SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2fg9 5-NITROIMIDAZOLE
ANTIBIOTIC
RESISTANCE PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 ALA A 155
TYR A  88
GLY A   0
GLY A 152
 None
 0.82A 1rukH-2fg9A:
undetectable
1rukL-2fg9A:
undetectable		 1rukH-2fg9A:
17.98
1rukL-2fg9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 2fg9 5-NITROIMIDAZOLE
ANTIBIOTIC
RESISTANCE PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 6 VAL A 143
TYR A  42
GLU A  13
ILE A  12
 None
 1.19A 3q5sA-2fg9A:
undetectable		 3q5sA-2fg9A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 2fg9 5-NITROIMIDAZOLE
ANTIBIOTIC
RESISTANCE PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 139
ILE A  58
GLY A  52
GLU A  54
 None
 1.06A 6gqiA-2fg9A:
undetectable		 6gqiA-2fg9A:
15.29