SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2fj3 MAJOR PRION PROTEIN
(Oryctolagus
cuniculus) 		3 / 3 ASP A 146
ARG A 147
ARG A 150
 None
 0.95A 2j9dA-2fj3A:
undetectable
2j9dC-2fj3A:
undetectable		 2j9dA-2fj3A:
19.42
2j9dC-2fj3A:
19.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 2fj3 MAJOR PRION PROTEIN
(Oryctolagus
cuniculus) 		4 / 8 TYR A 161
ILE A 181
GLN A 185
THR A 190
 None
 0.77A 4ma7A-2fj3A:
11.5		 4ma7A-2fj3A:
89.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2fj3 MAJOR PRION PROTEIN
(Oryctolagus
cuniculus) 		3 / 3 GLY A 141
ASP A 146
ASN A 152
 None
 0.61A 5jglA-2fj3A:
undetectable		 5jglA-2fj3A:
17.56