SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fja'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 11 GLY A 118
HIS A 115
ALA B 832
ILE B 837
GLY A 456
 None
 1.09A 1c9sP-2fjaA:
undetectable
1c9sQ-2fjaA:
undetectable		 1c9sP-2fjaA:
7.47
1c9sQ-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 GLY A 456
GLY A 118
HIS A 115
ALA B 832
ILE B 837
 None
 1.10A 1gtfJ-2fjaA:
undetectable
1gtfK-2fjaA:
undetectable		 1gtfJ-2fjaA:
7.47
1gtfK-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 11 GLY A 118
HIS A 115
ALA B 832
ILE B 837
GLY A 456
 None
 1.08A 1gtfQ-2fjaA:
undetectable
1gtfR-2fjaA:
undetectable		 1gtfQ-2fjaA:
7.47
1gtfR-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 11 GLY A 118
HIS A 115
ALA B 832
ILE B 837
GLY A 456
 None
 1.08A 1gtfS-2fjaA:
undetectable
1gtfT-2fjaA:
undetectable		 1gtfS-2fjaA:
7.47
1gtfT-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 11 GLY A 118
HIS A 115
ALA B 832
ILE B 837
GLY A 456
 None
 1.05A 1gtnT-2fjaA:
undetectable
1gtnU-2fjaA:
undetectable		 1gtnT-2fjaA:
7.47
1gtnU-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 11 ILE A 156
GLY A  69
ARG A  62
GLY A 150
PHE A  32
 None
 0.98A 1ho5A-2fjaA:
undetectable		 1ho5A-2fjaA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 9 LEU A 212
GLY A 191
VAL A  55
GLY A 194
ILE A  28
 None
 0.96A 1hpvA-2fjaA:
undetectable		 1hpvA-2fjaA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 8 MET B 756
PRO B 779
MET B 787
TRP B 788
 None
 1.01A 1hrkA-2fjaB:
undetectable		 1hrkA-2fjaB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 8 MET B 756
PRO B 779
MET B 787
TRP B 788
 None
 0.97A 1hrkB-2fjaB:
undetectable		 1hrkB-2fjaB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 VAL A  96
ASP A  99
ASP A 107
THR A 255
GLY A 400
 None
 1.41A 1ia0B-2fjaA:
undetectable		 1ia0B-2fjaA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.42A 1k2sA-2fjaB:
undetectable
1k2sB-2fjaB:
undetectable		 1k2sA-2fjaB:
18.14
1k2sB-2fjaB:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 1k2tA-2fjaA:
undetectable
1k2tB-2fjaA:
undetectable		 1k2tA-2fjaA:
23.16
1k2tB-2fjaA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 1k2tA-2fjaB:
undetectable
1k2tB-2fjaB:
undetectable		 1k2tA-2fjaB:
18.14
1k2tB-2fjaB:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.36A 1k2uA-2fjaA:
undetectable
1k2uB-2fjaA:
undetectable		 1k2uA-2fjaA:
23.16
1k2uB-2fjaA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 PHE A 257
ALA A 583
ALA A 581
TYR A 245
LEU A 557
 None
 1.33A 1kt5A-2fjaA:
undetectable		 1kt5A-2fjaA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 10 GLY A  31
VAL A  60
ALA A  37
ALA A  38
ILE A  27
 FAD  A1000 (-3.2A)
None
None
None
None
 1.00A 1likA-2fjaA:
3.5		 1likA-2fjaA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.39A 1lzxA-2fjaB:
undetectable
1lzxB-2fjaB:
undetectable		 1lzxA-2fjaB:
18.14
1lzxB-2fjaB:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.33A 1lzzA-2fjaA:
0.5
1lzzB-2fjaA:
undetectable		 1lzzA-2fjaA:
23.16
1lzzB-2fjaA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 1lzzA-2fjaA:
0.5
1lzzB-2fjaA:
undetectable		 1lzzA-2fjaA:
23.16
1lzzB-2fjaA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.40A 1m00A-2fjaA:
undetectable
1m00B-2fjaA:
undetectable		 1m00A-2fjaA:
23.16
1m00B-2fjaA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 1m00A-2fjaB:
undetectable
1m00B-2fjaB:
undetectable		 1m00A-2fjaB:
18.14
1m00B-2fjaB:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.35A 1mmvA-2fjaA:
undetectable
1mmvB-2fjaA:
undetectable		 1mmvA-2fjaA:
23.16
1mmvB-2fjaA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 1mmvA-2fjaA:
undetectable
1mmvB-2fjaA:
undetectable		 1mmvA-2fjaA:
23.16
1mmvB-2fjaA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.40A 1mmvA-2fjaB:
undetectable
1mmvB-2fjaB:
undetectable		 1mmvA-2fjaB:
18.14
1mmvB-2fjaB:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		3 / 3 PHE A 590
TRP A 613
GLU A 593
 None
 0.98A 1mogA-2fjaA:
undetectable		 1mogA-2fjaA:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 396
GLY A 403
ILE A 394
PHE A 448
ALA A 443
 None
 1.06A 1nv8B-2fjaA:
undetectable		 1nv8B-2fjaA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 ARG A 317
HIS A 398
SER A 399
TYR A 599
 None
 1.10A 1nx9A-2fjaA:
undetectable		 1nx9A-2fjaA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 ARG A 317
HIS A 398
SER A 399
TYR A 599
 None
 1.11A 1nx9B-2fjaA:
undetectable		 1nx9B-2fjaA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 ARG A 317
HIS A 398
SER A 399
TYR A 599
 None
 1.13A 1nx9C-2fjaA:
undetectable		 1nx9C-2fjaA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 ARG A 317
HIS A 398
SER A 399
TYR A 599
 None
 1.12A 1nx9D-2fjaA:
undetectable		 1nx9D-2fjaA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OAF_A_ASCA1253_0
(ASCORBATE PEROXIDASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 LYS A   2
PRO A 514
LEU A 518
ARG A 577
 None
 1.43A 1oafA-2fjaA:
0.0		 1oafA-2fjaA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OAF_A_ASCA1253_0
(ASCORBATE PEROXIDASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		4 / 6 CYH B 747
PRO B 744
HIS A 566
ARG A 570
 SF4  B1100 (-2.4A)
None
None
None
 1.44A 1oafA-2fjaB:
0.0		 1oafA-2fjaB:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 1om4A-2fjaA:
0.5
1om4B-2fjaA:
undetectable		 1om4A-2fjaA:
22.29
1om4B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.33A 1om4A-2fjaA:
0.5
1om4B-2fjaA:
undetectable		 1om4A-2fjaA:
22.29
1om4B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 1om4A-2fjaB:
undetectable
1om4B-2fjaB:
undetectable		 1om4A-2fjaB:
18.25
1om4B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 1om5A-2fjaB:
undetectable
1om5B-2fjaB:
undetectable		 1om5A-2fjaB:
18.53
1om5B-2fjaB:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		4 / 7 ILE B 724
PRO B 726
PHE A 238
ALA A  67
 None
 1.11A 1oniG-2fjaB:
undetectable
1oniI-2fjaB:
undetectable		 1oniG-2fjaB:
19.38
1oniI-2fjaB:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.31A 1p6jA-2fjaA:
undetectable
1p6jB-2fjaA:
undetectable		 1p6jA-2fjaA:
23.32
1p6jB-2fjaA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 1p6jA-2fjaA:
undetectable
1p6jB-2fjaA:
undetectable		 1p6jA-2fjaA:
23.32
1p6jB-2fjaA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.39A 1p6jA-2fjaB:
undetectable
1p6jB-2fjaB:
undetectable		 1p6jA-2fjaB:
18.53
1p6jB-2fjaB:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 1p6kA-2fjaA:
0.5
1p6kB-2fjaA:
undetectable		 1p6kA-2fjaA:
23.32
1p6kB-2fjaA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 1p6kA-2fjaB:
undetectable
1p6kB-2fjaB:
undetectable		 1p6kA-2fjaB:
18.53
1p6kB-2fjaB:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 8 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.39A 1rs6A-2fjaB:
undetectable
1rs6B-2fjaB:
undetectable		 1rs6A-2fjaB:
18.53
1rs6B-2fjaB:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.32A 1rs7A-2fjaA:
undetectable
1rs7B-2fjaA:
undetectable		 1rs7A-2fjaA:
23.32
1rs7B-2fjaA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 1rs7A-2fjaB:
undetectable
1rs7B-2fjaB:
undetectable		 1rs7A-2fjaB:
18.53
1rs7B-2fjaB:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 8 ALA A  37
GLY A  30
GLY A  29
ILE A  28
ALA A 441
 None
FAD  A1000 (-4.3A)
FAD  A1000 (-3.3A)
None
None
 0.98A 1sguA-2fjaA:
undetectable		 1sguA-2fjaA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 8 ALA A  38
GLY A  30
GLY A  29
ILE A  28
ALA A 459
 None
FAD  A1000 (-4.3A)
FAD  A1000 (-3.3A)
None
None
 1.31A 1sguA-2fjaA:
undetectable		 1sguA-2fjaA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 VAL A  96
ASP A  99
ASP A 107
THR A 255
GLY A 400
 None
 1.41A 1tubB-2fjaA:
undetectable		 1tubB-2fjaA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 573
HIS A 566
LEU B 729
ILE A 237
 None
None
SF4  B1100 ( 4.3A)
None
 1.16A 1tuvA-2fjaA:
undetectable		 1tuvA-2fjaA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 GLY A 118
HIS A 115
ALA B 832
ILE B 837
GLY A 456
 None
 1.12A 1utdE-2fjaA:
undetectable
1utdF-2fjaA:
undetectable		 1utdE-2fjaA:
7.47
1utdF-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 GLY A 118
HIS A 115
ALA B 832
ILE B 837
GLY A 456
 None
 1.12A 1utdH-2fjaA:
undetectable
1utdI-2fjaA:
undetectable		 1utdH-2fjaA:
7.47
1utdI-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 11 GLY A 118
HIS A 115
ALA B 832
ILE B 837
GLY A 456
 None
 1.07A 1utdS-2fjaA:
undetectable
1utdT-2fjaA:
undetectable		 1utdS-2fjaA:
7.47
1utdT-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 11 GLY A 456
GLY A 118
HIS A 115
ALA B 832
ILE B 837
 None
 1.04A 1utdL-2fjaA:
undetectable
1utdV-2fjaA:
undetectable		 1utdL-2fjaA:
7.47
1utdV-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		3 / 3 ARG A 265
SER B 752
TYR B 751
 None
SF4  B1100 ( 4.5A)
None
 0.46A 1x70A-2fjaA:
undetectable		 1x70A-2fjaA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.35A 1zzqA-2fjaA:
undetectable
1zzqB-2fjaA:
undetectable		 1zzqA-2fjaA:
22.14
1zzqB-2fjaA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.40A 1zzqA-2fjaA:
undetectable
1zzqB-2fjaA:
undetectable		 1zzqA-2fjaA:
22.14
1zzqB-2fjaA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 1zzqA-2fjaB:
undetectable
1zzqB-2fjaB:
undetectable		 1zzqA-2fjaB:
17.86
1zzqB-2fjaB:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 9 ILE A 211
GLY A 456
GLU A 455
ALA A 459
THR A 429
 None
 1.24A 2dtjA-2fjaA:
undetectable
2dtjB-2fjaA:
undetectable		 2dtjA-2fjaA:
15.74
2dtjB-2fjaA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 10 PHE A 448
TYR A 112
GLU A 401
GLY A 442
ALA A 443
 None
 1.09A 2ej3B-2fjaA:
undetectable		 2ej3B-2fjaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.90A 2f81A-2fjaA:
undetectable		 2f81A-2fjaA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 2g6hA-2fjaB:
undetectable
2g6hB-2fjaB:
undetectable		 2g6hA-2fjaB:
17.86
2g6hB-2fjaB:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 2g6kA-2fjaB:
undetectable
2g6kB-2fjaB:
undetectable		 2g6kA-2fjaB:
17.86
2g6kB-2fjaB:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 2g6mA-2fjaB:
undetectable
2g6mB-2fjaB:
undetectable		 2g6mA-2fjaB:
17.86
2g6mB-2fjaB:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 8 GLY A  34
GLY A  36
ALA A  38
ALA A  37
PHE A 453
 None
 1.16A 2ha4A-2fjaA:
undetectable		 2ha4A-2fjaA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 8 GLY A  34
GLY A  36
ALA A 161
ALA A  38
PHE A 453
 None
 1.46A 2ha4A-2fjaA:
undetectable		 2ha4A-2fjaA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 7 GLY A  34
GLY A  36
ALA A  38
ALA A  37
PHE A 453
 None
 1.12A 2ha4B-2fjaA:
undetectable		 2ha4B-2fjaA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 7 GLY A  34
GLY A  36
ALA A 161
ALA A  38
PHE A 453
 None
 1.43A 2ha4B-2fjaA:
undetectable		 2ha4B-2fjaA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 MET B 756
PRO B 779
MET B 787
TRP B 788
 None
 1.05A 2hrcA-2fjaB:
undetectable		 2hrcA-2fjaB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.76A 2hs2A-2fjaA:
undetectable		 2hs2A-2fjaA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 2hx3A-2fjaB:
undetectable
2hx3B-2fjaB:
undetectable		 2hx3A-2fjaB:
18.25
2hx3B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 2hx4A-2fjaA:
undetectable
2hx4B-2fjaA:
undetectable		 2hx4A-2fjaA:
22.29
2hx4B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 2hx4A-2fjaB:
undetectable
2hx4B-2fjaB:
undetectable		 2hx4A-2fjaB:
18.25
2hx4B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.93A 2ienA-2fjaA:
undetectable		 2ienA-2fjaA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 ALA A 460
ALA A 209
GLY A  34
GLY A 456
TYR A 171
 None
 1.08A 2igtA-2fjaA:
undetectable		 2igtA-2fjaA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 PHE A 205
ALA A  41
GLY A  34
GLY A 456
TYR A 171
 None
 1.15A 2igtA-2fjaA:
undetectable		 2igtA-2fjaA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 ALA A 460
ALA A 209
GLY A  34
GLY A 456
TYR A 171
 None
 1.07A 2igtB-2fjaA:
undetectable		 2igtB-2fjaA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 5 MET B 756
PRO B 779
MET B 787
TRP B 788
 None
 1.06A 2pnjA-2fjaB:
undetectable		 2pnjA-2fjaB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 MET B 756
PRO B 779
MET B 787
TRP B 788
 None
 1.03A 2pnjB-2fjaB:
undetectable		 2pnjB-2fjaB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.91A 2q63B-2fjaA:
undetectable		 2q63B-2fjaA:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.91A 2qakB-2fjaA:
undetectable		 2qakB-2fjaA:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 11 LEU A 212
ILE A  28
GLY A  29
GLY A  34
LEU A 434
 None
None
FAD  A1000 (-3.3A)
None
None
 0.97A 2qmmA-2fjaA:
undetectable
2qmmB-2fjaA:
2.4		 2qmmA-2fjaA:
16.83
2qmmB-2fjaA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 TYR A 245
PRO A 491
ALA A 571
LEU A 568
 None
 0.97A 2vcvA-2fjaA:
undetectable		 2vcvA-2fjaA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 PRO A 514
ALA A 562
LEU A 560
PHE A 177
 None
 0.97A 2vcvL-2fjaA:
undetectable		 2vcvL-2fjaA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 SER A  83
VAL A 120
ILE A 146
ASP A  78
 None
 1.06A 2x45B-2fjaA:
undetectable		 2x45B-2fjaA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 SER A  83
VAL A 120
ILE A 146
ASP A  78
 None
 1.06A 2x45C-2fjaA:
undetectable		 2x45C-2fjaA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 396
GLY A 400
ALA A 443
ALA A 441
ARG A 427
 None
 0.99A 2yqzA-2fjaA:
undetectable		 2yqzA-2fjaA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 THR A  75
ILE A  73
ALA A 110
VAL A 109
ASP A 117
 None
 1.08A 2yvlB-2fjaA:
2.5		 2yvlB-2fjaA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA2_0
(FERROCHELATASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 MET B 756
PRO B 779
MET B 787
TRP B 788
 None
 1.04A 3aqiA-2fjaB:
undetectable		 3aqiA-2fjaB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB4_0
(FERROCHELATASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 MET B 756
PRO B 779
MET B 787
TRP B 788
 None
 0.99A 3aqiB-2fjaB:
undetectable		 3aqiB-2fjaB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.34A 3b3mA-2fjaA:
undetectable
3b3mB-2fjaA:
undetectable		 3b3mA-2fjaA:
22.29
3b3mB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.41A 3b3mA-2fjaA:
undetectable
3b3mB-2fjaA:
undetectable		 3b3mA-2fjaA:
22.29
3b3mB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 3b3mA-2fjaB:
undetectable
3b3mB-2fjaB:
undetectable		 3b3mA-2fjaB:
18.25
3b3mB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 3b3nA-2fjaA:
undetectable
3b3nB-2fjaA:
undetectable		 3b3nA-2fjaA:
22.29
3b3nB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 3b3nA-2fjaB:
undetectable
3b3nB-2fjaB:
undetectable		 3b3nA-2fjaB:
18.25
3b3nB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 3b3oA-2fjaA:
undetectable
3b3oB-2fjaA:
undetectable		 3b3oA-2fjaA:
22.29
3b3oB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.32A 3b3oA-2fjaA:
undetectable
3b3oB-2fjaA:
undetectable		 3b3oA-2fjaA:
22.29
3b3oB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 3b3oA-2fjaB:
undetectable
3b3oB-2fjaB:
undetectable		 3b3oA-2fjaB:
18.25
3b3oB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.40A 3b3pA-2fjaA:
undetectable
3b3pB-2fjaA:
1.5		 3b3pA-2fjaA:
22.29
3b3pB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 8 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 3b3pA-2fjaB:
undetectable
3b3pB-2fjaB:
undetectable		 3b3pA-2fjaB:
18.25
3b3pB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 SER A  83
VAL A 120
ILE A 146
ASP A  78
 None
 0.90A 3bu1A-2fjaA:
undetectable		 3bu1A-2fjaA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.83A 3cyxA-2fjaA:
undetectable		 3cyxA-2fjaA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.89A 3d20A-2fjaA:
undetectable		 3d20A-2fjaA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 PRO A 315
GLY A 400
GLY A 403
LEU A 254
HIS A 584
 None
 1.11A 3e23A-2fjaA:
2.2		 3e23A-2fjaA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 8 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.96A 3ekpA-2fjaA:
undetectable		 3ekpA-2fjaA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 11 GLY A 456
GLY A  36
PHE A  32
ALA A 462
ALA A 213
 None
 1.02A 3g88A-2fjaA:
undetectable		 3g88A-2fjaA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 11 GLY A 456
GLY A  36
PHE A  32
ALA A 462
ALA A 213
 None
 1.03A 3g88B-2fjaA:
undetectable		 3g88B-2fjaA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 456
GLY A  36
PHE A  32
ALA A 462
ALA A 213
 None
 1.05A 3g89A-2fjaA:
undetectable		 3g89A-2fjaA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 11 GLY A 456
GLY A  36
PHE A  32
ALA A 462
ALA A 213
 None
 1.06A 3g89B-2fjaA:
undetectable		 3g89B-2fjaA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 456
GLY A  36
PHE A  32
ALA A 462
ALA A 213
 None
 1.06A 3g8bA-2fjaA:
undetectable		 3g8bA-2fjaA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 456
GLY A  36
PHE A  32
ALA A 462
ALA A 213
 None
 1.03A 3g8bB-2fjaA:
undetectable		 3g8bB-2fjaA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 3hsnA-2fjaA:
undetectable
3hsnB-2fjaA:
undetectable		 3hsnA-2fjaA:
22.29
3hsnB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 3hsnA-2fjaB:
undetectable
3hsnB-2fjaB:
undetectable		 3hsnA-2fjaB:
18.25
3hsnB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 3hsoA-2fjaA:
undetectable
3hsoB-2fjaA:
undetectable		 3hsoA-2fjaA:
22.29
3hsoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 3hsoA-2fjaB:
undetectable
3hsoB-2fjaB:
undetectable		 3hsoA-2fjaB:
18.25
3hsoB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 3hspA-2fjaA:
undetectable
3hspB-2fjaA:
undetectable		 3hspA-2fjaA:
22.29
3hspB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3jt3A-2fjaA:
undetectable
3jt3B-2fjaA:
undetectable		 3jt3A-2fjaA:
22.29
3jt3B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 3jt3A-2fjaA:
undetectable
3jt3B-2fjaA:
undetectable		 3jt3A-2fjaA:
22.29
3jt3B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 3jt3A-2fjaB:
undetectable
3jt3B-2fjaB:
undetectable		 3jt3A-2fjaB:
18.25
3jt3B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.30A 3jt4A-2fjaA:
undetectable
3jt4B-2fjaA:
undetectable		 3jt4A-2fjaA:
22.29
3jt4B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3jt4A-2fjaA:
undetectable
3jt4B-2fjaA:
undetectable		 3jt4A-2fjaA:
22.29
3jt4B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 3jt4A-2fjaA:
undetectable
3jt4B-2fjaA:
undetectable		 3jt4A-2fjaA:
22.29
3jt4B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 3jt4A-2fjaB:
undetectable
3jt4B-2fjaB:
undetectable		 3jt4A-2fjaB:
18.25
3jt4B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3jt5A-2fjaA:
undetectable
3jt5B-2fjaA:
undetectable		 3jt5A-2fjaA:
22.29
3jt5B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 3jt5A-2fjaB:
undetectable
3jt5B-2fjaB:
undetectable		 3jt5A-2fjaB:
18.25
3jt5B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.40A 3jt6A-2fjaA:
undetectable
3jt6B-2fjaA:
undetectable		 3jt6A-2fjaA:
22.29
3jt6B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3jt7A-2fjaA:
undetectable
3jt7B-2fjaA:
undetectable		 3jt7A-2fjaA:
22.29
3jt7B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 3jt7A-2fjaB:
undetectable
3jt7B-2fjaB:
undetectable		 3jt7A-2fjaB:
18.25
3jt7B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.32A 3jt8A-2fjaA:
undetectable
3jt8B-2fjaA:
undetectable		 3jt8A-2fjaA:
22.29
3jt8B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3jt8A-2fjaA:
undetectable
3jt8B-2fjaA:
undetectable		 3jt8A-2fjaA:
22.29
3jt8B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 3jt8A-2fjaB:
undetectable
3jt8B-2fjaB:
undetectable		 3jt8A-2fjaB:
18.25
3jt8B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 3jt9A-2fjaB:
undetectable
3jt9B-2fjaB:
undetectable		 3jt9A-2fjaB:
18.25
3jt9B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 3jwsA-2fjaA:
undetectable
3jwsB-2fjaA:
undetectable		 3jwsA-2fjaA:
21.87
3jwsB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 3jwsA-2fjaB:
undetectable
3jwsB-2fjaB:
undetectable		 3jwsA-2fjaB:
18.25
3jwsB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.26A 3jwtA-2fjaA:
undetectable
3jwtB-2fjaA:
undetectable		 3jwtA-2fjaA:
21.87
3jwtB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 3jwtA-2fjaA:
undetectable
3jwtB-2fjaA:
undetectable		 3jwtA-2fjaA:
21.87
3jwtB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.25A 3jwtA-2fjaA:
undetectable
3jwtB-2fjaA:
undetectable		 3jwtA-2fjaA:
21.87
3jwtB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 3jwtA-2fjaB:
undetectable
3jwtB-2fjaB:
undetectable		 3jwtA-2fjaB:
18.25
3jwtB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.20A 3jwuA-2fjaA:
undetectable
3jwuB-2fjaA:
undetectable		 3jwuA-2fjaA:
21.87
3jwuB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 3jwuA-2fjaA:
undetectable
3jwuB-2fjaA:
undetectable		 3jwuA-2fjaA:
21.87
3jwuB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 3jwuA-2fjaB:
undetectable
3jwuB-2fjaB:
undetectable		 3jwuA-2fjaB:
18.25
3jwuB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.17A 3jwvA-2fjaA:
undetectable
3jwvB-2fjaA:
undetectable		 3jwvA-2fjaA:
21.87
3jwvB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 3jwvA-2fjaA:
undetectable
3jwvB-2fjaA:
undetectable		 3jwvA-2fjaA:
21.87
3jwvB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.23A 3jwvA-2fjaA:
undetectable
3jwvB-2fjaA:
undetectable		 3jwvA-2fjaA:
21.87
3jwvB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 3jwvA-2fjaB:
undetectable
3jwvB-2fjaB:
undetectable		 3jwvA-2fjaB:
18.25
3jwvB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3jx0A-2fjaA:
undetectable
3jx0B-2fjaA:
undetectable		 3jx0A-2fjaA:
22.29
3jx0B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.26A 3jx1A-2fjaA:
undetectable
3jx1B-2fjaA:
undetectable		 3jx1A-2fjaA:
22.29
3jx1B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.31A 3jx1A-2fjaA:
undetectable
3jx1B-2fjaA:
undetectable		 3jx1A-2fjaA:
22.29
3jx1B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.26A 3jx3A-2fjaA:
0.5
3jx3B-2fjaA:
undetectable		 3jx3A-2fjaA:
22.29
3jx3B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.27A 3jx3A-2fjaA:
0.5
3jx3B-2fjaA:
undetectable		 3jx3A-2fjaA:
22.29
3jx3B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.17A 3jx6A-2fjaA:
0.5
3jx6B-2fjaA:
0.6		 3jx6A-2fjaA:
22.29
3jx6B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.24A 3jx6A-2fjaA:
0.5
3jx6B-2fjaA:
0.6		 3jx6A-2fjaA:
22.29
3jx6B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		3 / 3 ARG A 563
ASP B 745
GLN A 522
 None
 0.93A 3lcvB-2fjaA:
undetectable		 3lcvB-2fjaA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.30A 3n2rA-2fjaA:
undetectable
3n2rB-2fjaA:
undetectable		 3n2rA-2fjaA:
22.29
3n2rB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 3n2rA-2fjaA:
undetectable
3n2rB-2fjaA:
undetectable		 3n2rA-2fjaA:
22.29
3n2rB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.33A 3n2rA-2fjaA:
undetectable
3n2rB-2fjaA:
undetectable		 3n2rA-2fjaA:
22.29
3n2rB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 3n2rA-2fjaB:
undetectable
3n2rB-2fjaB:
undetectable		 3n2rA-2fjaB:
18.25
3n2rB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.15A 3n5vA-2fjaA:
undetectable
3n5vB-2fjaA:
undetectable		 3n5vA-2fjaA:
22.29
3n5vB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.46A 3n5vA-2fjaA:
undetectable
3n5vB-2fjaA:
undetectable		 3n5vA-2fjaA:
22.29
3n5vB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.18A 3n5vA-2fjaA:
undetectable
3n5vB-2fjaA:
undetectable		 3n5vA-2fjaA:
22.29
3n5vB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 3n5vA-2fjaB:
undetectable
3n5vB-2fjaB:
undetectable		 3n5vA-2fjaB:
18.25
3n5vB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.19A 3n5yA-2fjaA:
0.5
3n5yB-2fjaA:
undetectable		 3n5yA-2fjaA:
22.29
3n5yB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.40A 3n5yA-2fjaA:
0.5
3n5yB-2fjaA:
undetectable		 3n5yA-2fjaA:
22.29
3n5yB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.26A 3n5yA-2fjaA:
0.5
3n5yB-2fjaA:
undetectable		 3n5yA-2fjaA:
22.29
3n5yB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 3n5yA-2fjaB:
undetectable
3n5yB-2fjaB:
undetectable		 3n5yA-2fjaB:
18.25
3n5yB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.18A 3n5zA-2fjaA:
undetectable
3n5zB-2fjaA:
0.5		 3n5zA-2fjaA:
22.29
3n5zB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3n5zA-2fjaA:
undetectable
3n5zB-2fjaA:
0.5		 3n5zA-2fjaA:
22.29
3n5zB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.25A 3n5zA-2fjaA:
undetectable
3n5zB-2fjaA:
0.5		 3n5zA-2fjaA:
22.29
3n5zB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 3n5zA-2fjaB:
undetectable
3n5zB-2fjaB:
undetectable		 3n5zA-2fjaB:
18.25
3n5zB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 521
PHE A 257
ILE A 394
GLY A 216
ALA A 217
 None
 1.08A 3n8xB-2fjaA:
undetectable		 3n8xB-2fjaA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.23A 3nljA-2fjaA:
undetectable
3nljB-2fjaA:
undetectable		 3nljA-2fjaA:
22.29
3nljB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.23A 3nljA-2fjaA:
undetectable
3nljB-2fjaA:
undetectable		 3nljA-2fjaA:
22.29
3nljB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.30A 3nljA-2fjaB:
undetectable
3nljB-2fjaB:
undetectable		 3nljA-2fjaB:
18.25
3nljB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.25A 3nlkA-2fjaA:
undetectable
3nlkB-2fjaA:
undetectable		 3nlkA-2fjaA:
21.87
3nlkB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.33A 3nlkA-2fjaA:
undetectable
3nlkB-2fjaA:
undetectable		 3nlkA-2fjaA:
21.87
3nlkB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.23A 3nlkA-2fjaA:
undetectable
3nlkB-2fjaA:
undetectable		 3nlkA-2fjaA:
21.87
3nlkB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 3nlkA-2fjaB:
undetectable
3nlkB-2fjaB:
undetectable		 3nlkA-2fjaB:
18.25
3nlkB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.29A 3nlmA-2fjaA:
undetectable
3nlmB-2fjaA:
undetectable		 3nlmA-2fjaA:
22.29
3nlmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 3nlmA-2fjaA:
undetectable
3nlmB-2fjaA:
undetectable		 3nlmA-2fjaA:
22.29
3nlmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 3nlmA-2fjaA:
undetectable
3nlmB-2fjaA:
undetectable		 3nlmA-2fjaA:
22.29
3nlmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.24A 3nlnA-2fjaA:
undetectable
3nlnB-2fjaA:
undetectable		 3nlnA-2fjaA:
21.87
3nlnB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 3nlnA-2fjaA:
undetectable
3nlnB-2fjaA:
undetectable		 3nlnA-2fjaA:
21.87
3nlnB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 3nlnA-2fjaB:
undetectable
3nlnB-2fjaB:
undetectable		 3nlnA-2fjaB:
18.25
3nlnB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 3nloA-2fjaA:
undetectable
3nloB-2fjaA:
undetectable		 3nloA-2fjaA:
21.87
3nloB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.27A 3nloA-2fjaA:
undetectable
3nloB-2fjaA:
undetectable		 3nloA-2fjaA:
21.87
3nloB-2fjaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 3nloA-2fjaB:
undetectable
3nloB-2fjaB:
undetectable		 3nloA-2fjaB:
18.25
3nloB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.26A 3nlvA-2fjaA:
undetectable
3nlvB-2fjaA:
undetectable		 3nlvA-2fjaA:
22.29
3nlvB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 3nlvA-2fjaA:
undetectable
3nlvB-2fjaA:
undetectable		 3nlvA-2fjaA:
22.29
3nlvB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 3nlvA-2fjaA:
undetectable
3nlvB-2fjaA:
undetectable		 3nlvA-2fjaA:
22.29
3nlvB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 3nlvA-2fjaB:
undetectable
3nlvB-2fjaB:
undetectable		 3nlvA-2fjaB:
18.25
3nlvB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.26A 3nlwA-2fjaA:
undetectable
3nlwB-2fjaA:
undetectable		 3nlwA-2fjaA:
22.29
3nlwB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 3nlwA-2fjaA:
undetectable
3nlwB-2fjaA:
undetectable		 3nlwA-2fjaA:
22.29
3nlwB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.31A 3nlwA-2fjaA:
undetectable
3nlwB-2fjaA:
undetectable		 3nlwA-2fjaA:
22.29
3nlwB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 3nlwA-2fjaB:
undetectable
3nlwB-2fjaB:
undetectable		 3nlwA-2fjaB:
18.25
3nlwB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.25A 3nlxA-2fjaA:
undetectable
3nlxB-2fjaA:
undetectable		 3nlxA-2fjaA:
22.29
3nlxB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3nlxA-2fjaA:
undetectable
3nlxB-2fjaA:
undetectable		 3nlxA-2fjaA:
22.29
3nlxB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.25A 3nlxA-2fjaA:
undetectable
3nlxB-2fjaA:
undetectable		 3nlxA-2fjaA:
22.29
3nlxB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 3nlxA-2fjaB:
undetectable
3nlxB-2fjaB:
undetectable		 3nlxA-2fjaB:
18.25
3nlxB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.20A 3nlyA-2fjaA:
undetectable
3nlyB-2fjaA:
undetectable		 3nlyA-2fjaA:
22.29
3nlyB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 3nlyA-2fjaA:
undetectable
3nlyB-2fjaA:
undetectable		 3nlyA-2fjaA:
22.29
3nlyB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.31A 3nlyA-2fjaA:
undetectable
3nlyB-2fjaA:
undetectable		 3nlyA-2fjaA:
22.29
3nlyB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 8 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 3nlyA-2fjaB:
undetectable
3nlyB-2fjaB:
undetectable		 3nlyA-2fjaB:
18.25
3nlyB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.27A 3nlzA-2fjaA:
undetectable
3nlzB-2fjaA:
undetectable		 3nlzA-2fjaA:
22.29
3nlzB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 3nlzA-2fjaA:
undetectable
3nlzB-2fjaA:
undetectable		 3nlzA-2fjaA:
22.29
3nlzB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.30A 3nlzA-2fjaA:
undetectable
3nlzB-2fjaA:
undetectable		 3nlzA-2fjaA:
22.29
3nlzB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.26A 3nm0A-2fjaA:
undetectable
3nm0B-2fjaA:
undetectable		 3nm0A-2fjaA:
22.29
3nm0B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 3nm0A-2fjaA:
undetectable
3nm0B-2fjaA:
undetectable		 3nm0A-2fjaA:
22.29
3nm0B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.26A 3nm0A-2fjaA:
undetectable
3nm0B-2fjaA:
undetectable		 3nm0A-2fjaA:
22.29
3nm0B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 3nm0A-2fjaB:
undetectable
3nm0B-2fjaB:
undetectable		 3nm0A-2fjaB:
18.25
3nm0B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.25A 3nnyA-2fjaA:
undetectable
3nnyB-2fjaA:
0.6		 3nnyA-2fjaA:
22.29
3nnyB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3nnyA-2fjaA:
undetectable
3nnyB-2fjaA:
0.6		 3nnyA-2fjaA:
22.29
3nnyB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.27A 3nnyA-2fjaA:
undetectable
3nnyB-2fjaA:
0.6		 3nnyA-2fjaA:
22.29
3nnyB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 3nnyA-2fjaB:
undetectable
3nnyB-2fjaB:
undetectable		 3nnyA-2fjaB:
18.25
3nnyB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.27A 3nnzA-2fjaA:
undetectable
3nnzB-2fjaA:
undetectable		 3nnzA-2fjaA:
22.29
3nnzB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 3nnzA-2fjaA:
undetectable
3nnzB-2fjaA:
undetectable		 3nnzA-2fjaA:
22.29
3nnzB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 3nnzA-2fjaA:
undetectable
3nnzB-2fjaA:
undetectable		 3nnzA-2fjaA:
22.29
3nnzB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 3nnzA-2fjaB:
undetectable
3nnzB-2fjaB:
undetectable		 3nnzA-2fjaB:
18.25
3nnzB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 9 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.90A 3nu4B-2fjaA:
undetectable		 3nu4B-2fjaA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.80A 3nu5A-2fjaA:
undetectable		 3nu5A-2fjaA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 9 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.95A 3oxvA-2fjaA:
undetectable		 3oxvA-2fjaA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 9 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.97A 3oxvC-2fjaA:
undetectable		 3oxvC-2fjaA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.25A 3pneA-2fjaA:
undetectable
3pneB-2fjaA:
undetectable		 3pneA-2fjaA:
22.29
3pneB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3pneA-2fjaA:
undetectable
3pneB-2fjaA:
undetectable		 3pneA-2fjaA:
22.29
3pneB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.27A 3pneA-2fjaA:
undetectable
3pneB-2fjaA:
undetectable		 3pneA-2fjaA:
22.29
3pneB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 3pneA-2fjaB:
undetectable
3pneB-2fjaB:
undetectable		 3pneA-2fjaB:
18.25
3pneB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.24A 3pnfA-2fjaA:
undetectable
3pnfB-2fjaA:
undetectable		 3pnfA-2fjaA:
22.29
3pnfB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 3pnfA-2fjaA:
undetectable
3pnfB-2fjaA:
undetectable		 3pnfA-2fjaA:
22.29
3pnfB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 3pnfA-2fjaA:
undetectable
3pnfB-2fjaA:
undetectable		 3pnfA-2fjaA:
22.29
3pnfB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 3pnfA-2fjaB:
undetectable
3pnfB-2fjaB:
undetectable		 3pnfA-2fjaB:
18.25
3pnfB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.30A 3pngA-2fjaA:
undetectable
3pngB-2fjaA:
undetectable		 3pngA-2fjaA:
22.29
3pngB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3pngA-2fjaA:
undetectable
3pngB-2fjaA:
undetectable		 3pngA-2fjaA:
22.29
3pngB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 3pngA-2fjaA:
undetectable
3pngB-2fjaA:
undetectable		 3pngA-2fjaA:
22.29
3pngB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 3pngA-2fjaB:
undetectable
3pngB-2fjaB:
undetectable		 3pngA-2fjaB:
18.25
3pngB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 3q99A-2fjaA:
undetectable
3q99B-2fjaA:
undetectable		 3q99A-2fjaA:
22.29
3q99B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.32A 3q99A-2fjaA:
undetectable
3q99B-2fjaA:
undetectable		 3q99A-2fjaA:
22.29
3q99B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.39A 3q9aA-2fjaB:
undetectable
3q9aB-2fjaB:
undetectable		 3q9aA-2fjaB:
18.25
3q9aB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		4 / 5 ASP A 564
HIS A 566
ARG B 742
GLU B 743
 None
 1.24A 3r4xA-2fjaA:
0.0		 3r4xA-2fjaA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.27A 3rqjA-2fjaA:
undetectable
3rqjB-2fjaA:
undetectable		 3rqjA-2fjaA:
22.29
3rqjB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3rqjA-2fjaA:
undetectable
3rqjB-2fjaA:
undetectable		 3rqjA-2fjaA:
22.29
3rqjB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.26A 3rqjA-2fjaA:
undetectable
3rqjB-2fjaA:
undetectable		 3rqjA-2fjaA:
22.29
3rqjB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 3rqjA-2fjaB:
undetectable
3rqjB-2fjaB:
undetectable		 3rqjA-2fjaB:
18.25
3rqjB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.30A 3rqkA-2fjaA:
undetectable
3rqkB-2fjaA:
undetectable		 3rqkA-2fjaA:
22.29
3rqkB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.32A 3rqkA-2fjaA:
undetectable
3rqkB-2fjaA:
undetectable		 3rqkA-2fjaA:
22.29
3rqkB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.31A 3rqlA-2fjaA:
undetectable
3rqlB-2fjaA:
undetectable		 3rqlA-2fjaA:
22.29
3rqlB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3rqlA-2fjaA:
undetectable
3rqlB-2fjaA:
undetectable		 3rqlA-2fjaA:
22.29
3rqlB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 3rqlA-2fjaA:
undetectable
3rqlB-2fjaA:
undetectable		 3rqlA-2fjaA:
22.29
3rqlB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 8 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 3rqlA-2fjaB:
undetectable
3rqlB-2fjaB:
undetectable		 3rqlA-2fjaB:
18.25
3rqlB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.27A 3rqmA-2fjaA:
undetectable
3rqmB-2fjaA:
undetectable		 3rqmA-2fjaA:
22.29
3rqmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3rqmA-2fjaA:
undetectable
3rqmB-2fjaA:
undetectable		 3rqmA-2fjaA:
22.29
3rqmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 3rqmA-2fjaA:
undetectable
3rqmB-2fjaA:
undetectable		 3rqmA-2fjaA:
22.29
3rqmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 3rqmA-2fjaB:
undetectable
3rqmB-2fjaB:
undetectable		 3rqmA-2fjaB:
18.25
3rqmB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.28A 3rqnA-2fjaA:
undetectable
3rqnB-2fjaA:
undetectable		 3rqnA-2fjaA:
22.29
3rqnB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3rqnA-2fjaA:
undetectable
3rqnB-2fjaA:
undetectable		 3rqnA-2fjaA:
22.29
3rqnB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.27A 3rqnA-2fjaA:
undetectable
3rqnB-2fjaA:
undetectable		 3rqnA-2fjaA:
22.29
3rqnB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 3rqnA-2fjaB:
undetectable
3rqnB-2fjaB:
undetectable		 3rqnA-2fjaB:
18.25
3rqnB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 5 ASP A 111
LEU A 108
ILE A 437
PHE A 435
 None
 1.22A 3s3vA-2fjaA:
undetectable		 3s3vA-2fjaA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.83A 3s54A-2fjaA:
undetectable		 3s54A-2fjaA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 LEU A 128
GLU A 159
PRO A 155
ILE A 156
 None
 0.87A 3s56B-2fjaA:
undetectable		 3s56B-2fjaA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 8 PRO B 844
HIS A 115
ILE B 838
ILE A  77
 None
 1.08A 3sfeB-2fjaB:
undetectable
3sfeC-2fjaB:
undetectable		 3sfeB-2fjaB:
22.61
3sfeC-2fjaB:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.26A 3svpA-2fjaA:
undetectable
3svpB-2fjaA:
undetectable		 3svpA-2fjaA:
22.29
3svpB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 3svpA-2fjaA:
undetectable
3svpB-2fjaA:
undetectable		 3svpA-2fjaA:
22.29
3svpB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 3svpA-2fjaB:
undetectable
3svpB-2fjaB:
undetectable		 3svpA-2fjaB:
18.25
3svpB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.30A 3svqA-2fjaA:
undetectable
3svqB-2fjaA:
undetectable		 3svqA-2fjaA:
22.29
3svqB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.30A 3tylA-2fjaA:
undetectable
3tylB-2fjaA:
undetectable		 3tylA-2fjaA:
22.29
3tylB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 3tylA-2fjaA:
undetectable
3tylB-2fjaA:
undetectable		 3tylA-2fjaA:
22.29
3tylB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.33A 3tylA-2fjaA:
undetectable
3tylB-2fjaA:
undetectable		 3tylA-2fjaA:
22.29
3tylB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 3tylA-2fjaB:
undetectable
3tylB-2fjaB:
undetectable		 3tylA-2fjaB:
18.25
3tylB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.28A 3tymA-2fjaA:
undetectable
3tymB-2fjaA:
undetectable		 3tymA-2fjaA:
22.29
3tymB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 3tymA-2fjaA:
undetectable
3tymB-2fjaA:
undetectable		 3tymA-2fjaA:
22.29
3tymB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.33A 3tymA-2fjaA:
0.5
3tymB-2fjaA:
undetectable		 3tymA-2fjaA:
22.29
3tymB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.29A 3tynA-2fjaA:
undetectable
3tynB-2fjaA:
undetectable		 3tynA-2fjaA:
22.29
3tynB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 3tynA-2fjaA:
undetectable
3tynB-2fjaA:
undetectable		 3tynA-2fjaA:
22.29
3tynB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 3tynA-2fjaA:
undetectable
3tynB-2fjaA:
undetectable		 3tynA-2fjaA:
22.29
3tynB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 3tynA-2fjaB:
undetectable
3tynB-2fjaB:
undetectable		 3tynA-2fjaB:
18.25
3tynB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.29A 3tyoA-2fjaA:
undetectable
3tyoB-2fjaA:
undetectable		 3tyoA-2fjaA:
22.29
3tyoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 3tyoA-2fjaA:
undetectable
3tyoB-2fjaA:
undetectable		 3tyoA-2fjaA:
22.29
3tyoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 3tyoA-2fjaA:
undetectable
3tyoB-2fjaA:
undetectable		 3tyoA-2fjaA:
22.29
3tyoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 3tyoA-2fjaB:
undetectable
3tyoB-2fjaB:
undetectable		 3tyoA-2fjaB:
18.25
3tyoB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 3ufoA-2fjaA:
undetectable
3ufoB-2fjaA:
undetectable		 3ufoA-2fjaA:
22.29
3ufoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.26A 3ufoA-2fjaA:
undetectable
3ufoB-2fjaA:
undetectable		 3ufoA-2fjaA:
22.29
3ufoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 3ufoA-2fjaB:
undetectable
3ufoB-2fjaB:
undetectable		 3ufoA-2fjaB:
18.25
3ufoB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 3ufpA-2fjaA:
undetectable
3ufpB-2fjaA:
undetectable		 3ufpA-2fjaA:
22.29
3ufpB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 3ufpA-2fjaB:
undetectable
3ufpB-2fjaB:
undetectable		 3ufpA-2fjaB:
18.25
3ufpB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 3ufqA-2fjaA:
undetectable
3ufqB-2fjaA:
undetectable		 3ufqA-2fjaA:
22.29
3ufqB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 3ufqA-2fjaB:
undetectable
3ufqB-2fjaB:
undetectable		 3ufqA-2fjaB:
18.25
3ufqB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.48A 3ufrA-2fjaA:
undetectable
3ufrB-2fjaA:
0.6		 3ufrA-2fjaA:
22.29
3ufrB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.26A 3ufrA-2fjaA:
undetectable
3ufrB-2fjaA:
0.6		 3ufrA-2fjaA:
22.29
3ufrB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.31A 3ufrA-2fjaB:
undetectable
3ufrB-2fjaB:
undetectable		 3ufrA-2fjaB:
18.25
3ufrB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.21A 3ufsA-2fjaA:
undetectable
3ufsB-2fjaA:
undetectable		 3ufsA-2fjaA:
22.29
3ufsB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 3ufsA-2fjaA:
undetectable
3ufsB-2fjaA:
undetectable		 3ufsA-2fjaA:
22.29
3ufsB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.27A 3ufsA-2fjaA:
undetectable
3ufsB-2fjaA:
undetectable		 3ufsA-2fjaA:
22.29
3ufsB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 3ufsA-2fjaB:
undetectable
3ufsB-2fjaB:
undetectable		 3ufsA-2fjaB:
18.25
3ufsB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.28A 3uftA-2fjaA:
undetectable
3uftB-2fjaA:
undetectable		 3uftA-2fjaA:
22.29
3uftB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 3uftA-2fjaB:
undetectable
3uftB-2fjaB:
undetectable		 3uftA-2fjaB:
18.25
3uftB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.26A 3ufuA-2fjaA:
undetectable
3ufuB-2fjaA:
undetectable		 3ufuA-2fjaA:
22.29
3ufuB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 3ufuA-2fjaA:
undetectable
3ufuB-2fjaA:
undetectable		 3ufuA-2fjaA:
22.29
3ufuB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.27A 3ufuA-2fjaA:
undetectable
3ufuB-2fjaA:
undetectable		 3ufuA-2fjaA:
22.29
3ufuB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 3ufuA-2fjaB:
undetectable
3ufuB-2fjaB:
undetectable		 3ufuA-2fjaB:
18.25
3ufuB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.27A 3ufvA-2fjaA:
0.5
3ufvB-2fjaA:
undetectable		 3ufvA-2fjaA:
22.29
3ufvB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 3ufvA-2fjaA:
0.5
3ufvB-2fjaA:
undetectable		 3ufvA-2fjaA:
22.29
3ufvB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.32A 3ufvA-2fjaA:
0.5
3ufvB-2fjaA:
undetectable		 3ufvA-2fjaA:
22.29
3ufvB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.29A 3ufwA-2fjaA:
0.5
3ufwB-2fjaA:
undetectable		 3ufwA-2fjaA:
22.29
3ufwB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.40A 3ufwA-2fjaA:
0.5
3ufwB-2fjaA:
undetectable		 3ufwA-2fjaA:
22.29
3ufwB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.31A 3ufwA-2fjaA:
0.5
3ufwB-2fjaA:
undetectable		 3ufwA-2fjaA:
22.29
3ufwB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 3ufwA-2fjaB:
undetectable
3ufwB-2fjaB:
undetectable		 3ufwA-2fjaB:
18.25
3ufwB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.26A 4c39A-2fjaA:
undetectable
4c39B-2fjaA:
undetectable		 4c39A-2fjaA:
22.29
4c39B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 4c39A-2fjaA:
undetectable
4c39B-2fjaA:
undetectable		 4c39A-2fjaA:
22.29
4c39B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 4c39A-2fjaB:
undetectable
4c39B-2fjaB:
undetectable		 4c39A-2fjaB:
18.25
4c39B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.25A 4camA-2fjaA:
undetectable
4camB-2fjaA:
undetectable		 4camA-2fjaA:
22.29
4camB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4camA-2fjaA:
undetectable
4camB-2fjaA:
undetectable		 4camA-2fjaA:
22.29
4camB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 4camA-2fjaB:
undetectable
4camB-2fjaB:
undetectable		 4camA-2fjaB:
18.25
4camB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 4canA-2fjaA:
undetectable
4canB-2fjaA:
undetectable		 4canA-2fjaA:
22.29
4canB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 4canA-2fjaB:
undetectable
4canB-2fjaB:
undetectable		 4canA-2fjaB:
18.25
4canB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.25A 4caoA-2fjaA:
undetectable
4caoB-2fjaA:
undetectable		 4caoA-2fjaA:
22.29
4caoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 4caoA-2fjaA:
undetectable
4caoB-2fjaA:
undetectable		 4caoA-2fjaA:
22.29
4caoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.27A 4caoA-2fjaA:
undetectable
4caoB-2fjaA:
undetectable		 4caoA-2fjaA:
22.29
4caoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 4caoA-2fjaB:
undetectable
4caoB-2fjaB:
undetectable		 4caoA-2fjaB:
18.25
4caoB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.27A 4capA-2fjaA:
undetectable
4capB-2fjaA:
undetectable		 4capA-2fjaA:
22.29
4capB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 4capA-2fjaA:
undetectable
4capB-2fjaA:
undetectable		 4capA-2fjaA:
22.29
4capB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.30A 4capA-2fjaA:
undetectable
4capB-2fjaA:
undetectable		 4capA-2fjaA:
22.29
4capB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 4caqA-2fjaA:
undetectable
4caqB-2fjaA:
0.5		 4caqA-2fjaA:
22.29
4caqB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 4caqA-2fjaB:
undetectable
4caqB-2fjaB:
undetectable		 4caqA-2fjaB:
18.25
4caqB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 4cdtA-2fjaA:
undetectable
4cdtB-2fjaA:
undetectable		 4cdtA-2fjaA:
22.29
4cdtB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 4cdtA-2fjaB:
undetectable
4cdtB-2fjaB:
undetectable		 4cdtA-2fjaB:
18.25
4cdtB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.25A 4ctpA-2fjaA:
0.5
4ctpB-2fjaA:
undetectable		 4ctpA-2fjaA:
22.29
4ctpB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4ctpA-2fjaA:
0.5
4ctpB-2fjaA:
undetectable		 4ctpA-2fjaA:
22.29
4ctpB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.30A 4ctpA-2fjaA:
0.5
4ctpB-2fjaA:
undetectable		 4ctpA-2fjaA:
22.29
4ctpB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 4ctpA-2fjaB:
undetectable
4ctpB-2fjaB:
undetectable		 4ctpA-2fjaB:
18.25
4ctpB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.28A 4ctqA-2fjaA:
0.6
4ctqB-2fjaA:
undetectable		 4ctqA-2fjaA:
22.29
4ctqB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4ctqA-2fjaA:
0.6
4ctqB-2fjaA:
undetectable		 4ctqA-2fjaA:
22.29
4ctqB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 4ctqA-2fjaA:
0.6
4ctqB-2fjaA:
undetectable		 4ctqA-2fjaA:
22.29
4ctqB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 4ctqA-2fjaB:
undetectable
4ctqB-2fjaB:
undetectable		 4ctqA-2fjaB:
18.25
4ctqB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.18A 4ctrA-2fjaA:
undetectable
4ctrB-2fjaA:
undetectable		 4ctrA-2fjaA:
22.29
4ctrB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 4ctrA-2fjaA:
undetectable
4ctrB-2fjaA:
undetectable		 4ctrA-2fjaA:
22.29
4ctrB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 4ctrA-2fjaA:
undetectable
4ctrB-2fjaA:
undetectable		 4ctrA-2fjaA:
22.29
4ctrB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 4ctrA-2fjaB:
undetectable
4ctrB-2fjaB:
undetectable		 4ctrA-2fjaB:
18.25
4ctrB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.21A 4cttA-2fjaA:
undetectable
4cttB-2fjaA:
undetectable		 4cttA-2fjaA:
22.29
4cttB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 4cttA-2fjaA:
undetectable
4cttB-2fjaA:
undetectable		 4cttA-2fjaA:
22.29
4cttB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 4cttA-2fjaB:
undetectable
4cttB-2fjaB:
undetectable		 4cttA-2fjaB:
18.25
4cttB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.28A 4ctuA-2fjaA:
undetectable
4ctuB-2fjaA:
0.6		 4ctuA-2fjaA:
22.29
4ctuB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4ctuA-2fjaA:
undetectable
4ctuB-2fjaA:
0.6		 4ctuA-2fjaA:
22.29
4ctuB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.28A 4ctvA-2fjaA:
0.5
4ctvB-2fjaA:
undetectable		 4ctvA-2fjaA:
22.29
4ctvB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 4ctvA-2fjaA:
0.5
4ctvB-2fjaA:
undetectable		 4ctvA-2fjaA:
22.29
4ctvB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.27A 4ctvA-2fjaA:
0.5
4ctvB-2fjaA:
undetectable		 4ctvA-2fjaA:
22.29
4ctvB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 4ctvA-2fjaB:
undetectable
4ctvB-2fjaB:
undetectable		 4ctvA-2fjaB:
18.25
4ctvB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.28A 4ctwA-2fjaA:
0.6
4ctwB-2fjaA:
undetectable		 4ctwA-2fjaA:
22.29
4ctwB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4ctwA-2fjaA:
0.6
4ctwB-2fjaA:
undetectable		 4ctwA-2fjaA:
22.29
4ctwB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 4ctwA-2fjaA:
0.6
4ctwB-2fjaA:
undetectable		 4ctwA-2fjaA:
22.29
4ctwB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 4ctwA-2fjaB:
undetectable
4ctwB-2fjaB:
undetectable		 4ctwA-2fjaB:
18.25
4ctwB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.30A 4ctxA-2fjaA:
0.7
4ctxB-2fjaA:
undetectable		 4ctxA-2fjaA:
22.29
4ctxB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.41A 4ctxA-2fjaA:
0.7
4ctxB-2fjaA:
undetectable		 4ctxA-2fjaA:
22.29
4ctxB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 4ctxA-2fjaA:
0.7
4ctxB-2fjaA:
undetectable		 4ctxA-2fjaA:
22.29
4ctxB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 4ctxA-2fjaB:
undetectable
4ctxB-2fjaB:
undetectable		 4ctxA-2fjaB:
18.25
4ctxB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.26A 4cx5A-2fjaA:
undetectable
4cx5B-2fjaA:
undetectable		 4cx5A-2fjaA:
22.44
4cx5B-2fjaA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.40A 4cx5A-2fjaA:
undetectable
4cx5B-2fjaA:
undetectable		 4cx5A-2fjaA:
22.44
4cx5B-2fjaA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 4cx5A-2fjaA:
undetectable
4cx5B-2fjaA:
undetectable		 4cx5A-2fjaA:
22.44
4cx5B-2fjaA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 4cx5A-2fjaB:
undetectable
4cx5B-2fjaB:
undetectable		 4cx5A-2fjaB:
18.25
4cx5B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.28A 4cx6A-2fjaA:
undetectable
4cx6B-2fjaA:
undetectable		 4cx6A-2fjaA:
22.44
4cx6B-2fjaA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4cx6A-2fjaA:
undetectable
4cx6B-2fjaA:
undetectable		 4cx6A-2fjaA:
22.44
4cx6B-2fjaA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 4cx6A-2fjaB:
undetectable
4cx6B-2fjaB:
undetectable		 4cx6A-2fjaB:
18.25
4cx6B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.40A 4d1nA-2fjaA:
undetectable
4d1nB-2fjaA:
undetectable		 4d1nA-2fjaA:
21.93
4d1nB-2fjaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.39A 4d1nA-2fjaB:
undetectable
4d1nB-2fjaB:
undetectable		 4d1nA-2fjaB:
18.57
4d1nB-2fjaB:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 4d1nC-2fjaA:
undetectable
4d1nD-2fjaA:
undetectable		 4d1nC-2fjaA:
21.93
4d1nD-2fjaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.30A 4d1nC-2fjaA:
undetectable
4d1nD-2fjaA:
undetectable		 4d1nC-2fjaA:
21.93
4d1nD-2fjaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 4d1nC-2fjaB:
undetectable
4d1nD-2fjaB:
undetectable		 4d1nC-2fjaB:
18.57
4d1nD-2fjaB:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.29A 4d2yA-2fjaA:
undetectable
4d2yB-2fjaA:
undetectable		 4d2yA-2fjaA:
22.29
4d2yB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 4d2yA-2fjaA:
undetectable
4d2yB-2fjaA:
undetectable		 4d2yA-2fjaA:
22.29
4d2yB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 4d2yA-2fjaB:
undetectable
4d2yB-2fjaB:
undetectable		 4d2yA-2fjaB:
18.25
4d2yB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.21A 4d2zA-2fjaA:
undetectable
4d2zB-2fjaA:
undetectable		 4d2zA-2fjaA:
22.29
4d2zB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.30A 4d2zA-2fjaA:
undetectable
4d2zB-2fjaA:
undetectable		 4d2zA-2fjaA:
22.29
4d2zB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.30A 4d2zA-2fjaA:
undetectable
4d2zB-2fjaA:
undetectable		 4d2zA-2fjaA:
22.29
4d2zB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 4d2zA-2fjaB:
undetectable
4d2zB-2fjaB:
undetectable		 4d2zA-2fjaB:
18.25
4d2zB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.34A 4d30A-2fjaA:
undetectable
4d30B-2fjaA:
undetectable		 4d30A-2fjaA:
22.29
4d30B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 4d30A-2fjaB:
undetectable
4d30B-2fjaB:
undetectable		 4d30A-2fjaB:
18.25
4d30B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.30A 4d31A-2fjaA:
undetectable
4d31B-2fjaA:
undetectable		 4d31A-2fjaA:
22.29
4d31B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.33A 4d31A-2fjaA:
undetectable
4d31B-2fjaA:
undetectable		 4d31A-2fjaA:
22.29
4d31B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.34A 4d31A-2fjaA:
undetectable
4d31B-2fjaA:
undetectable		 4d31A-2fjaA:
22.29
4d31B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 4d32A-2fjaA:
undetectable
4d32B-2fjaA:
undetectable		 4d32A-2fjaA:
22.29
4d32B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 4d32A-2fjaA:
undetectable
4d32B-2fjaA:
undetectable		 4d32A-2fjaA:
22.29
4d32B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 4d3bA-2fjaA:
1.5
4d3bB-2fjaA:
undetectable		 4d3bA-2fjaA:
22.29
4d3bB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 4d3bA-2fjaB:
undetectable
4d3bB-2fjaB:
undetectable		 4d3bA-2fjaB:
18.25
4d3bB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.33A 4d7oA-2fjaA:
undetectable
4d7oB-2fjaA:
1.5		 4d7oA-2fjaA:
22.29
4d7oB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4d7oA-2fjaA:
undetectable
4d7oB-2fjaA:
1.5		 4d7oA-2fjaA:
22.29
4d7oB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.33A 4d7oA-2fjaA:
undetectable
4d7oB-2fjaA:
1.5		 4d7oA-2fjaA:
22.29
4d7oB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.31A 4euxA-2fjaA:
undetectable
4euxB-2fjaA:
1.5		 4euxA-2fjaA:
22.29
4euxB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.40A 4euxA-2fjaA:
undetectable
4euxB-2fjaA:
1.5		 4euxA-2fjaA:
22.29
4euxB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.34A 4euxA-2fjaA:
undetectable
4euxB-2fjaA:
1.5		 4euxA-2fjaA:
22.29
4euxB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 LEU A 212
ALA A 192
VAL A  55
THR A 214
 None
None
None
FAD  A1000 (-4.2A)
 0.87A 4eyrA-2fjaA:
undetectable		 4eyrA-2fjaA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 8 MET B 756
PRO B 779
MET B 787
TRP B 788
 None
 1.08A 4f4dB-2fjaB:
undetectable		 4f4dB-2fjaB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 4fvwA-2fjaA:
undetectable
4fvwB-2fjaA:
undetectable		 4fvwA-2fjaA:
22.29
4fvwB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 4fvwA-2fjaB:
undetectable
4fvwB-2fjaB:
undetectable		 4fvwA-2fjaB:
18.25
4fvwB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4fvxA-2fjaA:
undetectable
4fvxB-2fjaA:
undetectable		 4fvxA-2fjaA:
22.29
4fvxB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 4fvxA-2fjaB:
undetectable
4fvxB-2fjaB:
undetectable		 4fvxA-2fjaB:
18.25
4fvxB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 4fvyA-2fjaA:
undetectable
4fvyB-2fjaA:
undetectable		 4fvyA-2fjaA:
22.29
4fvyB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 4fvzA-2fjaB:
undetectable
4fvzB-2fjaB:
undetectable		 4fvzA-2fjaB:
18.25
4fvzB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.31A 4fw0A-2fjaA:
undetectable
4fw0B-2fjaA:
undetectable		 4fw0A-2fjaA:
22.29
4fw0B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 4fw0A-2fjaA:
undetectable
4fw0B-2fjaA:
undetectable		 4fw0A-2fjaA:
22.29
4fw0B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 4fw0A-2fjaB:
undetectable
4fw0B-2fjaB:
undetectable		 4fw0A-2fjaB:
18.25
4fw0B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4gqeA-2fjaA:
undetectable
4gqeB-2fjaA:
undetectable		 4gqeA-2fjaA:
22.29
4gqeB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 4gqeA-2fjaB:
undetectable
4gqeB-2fjaB:
undetectable		 4gqeA-2fjaB:
18.25
4gqeB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 180
GLU A 483
VAL A 481
TRP A 572
HIS A 576
 None
 1.25A 4hvcB-2fjaA:
3.2		 4hvcB-2fjaA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 340
ALA A 284
PHE A 266
LEU A 363
PHE A 362
 None
 1.37A 4iaqA-2fjaA:
2.5		 4iaqA-2fjaA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 340
ALA A 284
PHE A 266
LEU A 363
PHE A 362
 None
 1.42A 4iarA-2fjaA:
undetectable		 4iarA-2fjaA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.27A 4imtA-2fjaA:
0.5
4imtB-2fjaA:
undetectable		 4imtA-2fjaA:
22.29
4imtB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.27A 4imwA-2fjaA:
undetectable
4imwB-2fjaA:
1.5		 4imwA-2fjaA:
22.29
4imwB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.15A 4jsfA-2fjaA:
0.5
4jsfB-2fjaA:
undetectable		 4jsfA-2fjaA:
22.29
4jsfB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4jsfA-2fjaA:
0.5
4jsfB-2fjaA:
undetectable		 4jsfA-2fjaA:
22.29
4jsfB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.26A 4jsfA-2fjaA:
0.5
4jsfB-2fjaA:
undetectable		 4jsfA-2fjaA:
22.29
4jsfB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.28A 4jsgA-2fjaA:
undetectable
4jsgB-2fjaA:
undetectable		 4jsgA-2fjaA:
22.29
4jsgB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 4jsgA-2fjaA:
undetectable
4jsgB-2fjaA:
undetectable		 4jsgA-2fjaA:
22.29
4jsgB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.30A 4jsgA-2fjaA:
undetectable
4jsgB-2fjaA:
undetectable		 4jsgA-2fjaA:
22.29
4jsgB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 4jsgA-2fjaB:
undetectable
4jsgB-2fjaB:
undetectable		 4jsgA-2fjaB:
18.25
4jsgB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.28A 4jshA-2fjaA:
undetectable
4jshB-2fjaA:
undetectable		 4jshA-2fjaA:
22.29
4jshB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 4jshA-2fjaB:
undetectable
4jshB-2fjaB:
undetectable		 4jshA-2fjaB:
18.25
4jshB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.21A 4jsiA-2fjaA:
undetectable
4jsiB-2fjaA:
undetectable		 4jsiA-2fjaA:
22.29
4jsiB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 4jsiA-2fjaA:
undetectable
4jsiB-2fjaA:
undetectable		 4jsiA-2fjaA:
22.29
4jsiB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 4jsiA-2fjaA:
undetectable
4jsiB-2fjaA:
undetectable		 4jsiA-2fjaA:
22.29
4jsiB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 4jsiA-2fjaB:
undetectable
4jsiB-2fjaB:
undetectable		 4jsiA-2fjaB:
18.25
4jsiB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 4jsjA-2fjaA:
undetectable
4jsjB-2fjaA:
undetectable		 4jsjA-2fjaA:
22.29
4jsjB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 4jsjA-2fjaB:
undetectable
4jsjB-2fjaB:
undetectable		 4jsjA-2fjaB:
18.25
4jsjB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4k5dA-2fjaA:
0.5
4k5dB-2fjaA:
undetectable		 4k5dA-2fjaA:
22.29
4k5dB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 4k5dA-2fjaB:
undetectable
4k5dB-2fjaB:
undetectable		 4k5dA-2fjaB:
18.25
4k5dB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 4k5eA-2fjaA:
undetectable
4k5eB-2fjaA:
0.6		 4k5eA-2fjaA:
22.29
4k5eB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 4k5eA-2fjaB:
undetectable
4k5eB-2fjaB:
undetectable		 4k5eA-2fjaB:
18.25
4k5eB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 4k5fA-2fjaA:
undetectable
4k5fB-2fjaA:
undetectable		 4k5fA-2fjaA:
22.29
4k5fB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 4k5fA-2fjaB:
undetectable
4k5fB-2fjaB:
undetectable		 4k5fA-2fjaB:
18.25
4k5fB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 4k5gA-2fjaA:
0.5
4k5gB-2fjaA:
undetectable		 4k5gA-2fjaA:
22.29
4k5gB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 4k5gA-2fjaB:
undetectable
4k5gB-2fjaB:
undetectable		 4k5gA-2fjaB:
18.25
4k5gB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.30A 4kchA-2fjaA:
undetectable
4kchB-2fjaA:
undetectable		 4kchA-2fjaA:
22.29
4kchB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 4kchA-2fjaA:
undetectable
4kchB-2fjaA:
undetectable		 4kchA-2fjaA:
22.29
4kchB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.34A 4kchA-2fjaA:
undetectable
4kchB-2fjaA:
undetectable		 4kchA-2fjaA:
22.29
4kchB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.25A 4kciA-2fjaA:
undetectable
4kciB-2fjaA:
undetectable		 4kciA-2fjaA:
22.29
4kciB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4kciA-2fjaA:
undetectable
4kciB-2fjaA:
undetectable		 4kciA-2fjaA:
22.29
4kciB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 4kciA-2fjaB:
undetectable
4kciB-2fjaB:
undetectable		 4kciA-2fjaB:
18.25
4kciB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 4kcjA-2fjaA:
undetectable
4kcjB-2fjaA:
undetectable		 4kcjA-2fjaA:
22.29
4kcjB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 4kcjA-2fjaB:
undetectable
4kcjB-2fjaB:
undetectable		 4kcjA-2fjaB:
18.25
4kcjB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.24A 4kckA-2fjaA:
0.6
4kckB-2fjaA:
undetectable		 4kckA-2fjaA:
22.29
4kckB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.31A 4kckA-2fjaA:
0.6
4kckB-2fjaA:
undetectable		 4kckA-2fjaA:
22.29
4kckB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 4kckA-2fjaA:
0.6
4kckB-2fjaA:
undetectable		 4kckA-2fjaA:
22.29
4kckB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 4kckA-2fjaB:
undetectable
4kckB-2fjaB:
undetectable		 4kckA-2fjaB:
18.25
4kckB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.29A 4kclA-2fjaA:
undetectable
4kclB-2fjaA:
1.5		 4kclA-2fjaA:
22.29
4kclB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 4kclA-2fjaA:
undetectable
4kclB-2fjaA:
1.5		 4kclA-2fjaA:
22.29
4kclB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.31A 4kclA-2fjaA:
undetectable
4kclB-2fjaA:
1.5		 4kclA-2fjaA:
22.29
4kclB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 4kclA-2fjaB:
undetectable
4kclB-2fjaB:
undetectable		 4kclA-2fjaB:
18.25
4kclB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.29A 4kcmA-2fjaA:
undetectable
4kcmB-2fjaA:
undetectable		 4kcmA-2fjaA:
22.29
4kcmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.33A 4kcmA-2fjaA:
undetectable
4kcmB-2fjaA:
undetectable		 4kcmA-2fjaA:
22.29
4kcmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.35A 4kcmA-2fjaA:
undetectable
4kcmB-2fjaA:
undetectable		 4kcmA-2fjaA:
22.29
4kcmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.24A 4kcnA-2fjaA:
undetectable
4kcnB-2fjaA:
0.6		 4kcnA-2fjaA:
22.29
4kcnB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 4kcnA-2fjaA:
undetectable
4kcnB-2fjaA:
0.6		 4kcnA-2fjaA:
22.29
4kcnB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.27A 4kcnA-2fjaA:
undetectable
4kcnB-2fjaA:
0.6		 4kcnA-2fjaA:
22.29
4kcnB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 4kcnA-2fjaB:
undetectable
4kcnB-2fjaB:
undetectable		 4kcnA-2fjaB:
18.25
4kcnB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.29A 4kcoA-2fjaA:
undetectable
4kcoB-2fjaA:
undetectable		 4kcoA-2fjaA:
22.29
4kcoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 4kcoA-2fjaA:
undetectable
4kcoB-2fjaA:
undetectable		 4kcoA-2fjaA:
22.29
4kcoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.27A 4kcoA-2fjaA:
undetectable
4kcoB-2fjaA:
undetectable		 4kcoA-2fjaA:
22.29
4kcoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 4kcoA-2fjaB:
undetectable
4kcoB-2fjaB:
undetectable		 4kcoA-2fjaB:
18.25
4kcoB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 MET B 756
PRO B 779
MET B 787
TRP B 788
 None
 1.11A 4kmmA-2fjaB:
undetectable		 4kmmA-2fjaB:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_A_LYAA304_1
(FOLATE RECEPTOR BETA)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 ASP A  99
TRP A 234
HIS A 398
GLY A 216
TYR A  95
 None
FAD  A1000 ( 4.4A)
None
None
None
 1.49A 4kn2A-2fjaA:
0.0		 4kn2A-2fjaA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_B_LYAB304_1
(FOLATE RECEPTOR BETA)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 ASP A  99
TRP A 234
HIS A 398
GLY A 216
TYR A  95
 None
FAD  A1000 ( 4.4A)
None
None
None
 1.50A 4kn2B-2fjaA:
0.0		 4kn2B-2fjaA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_1
(FOLATE RECEPTOR BETA)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 ASP A  99
TRP A 234
HIS A 398
GLY A 216
TYR A  95
 None
FAD  A1000 ( 4.4A)
None
None
None
 1.48A 4kn2C-2fjaA:
0.0		 4kn2C-2fjaA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 4luxA-2fjaA:
0.6
4luxB-2fjaA:
undetectable		 4luxA-2fjaA:
22.29
4luxB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 4luxA-2fjaB:
undetectable
4luxB-2fjaB:
undetectable		 4luxA-2fjaB:
18.25
4luxB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 TYR A 489
THR A  53
LEU A  26
THR A  23
 None
 1.11A 4mbsA-2fjaA:
undetectable		 4mbsA-2fjaA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 SER A 397
ILE A  73
ASN A  74
SER A  33
PHE A 123
 FAD  A1000 (-2.7A)
None
FAD  A1000 ( 3.2A)
FAD  A1000 (-2.6A)
None
 1.17A 4obwC-2fjaA:
undetectable		 4obwC-2fjaA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q36_A_GCSA404_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN TCP24)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 5 MET A 147
TRP A 131
HIS A 353
PHE A 280
 None
 1.45A 4q36A-2fjaA:
0.0		 4q36A-2fjaA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 5 ILE A 312
PRO A 313
HIS A 259
TYR A 601
 None
 1.30A 4s0vA-2fjaA:
3.3		 4s0vA-2fjaA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 4uchA-2fjaA:
0.5
4uchB-2fjaA:
undetectable		 4uchA-2fjaA:
21.43
4uchB-2fjaA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 4ugzA-2fjaA:
undetectable
4ugzB-2fjaA:
undetectable		 4ugzA-2fjaA:
22.29
4ugzB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 4ugzA-2fjaB:
undetectable
4ugzB-2fjaB:
undetectable		 4ugzA-2fjaB:
18.25
4ugzB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 4uh0A-2fjaA:
0.5
4uh0B-2fjaA:
0.4		 4uh0A-2fjaA:
22.29
4uh0B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 4uh0A-2fjaB:
undetectable
4uh0B-2fjaB:
undetectable		 4uh0A-2fjaB:
18.25
4uh0B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 4uh1A-2fjaA:
undetectable
4uh1B-2fjaA:
undetectable		 4uh1A-2fjaA:
22.29
4uh1B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 4uh1A-2fjaB:
undetectable
4uh1B-2fjaB:
undetectable		 4uh1A-2fjaB:
18.25
4uh1B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4uh2A-2fjaA:
undetectable
4uh2B-2fjaA:
undetectable		 4uh2A-2fjaA:
22.29
4uh2B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 4uh2A-2fjaB:
undetectable
4uh2B-2fjaB:
undetectable		 4uh2A-2fjaB:
18.25
4uh2B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 4uh3A-2fjaA:
0.6
4uh3B-2fjaA:
undetectable		 4uh3A-2fjaA:
22.29
4uh3B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4uh4A-2fjaA:
undetectable
4uh4B-2fjaA:
undetectable		 4uh4A-2fjaA:
22.29
4uh4B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 4uh4A-2fjaB:
undetectable
4uh4B-2fjaB:
undetectable		 4uh4A-2fjaB:
18.25
4uh4B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.34A 4uh5A-2fjaA:
undetectable
4uh5B-2fjaA:
undetectable		 4uh5A-2fjaA:
22.42
4uh5B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4uh5A-2fjaA:
undetectable
4uh5B-2fjaA:
undetectable		 4uh5A-2fjaA:
22.42
4uh5B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 4uh5A-2fjaB:
undetectable
4uh5B-2fjaB:
undetectable		 4uh5A-2fjaB:
19.00
4uh5B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.40A 4uh6A-2fjaA:
0.5
4uh6B-2fjaA:
undetectable		 4uh6A-2fjaA:
22.42
4uh6B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 4uh6A-2fjaB:
undetectable
4uh6B-2fjaB:
undetectable		 4uh6A-2fjaB:
19.00
4uh6B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.28A 4upmA-2fjaA:
undetectable
4upmB-2fjaA:
undetectable		 4upmA-2fjaA:
22.29
4upmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 4upmA-2fjaA:
undetectable
4upmB-2fjaA:
undetectable		 4upmA-2fjaA:
22.29
4upmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 4upmA-2fjaA:
undetectable
4upmB-2fjaA:
undetectable		 4upmA-2fjaA:
22.29
4upmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 4upmA-2fjaB:
undetectable
4upmB-2fjaB:
undetectable		 4upmA-2fjaB:
18.25
4upmB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.29A 4upnA-2fjaA:
undetectable
4upnB-2fjaA:
undetectable		 4upnA-2fjaA:
22.29
4upnB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 4upnA-2fjaA:
undetectable
4upnB-2fjaA:
undetectable		 4upnA-2fjaA:
22.29
4upnB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 4upnA-2fjaA:
undetectable
4upnB-2fjaA:
1.5		 4upnA-2fjaA:
22.29
4upnB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 4upnA-2fjaB:
undetectable
4upnB-2fjaB:
undetectable		 4upnA-2fjaB:
18.25
4upnB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 4upoA-2fjaA:
undetectable
4upoB-2fjaA:
undetectable		 4upoA-2fjaA:
22.29
4upoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 4upoA-2fjaA:
undetectable
4upoB-2fjaA:
undetectable		 4upoA-2fjaA:
22.29
4upoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 4upoA-2fjaB:
undetectable
4upoB-2fjaB:
undetectable		 4upoA-2fjaB:
18.25
4upoB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 4uppA-2fjaA:
undetectable
4uppB-2fjaA:
undetectable		 4uppA-2fjaA:
22.29
4uppB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 4uppA-2fjaB:
undetectable
4uppB-2fjaB:
undetectable		 4uppA-2fjaB:
18.25
4uppB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.32A 4v3uA-2fjaA:
undetectable
4v3uB-2fjaA:
undetectable		 4v3uA-2fjaA:
21.93
4v3uB-2fjaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.31A 4v3uA-2fjaA:
undetectable
4v3uB-2fjaA:
undetectable		 4v3uA-2fjaA:
21.93
4v3uB-2fjaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 4v3uA-2fjaA:
0.0
4v3uB-2fjaA:
undetectable		 4v3uA-2fjaA:
21.93
4v3uB-2fjaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 4v3uA-2fjaB:
undetectable
4v3uB-2fjaB:
undetectable		 4v3uA-2fjaB:
18.57
4v3uB-2fjaB:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.31A 4v3uC-2fjaA:
undetectable
4v3uD-2fjaA:
undetectable		 4v3uC-2fjaA:
21.93
4v3uD-2fjaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 4v3uC-2fjaA:
undetectable
4v3uD-2fjaA:
undetectable		 4v3uC-2fjaA:
21.93
4v3uD-2fjaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.27A 4v3vA-2fjaA:
0.7
4v3vB-2fjaA:
undetectable		 4v3vA-2fjaA:
22.29
4v3vB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.32A 4v3vA-2fjaA:
0.7
4v3vB-2fjaA:
undetectable		 4v3vA-2fjaA:
22.29
4v3vB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 4v3vA-2fjaA:
0.7
4v3vB-2fjaA:
undetectable		 4v3vA-2fjaA:
22.29
4v3vB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 4v3vA-2fjaB:
undetectable
4v3vB-2fjaB:
undetectable		 4v3vA-2fjaB:
18.25
4v3vB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.17A 4v3wA-2fjaA:
undetectable
4v3wB-2fjaA:
undetectable		 4v3wA-2fjaA:
22.29
4v3wB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.36A 4v3xA-2fjaA:
undetectable
4v3xB-2fjaA:
undetectable		 4v3xA-2fjaA:
22.29
4v3xB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.27A 4v3yA-2fjaA:
undetectable
4v3yB-2fjaA:
undetectable		 4v3yA-2fjaA:
22.29
4v3yB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 4v3yA-2fjaA:
undetectable
4v3yB-2fjaA:
undetectable		 4v3yA-2fjaA:
22.29
4v3yB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.30A 4v3yA-2fjaA:
undetectable
4v3yB-2fjaA:
undetectable		 4v3yA-2fjaA:
22.29
4v3yB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.34A 4v3zA-2fjaA:
undetectable
4v3zB-2fjaA:
undetectable		 4v3zA-2fjaA:
22.29
4v3zB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.33A 4v3zA-2fjaA:
undetectable
4v3zB-2fjaA:
undetectable		 4v3zA-2fjaA:
22.29
4v3zB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 10 PHE A 257
GLY A 438
LEU A 108
ALA A 443
ALA A 402
 None
FAD  A1000 (-3.5A)
None
None
None
 1.29A 4wnuD-2fjaA:
undetectable		 4wnuD-2fjaA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		4 / 5 GLY A 118
TYR A 112
GLU B 834
ASP A 117
 None
 1.20A 4xueA-2fjaA:
undetectable		 4xueA-2fjaA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 GLY A 216
ASP A 239
GLY A 243
ARG A 577
 None
FAD  A1000 (-2.9A)
None
None
 0.96A 4z53A-2fjaA:
undetectable
4z53B-2fjaA:
undetectable		 4z53A-2fjaA:
23.35
4z53B-2fjaA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 9 PHE A 257
GLY A 241
THR A 214
LEU A 212
LEU A 434
 None
None
FAD  A1000 (-4.2A)
None
None
 1.36A 4ze0A-2fjaA:
undetectable		 4ze0A-2fjaA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ILE A  27
GLU A  56
GLY A  31
GLY A  34
 None
FAD  A1000 (-2.7A)
FAD  A1000 (-3.2A)
None
 0.85A 5a06C-2fjaA:
2.6		 5a06C-2fjaA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.12A 5ad4A-2fjaA:
undetectable
5ad4B-2fjaA:
undetectable		 5ad4A-2fjaA:
22.29
5ad4B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5ad4A-2fjaA:
undetectable
5ad4B-2fjaA:
undetectable		 5ad4A-2fjaA:
22.29
5ad4B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.23A 5ad4A-2fjaA:
undetectable
5ad4B-2fjaA:
undetectable		 5ad4A-2fjaA:
22.29
5ad4B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 5ad4A-2fjaB:
undetectable
5ad4B-2fjaB:
undetectable		 5ad4A-2fjaB:
18.25
5ad4B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5ad5A-2fjaA:
undetectable
5ad5B-2fjaA:
undetectable		 5ad5A-2fjaA:
22.29
5ad5B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 5ad5A-2fjaB:
undetectable
5ad5B-2fjaB:
undetectable		 5ad5A-2fjaB:
18.25
5ad5B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.20A 5ad6A-2fjaA:
0.5
5ad6B-2fjaA:
undetectable		 5ad6A-2fjaA:
22.29
5ad6B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.33A 5ad6A-2fjaA:
0.5
5ad6B-2fjaA:
undetectable		 5ad6A-2fjaA:
22.29
5ad6B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 5ad6A-2fjaB:
undetectable
5ad6B-2fjaB:
undetectable		 5ad6A-2fjaB:
18.25
5ad6B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 5ad7A-2fjaB:
undetectable
5ad7B-2fjaB:
undetectable		 5ad7A-2fjaB:
18.25
5ad7B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 5ad8A-2fjaB:
undetectable
5ad8B-2fjaB:
undetectable		 5ad8A-2fjaB:
18.25
5ad8B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 5ad9A-2fjaA:
undetectable
5ad9B-2fjaA:
undetectable		 5ad9A-2fjaA:
22.29
5ad9B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.29A 5ad9A-2fjaB:
undetectable
5ad9B-2fjaB:
undetectable		 5ad9A-2fjaB:
18.25
5ad9B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5adaA-2fjaA:
undetectable
5adaB-2fjaA:
undetectable		 5adaA-2fjaA:
22.29
5adaB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.31A 5adaA-2fjaB:
undetectable
5adaB-2fjaB:
undetectable		 5adaA-2fjaB:
18.25
5adaB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 5adbA-2fjaB:
undetectable
5adbB-2fjaB:
undetectable		 5adbA-2fjaB:
18.25
5adbB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5adcA-2fjaA:
undetectable
5adcB-2fjaA:
undetectable		 5adcA-2fjaA:
22.29
5adcB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 5adcA-2fjaB:
undetectable
5adcB-2fjaB:
undetectable		 5adcA-2fjaB:
18.25
5adcB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.27A 5adeA-2fjaB:
undetectable
5adeB-2fjaB:
undetectable		 5adeA-2fjaB:
18.25
5adeB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5adfA-2fjaA:
undetectable
5adfB-2fjaA:
1.5		 5adfA-2fjaA:
22.42
5adfB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 5adgA-2fjaA:
undetectable
5adgB-2fjaA:
undetectable		 5adgA-2fjaA:
22.42
5adgB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 5adgA-2fjaB:
undetectable
5adgB-2fjaB:
undetectable		 5adgA-2fjaB:
19.00
5adgB-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.33A 5adiA-2fjaA:
undetectable
5adiB-2fjaA:
1.5		 5adiA-2fjaA:
22.42
5adiB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 5agkA-2fjaA:
undetectable
5agkB-2fjaA:
undetectable		 5agkA-2fjaA:
22.29
5agkB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 5agkA-2fjaB:
undetectable
5agkB-2fjaB:
undetectable		 5agkA-2fjaB:
18.25
5agkB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 5aglA-2fjaA:
undetectable
5aglB-2fjaA:
undetectable		 5aglA-2fjaA:
22.29
5aglB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 5aglA-2fjaB:
undetectable
5aglB-2fjaB:
undetectable		 5aglA-2fjaB:
18.25
5aglB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 5agmA-2fjaA:
undetectable
5agmB-2fjaA:
undetectable		 5agmA-2fjaA:
22.29
5agmB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5agnA-2fjaA:
undetectable
5agnB-2fjaA:
undetectable		 5agnA-2fjaA:
22.29
5agnB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 5agnA-2fjaB:
undetectable
5agnB-2fjaB:
undetectable		 5agnA-2fjaB:
18.25
5agnB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.29A 5agoA-2fjaA:
undetectable
5agoB-2fjaA:
undetectable		 5agoA-2fjaA:
22.29
5agoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 5agoA-2fjaA:
undetectable
5agoB-2fjaA:
undetectable		 5agoA-2fjaA:
22.29
5agoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 5agoA-2fjaB:
undetectable
5agoB-2fjaB:
undetectable		 5agoA-2fjaB:
18.25
5agoB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 GLY A 456
GLY A 118
HIS A 115
ALA B 832
ILE B 837
 None
 1.11A 5eevA-2fjaA:
undetectable
5eevB-2fjaA:
undetectable		 5eevA-2fjaA:
7.47
5eevB-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 GLY A 456
GLY A 118
HIS A 115
ALA B 832
ILE B 837
 None
 1.11A 5eewA-2fjaA:
undetectable
5eewB-2fjaA:
undetectable		 5eewA-2fjaA:
7.47
5eewB-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 GLY A 456
GLY A 118
HIS A 115
ALA B 832
ILE B 837
 None
 1.11A 5eexA-2fjaA:
undetectable
5eexB-2fjaA:
undetectable		 5eexA-2fjaA:
7.47
5eexB-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 GLY A 456
GLY A 118
HIS A 115
ALA B 832
ILE B 837
 None
 1.11A 5eeyA-2fjaA:
undetectable
5eeyB-2fjaA:
undetectable		 5eeyA-2fjaA:
7.47
5eeyB-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 GLY A 456
GLY A 118
HIS A 115
ALA B 832
ILE B 837
 None
 1.11A 5eezA-2fjaA:
undetectable
5eezB-2fjaA:
undetectable		 5eezA-2fjaA:
7.47
5eezB-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 GLY A 456
GLY A 118
HIS A 115
ALA B 832
ILE B 837
 None
 1.10A 5ef0A-2fjaA:
undetectable
5ef0B-2fjaA:
undetectable		 5ef0A-2fjaA:
7.47
5ef0B-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 GLY A 456
GLY A 118
HIS A 115
ALA B 832
ILE B 837
 None
 1.10A 5ef1A-2fjaA:
undetectable
5ef1B-2fjaA:
undetectable		 5ef1A-2fjaA:
7.47
5ef1B-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 GLY A 456
GLY A 118
HIS A 115
ALA B 832
ILE B 837
 None
 1.11A 5ef2A-2fjaA:
undetectable
5ef2B-2fjaA:
undetectable		 5ef2A-2fjaA:
7.47
5ef2B-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 GLY A 456
GLY A 118
HIS A 115
ALA B 832
ILE B 837
 None
 1.10A 5ef3A-2fjaA:
undetectable
5ef3B-2fjaA:
undetectable		 5ef3A-2fjaA:
7.47
5ef3B-2fjaA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		3 / 3 ARG A 586
VAL A 578
TRP A 579
 None
 1.00A 5fvoA-2fjaA:
undetectable		 5fvoA-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.20A 5fvpA-2fjaA:
undetectable
5fvpB-2fjaA:
undetectable		 5fvpA-2fjaA:
22.29
5fvpB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.32A 5fvpA-2fjaA:
undetectable
5fvpB-2fjaA:
undetectable		 5fvpA-2fjaA:
22.29
5fvpB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 5fvpA-2fjaB:
undetectable
5fvpB-2fjaB:
undetectable		 5fvpA-2fjaB:
18.25
5fvpB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 5fvqA-2fjaB:
undetectable
5fvqB-2fjaB:
undetectable		 5fvqA-2fjaB:
18.25
5fvqB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.31A 5fvrA-2fjaA:
undetectable
5fvrB-2fjaA:
undetectable		 5fvrA-2fjaA:
22.29
5fvrB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.41A 5fvrA-2fjaA:
undetectable
5fvrB-2fjaA:
undetectable		 5fvrA-2fjaA:
22.29
5fvrB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.29A 5fvrA-2fjaA:
undetectable
5fvrB-2fjaA:
undetectable		 5fvrA-2fjaA:
22.29
5fvrB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 5fvrA-2fjaB:
undetectable
5fvrB-2fjaB:
undetectable		 5fvrA-2fjaB:
18.25
5fvrB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 5fvsA-2fjaB:
undetectable
5fvsB-2fjaB:
undetectable		 5fvsA-2fjaB:
18.25
5fvsB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.32A 5fvtA-2fjaA:
undetectable
5fvtB-2fjaA:
undetectable		 5fvtA-2fjaA:
22.29
5fvtB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.33A 5fvtA-2fjaA:
undetectable
5fvtB-2fjaA:
undetectable		 5fvtA-2fjaA:
22.29
5fvtB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 5fvtA-2fjaB:
undetectable
5fvtB-2fjaB:
undetectable		 5fvtA-2fjaB:
18.25
5fvtB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 5fvuA-2fjaB:
undetectable
5fvuB-2fjaB:
undetectable		 5fvuA-2fjaB:
19.00
5fvuB-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.31A 5fvvA-2fjaA:
undetectable
5fvvB-2fjaA:
undetectable		 5fvvA-2fjaA:
22.42
5fvvB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.41A 5fvvA-2fjaA:
undetectable
5fvvB-2fjaA:
undetectable		 5fvvA-2fjaA:
22.42
5fvvB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.33A 5fvvA-2fjaA:
undetectable
5fvvB-2fjaA:
undetectable		 5fvvA-2fjaA:
22.42
5fvvB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.30A 5fvwA-2fjaA:
undetectable
5fvwB-2fjaA:
undetectable		 5fvwA-2fjaA:
22.42
5fvwB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 5fvwA-2fjaA:
undetectable
5fvwB-2fjaA:
undetectable		 5fvwA-2fjaA:
22.42
5fvwB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 5fvwA-2fjaB:
undetectable
5fvwB-2fjaB:
undetectable		 5fvwA-2fjaB:
19.00
5fvwB-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 5fvxA-2fjaA:
undetectable
5fvxB-2fjaA:
undetectable		 5fvxA-2fjaA:
22.42
5fvxB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 5fw0A-2fjaA:
undetectable
5fw0B-2fjaA:
undetectable		 5fw0A-2fjaA:
22.29
5fw0B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.26A 5fw0A-2fjaA:
undetectable
5fw0B-2fjaA:
undetectable		 5fw0A-2fjaA:
22.29
5fw0B-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 5fw0A-2fjaB:
undetectable
5fw0B-2fjaB:
undetectable		 5fw0A-2fjaB:
18.25
5fw0B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.31A 5g0nA-2fjaA:
undetectable
5g0nB-2fjaA:
undetectable		 5g0nA-2fjaA:
22.29
5g0nB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 5g0nA-2fjaB:
undetectable
5g0nB-2fjaB:
undetectable		 5g0nA-2fjaB:
18.25
5g0nB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.24A 5g0oA-2fjaA:
undetectable
5g0oB-2fjaA:
undetectable		 5g0oA-2fjaA:
22.29
5g0oB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 5g0oA-2fjaA:
undetectable
5g0oB-2fjaA:
undetectable		 5g0oA-2fjaA:
22.29
5g0oB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 5g0oA-2fjaA:
undetectable
5g0oB-2fjaA:
undetectable		 5g0oA-2fjaA:
22.29
5g0oB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 5g0oA-2fjaB:
undetectable
5g0oB-2fjaB:
undetectable		 5g0oA-2fjaB:
18.25
5g0oB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		4 / 4 THR A 119
LEU B 831
HIS A 115
GLY B 833
 None
 1.29A 5gwyA-2fjaA:
undetectable		 5gwyA-2fjaA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLY A  29
GLU A  56
LYS A  57
ALA A  58
 FAD  A1000 (-3.3A)
FAD  A1000 (-2.7A)
FAD  A1000 (-4.0A)
FAD  A1000 ( 4.6A)
 0.65A 5mvsA-2fjaA:
undetectable		 5mvsA-2fjaA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLY A  30
GLU A  56
LYS A  57
ALA A  58
 FAD  A1000 (-4.3A)
FAD  A1000 (-2.7A)
FAD  A1000 (-4.0A)
FAD  A1000 ( 4.6A)
 0.99A 5mvsA-2fjaA:
undetectable		 5mvsA-2fjaA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 PHE A 435
LEU A 212
ARG A 427
GLY A 438
VAL A 406
 None
None
None
FAD  A1000 (-3.5A)
None
 1.27A 5o4yD-2fjaA:
undetectable
5o4yE-2fjaA:
undetectable		 5o4yD-2fjaA:
2.00
5o4yE-2fjaA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 9 LEU A 212
ILE A  28
GLY A  29
GLY A  34
LEU A 434
 None
None
FAD  A1000 (-3.3A)
None
None
 0.89A 5o96A-2fjaA:
2.2
5o96B-2fjaA:
2.4		 5o96A-2fjaA:
19.79
5o96B-2fjaA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  54
GLY A  36
ALA A  37
GLY A 438
ILE A  27
 None
None
None
FAD  A1000 (-3.5A)
None
 0.82A 5t8hB-2fjaA:
undetectable		 5t8hB-2fjaA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 212
ILE A  28
GLY A  29
GLY A  34
LEU A 434
 None
None
FAD  A1000 (-3.3A)
None
None
 0.90A 5twjA-2fjaA:
undetectable		 5twjA-2fjaA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 10 LEU A 212
ILE A  28
GLY A  29
GLY A  34
LEU A 434
 None
None
FAD  A1000 (-3.3A)
None
None
 0.95A 5twjB-2fjaA:
undetectable		 5twjB-2fjaA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 11 LEU A 212
ILE A  28
GLY A  29
GLY A  34
LEU A 434
 None
None
FAD  A1000 (-3.3A)
None
None
 0.93A 5twjD-2fjaA:
undetectable		 5twjD-2fjaA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		3 / 3 ARG A 317
PRO A 315
TYR A  95
 None
 1.03A 5tzoB-2fjaA:
undetectable		 5tzoB-2fjaA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 ILE A  25
ALA A 207
LEU A 434
ILE A  27
 None
 0.81A 5uihA-2fjaA:
undetectable		 5uihA-2fjaA:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 5unrA-2fjaB:
undetectable
5unrB-2fjaB:
undetectable		 5unrA-2fjaB:
18.25
5unrB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.40A 5unsA-2fjaA:
undetectable
5unsB-2fjaA:
undetectable		 5unsA-2fjaA:
22.29
5unsB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 5unsA-2fjaB:
undetectable
5unsB-2fjaB:
undetectable		 5unsA-2fjaB:
18.25
5unsB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 5untA-2fjaA:
undetectable
5untB-2fjaA:
undetectable		 5untA-2fjaA:
22.29
5untB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 5untA-2fjaB:
undetectable
5untB-2fjaB:
undetectable		 5untA-2fjaB:
18.25
5untB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5unuA-2fjaA:
undetectable
5unuB-2fjaA:
undetectable		 5unuA-2fjaA:
22.29
5unuB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 5unuA-2fjaB:
undetectable
5unuB-2fjaB:
undetectable		 5unuA-2fjaB:
18.25
5unuB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.10A 5unvA-2fjaA:
undetectable
5unvB-2fjaA:
undetectable		 5unvA-2fjaA:
22.29
5unvB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.42A 5unvA-2fjaA:
undetectable
5unvB-2fjaA:
undetectable		 5unvA-2fjaA:
22.29
5unvB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.16A 5unvA-2fjaA:
undetectable
5unvB-2fjaA:
undetectable		 5unvA-2fjaA:
22.29
5unvB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 5unvA-2fjaB:
undetectable
5unvB-2fjaB:
undetectable		 5unvA-2fjaB:
18.25
5unvB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 5unwA-2fjaA:
undetectable
5unwB-2fjaA:
undetectable		 5unwA-2fjaA:
22.29
5unwB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 5unwA-2fjaB:
undetectable
5unwB-2fjaB:
undetectable		 5unwA-2fjaB:
18.25
5unwB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.28A 5unxA-2fjaA:
undetectable
5unxB-2fjaA:
undetectable		 5unxA-2fjaA:
22.29
5unxB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.28A 5unxA-2fjaB:
undetectable
5unxB-2fjaB:
undetectable		 5unxA-2fjaB:
18.25
5unxB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.33A 5unyA-2fjaA:
undetectable
5unyB-2fjaA:
undetectable		 5unyA-2fjaA:
22.29
5unyB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 5unyA-2fjaB:
undetectable
5unyB-2fjaB:
undetectable		 5unyA-2fjaB:
18.25
5unyB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 5unzA-2fjaB:
undetectable
5unzB-2fjaB:
undetectable		 5unzA-2fjaB:
18.25
5unzB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 5uo0A-2fjaB:
undetectable
5uo0B-2fjaB:
undetectable		 5uo0A-2fjaB:
18.25
5uo0B-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 5uo1A-2fjaA:
0.5
5uo1B-2fjaA:
undetectable		 5uo1A-2fjaA:
22.42
5uo1B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 5uo1A-2fjaB:
undetectable
5uo1B-2fjaB:
undetectable		 5uo1A-2fjaB:
19.00
5uo1B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.30A 5uo2A-2fjaA:
0.5
5uo2B-2fjaA:
undetectable		 5uo2A-2fjaA:
22.42
5uo2B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 5uo2A-2fjaB:
undetectable
5uo2B-2fjaB:
undetectable		 5uo2A-2fjaB:
19.00
5uo2B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.31A 5uo3A-2fjaA:
undetectable
5uo3B-2fjaA:
undetectable		 5uo3A-2fjaA:
22.42
5uo3B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 5uo3A-2fjaB:
undetectable
5uo3B-2fjaB:
undetectable		 5uo3A-2fjaB:
19.00
5uo3B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 5uo4A-2fjaA:
undetectable
5uo4B-2fjaA:
undetectable		 5uo4A-2fjaA:
22.42
5uo4B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 5uo4A-2fjaB:
undetectable
5uo4B-2fjaB:
undetectable		 5uo4A-2fjaB:
19.00
5uo4B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 5uo5A-2fjaA:
undetectable
5uo5B-2fjaA:
undetectable		 5uo5A-2fjaA:
22.42
5uo5B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 5uo5A-2fjaB:
undetectable
5uo5B-2fjaB:
undetectable		 5uo5A-2fjaB:
19.00
5uo5B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 5uo6A-2fjaB:
undetectable
5uo6B-2fjaB:
undetectable		 5uo6A-2fjaB:
19.00
5uo6B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 5uo7A-2fjaB:
undetectable
5uo7B-2fjaB:
undetectable		 5uo7A-2fjaB:
19.00
5uo7B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 456
GLY A  29
GLY A  31
GLY A  36
PHE A 175
 None
FAD  A1000 (-3.3A)
FAD  A1000 (-3.2A)
None
FAD  A1000 (-3.5A)
 0.88A 5vimA-2fjaA:
undetectable		 5vimA-2fjaA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 456
GLY A  29
GLY A  31
GLY A  36
PHE A 175
 None
FAD  A1000 (-3.3A)
FAD  A1000 (-3.2A)
None
FAD  A1000 (-3.5A)
 0.89A 5vimB-2fjaA:
undetectable		 5vimB-2fjaA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 10 ILE A 293
ILE A 312
LEU A 316
ILE A 332
ASN A 329
 None
 1.31A 5vkqA-2fjaA:
undetectable
5vkqD-2fjaA:
undetectable		 5vkqA-2fjaA:
16.92
5vkqD-2fjaA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 10 ILE A 332
ASN A 329
ILE A 293
ILE A 312
LEU A 316
 None
 1.30A 5vkqA-2fjaA:
undetectable
5vkqB-2fjaA:
undetectable		 5vkqA-2fjaA:
16.92
5vkqB-2fjaA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 10 ILE A 332
ASN A 329
ILE A 293
ILE A 312
LEU A 316
 None
 1.32A 5vkqC-2fjaA:
undetectable
5vkqD-2fjaA:
undetectable		 5vkqC-2fjaA:
16.92
5vkqD-2fjaA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 5vuiA-2fjaA:
undetectable
5vuiB-2fjaA:
undetectable		 5vuiA-2fjaA:
22.29
5vuiB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 5vuiA-2fjaB:
undetectable
5vuiB-2fjaB:
undetectable		 5vuiA-2fjaB:
18.25
5vuiB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.05A 5vujA-2fjaA:
undetectable
5vujB-2fjaA:
undetectable		 5vujA-2fjaA:
22.29
5vujB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 5vujA-2fjaA:
undetectable
5vujB-2fjaA:
undetectable		 5vujA-2fjaA:
22.29
5vujB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.12A 5vujA-2fjaA:
undetectable
5vujB-2fjaA:
undetectable		 5vujA-2fjaA:
22.29
5vujB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 5vujA-2fjaB:
undetectable
5vujB-2fjaB:
undetectable		 5vujA-2fjaB:
18.25
5vujB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.16A 5vukA-2fjaA:
undetectable
5vukB-2fjaA:
undetectable		 5vukA-2fjaA:
22.29
5vukB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 5vukA-2fjaA:
undetectable
5vukB-2fjaA:
undetectable		 5vukA-2fjaA:
22.29
5vukB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 5vukA-2fjaB:
undetectable
5vukB-2fjaB:
undetectable		 5vukA-2fjaB:
18.25
5vukB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5vulA-2fjaA:
undetectable
5vulB-2fjaA:
undetectable		 5vulA-2fjaA:
22.29
5vulB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.24A 5vulA-2fjaA:
undetectable
5vulB-2fjaA:
undetectable		 5vulA-2fjaA:
22.29
5vulB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 5vulA-2fjaB:
undetectable
5vulB-2fjaB:
undetectable		 5vulA-2fjaB:
18.25
5vulB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.22A 5vumA-2fjaA:
undetectable
5vumB-2fjaA:
undetectable		 5vumA-2fjaA:
22.29
5vumB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5vumA-2fjaA:
undetectable
5vumB-2fjaA:
undetectable		 5vumA-2fjaA:
22.29
5vumB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.24A 5vumA-2fjaA:
0.5
5vumB-2fjaA:
undetectable		 5vumA-2fjaA:
22.29
5vumB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 5vumA-2fjaB:
undetectable
5vumB-2fjaB:
undetectable		 5vumA-2fjaB:
18.25
5vumB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.29A 5vunA-2fjaA:
undetectable
5vunB-2fjaA:
undetectable		 5vunA-2fjaA:
22.29
5vunB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5vunA-2fjaA:
undetectable
5vunB-2fjaA:
undetectable		 5vunA-2fjaA:
22.29
5vunB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 5vunA-2fjaA:
undetectable
5vunB-2fjaA:
undetectable		 5vunA-2fjaA:
22.29
5vunB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 5vunA-2fjaB:
undetectable
5vunB-2fjaB:
undetectable		 5vunA-2fjaB:
18.25
5vunB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.24A 5vuoA-2fjaA:
undetectable
5vuoB-2fjaA:
undetectable		 5vuoA-2fjaA:
22.29
5vuoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 5vuoA-2fjaA:
undetectable
5vuoB-2fjaA:
undetectable		 5vuoA-2fjaA:
22.29
5vuoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.25A 5vuoA-2fjaA:
undetectable
5vuoB-2fjaA:
undetectable		 5vuoA-2fjaA:
22.29
5vuoB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 5vuoA-2fjaB:
undetectable
5vuoB-2fjaB:
undetectable		 5vuoA-2fjaB:
18.25
5vuoB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.26A 5vupA-2fjaA:
undetectable
5vupB-2fjaA:
undetectable		 5vupA-2fjaA:
22.29
5vupB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5vupA-2fjaA:
undetectable
5vupB-2fjaA:
undetectable		 5vupA-2fjaA:
22.29
5vupB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 5vupA-2fjaB:
undetectable
5vupB-2fjaB:
undetectable		 5vupA-2fjaB:
18.25
5vupB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.24A 5vuqA-2fjaA:
undetectable
5vuqB-2fjaA:
undetectable		 5vuqA-2fjaA:
22.29
5vuqB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5vuqA-2fjaA:
undetectable
5vuqB-2fjaA:
undetectable		 5vuqA-2fjaA:
22.29
5vuqB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.23A 5vuqA-2fjaA:
undetectable
5vuqB-2fjaA:
undetectable		 5vuqA-2fjaA:
22.29
5vuqB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 5vuqA-2fjaB:
undetectable
5vuqB-2fjaB:
undetectable		 5vuqA-2fjaB:
18.25
5vuqB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.25A 5vurA-2fjaA:
undetectable
5vurB-2fjaA:
1.5		 5vurA-2fjaA:
22.29
5vurB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 5vurA-2fjaB:
undetectable
5vurB-2fjaB:
undetectable		 5vurA-2fjaB:
18.25
5vurB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 5vusA-2fjaA:
undetectable
5vusB-2fjaA:
undetectable		 5vusA-2fjaA:
22.29
5vusB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.23A 5vusA-2fjaA:
undetectable
5vusB-2fjaA:
undetectable		 5vusA-2fjaA:
22.29
5vusB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 5vusA-2fjaB:
undetectable
5vusB-2fjaB:
undetectable		 5vusA-2fjaB:
18.25
5vusB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.27A 5vutA-2fjaA:
undetectable
5vutB-2fjaA:
undetectable		 5vutA-2fjaA:
22.29
5vutB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.39A 5vutA-2fjaA:
undetectable
5vutB-2fjaA:
undetectable		 5vutA-2fjaA:
22.29
5vutB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 5vutA-2fjaA:
undetectable
5vutB-2fjaA:
undetectable		 5vutA-2fjaA:
22.29
5vutB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.33A 5vutA-2fjaB:
undetectable
5vutB-2fjaB:
undetectable		 5vutA-2fjaB:
18.25
5vutB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.22A 5vuuA-2fjaA:
undetectable
5vuuB-2fjaA:
undetectable		 5vuuA-2fjaA:
22.29
5vuuB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 5vuuA-2fjaA:
undetectable
5vuuB-2fjaA:
undetectable		 5vuuA-2fjaA:
22.29
5vuuB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.28A 5vuuA-2fjaA:
undetectable
5vuuB-2fjaA:
undetectable		 5vuuA-2fjaA:
22.29
5vuuB-2fjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 5vuuA-2fjaB:
undetectable
5vuuB-2fjaB:
undetectable		 5vuuA-2fjaB:
18.25
5vuuB-2fjaB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5vuvA-2fjaA:
1.6
5vuvB-2fjaA:
0.6		 5vuvA-2fjaA:
22.42
5vuvB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 5vuvA-2fjaB:
undetectable
5vuvB-2fjaB:
undetectable		 5vuvA-2fjaB:
19.00
5vuvB-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.33A 5vuwA-2fjaA:
0.5
5vuwB-2fjaA:
undetectable		 5vuwA-2fjaA:
22.42
5vuwB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 5vuwA-2fjaB:
undetectable
5vuwB-2fjaB:
undetectable		 5vuwA-2fjaB:
19.00
5vuwB-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 5vuxA-2fjaA:
undetectable
5vuxB-2fjaA:
undetectable		 5vuxA-2fjaA:
22.42
5vuxB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.16A 5vuyA-2fjaA:
undetectable
5vuyB-2fjaA:
undetectable		 5vuyA-2fjaA:
22.42
5vuyB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.32A 5vuyA-2fjaA:
undetectable
5vuyB-2fjaA:
undetectable		 5vuyA-2fjaA:
22.42
5vuyB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 5vuyA-2fjaB:
undetectable
5vuyB-2fjaB:
undetectable		 5vuyA-2fjaB:
19.00
5vuyB-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.26A 5vuzA-2fjaA:
0.5
5vuzB-2fjaA:
undetectable		 5vuzA-2fjaA:
22.42
5vuzB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5vuzA-2fjaA:
0.5
5vuzB-2fjaA:
undetectable		 5vuzA-2fjaA:
22.42
5vuzB-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 5vuzA-2fjaB:
undetectable
5vuzB-2fjaB:
undetectable		 5vuzA-2fjaB:
19.00
5vuzB-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 5vv0A-2fjaA:
1.6
5vv0B-2fjaA:
1.6		 5vv0A-2fjaA:
22.86
5vv0B-2fjaA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.24A 5vv0A-2fjaA:
1.6
5vv0B-2fjaA:
1.6		 5vv0A-2fjaA:
22.86
5vv0B-2fjaA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 5vv0A-2fjaB:
undetectable
5vv0B-2fjaB:
undetectable		 5vv0A-2fjaB:
19.00
5vv0B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.24A 5vv1A-2fjaA:
undetectable
5vv1B-2fjaA:
undetectable		 5vv1A-2fjaA:
22.42
5vv1B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 5vv1A-2fjaA:
undetectable
5vv1B-2fjaA:
undetectable		 5vv1A-2fjaA:
22.42
5vv1B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 5vv1A-2fjaB:
undetectable
5vv1B-2fjaB:
undetectable		 5vv1A-2fjaB:
19.00
5vv1B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.27A 5vv2A-2fjaA:
undetectable
5vv2B-2fjaA:
1.5		 5vv2A-2fjaA:
22.42
5vv2B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 5vv2A-2fjaA:
undetectable
5vv2B-2fjaA:
1.5		 5vv2A-2fjaA:
22.42
5vv2B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.26A 5vv2A-2fjaA:
undetectable
5vv2B-2fjaA:
1.5		 5vv2A-2fjaA:
22.42
5vv2B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 5vv2A-2fjaB:
undetectable
5vv2B-2fjaB:
undetectable		 5vv2A-2fjaB:
19.00
5vv2B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 5vv3A-2fjaA:
1.6
5vv3B-2fjaA:
undetectable		 5vv3A-2fjaA:
22.42
5vv3B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 5vv3A-2fjaB:
undetectable
5vv3B-2fjaB:
undetectable		 5vv3A-2fjaB:
19.00
5vv3B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 5vv4A-2fjaB:
undetectable
5vv4B-2fjaB:
undetectable		 5vv4A-2fjaB:
19.00
5vv4B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.19A 5vv5A-2fjaA:
undetectable
5vv5B-2fjaA:
undetectable		 5vv5A-2fjaA:
22.42
5vv5B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.32A 5vv5A-2fjaA:
undetectable
5vv5B-2fjaA:
undetectable		 5vv5A-2fjaA:
22.42
5vv5B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.27A 5vv5A-2fjaA:
undetectable
5vv5B-2fjaA:
undetectable		 5vv5A-2fjaA:
22.42
5vv5B-2fjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.31A 5vv5A-2fjaB:
undetectable
5vv5B-2fjaB:
undetectable		 5vv5A-2fjaB:
19.00
5vv5B-2fjaB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		5 / 12 PHE B 815
ALA A  42
GLY A 456
GLY B 833
PHE A 453
 None
 0.98A 5w4zA-2fjaB:
undetectable		 5w4zA-2fjaB:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		5 / 12 PHE B 815
ALA A  42
GLY A 456
GLY B 833
PHE A 453
 None
 0.96A 5w4zB-2fjaB:
undetectable		 5w4zB-2fjaB:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 180
GLU A 483
VAL A 481
TRP A 572
HIS A 576
 None
 1.28A 5xiqA-2fjaA:
undetectable		 5xiqA-2fjaA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 180
GLU A 483
VAL A 481
TRP A 572
HIS A 576
 None
 1.25A 5xiqB-2fjaA:
undetectable		 5xiqB-2fjaA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 180
GLU A 483
VAL A 481
TRP A 572
HIS A 576
 None
 1.28A 5xiqD-2fjaA:
2.1		 5xiqD-2fjaA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.20A 6auqA-2fjaA:
undetectable
6auqB-2fjaA:
undetectable		 6auqA-2fjaA:
10.61
6auqB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.34A 6auqA-2fjaA:
undetectable
6auqB-2fjaA:
undetectable		 6auqA-2fjaA:
10.61
6auqB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 6auqA-2fjaB:
undetectable
6auqB-2fjaB:
undetectable		 6auqA-2fjaB:
17.65
6auqB-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.33A 6aurA-2fjaA:
undetectable
6aurB-2fjaA:
undetectable		 6aurA-2fjaA:
10.61
6aurB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.32A 6aurA-2fjaA:
undetectable
6aurB-2fjaA:
undetectable		 6aurA-2fjaA:
10.61
6aurB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 6aurA-2fjaB:
undetectable
6aurB-2fjaB:
undetectable		 6aurA-2fjaB:
17.65
6aurB-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.32A 6ausA-2fjaA:
undetectable
6ausB-2fjaA:
undetectable		 6ausA-2fjaA:
10.61
6ausB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 6ausA-2fjaA:
undetectable
6ausB-2fjaA:
undetectable		 6ausA-2fjaA:
10.61
6ausB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.33A 6ausA-2fjaA:
undetectable
6ausB-2fjaA:
undetectable		 6ausA-2fjaA:
10.61
6ausB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.31A 6autA-2fjaA:
undetectable
6autB-2fjaA:
undetectable		 6autA-2fjaA:
10.61
6autB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 6autA-2fjaA:
undetectable
6autB-2fjaA:
undetectable		 6autA-2fjaA:
10.61
6autB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 6autA-2fjaB:
undetectable
6autB-2fjaB:
undetectable		 6autA-2fjaB:
17.65
6autB-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 6auuA-2fjaA:
undetectable
6auuB-2fjaA:
undetectable		 6auuA-2fjaA:
10.61
6auuB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.32A 6auuA-2fjaB:
undetectable
6auuB-2fjaB:
undetectable		 6auuA-2fjaB:
17.65
6auuB-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.33A 6auvA-2fjaA:
0.5
6auvB-2fjaA:
0.5		 6auvA-2fjaA:
10.61
6auvB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 6auvA-2fjaA:
0.5
6auvB-2fjaA:
0.5		 6auvA-2fjaA:
10.61
6auvB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 6auvA-2fjaB:
undetectable
6auvB-2fjaB:
undetectable		 6auvA-2fjaB:
17.65
6auvB-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.24A 6auwA-2fjaA:
undetectable
6auwB-2fjaA:
undetectable		 6auwA-2fjaA:
10.61
6auwB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.38A 6auwA-2fjaA:
undetectable
6auwB-2fjaA:
undetectable		 6auwA-2fjaA:
10.61
6auwB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.30A 6auwA-2fjaA:
undetectable
6auwB-2fjaA:
undetectable		 6auwA-2fjaA:
10.61
6auwB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 6auwA-2fjaB:
undetectable
6auwB-2fjaB:
undetectable		 6auwA-2fjaB:
17.65
6auwB-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 6auxA-2fjaA:
undetectable
6auxB-2fjaA:
undetectable		 6auxA-2fjaA:
10.61
6auxB-2fjaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 6auxA-2fjaB:
undetectable
6auxB-2fjaB:
undetectable		 6auxA-2fjaB:
17.65
6auxB-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.32A 6auyA-2fjaA:
undetectable
6auyB-2fjaA:
undetectable		 6auyA-2fjaA:
7.87
6auyB-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 6auyA-2fjaA:
undetectable
6auyB-2fjaA:
undetectable		 6auyA-2fjaA:
7.87
6auyB-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.30A 6auzA-2fjaA:
undetectable
6auzB-2fjaA:
undetectable		 6auzA-2fjaA:
7.87
6auzB-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 6auzA-2fjaB:
undetectable
6auzB-2fjaB:
undetectable		 6auzA-2fjaB:
17.65
6auzB-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.33A 6av0A-2fjaA:
undetectable
6av0B-2fjaA:
undetectable		 6av0A-2fjaA:
7.87
6av0B-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 6av0A-2fjaA:
undetectable
6av0B-2fjaA:
undetectable		 6av0A-2fjaA:
7.87
6av0B-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.35A 6av0A-2fjaB:
undetectable
6av0B-2fjaB:
undetectable		 6av0A-2fjaB:
17.65
6av0B-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.30A 6av1A-2fjaA:
0.5
6av1B-2fjaA:
undetectable		 6av1A-2fjaA:
7.87
6av1B-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.32A 6av1A-2fjaA:
0.5
6av1B-2fjaA:
undetectable		 6av1A-2fjaA:
7.87
6av1B-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.33A 6av1A-2fjaA:
0.5
6av1B-2fjaA:
undetectable		 6av1A-2fjaA:
7.87
6av1B-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.34A 6av1A-2fjaB:
undetectable
6av1B-2fjaB:
undetectable		 6av1A-2fjaB:
17.65
6av1B-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 6av2A-2fjaA:
0.5
6av2B-2fjaA:
undetectable		 6av2A-2fjaA:
7.87
6av2B-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.36A 6av2A-2fjaB:
undetectable
6av2B-2fjaB:
undetectable		 6av2A-2fjaB:
17.65
6av2B-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.32A 6av3A-2fjaA:
undetectable
6av3B-2fjaA:
undetectable		 6av3A-2fjaA:
7.87
6av3B-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 6av3A-2fjaA:
undetectable
6av3B-2fjaA:
undetectable		 6av3A-2fjaA:
7.87
6av3B-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.31A 6av4A-2fjaA:
undetectable
6av4B-2fjaA:
undetectable		 6av4A-2fjaA:
7.87
6av4B-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.37A 6av4A-2fjaA:
undetectable
6av4B-2fjaA:
undetectable		 6av4A-2fjaA:
7.87
6av4B-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.38A 6av4A-2fjaB:
undetectable
6av4B-2fjaB:
undetectable		 6av4A-2fjaB:
17.65
6av4B-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.35A 6av5A-2fjaA:
undetectable
6av5B-2fjaA:
undetectable		 6av5A-2fjaA:
7.87
6av5B-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 6av5A-2fjaA:
undetectable
6av5B-2fjaA:
undetectable		 6av5A-2fjaA:
7.87
6av5B-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 LEU A 343
LEU A 278
GLY A 142
ARG A  85
 None
 0.81A 6ce2A-2fjaA:
1.4		 6ce2A-2fjaA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.32A 6cicA-2fjaA:
undetectable
6cicB-2fjaA:
undetectable		 6cicA-2fjaA:
7.87
6cicB-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.35A 6cicA-2fjaA:
undetectable
6cicB-2fjaA:
undetectable		 6cicA-2fjaA:
7.87
6cicB-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.31A 6cicA-2fjaA:
undetectable
6cicB-2fjaA:
undetectable		 6cicA-2fjaA:
7.87
6cicB-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 6cicA-2fjaB:
undetectable
6cicB-2fjaB:
undetectable		 6cicA-2fjaB:
17.65
6cicB-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 586
VAL A 578
TRP A 579
GLU A 555
 None
 1.29A 6cidA-2fjaA:
1.6
6cidB-2fjaA:
1.5		 6cidA-2fjaA:
7.87
6cidB-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		4 / 7 ARG A  62
VAL A 367
TRP B 788
GLU A 360
 None
 1.36A 6cidA-2fjaA:
1.6
6cidB-2fjaA:
1.5		 6cidA-2fjaA:
7.87
6cidB-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 555
ARG A 586
VAL A 578
TRP A 579
 None
 1.32A 6cidA-2fjaA:
1.6
6cidB-2fjaA:
1.5		 6cidA-2fjaA:
7.87
6cidB-2fjaA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		4 / 7 TRP B 788
GLU A 360
ARG A  62
VAL A 367
 None
 1.37A 6cidA-2fjaB:
undetectable
6cidB-2fjaB:
undetectable		 6cidA-2fjaB:
17.65
6cidB-2fjaB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		3 / 3 LEU A  54
GLY A 166
PHE B 815
 None
 0.65A 6exiC-2fjaA:
undetectable		 6exiC-2fjaA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA807_0
(GEPHYRIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		4 / 4 PRO B 844
LEU A  79
VAL A 116
ARG A 114
 None
 1.49A 6fgdA-2fjaB:
undetectable		 6fgdA-2fjaB:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 5 ARG A 563
ALA A 562
GLN A 516
ILE A 512
 None
 1.43A 6g9bA-2fjaA:
undetectable
6g9bB-2fjaA:
0.0		 6g9bA-2fjaA:
8.28
6g9bB-2fjaA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_2
(-)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 6 TRP A 596
HIS A 319
ASN A 318
TYR A 599
 None
 1.39A 6gneA-2fjaA:
2.4		 6gneA-2fjaA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 TRP A 234
ASP A 268
ARG A 224
GLU A 391
 FAD  A1000 ( 4.4A)
None
None
None
 1.15A 6mn4A-2fjaA:
undetectable		 6mn4A-2fjaA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		4 / 8 TRP A 234
ASP A 268
ARG A 224
GLU A 391
 FAD  A1000 ( 4.4A)
None
None
None
 1.25A 6mn4B-2fjaA:
undetectable		 6mn4B-2fjaA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 180
GLU A 483
VAL A 481
TRP A 572
HIS A 576
 None
 1.17A 6mn8A-2fjaA:
undetectable		 6mn8A-2fjaA:
21.91