SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fia'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 2fia ACETYLTRANSFERASE
(Enterococcus
faecalis) 		4 / 4 VAL A  21
LEU A 100
ILE A   3
LEU A  54
 None
 1.04A 2byoA-2fiaA:
undetectable		 2byoA-2fiaA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 2fia ACETYLTRANSFERASE
(Enterococcus
faecalis) 		3 / 3 PHE A 126
SER A  63
LEU A  95
 None
 0.66A 2w1bA-2fiaA:
undetectable		 2w1bA-2fiaA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 2fia ACETYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 12 PRO A  38
LEU A  18
ILE A  47
VAL A  56
LEU A  54
 None
 1.42A 3a51B-2fiaA:
undetectable		 3a51B-2fiaA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 2fia ACETYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 PHE A 126
PHE A 127
PHE A  81
ALA A  82
ILE A  88
 None
 1.29A 3t3qA-2fiaA:
undetectable		 3t3qA-2fiaA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 2fia ACETYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 PHE A 126
PHE A 127
PHE A  81
ALA A  82
ILE A  88
 None
 1.28A 3t3qB-2fiaA:
undetectable		 3t3qB-2fiaA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 2fia ACETYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 PHE A 126
PHE A 127
PHE A  81
ALA A  82
ILE A  88
 None
 1.28A 3t3qC-2fiaA:
undetectable		 3t3qC-2fiaA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 2fia ACETYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 PHE A 126
PHE A 127
PHE A  81
ALA A  82
ILE A  88
 None
 1.23A 3t3qD-2fiaA:
undetectable		 3t3qD-2fiaA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2fia ACETYLTRANSFERASE
(Enterococcus
faecalis) 		3 / 3 MET A  64
ASP A  46
ARG A 143
 None
 1.18A 5z6jA-2fiaA:
undetectable		 5z6jA-2fiaA:
15.91