B-2fffB:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		8 / 12 ALA B 459
SER B 460
TYR B 498
SER B 516
ASN B 518
LYS B 651
THR B 652
GLY B 653
 None
 0.47A 3sh8A-2fffB:
16.7		 3sh8A-2fffB:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 ALA B 459
SER B 460
LYS B 463
SER B 516
ASN B 518
LYS B 651
GLY B 653
 None
 0.39A 3sh8B-2fffB:
16.4		 3sh8B-2fffB:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 LYS B 463
SER B 516
ASN B 518
THR B 629
LYS B 651
THR B 652
GLY B 653
 None
 0.73A 4euzA-2fffB:
16.6		 4euzA-2fffB:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 LYS B 463
SER B 516
THR B 629
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.73A 4euzA-2fffB:
16.6		 4euzA-2fffB:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 7 GLY B 505
TYR B 486
ASN B 781
GLU B 511
 None
 1.01A 4fgkB-2fffB:
undetectable		 4fgkB-2fffB:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 10 TYR B 498
SER B 516
ASN B 518
LYS B 651
THR B 652
GLY B 653
 None
 0.56A 4fh2A-2fffB:
17.3		 4fh2A-2fffB:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 7 GLN B 780
ASN B 781
ILE B 786
TRP B 783
 None
 1.20A 4ii8A-2fffB:
undetectable		 4ii8A-2fffB:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		8 / 12 ALA B 459
SER B 460
TYR B 498
SER B 516
ASN B 518
LYS B 651
THR B 652
GLY B 653
 None
 0.41A 4n9kA-2fffB:
16.2		 4n9kA-2fffB:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 ALA B 459
SER B 460
SER B 516
ASN B 518
LYS B 651
THR B 652
GLY B 653
 None
 0.35A 4n9kB-2fffB:
16.5		 4n9kB-2fffB:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		3 / 3 ASP B 337
ASN B 449
SER B 400
 None
 0.69A 4obwA-2fffB:
undetectable		 4obwA-2fffB:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		3 / 3 ASP B 337
ASN B 449
SER B 404
 None
 0.79A 4obwA-2fffB:
undetectable		 4obwA-2fffB:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 ALA B 471
GLY B 469
MET B 616
ASN B 759
GLY B 475
 None
 1.26A 4obwD-2fffB:
undetectable		 4obwD-2fffB:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 TYR B 498
ASN B 518
THR B 629
LYS B 651
THR B 652
GLY B 653
 None
 0.60A 4pm5A-2fffB:
17.0		 4pm5A-2fffB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 TYR B 498
SER B 516
ASN B 518
LYS B 651
THR B 652
GLY B 653
 None
 0.74A 4pm5A-2fffB:
17.0		 4pm5A-2fffB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 LYS B 463
TYR B 498
ASN B 518
THR B 629
LYS B 651
GLY B 653
 None
 0.69A 4pm7A-2fffB:
16.9		 4pm7A-2fffB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 LYS B 463
TYR B 498
SER B 516
ASN B 518
LYS B 651
GLY B 653
 None
 0.79A 4pm7A-2fffB:
16.9		 4pm7A-2fffB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 TYR B 498
ASN B 518
THR B 629
LYS B 651
THR B 652
GLY B 653
 None
 0.58A 4pm9A-2fffB:
17.0		 4pm9A-2fffB:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 TYR B 498
SER B 516
ASN B 518
LYS B 651
THR B 652
GLY B 653
 None
 0.71A 4pm9A-2fffB:
17.0		 4pm9A-2fffB:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		3 / 3 LEU B 620
ASP B 647
ILE B 472
 None
 0.72A 4xi3D-2fffB:
undetectable		 4xi3D-2fffB:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 LEU B 509
ALA B 512
GLU B 511
MET B 506
GLY B 773
 None
 1.38A 5dxbA-2fffB:
undetectable		 5dxbA-2fffB:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eeuA-2fffB:
undetectable
5eeuB-2fffB:
undetectable		 5eeuA-2fffB:
11.03
5eeuB-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eeuB-2fffB:
undetectable
5eeuC-2fffB:
undetectable		 5eeuB-2fffB:
11.03
5eeuC-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 5eeuC-2fffB:
undetectable
5eeuD-2fffB:
undetectable		 5eeuC-2fffB:
11.03
5eeuD-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eeuD-2fffB:
undetectable
5eeuE-2fffB:
undetectable		 5eeuD-2fffB:
11.03
5eeuE-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5eeuE-2fffB:
undetectable
5eeuF-2fffB:
undetectable		 5eeuE-2fffB:
11.03
5eeuF-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eeuF-2fffB:
undetectable
5eeuG-2fffB:
undetectable		 5eeuF-2fffB:
11.03
5eeuG-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eeuG-2fffB:
undetectable
5eeuH-2fffB:
undetectable		 5eeuG-2fffB:
11.03
5eeuH-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eeuH-2fffB:
undetectable
5eeuI-2fffB:
undetectable		 5eeuH-2fffB:
11.03
5eeuI-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5eeuI-2fffB:
undetectable
5eeuJ-2fffB:
undetectable		 5eeuI-2fffB:
11.03
5eeuJ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eeuJ-2fffB:
undetectable
5eeuK-2fffB:
undetectable		 5eeuJ-2fffB:
11.03
5eeuK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eeuA-2fffB:
undetectable
5eeuK-2fffB:
undetectable		 5eeuA-2fffB:
11.03
5eeuK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eeuN-2fffB:
undetectable
5eeuO-2fffB:
undetectable		 5eeuN-2fffB:
11.03
5eeuO-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eeuO-2fffB:
undetectable
5eeuP-2fffB:
undetectable		 5eeuO-2fffB:
11.03
5eeuP-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5eeuP-2fffB:
undetectable
5eeuQ-2fffB:
undetectable		 5eeuP-2fffB:
11.03
5eeuQ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eeuQ-2fffB:
undetectable
5eeuR-2fffB:
undetectable		 5eeuQ-2fffB:
11.03
5eeuR-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5eeuR-2fffB:
undetectable
5eeuS-2fffB:
undetectable		 5eeuR-2fffB:
11.03
5eeuS-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.07A 5eeuS-2fffB:
undetectable
5eeuT-2fffB:
undetectable		 5eeuS-2fffB:
11.03
5eeuT-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eeuT-2fffB:
undetectable
5eeuU-2fffB:
undetectable		 5eeuT-2fffB:
11.03
5eeuU-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.05A 5eeuU-2fffB:
undetectable
5eeuV-2fffB:
undetectable		 5eeuU-2fffB:
11.03
5eeuV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eevA-2fffB:
undetectable
5eevB-2fffB:
undetectable		 5eevA-2fffB:
11.03
5eevB-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eevB-2fffB:
undetectable
5eevC-2fffB:
undetectable		 5eevB-2fffB:
11.03
5eevC-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 5eevC-2fffB:
undetectable
5eevD-2fffB:
undetectable		 5eevC-2fffB:
11.03
5eevD-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eevD-2fffB:
undetectable
5eevE-2fffB:
undetectable		 5eevD-2fffB:
11.03
5eevE-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5eevE-2fffB:
undetectable
5eevF-2fffB:
undetectable		 5eevE-2fffB:
11.03
5eevF-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eevF-2fffB:
undetectable
5eevG-2fffB:
undetectable		 5eevF-2fffB:
11.03
5eevG-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eevG-2fffB:
undetectable
5eevH-2fffB:
undetectable		 5eevG-2fffB:
11.03
5eevH-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eevH-2fffB:
undetectable
5eevI-2fffB:
undetectable		 5eevH-2fffB:
11.03
5eevI-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5eevI-2fffB:
undetectable
5eevJ-2fffB:
undetectable		 5eevI-2fffB:
11.03
5eevJ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eevJ-2fffB:
undetectable
5eevK-2fffB:
undetectable		 5eevJ-2fffB:
11.03
5eevK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eevA-2fffB:
undetectable
5eevK-2fffB:
undetectable		 5eevA-2fffB:
11.03
5eevK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 8 GLY B 677
ALA B 688
THR B 417
HIS B 682
 None
None
None
NI  B 901 (-2.8A)
 0.87A 5eevL-2fffB:
undetectable
5eevV-2fffB:
undetectable		 5eevL-2fffB:
11.03
5eevV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eevN-2fffB:
undetectable
5eevO-2fffB:
undetectable		 5eevN-2fffB:
11.03
5eevO-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eevO-2fffB:
undetectable
5eevP-2fffB:
undetectable		 5eevO-2fffB:
11.03
5eevP-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5eevP-2fffB:
undetectable
5eevQ-2fffB:
undetectable		 5eevP-2fffB:
11.03
5eevQ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eevQ-2fffB:
undetectable
5eevR-2fffB:
undetectable		 5eevQ-2fffB:
11.03
5eevR-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5eevR-2fffB:
undetectable
5eevS-2fffB:
undetectable		 5eevR-2fffB:
11.03
5eevS-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eevS-2fffB:
undetectable
5eevT-2fffB:
undetectable		 5eevS-2fffB:
11.03
5eevT-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eevT-2fffB:
undetectable
5eevU-2fffB:
undetectable		 5eevT-2fffB:
11.03
5eevU-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.05A 5eevU-2fffB:
undetectable
5eevV-2fffB:
undetectable		 5eevU-2fffB:
11.03
5eevV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eewA-2fffB:
undetectable
5eewB-2fffB:
undetectable		 5eewA-2fffB:
11.03
5eewB-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eewB-2fffB:
undetectable
5eewC-2fffB:
undetectable		 5eewB-2fffB:
11.03
5eewC-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 5eewC-2fffB:
undetectable
5eewD-2fffB:
undetectable		 5eewC-2fffB:
11.03
5eewD-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eewD-2fffB:
undetectable
5eewE-2fffB:
undetectable		 5eewD-2fffB:
11.03
5eewE-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5eewE-2fffB:
undetectable
5eewF-2fffB:
undetectable		 5eewE-2fffB:
11.03
5eewF-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eewF-2fffB:
undetectable
5eewG-2fffB:
undetectable		 5eewF-2fffB:
11.03
5eewG-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eewG-2fffB:
undetectable
5eewH-2fffB:
undetectable		 5eewG-2fffB:
11.03
5eewH-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eewH-2fffB:
undetectable
5eewI-2fffB:
undetectable		 5eewH-2fffB:
11.03
5eewI-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5eewI-2fffB:
undetectable
5eewJ-2fffB:
undetectable		 5eewI-2fffB:
11.03
5eewJ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eewJ-2fffB:
undetectable
5eewK-2fffB:
undetectable		 5eewJ-2fffB:
11.03
5eewK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eewA-2fffB:
undetectable
5eewK-2fffB:
undetectable		 5eewA-2fffB:
11.03
5eewK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 8 GLY B 677
ALA B 688
THR B 417
HIS B 682
 None
None
None
NI  B 901 (-2.8A)
 0.88A 5eewL-2fffB:
undetectable
5eewV-2fffB:
undetectable		 5eewL-2fffB:
11.03
5eewV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eewN-2fffB:
undetectable
5eewO-2fffB:
undetectable		 5eewN-2fffB:
11.03
5eewO-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eewO-2fffB:
undetectable
5eewP-2fffB:
undetectable		 5eewO-2fffB:
11.03
5eewP-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5eewP-2fffB:
undetectable
5eewQ-2fffB:
undetectable		 5eewP-2fffB:
11.03
5eewQ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eewQ-2fffB:
undetectable
5eewR-2fffB:
undetectable		 5eewQ-2fffB:
11.03
5eewR-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5eewR-2fffB:
undetectable
5eewS-2fffB:
undetectable		 5eewR-2fffB:
11.03
5eewS-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eewS-2fffB:
undetectable
5eewT-2fffB:
undetectable		 5eewS-2fffB:
11.03
5eewT-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eewT-2fffB:
undetectable
5eewU-2fffB:
undetectable		 5eewT-2fffB:
11.03
5eewU-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.05A 5eewU-2fffB:
undetectable
5eewV-2fffB:
undetectable		 5eewU-2fffB:
11.03
5eewV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eexA-2fffB:
undetectable
5eexB-2fffB:
undetectable		 5eexA-2fffB:
11.03
5eexB-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eexB-2fffB:
undetectable
5eexC-2fffB:
undetectable		 5eexB-2fffB:
11.03
5eexC-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 5eexC-2fffB:
undetectable
5eexD-2fffB:
undetectable		 5eexC-2fffB:
11.03
5eexD-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eexD-2fffB:
undetectable
5eexE-2fffB:
undetectable		 5eexD-2fffB:
11.03
5eexE-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5eexE-2fffB:
undetectable
5eexF-2fffB:
undetectable		 5eexE-2fffB:
11.03
5eexF-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eexF-2fffB:
undetectable
5eexG-2fffB:
undetectable		 5eexF-2fffB:
11.03
5eexG-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eexG-2fffB:
undetectable
5eexH-2fffB:
undetectable		 5eexG-2fffB:
11.03
5eexH-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eexH-2fffB:
undetectable
5eexI-2fffB:
undetectable		 5eexH-2fffB:
11.03
5eexI-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5eexI-2fffB:
undetectable
5eexJ-2fffB:
undetectable		 5eexI-2fffB:
11.03
5eexJ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eexJ-2fffB:
undetectable
5eexK-2fffB:
undetectable		 5eexJ-2fffB:
11.03
5eexK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eexA-2fffB:
undetectable
5eexK-2fffB:
undetectable		 5eexA-2fffB:
11.03
5eexK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eexN-2fffB:
undetectable
5eexO-2fffB:
undetectable		 5eexN-2fffB:
11.03
5eexO-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eexO-2fffB:
undetectable
5eexP-2fffB:
undetectable		 5eexO-2fffB:
11.03
5eexP-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5eexP-2fffB:
undetectable
5eexQ-2fffB:
undetectable		 5eexP-2fffB:
11.03
5eexQ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eexQ-2fffB:
undetectable
5eexR-2fffB:
undetectable		 5eexQ-2fffB:
11.03
5eexR-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5eexR-2fffB:
undetectable
5eexS-2fffB:
undetectable		 5eexR-2fffB:
11.03
5eexS-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eexS-2fffB:
undetectable
5eexT-2fffB:
undetectable		 5eexS-2fffB:
11.03
5eexT-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eexT-2fffB:
undetectable
5eexU-2fffB:
undetectable		 5eexT-2fffB:
11.03
5eexU-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.05A 5eexU-2fffB:
undetectable
5eexV-2fffB:
undetectable		 5eexU-2fffB:
11.03
5eexV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eeyA-2fffB:
undetectable
5eeyB-2fffB:
undetectable		 5eeyA-2fffB:
11.03
5eeyB-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eeyB-2fffB:
undetectable
5eeyC-2fffB:
undetectable		 5eeyB-2fffB:
11.03
5eeyC-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 5eeyC-2fffB:
undetectable
5eeyD-2fffB:
undetectable		 5eeyC-2fffB:
11.03
5eeyD-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eeyD-2fffB:
undetectable
5eeyE-2fffB:
undetectable		 5eeyD-2fffB:
11.03
5eeyE-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5eeyE-2fffB:
undetectable
5eeyF-2fffB:
undetectable		 5eeyE-2fffB:
11.03
5eeyF-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eeyF-2fffB:
undetectable
5eeyG-2fffB:
undetectable		 5eeyF-2fffB:
11.03
5eeyG-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eeyG-2fffB:
undetectable
5eeyH-2fffB:
undetectable		 5eeyG-2fffB:
11.03
5eeyH-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eeyH-2fffB:
undetectable
5eeyI-2fffB:
undetectable		 5eeyH-2fffB:
11.03
5eeyI-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5eeyI-2fffB:
undetectable
5eeyJ-2fffB:
undetectable		 5eeyI-2fffB:
11.03
5eeyJ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eeyJ-2fffB:
undetectable
5eeyK-2fffB:
undetectable		 5eeyJ-2fffB:
11.03
5eeyK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eeyA-2fffB:
undetectable
5eeyK-2fffB:
undetectable		 5eeyA-2fffB:
11.03
5eeyK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eeyN-2fffB:
undetectable
5eeyO-2fffB:
undetectable		 5eeyN-2fffB:
11.03
5eeyO-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eeyO-2fffB:
undetectable
5eeyP-2fffB:
undetectable		 5eeyO-2fffB:
11.03
5eeyP-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5eeyP-2fffB:
undetectable
5eeyQ-2fffB:
undetectable		 5eeyP-2fffB:
11.03
5eeyQ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eeyQ-2fffB:
undetectable
5eeyR-2fffB:
undetectable		 5eeyQ-2fffB:
11.03
5eeyR-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5eeyR-2fffB:
undetectable
5eeyS-2fffB:
undetectable		 5eeyR-2fffB:
11.03
5eeyS-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.07A 5eeyS-2fffB:
undetectable
5eeyT-2fffB:
undetectable		 5eeyS-2fffB:
11.03
5eeyT-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eeyT-2fffB:
undetectable
5eeyU-2fffB:
undetectable		 5eeyT-2fffB:
11.03
5eeyU-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.05A 5eeyU-2fffB:
undetectable
5eeyV-2fffB:
undetectable		 5eeyU-2fffB:
11.03
5eeyV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eezA-2fffB:
undetectable
5eezB-2fffB:
undetectable		 5eezA-2fffB:
11.03
5eezB-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eezB-2fffB:
undetectable
5eezC-2fffB:
undetectable		 5eezB-2fffB:
11.03
5eezC-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 5eezC-2fffB:
undetectable
5eezD-2fffB:
undetectable		 5eezC-2fffB:
11.03
5eezD-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eezD-2fffB:
undetectable
5eezE-2fffB:
undetectable		 5eezD-2fffB:
11.03
5eezE-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5eezE-2fffB:
undetectable
5eezF-2fffB:
undetectable		 5eezE-2fffB:
11.03
5eezF-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eezF-2fffB:
undetectable
5eezG-2fffB:
undetectable		 5eezF-2fffB:
11.03
5eezG-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eezG-2fffB:
undetectable
5eezH-2fffB:
undetectable		 5eezG-2fffB:
11.03
5eezH-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5eezH-2fffB:
undetectable
5eezI-2fffB:
undetectable		 5eezH-2fffB:
11.03
5eezI-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5eezI-2fffB:
undetectable
5eezJ-2fffB:
undetectable		 5eezI-2fffB:
11.03
5eezJ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eezJ-2fffB:
undetectable
5eezK-2fffB:
undetectable		 5eezJ-2fffB:
11.03
5eezK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5eezA-2fffB:
undetectable
5eezK-2fffB:
undetectable		 5eezA-2fffB:
11.03
5eezK-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 8 GLY B 677
ALA B 688
THR B 417
HIS B 682
 None
None
None
NI  B 901 (-2.8A)
 0.87A 5eezL-2fffB:
undetectable
5eezV-2fffB:
undetectable		 5eezL-2fffB:
11.03
5eezV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eezN-2fffB:
undetectable
5eezO-2fffB:
undetectable		 5eezN-2fffB:
11.03
5eezO-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5eezO-2fffB:
undetectable
5eezP-2fffB:
undetectable		 5eezO-2fffB:
11.03
5eezP-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5eezP-2fffB:
undetectable
5eezQ-2fffB:
undetectable		 5eezP-2fffB:
11.03
5eezQ-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eezQ-2fffB:
undetectable
5eezR-2fffB:
undetectable		 5eezQ-2fffB:
11.03
5eezR-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5eezR-2fffB:
undetectable
5eezS-2fffB:
undetectable		 5eezR-2fffB:
11.03
5eezS-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5eezS-2fffB:
undetectable
5eezT-2fffB:
undetectable		 5eezS-2fffB:
11.03
5eezT-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5eezT-2fffB:
undetectable
5eezU-2fffB:
undetectable		 5eezT-2fffB:
11.03
5eezU-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.05A 5eezU-2fffB:
undetectable
5eezV-2fffB:
undetectable		 5eezU-2fffB:
11.03
5eezV-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5ef0A-2fffB:
undetectable
5ef0B-2fffB:
undetectable		 5ef0A-2fffB:
11.03
5ef0B-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5ef0B-2fffB:
undetectable
5ef0C-2fffB:
undetectable		 5ef0B-2fffB:
11.03
5ef0C-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 5ef0C-2fffB:
undetectable
5ef0D-2fffB:
undetectable		 5ef0C-2fffB:
11.03
5ef0D-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5ef0D-2fffB:
undetectable
5ef0E-2fffB:
undetectable		 5ef0D-2fffB:
11.03
5ef0E-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5ef0E-2fffB:
undetectable
5ef0F-2fffB:
undetectable		 5ef0E-2fffB:
11.03
5ef0F-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5ef0F-2fffB:
undetectable
5ef0G-2fffB:
undetectable		 5ef0F-2fffB:
11.03
5ef0G-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5ef0G-2fffB:
undetectable
5ef0H-2fffB:
undetectable		 5ef0G-2fffB:
11.03
5ef0H-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5ef0H-2fffB:
undetectable
5ef0I-2fffB:
undetectable		 5ef0H-2fffB:
11.03
5ef0I-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5ef0I-2fffB:
undetectable
5ef0J-2fffB:
undetectable		 5ef0I-2fffB:
11.03
5ef0J-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5ef0J-2fffB:
undetectable
5ef0K-2fffB:
undetectable		 5ef0J-2fffB:
11.03
5ef0K-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5ef0A-2fffB:
undetectable
5ef0K-2fffB:
undetectable		 5ef0A-2fffB:
11.03
5ef0K-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5ef0N-2fffB:
undetectable
5ef0O-2fffB:
undetectable		 5ef0N-2fffB:
11.03
5ef0O-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5ef0O-2fffB:
undetectable
5ef0P-2fffB:
undetectable		 5ef0O-2fffB:
11.03
5ef0P-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5ef0P-2fffB:
undetectable
5ef0Q-2fffB:
undetectable		 5ef0P-2fffB:
11.03
5ef0Q-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5ef0Q-2fffB:
undetectable
5ef0R-2fffB:
undetectable		 5ef0Q-2fffB:
11.03
5ef0R-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5ef0R-2fffB:
undetectable
5ef0S-2fffB:
undetectable		 5ef0R-2fffB:
11.03
5ef0S-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5ef0S-2fffB:
undetectable
5ef0T-2fffB:
undetectable		 5ef0S-2fffB:
11.03
5ef0T-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5ef0T-2fffB:
undetectable
5ef0U-2fffB:
undetectable		 5ef0T-2fffB:
11.03
5ef0U-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.05A 5ef0U-2fffB:
undetectable
5ef0V-2fffB:
undetectable		 5ef0U-2fffB:
11.03
5ef0V-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5ef1A-2fffB:
undetectable
5ef1B-2fffB:
undetectable		 5ef1A-2fffB:
11.03
5ef1B-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5ef1B-2fffB:
undetectable
5ef1C-2fffB:
undetectable		 5ef1B-2fffB:
11.03
5ef1C-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 5ef1C-2fffB:
undetectable
5ef1D-2fffB:
undetectable		 5ef1C-2fffB:
11.03
5ef1D-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5ef1D-2fffB:
undetectable
5ef1E-2fffB:
undetectable		 5ef1D-2fffB:
11.03
5ef1E-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5ef1E-2fffB:
undetectable
5ef1F-2fffB:
undetectable		 5ef1E-2fffB:
11.03
5ef1F-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5ef1F-2fffB:
undetectable
5ef1G-2fffB:
undetectable		 5ef1F-2fffB:
11.03
5ef1G-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5ef1G-2fffB:
undetectable
5ef1H-2fffB:
undetectable		 5ef1G-2fffB:
11.03
5ef1H-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5ef1H-2fffB:
undetectable
5ef1I-2fffB:
undetectable		 5ef1H-2fffB:
11.03
5ef1I-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5ef1I-2fffB:
undetectable
5ef1J-2fffB:
undetectable		 5ef1I-2fffB:
11.03
5ef1J-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5ef1J-2fffB:
undetectable
5ef1K-2fffB:
undetectable		 5ef1J-2fffB:
11.03
5ef1K-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5ef1A-2fffB:
undetectable
5ef1K-2fffB:
undetectable		 5ef1A-2fffB:
11.03
5ef1K-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 8 GLY B 677
ALA B 688
THR B 417
HIS B 682
 None
None
None
NI  B 901 (-2.8A)
 0.88A 5ef1L-2fffB:
undetectable
5ef1V-2fffB:
undetectable		 5ef1L-2fffB:
11.03
5ef1V-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5ef1N-2fffB:
undetectable
5ef1O-2fffB:
undetectable		 5ef1N-2fffB:
11.03
5ef1O-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5ef1O-2fffB:
undetectable
5ef1P-2fffB:
undetectable		 5ef1O-2fffB:
11.03
5ef1P-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5ef1P-2fffB:
undetectable
5ef1Q-2fffB:
undetectable		 5ef1P-2fffB:
11.03
5ef1Q-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5ef1Q-2fffB:
undetectable
5ef1R-2fffB:
undetectable		 5ef1Q-2fffB:
11.03
5ef1R-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5ef1R-2fffB:
undetectable
5ef1S-2fffB:
undetectable		 5ef1R-2fffB:
11.03
5ef1S-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5ef1S-2fffB:
undetectable
5ef1T-2fffB:
undetectable		 5ef1S-2fffB:
11.03
5ef1T-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5ef1T-2fffB:
undetectable
5ef1U-2fffB:
undetectable		 5ef1T-2fffB:
11.03
5ef1U-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.05A 5ef1U-2fffB:
undetectable
5ef1V-2fffB:
undetectable		 5ef1U-2fffB:
11.03
5ef1V-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5ef2A-2fffB:
undetectable
5ef2B-2fffB:
undetectable		 5ef2A-2fffB:
11.03
5ef2B-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5ef2B-2fffB:
undetectable
5ef2C-2fffB:
undetectable		 5ef2B-2fffB:
11.03
5ef2C-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 5ef2C-2fffB:
undetectable
5ef2D-2fffB:
undetectable		 5ef2C-2fffB:
11.03
5ef2D-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5ef2D-2fffB:
undetectable
5ef2E-2fffB:
undetectable		 5ef2D-2fffB:
11.03
5ef2E-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5ef2E-2fffB:
undetectable
5ef2F-2fffB:
undetectable		 5ef2E-2fffB:
11.03
5ef2F-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5ef2F-2fffB:
undetectable
5ef2G-2fffB:
undetectable		 5ef2F-2fffB:
11.03
5ef2G-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5ef2G-2fffB:
undetectable
5ef2H-2fffB:
undetectable		 5ef2G-2fffB:
11.03
5ef2H-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5ef2H-2fffB:
undetectable
5ef2I-2fffB:
undetectable		 5ef2H-2fffB:
11.03
5ef2I-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5ef2I-2fffB:
undetectable
5ef2J-2fffB:
undetectable		 5ef2I-2fffB:
11.03
5ef2J-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5ef2J-2fffB:
undetectable
5ef2K-2fffB:
undetectable		 5ef2J-2fffB:
11.03
5ef2K-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5ef2A-2fffB:
undetectable
5ef2K-2fffB:
undetectable		 5ef2A-2fffB:
11.03
5ef2K-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 8 GLY B 677
ALA B 688
THR B 417
HIS B 682
 None
None
None
NI  B 901 (-2.8A)
 0.87A 5ef2L-2fffB:
undetectable
5ef2V-2fffB:
undetectable		 5ef2L-2fffB:
11.03
5ef2V-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5ef2N-2fffB:
undetectable
5ef2O-2fffB:
undetectable		 5ef2N-2fffB:
11.03
5ef2O-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5ef2O-2fffB:
undetectable
5ef2P-2fffB:
undetectable		 5ef2O-2fffB:
11.03
5ef2P-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5ef2P-2fffB:
undetectable
5ef2Q-2fffB:
undetectable		 5ef2P-2fffB:
11.03
5ef2Q-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5ef2Q-2fffB:
undetectable
5ef2R-2fffB:
undetectable		 5ef2Q-2fffB:
11.03
5ef2R-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5ef2R-2fffB:
undetectable
5ef2S-2fffB:
undetectable		 5ef2R-2fffB:
11.03
5ef2S-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5ef2S-2fffB:
undetectable
5ef2T-2fffB:
undetectable		 5ef2S-2fffB:
11.03
5ef2T-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5ef2T-2fffB:
undetectable
5ef2U-2fffB:
undetectable		 5ef2T-2fffB:
11.03
5ef2U-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.05A 5ef2U-2fffB:
undetectable
5ef2V-2fffB:
undetectable		 5ef2U-2fffB:
11.03
5ef2V-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5ef3A-2fffB:
undetectable
5ef3B-2fffB:
undetectable		 5ef3A-2fffB:
11.03
5ef3B-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5ef3B-2fffB:
undetectable
5ef3C-2fffB:
undetectable		 5ef3B-2fffB:
11.03
5ef3C-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.12A 5ef3C-2fffB:
undetectable
5ef3D-2fffB:
undetectable		 5ef3C-2fffB:
11.03
5ef3D-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5ef3D-2fffB:
undetectable
5ef3E-2fffB:
undetectable		 5ef3D-2fffB:
11.03
5ef3E-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5ef3E-2fffB:
undetectable
5ef3F-2fffB:
undetectable		 5ef3E-2fffB:
11.03
5ef3F-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5ef3F-2fffB:
undetectable
5ef3G-2fffB:
undetectable		 5ef3F-2fffB:
11.03
5ef3G-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5ef3G-2fffB:
undetectable
5ef3H-2fffB:
undetectable		 5ef3G-2fffB:
11.03
5ef3H-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.09A 5ef3H-2fffB:
undetectable
5ef3I-2fffB:
undetectable		 5ef3H-2fffB:
11.03
5ef3I-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.11A 5ef3I-2fffB:
undetectable
5ef3J-2fffB:
undetectable		 5ef3I-2fffB:
11.03
5ef3J-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5ef3J-2fffB:
undetectable
5ef3K-2fffB:
undetectable		 5ef3J-2fffB:
11.03
5ef3K-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.10A 5ef3A-2fffB:
undetectable
5ef3K-2fffB:
undetectable		 5ef3A-2fffB:
11.03
5ef3K-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 8 GLY B 677
ALA B 688
THR B 417
HIS B 682
 None
None
None
NI  B 901 (-2.8A)
 0.88A 5ef3L-2fffB:
undetectable
5ef3V-2fffB:
undetectable		 5ef3L-2fffB:
11.03
5ef3V-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5ef3N-2fffB:
undetectable
5ef3O-2fffB:
undetectable		 5ef3N-2fffB:
11.03
5ef3O-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5ef3O-2fffB:
undetectable
5ef3P-2fffB:
undetectable		 5ef3O-2fffB:
11.03
5ef3P-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5ef3P-2fffB:
undetectable
5ef3Q-2fffB:
undetectable		 5ef3P-2fffB:
11.03
5ef3Q-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 9 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.04A 5ef3Q-2fffB:
undetectable
5ef3R-2fffB:
undetectable		 5ef3Q-2fffB:
11.03
5ef3R-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.02A 5ef3R-2fffB:
undetectable
5ef3S-2fffB:
undetectable		 5ef3R-2fffB:
11.03
5ef3S-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.08A 5ef3S-2fffB:
undetectable
5ef3T-2fffB:
undetectable		 5ef3S-2fffB:
11.03
5ef3T-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.03A 5ef3T-2fffB:
undetectable
5ef3U-2fffB:
undetectable		 5ef3T-2fffB:
11.03
5ef3U-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 10 GLY B 677
ALA B 688
THR B 417
HIS B 682
ILE B 676
 None
None
None
NI  B 901 (-2.8A)
None
 1.05A 5ef3U-2fffB:
undetectable
5ef3V-2fffB:
undetectable		 5ef3U-2fffB:
11.03
5ef3V-2fffB:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 11 ILE B 482
ASN B 485
LEU B 509
GLY B 510
ALA B 521
 None
 1.33A 5fctA-2fffB:
undetectable		 5fctA-2fffB:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 ALA B 459
SER B 460
SER B 516
ASN B 518
LYS B 651
GLY B 653
 None
 0.37A 5ghyA-2fffB:
16.5		 5ghyA-2fffB:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 ALA B 459
SER B 460
SER B 516
ASN B 518
LYS B 651
GLY B 653
 None
 0.35A 5ghyB-2fffB:
16.6		 5ghyB-2fffB:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		8 / 11 ALA B 459
SER B 460
TYR B 498
SER B 516
ASN B 518
LYS B 651
THR B 652
GLY B 653
 None
 0.41A 5ghzA-2fffB:
16.5		 5ghzA-2fffB:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		8 / 10 ALA B 459
SER B 460
TYR B 498
SER B 516
ASN B 518
LYS B 651
THR B 652
GLY B 653
 None
 0.40A 5ghzB-2fffB:
16.3		 5ghzB-2fffB:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 7 THR B 667
GLN B 705
ILE B 711
GLY B 713
 None
 0.91A 5nzyA-2fffB:
undetectable		 5nzyA-2fffB:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		5 / 12 ALA B 646
ALA B 644
PHE B 717
ALA B 575
PHE B 632
 None
 0.90A 5w4zA-2fffB:
undetectable		 5w4zA-2fffB:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 SER B 460
SER B 516
THR B 629
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.62A 6b5yB-2fffB:
5.0		 6b5yB-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 SER B 460
SER B 516
THR B 629
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.64A 6b5yD-2fffB:
16.4		 6b5yD-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 SER B 460
SER B 516
THR B 629
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.49A 6b68B-2fffB:
16.5		 6b68B-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 SER B 460
SER B 516
THR B 629
LYS B 651
GLY B 653
THR B 654
 None
 0.54A 6b68D-2fffB:
16.3		 6b68D-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 SER B 460
SER B 516
THR B 629
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.49A 6b69A-2fffB:
16.4
6b69B-2fffB:
16.4		 6b69A-2fffB:
9.71
6b69B-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 SER B 460
SER B 516
THR B 629
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.47A 6b69D-2fffB:
5.9		 6b69D-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 SER B 460
SER B 516
THR B 629
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.51A 6b6aB-2fffB:
16.4		 6b6aB-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 SER B 460
SER B 516
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.47A 6b6aD-2fffB:
16.3		 6b6aD-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 SER B 460
SER B 516
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.61A 6b6cA-2fffB:
16.4		 6b6cA-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 SER B 460
SER B 516
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.70A 6b6dA-2fffB:
16.4		 6b6dA-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 SER B 460
THR B 629
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.54A 6b6dA-2fffB:
16.4		 6b6dA-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		7 / 12 SER B 460
SER B 516
THR B 629
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.55A 6b6eA-2fffB:
16.7		 6b6eA-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 SER B 460
SER B 516
LYS B 651
THR B 652
GLY B 653
THR B 654
 None
 0.66A 6b6fA-2fffB:
16.4		 6b6fA-2fffB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		6 / 12 TYR B 498
SER B 516
ASN B 518
THR B 629
LYS B 651
GLY B 653
 None
 0.58A 6c79A-2fffB:
16.9		 6c79A-2fffB:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2fff PENICILLIN-BINDING
PROTEIN 1B
(Streptococcus
pneumoniae) 		4 / 5 GLY B 653
THR B 652
SER B 691
SER B 694
 None
 1.15A 6jmjA-2fffB:
undetectable		 6jmjA-2fffB:
16.86