SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fhg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 4 ILE H 380
LEU H 383
VAL H 387
ALA H 393
 None
 0.93A 1mz9A-2fhgH:
undetectable		 1mz9A-2fhgH:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 4 ILE H 380
LEU H 383
VAL H 387
ALA H 394
 None
 0.97A 1mz9A-2fhgH:
undetectable		 1mz9A-2fhgH:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		3 / 3 ILE H 380
LEU H 383
VAL H 387
 None
 0.35A 1mz9B-2fhgH:
undetectable		 1mz9B-2fhgH:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 5 ILE H 380
LEU H 383
VAL H 387
ALA H 393
 None
 0.82A 1mz9C-2fhgH:
undetectable		 1mz9C-2fhgH:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 7 PHE H 491
ARG H 515
ALA H 514
PRO H 484
 None
 1.12A 1oniA-2fhgH:
undetectable
1oniB-2fhgH:
undetectable		 1oniA-2fhgH:
23.01
1oniB-2fhgH:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 7 PRO H 484
PHE H 491
ARG H 515
ALA H 514
 None
 1.02A 1oniD-2fhgH:
undetectable
1oniE-2fhgH:
undetectable		 1oniD-2fhgH:
23.01
1oniE-2fhgH:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 6 PHE H 491
ARG H 515
ALA H 514
PRO H 484
 None
 1.02A 1oniH-2fhgH:
undetectable
1oniI-2fhgH:
undetectable		 1oniH-2fhgH:
23.01
1oniI-2fhgH:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.58A 2f162-2fhgH:
25.8		 2f162-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.14A 2f16H-2fhgH:
25.0
2f16I-2fhgH:
24.0		 2f16H-2fhgH:
27.78
2f16I-2fhgH:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.47A 2f16H-2fhgH:
25.0
2f16I-2fhgH:
24.0		 2f16H-2fhgH:
27.78
2f16I-2fhgH:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
THR H 321
VAL H 331
LYS H 333
GLY H 347
ALA H 349
 None
 0.52A 2f16K-2fhgH:
25.9
2f16L-2fhgH:
22.6		 2f16K-2fhgH:
28.11
2f16L-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.58A 2f16N-2fhgH:
25.8		 2f16N-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.13A 2f16V-2fhgH:
25.0
2f16W-2fhgH:
24.0		 2f16V-2fhgH:
27.78
2f16W-2fhgH:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.49A 2f16V-2fhgH:
25.0
2f16W-2fhgH:
24.0		 2f16V-2fhgH:
27.78
2f16W-2fhgH:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
THR H 321
VAL H 331
LYS H 333
GLY H 347
ALA H 349
 None
 0.51A 2f16Y-2fhgH:
19.2
2f16Z-2fhgH:
22.3		 2f16Y-2fhgH:
28.11
2f16Z-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 6 ASP H 485
VAL H 487
PHE H 491
PRO H 484
 None
 1.47A 2q6oB-2fhgH:
undetectable		 2q6oB-2fhgH:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 4 GLY H 406
TYR H 407
GLY H 311
ASP H 498
 None
 1.19A 3kl3A-2fhgH:
undetectable		 3kl3A-2fhgH:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 LEU H 399
ASN H 390
VAL H 387
PHE H 423
LEU H 401
 None
 1.45A 3megA-2fhgH:
undetectable		 3megA-2fhgH:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.58A 3mg02-2fhgH:
25.7
3mg0V-2fhgH:
25.1		 3mg02-2fhgH:
25.00
3mg0V-2fhgH:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.14A 3mg0H-2fhgH:
25.0
3mg0I-2fhgH:
24.0		 3mg0H-2fhgH:
27.78
3mg0I-2fhgH:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		9 / 11 THR H 301
SER H 320
THR H 321
GLN H 322
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.59A 3mg0H-2fhgH:
25.0
3mg0I-2fhgH:
24.0		 3mg0H-2fhgH:
27.78
3mg0I-2fhgH:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 11 THR H 301
THR H 321
VAL H 331
LYS H 333
ALA H 346
GLY H 347
ALA H 349
SER H 441
 None
 0.60A 3mg0K-2fhgH:
25.9
3mg0L-2fhgH:
22.6		 3mg0K-2fhgH:
28.11
3mg0L-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
VAL H 331
LYS H 333
GLY H 347
ALA H 352
SER H 441
 None
 1.34A 3mg0K-2fhgH:
25.9
3mg0L-2fhgH:
22.6		 3mg0K-2fhgH:
28.11
3mg0L-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.58A 3mg0N-2fhgH:
25.8		 3mg0N-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.16A 3mg0V-2fhgH:
25.1
3mg0W-2fhgH:
24.0		 3mg0V-2fhgH:
27.78
3mg0W-2fhgH:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.50A 3mg0V-2fhgH:
25.1
3mg0W-2fhgH:
24.0		 3mg0V-2fhgH:
27.78
3mg0W-2fhgH:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 12 THR H 301
THR H 321
VAL H 331
LYS H 333
ALA H 346
GLY H 347
ALA H 349
SER H 441
 None
 0.63A 3mg0Y-2fhgH:
14.9
3mg0Z-2fhgH:
22.1		 3mg0Y-2fhgH:
28.11
3mg0Z-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 12 THR H 301
VAL H 331
LYS H 333
GLY H 347
ALA H 352
SER H 441
 None
 1.35A 3mg0Y-2fhgH:
14.9
3mg0Z-2fhgH:
22.1		 3mg0Y-2fhgH:
28.11
3mg0Z-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 7 ASP H 478
THR H 481
PHE H 445
SER H 443
 None
 1.48A 4o4dA-2fhgH:
undetectable		 4o4dA-2fhgH:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.59A 4qvlV-2fhgH:
25.0
4qvlb-2fhgH:
25.9		 4qvlV-2fhgH:
26.85
4qvlb-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 9 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 0.87A 4qvlH-2fhgH:
23.3
4qvlI-2fhgH:
24.0		 4qvlH-2fhgH:
26.85
4qvlI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.48A 4qvlK-2fhgH:
25.8
4qvlL-2fhgH:
22.6		 4qvlK-2fhgH:
28.11
4qvlL-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.59A 4qvlH-2fhgH:
23.3
4qvlN-2fhgH:
25.9		 4qvlH-2fhgH:
26.85
4qvlN-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 0.87A 4qvlV-2fhgH:
25.0
4qvlW-2fhgH:
24.0		 4qvlV-2fhgH:
26.85
4qvlW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
SER H 320
LYS H 333
ALA H 346
THR H 348
ALA H 349
 None
 0.44A 4qvlV-2fhgH:
25.0
4qvlW-2fhgH:
24.0		 4qvlV-2fhgH:
26.85
4qvlW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.48A 4qvlY-2fhgH:
14.9
4qvlZ-2fhgH:
22.2		 4qvlY-2fhgH:
28.11
4qvlZ-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.60A 4qvmV-2fhgH:
25.0
4qvmb-2fhgH:
25.8		 4qvmV-2fhgH:
26.85
4qvmb-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 349
 None
 0.83A 4qvmH-2fhgH:
23.5
4qvmI-2fhgH:
23.8		 4qvmH-2fhgH:
26.85
4qvmI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 THR H 301
SER H 320
LYS H 333
THR H 348
ALA H 349
 None
 0.43A 4qvmH-2fhgH:
23.5
4qvmI-2fhgH:
23.8		 4qvmH-2fhgH:
26.85
4qvmI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 9 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.51A 4qvmK-2fhgH:
25.7
4qvmL-2fhgH:
22.5		 4qvmK-2fhgH:
28.11
4qvmL-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.60A 4qvmH-2fhgH:
23.5
4qvmN-2fhgH:
25.8		 4qvmH-2fhgH:
26.85
4qvmN-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 349
 None
 0.83A 4qvmV-2fhgH:
25.0
4qvmW-2fhgH:
23.8		 4qvmV-2fhgH:
26.85
4qvmW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 THR H 301
SER H 320
LYS H 333
THR H 348
ALA H 349
 None
 0.43A 4qvmV-2fhgH:
25.0
4qvmW-2fhgH:
23.8		 4qvmV-2fhgH:
26.85
4qvmW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.50A 4qvmY-2fhgH:
14.8
4qvmZ-2fhgH:
22.1		 4qvmY-2fhgH:
28.11
4qvmZ-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.57A 4qvnV-2fhgH:
25.1
4qvnb-2fhgH:
25.8		 4qvnV-2fhgH:
26.85
4qvnb-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 349
 None
 0.88A 4qvnH-2fhgH:
23.3
4qvnI-2fhgH:
24.0		 4qvnH-2fhgH:
26.85
4qvnI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
LYS H 333
GLY H 347
THR H 348
ALA H 349
 None
 0.40A 4qvnH-2fhgH:
23.3
4qvnI-2fhgH:
24.0		 4qvnH-2fhgH:
26.85
4qvnI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 9 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.48A 4qvnK-2fhgH:
25.9
4qvnL-2fhgH:
22.6		 4qvnK-2fhgH:
28.11
4qvnL-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.57A 4qvnH-2fhgH:
23.3
4qvnN-2fhgH:
25.8		 4qvnH-2fhgH:
26.85
4qvnN-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 349
 None
 0.89A 4qvnV-2fhgH:
25.1
4qvnW-2fhgH:
24.1		 4qvnV-2fhgH:
26.85
4qvnW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
SER H 320
LYS H 333
GLY H 347
THR H 348
ALA H 349
 None
 0.41A 4qvnV-2fhgH:
25.1
4qvnW-2fhgH:
24.1		 4qvnV-2fhgH:
26.85
4qvnW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 9 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.49A 4qvnY-2fhgH:
15.0
4qvnZ-2fhgH:
22.2		 4qvnY-2fhgH:
28.11
4qvnZ-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.55A 4qvpV-2fhgH:
25.1
4qvpb-2fhgH:
25.9		 4qvpV-2fhgH:
26.85
4qvpb-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.09A 4qvpH-2fhgH:
23.4
4qvpI-2fhgH:
23.9		 4qvpH-2fhgH:
26.85
4qvpI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
GLY H 347
ALA H 349
 None
 0.80A 4qvpH-2fhgH:
23.4
4qvpI-2fhgH:
23.9		 4qvpH-2fhgH:
26.85
4qvpI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
SER H 320
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.39A 4qvpH-2fhgH:
23.4
4qvpI-2fhgH:
23.9		 4qvpH-2fhgH:
26.85
4qvpI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.46A 4qvpK-2fhgH:
25.8
4qvpL-2fhgH:
22.3		 4qvpK-2fhgH:
28.11
4qvpL-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.54A 4qvpH-2fhgH:
23.4
4qvpN-2fhgH:
25.9		 4qvpH-2fhgH:
26.85
4qvpN-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.09A 4qvpV-2fhgH:
25.1
4qvpW-2fhgH:
24.0		 4qvpV-2fhgH:
26.85
4qvpW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
GLY H 347
ALA H 349
 None
 0.80A 4qvpV-2fhgH:
25.1
4qvpW-2fhgH:
24.0		 4qvpV-2fhgH:
26.85
4qvpW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
SER H 320
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.39A 4qvpV-2fhgH:
25.1
4qvpW-2fhgH:
24.0		 4qvpV-2fhgH:
26.85
4qvpW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.45A 4qvpY-2fhgH:
14.9
4qvpZ-2fhgH:
22.2		 4qvpY-2fhgH:
28.11
4qvpZ-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.55A 4qvqV-2fhgH:
25.1
4qvqb-2fhgH:
25.8		 4qvqV-2fhgH:
26.85
4qvqb-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
GLY H 347
ALA H 349
 None
 0.85A 4qvqH-2fhgH:
23.3
4qvqI-2fhgH:
23.9		 4qvqH-2fhgH:
26.85
4qvqI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
LYS H 333
GLY H 347
THR H 348
ALA H 349
 None
 0.39A 4qvqH-2fhgH:
23.3
4qvqI-2fhgH:
23.9		 4qvqH-2fhgH:
26.85
4qvqI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 9 THR H 301
THR H 321
LYS H 333
ILE H 345
GLY H 347
ALA H 349
 None
 0.99A 4qvqK-2fhgH:
25.8
4qvqL-2fhgH:
22.5		 4qvqK-2fhgH:
28.51
4qvqL-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.56A 4qvqH-2fhgH:
23.3
4qvqN-2fhgH:
25.8		 4qvqH-2fhgH:
26.85
4qvqN-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
GLY H 347
ALA H 349
 None
 0.85A 4qvqV-2fhgH:
25.1
4qvqW-2fhgH:
23.9		 4qvqV-2fhgH:
26.85
4qvqW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
LYS H 333
GLY H 347
THR H 348
ALA H 349
 None
 0.38A 4qvqV-2fhgH:
25.1
4qvqW-2fhgH:
23.9		 4qvqV-2fhgH:
26.85
4qvqW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 9 THR H 301
THR H 321
LYS H 333
ILE H 345
GLY H 347
ALA H 349
 None
 0.98A 4qvqY-2fhgH:
15.0
4qvqZ-2fhgH:
22.1		 4qvqY-2fhgH:
28.51
4qvqZ-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.10A 4qvvH-2fhgH:
23.5		 4qvvH-2fhgH:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 11 THR H 301
SER H 320
THR H 321
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 1.01A 4qvvH-2fhgH:
23.5		 4qvvH-2fhgH:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 11 THR H 301
SER H 320
THR H 321
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.51A 4qvvH-2fhgH:
23.5		 4qvvH-2fhgH:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 THR H 301
THR H 321
LYS H 333
GLY H 347
 None
 0.58A 4qvvK-2fhgH:
25.6
4qvvL-2fhgH:
22.4		 4qvvK-2fhgH:
28.11
4qvvL-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.10A 4qvvV-2fhgH:
25.1		 4qvvV-2fhgH:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 11 THR H 301
SER H 320
THR H 321
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 1.01A 4qvvV-2fhgH:
25.1		 4qvvV-2fhgH:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 11 THR H 301
SER H 320
THR H 321
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.50A 4qvvV-2fhgH:
25.1		 4qvvV-2fhgH:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 THR H 301
THR H 321
LYS H 333
GLY H 347
 None
 0.58A 4qvvY-2fhgH:
14.7
4qvvZ-2fhgH:
22.0		 4qvvY-2fhgH:
28.11
4qvvZ-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.59A 4qvwV-2fhgH:
25.1
4qvwb-2fhgH:
25.9		 4qvwV-2fhgH:
26.85
4qvwb-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 0.86A 4qvwH-2fhgH:
23.4
4qvwI-2fhgH:
23.9		 4qvwH-2fhgH:
26.85
4qvwI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
SER H 320
LYS H 333
ALA H 346
THR H 348
ALA H 349
 None
 0.45A 4qvwH-2fhgH:
23.4
4qvwI-2fhgH:
23.9		 4qvwH-2fhgH:
26.85
4qvwI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.59A 4qvwH-2fhgH:
23.4
4qvwN-2fhgH:
25.9		 4qvwH-2fhgH:
26.85
4qvwN-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 0.86A 4qvwV-2fhgH:
25.1
4qvwW-2fhgH:
23.9		 4qvwV-2fhgH:
26.85
4qvwW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
SER H 320
LYS H 333
ALA H 346
THR H 348
ALA H 349
 None
 0.44A 4qvwV-2fhgH:
25.1
4qvwW-2fhgH:
23.9		 4qvwV-2fhgH:
26.85
4qvwW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.11A 4qvyH-2fhgH:
21.7		 4qvyH-2fhgH:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
THR H 321
GLN H 322
LYS H 333
ALA H 349
 None
 1.02A 4qvyH-2fhgH:
21.7		 4qvyH-2fhgH:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 11 THR H 301
SER H 320
THR H 321
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.51A 4qvyH-2fhgH:
21.7		 4qvyH-2fhgH:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.11A 4qvyV-2fhgH:
25.1
4qvyW-2fhgH:
24.0		 4qvyV-2fhgH:
26.85
4qvyW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 349
 None
 0.93A 4qvyV-2fhgH:
25.1
4qvyW-2fhgH:
24.0		 4qvyV-2fhgH:
26.85
4qvyW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
SER H 320
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.43A 4qvyV-2fhgH:
25.1
4qvyW-2fhgH:
24.0		 4qvyV-2fhgH:
26.85
4qvyW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.61A 4qw0V-2fhgH:
25.1
4qw0b-2fhgH:
25.8		 4qw0V-2fhgH:
26.85
4qw0b-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.08A 4qw0H-2fhgH:
23.4
4qw0I-2fhgH:
23.8		 4qw0H-2fhgH:
26.85
4qw0I-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 0.89A 4qw0H-2fhgH:
23.4
4qw0I-2fhgH:
23.8		 4qw0H-2fhgH:
26.85
4qw0I-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 11 THR H 301
SER H 320
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.41A 4qw0H-2fhgH:
23.4
4qw0I-2fhgH:
23.8		 4qw0H-2fhgH:
26.85
4qw0I-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.60A 4qw0H-2fhgH:
23.4
4qw0N-2fhgH:
25.9		 4qw0H-2fhgH:
26.85
4qw0N-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.08A 4qw0V-2fhgH:
25.1
4qw0W-2fhgH:
23.9		 4qw0V-2fhgH:
26.85
4qw0W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 0.89A 4qw0V-2fhgH:
25.1
4qw0W-2fhgH:
23.9		 4qw0V-2fhgH:
26.85
4qw0W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 11 THR H 301
SER H 320
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.42A 4qw0V-2fhgH:
25.1
4qw0W-2fhgH:
23.9		 4qw0V-2fhgH:
26.85
4qw0W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.58A 4qw1V-2fhgH:
25.1
4qw1b-2fhgH:
26.0		 4qw1V-2fhgH:
26.85
4qw1b-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.10A 4qw1H-2fhgH:
23.4
4qw1I-2fhgH:
23.9		 4qw1H-2fhgH:
26.85
4qw1I-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 349
 None
 0.91A 4qw1H-2fhgH:
23.4
4qw1I-2fhgH:
23.9		 4qw1H-2fhgH:
26.85
4qw1I-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
SER H 320
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.42A 4qw1H-2fhgH:
23.4
4qw1I-2fhgH:
23.9		 4qw1H-2fhgH:
26.85
4qw1I-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.48A 4qw1K-2fhgH:
25.8
4qw1L-2fhgH:
22.6		 4qw1K-2fhgH:
28.35
4qw1L-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.58A 4qw1H-2fhgH:
23.4
4qw1N-2fhgH:
25.8		 4qw1H-2fhgH:
26.85
4qw1N-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.10A 4qw1V-2fhgH:
25.1
4qw1W-2fhgH:
24.0		 4qw1V-2fhgH:
26.85
4qw1W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 349
 None
 0.90A 4qw1V-2fhgH:
25.1
4qw1W-2fhgH:
24.0		 4qw1V-2fhgH:
26.85
4qw1W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
SER H 320
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.43A 4qw1V-2fhgH:
25.1
4qw1W-2fhgH:
24.0		 4qw1V-2fhgH:
26.85
4qw1W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.48A 4qw1Y-2fhgH:
14.8
4qw1Z-2fhgH:
22.2		 4qw1Y-2fhgH:
28.35
4qw1Z-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.59A 4qw3V-2fhgH:
25.1
4qw3b-2fhgH:
25.8		 4qw3V-2fhgH:
26.85
4qw3b-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 0.78A 4qw3H-2fhgH:
23.4
4qw3I-2fhgH:
23.7		 4qw3H-2fhgH:
26.85
4qw3I-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
SER H 320
LYS H 333
ALA H 346
THR H 348
ALA H 349
 None
 0.42A 4qw3H-2fhgH:
23.4
4qw3I-2fhgH:
23.7		 4qw3H-2fhgH:
26.85
4qw3I-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.52A 4qw3K-2fhgH:
25.7
4qw3L-2fhgH:
22.3		 4qw3K-2fhgH:
28.11
4qw3L-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.59A 4qw3H-2fhgH:
23.4
4qw3N-2fhgH:
25.8		 4qw3H-2fhgH:
26.85
4qw3N-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 0.78A 4qw3V-2fhgH:
25.1
4qw3W-2fhgH:
23.8		 4qw3V-2fhgH:
26.85
4qw3W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
LYS H 333
ALA H 346
THR H 348
ALA H 349
 None
 0.42A 4qw3V-2fhgH:
25.1
4qw3W-2fhgH:
23.8		 4qw3V-2fhgH:
26.85
4qw3W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.52A 4qw3Y-2fhgH:
19.1
4qw3Z-2fhgH:
22.0		 4qw3Y-2fhgH:
28.11
4qw3Z-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.55A 4qwuV-2fhgH:
25.1
4qwub-2fhgH:
25.9		 4qwuV-2fhgH:
26.85
4qwub-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
GLY H 347
ALA H 349
 None
 0.86A 4qwuH-2fhgH:
23.4
4qwuI-2fhgH:
24.0		 4qwuH-2fhgH:
26.85
4qwuI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
LYS H 333
GLY H 347
THR H 348
ALA H 349
 None
 0.41A 4qwuH-2fhgH:
23.4
4qwuI-2fhgH:
24.0		 4qwuH-2fhgH:
26.85
4qwuI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.55A 4qwuH-2fhgH:
23.4
4qwuN-2fhgH:
25.9		 4qwuH-2fhgH:
26.85
4qwuN-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
GLY H 347
ALA H 349
 None
 0.86A 4qwuV-2fhgH:
25.1
4qwuW-2fhgH:
24.0		 4qwuV-2fhgH:
26.85
4qwuW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
LYS H 333
GLY H 347
THR H 348
ALA H 349
 None
 0.41A 4qwuV-2fhgH:
25.1
4qwuW-2fhgH:
24.0		 4qwuV-2fhgH:
26.85
4qwuW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.57A 5bxnV-2fhgH:
25.2
5bxnb-2fhgH:
25.8		 5bxnV-2fhgH:
26.77
5bxnb-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.13A 5bxnH-2fhgH:
25.2
5bxnI-2fhgH:
24.0		 5bxnH-2fhgH:
26.77
5bxnI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.47A 5bxnH-2fhgH:
25.2
5bxnI-2fhgH:
24.0		 5bxnH-2fhgH:
26.77
5bxnI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.45A 5bxnK-2fhgH:
25.9
5bxnL-2fhgH:
22.3		 5bxnK-2fhgH:
28.11
5bxnL-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.56A 5bxnH-2fhgH:
25.2
5bxnN-2fhgH:
25.9		 5bxnH-2fhgH:
26.77
5bxnN-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.13A 5bxnV-2fhgH:
25.2
5bxnW-2fhgH:
24.1		 5bxnV-2fhgH:
26.77
5bxnW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		9 / 11 THR H 301
SER H 320
THR H 321
GLN H 322
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.50A 5bxnV-2fhgH:
25.2
5bxnW-2fhgH:
24.1		 5bxnV-2fhgH:
26.77
5bxnW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.46A 5bxnY-2fhgH:
14.9
5bxnZ-2fhgH:
22.2		 5bxnY-2fhgH:
28.11
5bxnZ-2fhgH:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 0.85A 5cz7H-2fhgH:
23.5
5cz7I-2fhgH:
23.9		 5cz7H-2fhgH:
26.85
5cz7I-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
SER H 320
LYS H 333
ALA H 346
THR H 348
ALA H 349
 None
 0.40A 5cz7H-2fhgH:
23.5
5cz7I-2fhgH:
23.9		 5cz7H-2fhgH:
26.85
5cz7I-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.56A 5cz7H-2fhgH:
23.5
5cz7N-2fhgH:
25.9		 5cz7H-2fhgH:
26.85
5cz7N-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.11A 5cz7V-2fhgH:
25.1
5cz7W-2fhgH:
23.9		 5cz7V-2fhgH:
26.85
5cz7W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
GLY H 347
ALA H 349
 None
 0.81A 5cz7V-2fhgH:
25.1
5cz7W-2fhgH:
23.9		 5cz7V-2fhgH:
26.85
5cz7W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
SER H 320
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.38A 5cz7V-2fhgH:
25.1
5cz7W-2fhgH:
23.9		 5cz7V-2fhgH:
26.85
5cz7W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.59A 5d0xV-2fhgH:
25.1
5d0xb-2fhgH:
25.8		 5d0xV-2fhgH:
26.85
5d0xb-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
SER H 320
THR H 321
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 0.92A 5d0xH-2fhgH:
23.5
5d0xI-2fhgH:
23.8		 5d0xH-2fhgH:
26.85
5d0xI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
SER H 320
THR H 321
LYS H 333
ALA H 346
THR H 348
ALA H 349
 None
 0.51A 5d0xH-2fhgH:
23.5
5d0xI-2fhgH:
23.8		 5d0xH-2fhgH:
26.85
5d0xI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.58A 5d0xH-2fhgH:
23.5
5d0xN-2fhgH:
25.8		 5d0xH-2fhgH:
26.85
5d0xN-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.09A 5d0xV-2fhgH:
25.1		 5d0xV-2fhgH:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 11 THR H 301
SER H 320
THR H 321
GLN H 322
LYS H 333
ALA H 346
ALA H 349
 None
 0.92A 5d0xV-2fhgH:
25.1		 5d0xV-2fhgH:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 11 THR H 301
SER H 320
THR H 321
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.49A 5d0xV-2fhgH:
25.1		 5d0xV-2fhgH:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 6 THR H 337
ALA H 342
THR H 343
VAL H 334
 None
 0.83A 5ecoA-2fhgH:
undetectable		 5ecoA-2fhgH:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.09A 5l5fH-2fhgH:
23.4
5l5fI-2fhgH:
23.9		 5l5fH-2fhgH:
26.85
5l5fI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 12 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.58A 5l5fH-2fhgH:
23.4
5l5fI-2fhgH:
23.9		 5l5fH-2fhgH:
26.85
5l5fI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 9 THR H 301
SER H 327
VAL H 331
LYS H 333
ALA H 349
 None
 0.43A 5l5fK-2fhgH:
25.6
5l5fL-2fhgH:
22.1		 5l5fK-2fhgH:
26.67
5l5fL-2fhgH:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.09A 5l5fV-2fhgH:
25.1
5l5fW-2fhgH:
23.9		 5l5fV-2fhgH:
26.85
5l5fW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 12 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.57A 5l5fV-2fhgH:
25.1
5l5fW-2fhgH:
23.9		 5l5fV-2fhgH:
26.85
5l5fW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 THR H 301
SER H 327
LYS H 333
ALA H 349
 None
 0.42A 5l5fY-2fhgH:
25.6
5l5fZ-2fhgH:
22.0		 5l5fY-2fhgH:
26.67
5l5fZ-2fhgH:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.55A 5l5zV-2fhgH:
25.1
5l5zb-2fhgH:
25.9		 5l5zV-2fhgH:
26.85
5l5zb-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.10A 5l5zH-2fhgH:
23.4
5l5zI-2fhgH:
24.0		 5l5zH-2fhgH:
26.85
5l5zI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 12 THR H 301
SER H 320
THR H 321
GLN H 322
LYS H 333
ALA H 346
GLY H 347
ALA H 349
 None
 0.71A 5l5zH-2fhgH:
23.4
5l5zI-2fhgH:
24.0		 5l5zH-2fhgH:
26.85
5l5zI-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 9 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.47A 5l5zK-2fhgH:
25.5
5l5zL-2fhgH:
22.2		 5l5zK-2fhgH:
29.17
5l5zL-2fhgH:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.55A 5l5zH-2fhgH:
23.4
5l5zN-2fhgH:
25.9		 5l5zH-2fhgH:
26.85
5l5zN-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.10A 5l5zV-2fhgH:
25.1
5l5zW-2fhgH:
24.0		 5l5zV-2fhgH:
26.85
5l5zW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 12 THR H 301
SER H 320
THR H 321
GLN H 322
LYS H 333
ALA H 346
GLY H 347
ALA H 349
 None
 0.71A 5l5zV-2fhgH:
25.1
5l5zW-2fhgH:
24.0		 5l5zV-2fhgH:
26.85
5l5zW-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 9 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.47A 5l5zY-2fhgH:
25.5
5l5zZ-2fhgH:
22.0		 5l5zY-2fhgH:
29.17
5l5zZ-2fhgH:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.54A 5l66V-2fhgH:
25.2
5l66b-2fhgH:
25.9		 5l66V-2fhgH:
26.85
5l66b-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.11A 5l66H-2fhgH:
23.3
5l66I-2fhgH:
24.0		 5l66H-2fhgH:
26.85
5l66I-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 12 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.71A 5l66H-2fhgH:
23.3
5l66I-2fhgH:
24.0		 5l66H-2fhgH:
26.85
5l66I-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
THR H 321
SER H 327
LYS H 333
GLY H 347
ALA H 349
 None
 0.47A 5l66K-2fhgH:
25.6
5l66L-2fhgH:
22.4		 5l66K-2fhgH:
27.08
5l66L-2fhgH:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.54A 5l66H-2fhgH:
23.3
5l66N-2fhgH:
25.9		 5l66H-2fhgH:
26.85
5l66N-2fhgH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
LYS H 333
ALA H 346
GLY H 347
ALA H 352
 None
 1.11A 5l66V-2fhgH:
25.2
5l66W-2fhgH:
24.0		 5l66V-2fhgH:
26.85
5l66W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		8 / 12 THR H 301
SER H 320
GLN H 322
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.71A 5l66V-2fhgH:
25.2
5l66W-2fhgH:
24.0		 5l66V-2fhgH:
26.85
5l66W-2fhgH:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
THR H 321
SER H 327
LYS H 333
GLY H 347
ALA H 349
 None
 0.48A 5l66Y-2fhgH:
25.5
5l66Z-2fhgH:
22.0		 5l66Y-2fhgH:
27.08
5l66Z-2fhgH:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.57A 5lf3b-2fhgH:
25.5		 5lf3b-2fhgH:
26.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 THR H 301
THR H 321
ALA H 346
GLY H 347
ALA H 349
 None
 0.44A 5lf3H-2fhgH:
25.7
5lf3I-2fhgH:
24.0		 5lf3H-2fhgH:
22.92
5lf3I-2fhgH:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.44A 5lf3K-2fhgH:
26.0
5lf3L-2fhgH:
23.1		 5lf3K-2fhgH:
29.34
5lf3L-2fhgH:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.56A 5lf3N-2fhgH:
25.6		 5lf3N-2fhgH:
26.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 10 THR H 301
THR H 321
LYS H 333
ALA H 346
GLY H 347
ALA H 349
 None
 0.44A 5lf3V-2fhgH:
25.6
5lf3W-2fhgH:
24.0		 5lf3V-2fhgH:
22.92
5lf3W-2fhgH:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.45A 5lf3Y-2fhgH:
25.9
5lf3Z-2fhgH:
23.1		 5lf3Y-2fhgH:
29.34
5lf3Z-2fhgH:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.60A 5lf7V-2fhgH:
25.6
5lf7b-2fhgH:
25.6		 5lf7V-2fhgH:
22.92
5lf7b-2fhgH:
26.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
ALA H 346
GLY H 347
ALA H 349
 None
 0.46A 5lf7H-2fhgH:
25.6
5lf7I-2fhgH:
24.1		 5lf7H-2fhgH:
22.92
5lf7I-2fhgH:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
THR H 321
VAL H 331
LYS H 333
GLY H 347
ALA H 349
 None
 0.48A 5lf7K-2fhgH:
26.0
5lf7L-2fhgH:
23.2		 5lf7K-2fhgH:
29.34
5lf7L-2fhgH:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.58A 5lf7H-2fhgH:
25.6
5lf7N-2fhgH:
25.7		 5lf7H-2fhgH:
22.92
5lf7N-2fhgH:
26.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
ALA H 346
GLY H 347
ALA H 349
 None
 0.45A 5lf7V-2fhgH:
25.6
5lf7W-2fhgH:
24.1		 5lf7V-2fhgH:
22.92
5lf7W-2fhgH:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		6 / 11 THR H 301
THR H 321
VAL H 331
LYS H 333
GLY H 347
ALA H 349
 None
 0.49A 5lf7Y-2fhgH:
25.9
5lf7Z-2fhgH:
23.2		 5lf7Y-2fhgH:
29.34
5lf7Z-2fhgH:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.56A 6hwdV-2fhgH:
25.0
6hwdb-2fhgH:
25.9		 6hwdV-2fhgH:
25.73
6hwdb-2fhgH:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
GLN H 322
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.60A 6hwdH-2fhgH:
23.4
6hwdI-2fhgH:
24.0		 6hwdH-2fhgH:
25.73
6hwdI-2fhgH:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 12 THR H 301
SER H 320
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.49A 6hwdH-2fhgH:
23.4
6hwdI-2fhgH:
24.0		 6hwdH-2fhgH:
25.73
6hwdI-2fhgH:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.46A 6hwdK-2fhgH:
25.8
6hwdL-2fhgH:
22.6		 6hwdK-2fhgH:
17.47
6hwdL-2fhgH:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.56A 6hwdH-2fhgH:
23.4
6hwdN-2fhgH:
25.9		 6hwdH-2fhgH:
25.73
6hwdN-2fhgH:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 11 THR H 301
GLN H 322
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.60A 6hwdV-2fhgH:
25.0		 6hwdV-2fhgH:
25.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		7 / 11 THR H 301
SER H 320
LYS H 333
ALA H 346
GLY H 347
THR H 348
ALA H 349
 None
 0.49A 6hwdV-2fhgH:
25.0		 6hwdV-2fhgH:
25.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2fhg PROTEASOME, BETA
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 THR H 301
THR H 321
LYS H 333
GLY H 347
ALA H 349
 None
 0.45A 6hwdY-2fhgH:
15.0
6hwdZ-2fhgH:
22.2		 6hwdY-2fhgH:
17.47
6hwdZ-2fhgH:
16.89