SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fhp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 11 GLY A  53
ILE A  80
LYS A  81
PRO A  90
THR A  87
 None
 1.31A 3bjwB-2fhpA:
undetectable		 3bjwB-2fhpA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 11 GLY A  53
ILE A  80
LYS A  81
PRO A  90
THR A  87
 None
 1.36A 3bjwE-2fhpA:
undetectable		 3bjwE-2fhpA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 12 LEU A  48
LEU A  46
TYR A  49
ALA A  56
THR A  24
 None
 1.24A 3gwuA-2fhpA:
undetectable		 3gwuA-2fhpA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 9 LEU A 140
PHE A 114
VAL A 117
ILE A  68
ALA A 100
 None
 1.00A 3mdtA-2fhpA:
undetectable		 3mdtA-2fhpA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DMG_A_SAMA401_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493)		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 12 TYR A  49
LYS A  72
ALA A 100
ASP A 120
PRO A 122
 None
 0.70A 4dmgA-2fhpA:
16.3		 4dmgA-2fhpA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DMG_B_SAMB401_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493)		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 11 TYR A  49
LYS A  72
ALA A 100
ASP A 120
PRO A 122
 None
 0.68A 4dmgB-2fhpA:
15.9		 4dmgB-2fhpA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 12 GLY A  51
GLY A  53
LEU A  13
ILE A  70
ALA A  76
 None
 0.92A 4qtuB-2fhpA:
12.2		 4qtuB-2fhpA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 12 GLY A  51
GLY A  53
GLY A  54
LEU A  55
ASP A 120
 None
 0.96A 5c0oF-2fhpA:
14.8		 5c0oF-2fhpA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 12 GLY A  53
GLY A  54
LEU A  55
ALA A 100
ASP A 120
 None
 0.93A 5c0oF-2fhpA:
14.8		 5c0oF-2fhpA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 12 ASP A  99
ALA A 100
ASP A 120
PRO A 122
GLY A  51
 None
 1.02A 5hfjA-2fhpA:
4.5		 5hfjA-2fhpA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 12 ALA A 100
ASP A 120
PRO A 122
GLY A  51
SER A  52
 None
 0.96A 5hfjB-2fhpA:
4.5		 5hfjB-2fhpA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		6 / 12 ASP A  99
ALA A 100
ASP A 120
PRO A 122
GLY A  51
SER A  52
 None
 0.99A 5hfjD-2fhpA:
6.5		 5hfjD-2fhpA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 12 ASP A  99
ALA A 100
ASP A 120
GLY A  51
SER A  52
 None
 0.77A 5hfjE-2fhpA:
6.5		 5hfjE-2fhpA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		6 / 12 ASP A  99
ALA A 100
ASP A 120
PRO A 122
GLY A  51
SER A  52
 None
 0.97A 5hfjF-2fhpA:
6.5		 5hfjF-2fhpA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 12 ASP A  99
ALA A 100
ASP A 120
PRO A 122
GLY A  51
 None
 0.89A 5hfjH-2fhpA:
6.4		 5hfjH-2fhpA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		3 / 3 LEU A 132
LEU A 119
ARG A 102
 None
 0.53A 5hnzB-2fhpA:
undetectable		 5hnzB-2fhpA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 12 GLY A  54
LYS A  72
ASP A  99
ALA A 100
PRO A 122
 None
 1.08A 5zvgA-2fhpA:
12.8		 5zvgA-2fhpA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 2fhp METHYLASE, PUTATIVE
(Enterococcus
faecalis) 		5 / 12 GLY A  54
LYS A  72
ASP A  99
ALA A 100
PRO A 122
 None
 1.06A 5zvgB-2fhpA:
12.8		 5zvgB-2fhpA:
20.31