SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E6W_C_ESTC302_1
(SHORT CHAIN
3-HYDROXYACYL-COA
DEHYDROGENASE)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		4 / 4 ALA 1 485
GLN 1 577
TYR 1 574
LEU 1 423
 None
 1.30A 1e6wC-2fji1:
undetectable		 1e6wC-2fji1:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		4 / 4 GLY 1 540
LEU 1 541
GLY 1 539
ARG 1 448
 None
 1.13A 1j7kA-2fji1:
undetectable		 1j7kA-2fji1:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		5 / 9 LEU 1 545
LEU 1 598
LEU 1 600
ILE 1 601
ILE 1 514
 None
 1.16A 2f78A-2fji1:
undetectable		 2f78A-2fji1:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		5 / 9 LEU 1 545
LEU 1 598
LEU 1 600
ILE 1 601
ILE 1 514
 None
 1.18A 2f78B-2fji1:
undetectable		 2f78B-2fji1:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		5 / 9 LEU 1 545
LEU 1 598
LEU 1 600
ILE 1 601
ILE 1 514
 None
 1.16A 2f7aA-2fji1:
undetectable		 2f7aA-2fji1:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		4 / 8 MET 1 717
PHE 1 720
ALA 1 667
LEU 1 668
 None
 0.95A 2o01A-2fji1:
undetectable		 2o01A-2fji1:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		4 / 5 LEU 1 776
ALA 1 772
LEU 1 750
MET 1 795
 None
 1.09A 2oaxA-2fji1:
undetectable		 2oaxA-2fji1:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		4 / 7 ILE 1 546
SER 1 549
PHE 1 652
ILE 1 601
 None
 1.09A 2q6hA-2fji1:
undetectable		 2q6hA-2fji1:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		4 / 7 ILE 1 546
SER 1 549
PHE 1 652
ILE 1 601
 None
 1.11A 2qb4A-2fji1:
undetectable		 2qb4A-2fji1:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		5 / 11 LEU 1 603
GLY 1 599
ILE 1 510
LYS 1 509
SER 1 511
 None
 1.17A 3bjwB-2fji1:
undetectable		 3bjwB-2fji1:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		5 / 12 LEU 1 603
GLY 1 599
ILE 1 510
LYS 1 509
SER 1 511
 None
 1.19A 3bjwF-2fji1:
undetectable		 3bjwF-2fji1:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		5 / 11 LEU 1 603
GLY 1 599
ILE 1 510
LYS 1 509
SER 1 511
 None
 1.13A 3bjwH-2fji1:
undetectable		 3bjwH-2fji1:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		5 / 11 ILE 1 753
MET 1 717
PHE 1 720
ILE 1 615
LEU 1 668
 None
 1.19A 3qg2B-2fji1:
undetectable		 3qg2B-2fji1:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		3 / 3 LYS 1 610
SER 1 624
GLN 1 628
 None
 0.89A 3si7A-2fji1:
undetectable		 3si7A-2fji1:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		5 / 12 SER 1 597
ASN 1 651
ILE 1 653
VAL 1 699
PHE 1 696
 None
 0.98A 4dx5B-2fji1:
4.2		 4dx5B-2fji1:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		6 / 12 SER 1 597
ASN 1 651
ASP 1 654
ILE 1 653
VAL 1 699
PHE 1 696
 None
 1.38A 4u8vB-2fji1:
2.2		 4u8vB-2fji1:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		3 / 3 MET 1 410
GLU 1 414
LEU 1 418
 None
 0.73A 4v2oB-2fji1:
undetectable		 4v2oB-2fji1:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		3 / 3 HIS 1 672
SER 1 673
LYS 1 675
 None
 0.43A 5os7A-2fji1:
undetectable		 5os7A-2fji1:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2fji EXOCYST COMPLEX
COMPONENT SEC6
(Saccharomyces
cerevisiae) 		3 / 3 HIS 1 672
SER 1 673
LYS 1 675
 None
 0.43A 6gmdB-2fji1:
undetectable		 6gmdB-2fji1:
20.85