SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fiq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		5 / 10 GLU A 317
GLU A 316
ALA A 313
LEU A 312
GLU A 322
 None
 1.40A 1a29A-2fiqA:
undetectable		 1a29A-2fiqA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		5 / 12 ASN A 360
LEU A 295
ILE A 292
ALA A 291
LEU A  25
 None
 0.99A 3a50A-2fiqA:
undetectable		 3a50A-2fiqA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		4 / 5 VAL A 280
VAL A  19
GLN A  49
PHE A 286
 None
 1.11A 3bjwH-2fiqA:
0.4		 3bjwH-2fiqA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		5 / 10 LEU A 288
LYS A 359
ILE A 315
ILE A 341
PHE A 293
 None
 1.26A 3kz7A-2fiqA:
undetectable		 3kz7A-2fiqA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		3 / 3 LYS A 120
VAL A 167
HIS A 122
 None
 1.22A 3tj7A-2fiqA:
undetectable		 3tj7A-2fiqA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		4 / 5 GLY A 281
THR A 285
ILE A  27
VAL A  26
 None
 0.89A 3wriA-2fiqA:
undetectable		 3wriA-2fiqA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		4 / 5 GLY A 281
THR A 285
ILE A  27
VAL A  26
 None
 0.88A 3wriB-2fiqA:
undetectable		 3wriB-2fiqA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		3 / 3 TYR A 166
ARG A 215
SER A 165
 None
 1.01A 4dr2I-2fiqA:
undetectable
4dr2J-2fiqA:
undetectable		 4dr2I-2fiqA:
17.54
4dr2J-2fiqA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		4 / 7 GLY A 281
VAL A 280
ILE A  43
PHE A  64
 None
 0.88A 4fglC-2fiqA:
undetectable		 4fglC-2fiqA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		5 / 12 LEU A 123
LEU A  89
GLY A  90
MET A 103
MET A 127
 None
 1.04A 4olmA-2fiqA:
undetectable		 4olmA-2fiqA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		4 / 8 ILE A 407
LEU A  42
LEU A  31
ILE A  82
 None
 0.76A 4r38A-2fiqA:
undetectable		 4r38A-2fiqA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		4 / 8 ILE A 407
LEU A  42
LEU A  31
ILE A  82
 None
 0.77A 4r38D-2fiqA:
undetectable		 4r38D-2fiqA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		3 / 3 LEU A 411
ARG A 412
ARG A 415
 None
 0.97A 4yiaB-2fiqA:
undetectable		 4yiaB-2fiqA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		5 / 12 ILE A 349
HIS A 355
VAL A 318
VAL A 314
TYR A 330
 None
 1.14A 5n0sB-2fiqA:
undetectable		 5n0sB-2fiqA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		3 / 3 MET A 103
GLU A 143
ARG A 144
 None
 0.77A 5tjyA-2fiqA:
2.4		 5tjyA-2fiqA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		3 / 3 MET A 103
GLU A 143
ARG A 144
 None
 0.72A 5tjzA-2fiqA:
2.4		 5tjzA-2fiqA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1
(Escherichia
coli) 		3 / 3 ARG A 415
LYS A 385
ARG A  39
 None
 1.43A 6az3C-2fiqA:
0.0
6az3L-2fiqA:
0.0
6az3M-2fiqA:
0.0		 6az3C-2fiqA:
10.92
6az3L-2fiqA:
9.88
6az3M-2fiqA:
10.73