SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fin'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 2fin RABBITPOX ENCODED CC
CHEMOKINE INHIBITOR
(Vaccinia
virus) 		5 / 10 SER A 102
ILE A  26
PRO A  98
SER A 120
GLY A  25
 None
 1.47A 3ik6B-2finA:
undetectable
3ik6E-2finA:
undetectable		 3ik6B-2finA:
20.44
3ik6E-2finA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 2fin RABBITPOX ENCODED CC
CHEMOKINE INHIBITOR
(Vaccinia
virus) 		5 / 10 SER A 127
SER A 102
ILE A  26
PRO A  98
GLY A  25
 None
 1.42A 3ik6B-2finA:
undetectable
3ik6E-2finA:
undetectable		 3ik6B-2finA:
20.44
3ik6E-2finA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 2fin RABBITPOX ENCODED CC
CHEMOKINE INHIBITOR
(Vaccinia
virus) 		3 / 3 TYR A  80
ARG A  89
SER A  82
 None
 0.90A 4khpI-2finA:
undetectable
4khpJ-2finA:
1.2		 4khpI-2finA:
18.42
4khpJ-2finA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2fin RABBITPOX ENCODED CC
CHEMOKINE INHIBITOR
(Vaccinia
virus) 		3 / 3 ASP A 201
VAL A 211
ASN A 168
 None
 0.75A 4lmnA-2finA:
undetectable		 4lmnA-2finA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 2fin RABBITPOX ENCODED CC
CHEMOKINE INHIBITOR
(Vaccinia
virus) 		5 / 12 ILE A 184
GLY A 181
ILE A 180
ARG A  89
ALA A 114
 None
 0.97A 5e72A-2finA:
undetectable		 5e72A-2finA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 2fin RABBITPOX ENCODED CC
CHEMOKINE INHIBITOR
(Vaccinia
virus) 		4 / 4 VAL A 112
GLU A 105
GLY A  86
LEU A  88
 None
 1.25A 5g5gC-2finA:
undetectable		 5g5gC-2finA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 2fin RABBITPOX ENCODED CC
CHEMOKINE INHIBITOR
(Vaccinia
virus) 		5 / 12 ILE A  30
VAL A 144
ILE A 180
LEU A 193
THR A 183
 None
 1.21A 5tiwA-2finA:
undetectable		 5tiwA-2finA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 2fin RABBITPOX ENCODED CC
CHEMOKINE INHIBITOR
(Vaccinia
virus) 		3 / 3 GLU A  63
ASP A  59
PRO A  58
 None
 0.78A 6berA-2finA:
undetectable		 6berA-2finA:
4.00