SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fjl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AVP_A_MV2A313_1 (PANTOTHENATE KINASE)	2fjl	1-PHOSPHATIDYLINOSIT OL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1 (Rattus norvegicus)	4 / 7	VAL A 23 ASP A 80 TYR A 21 ASN A 4	None	1.01A	3avpA-2fjlA: undetectable	3avpA-2fjlA: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L1W_B_STRB402_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	2fjl	1-PHOSPHATIDYLINOSIT OL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1 (Rattus norvegicus)	4 / 6	VAL A 146 VAL A 95 ILE A 29 TRP A 139	None	0.87A	4l1wB-2fjlA: undetectable	4l1wB-2fjlA: 17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z69_A_DIFA1007_1 (SERUM ALBUMIN)	2fjl	1-PHOSPHATIDYLINOSIT OL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1 (Rattus norvegicus)	5 / 9	ARG A 144 LEU A 24 ILE A 29 SER A 27 ALA A 147	None	1.46A	4z69A-2fjlA: undetectable	4z69A-2fjlA: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DQY_A_BEZA401_0 (THIOREDOXIN)	2fjl	1-PHOSPHATIDYLINOSIT OL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1 (Rattus norvegicus)	4 / 8	ILE A 143 VAL A 95 GLN A 148 GLU A 145	None	0.91A	5dqyA-2fjlA: undetectable	5dqyA-2fjlA: 22.97

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3AVP_A_MV2A313_1","PANTOTHENATE KINASE","2fjl","1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1","Rattus norvegicus",4,"VAL A  23;ASP A  80;TYR A  21;ASN A   4","None","1.01A","3avpA-2fjlA:undetectable","3avpA-2fjlA:19.59"],["4L1W_B_STRB402_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","2fjl","1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1","Rattus norvegicus",4,"VAL A 146;VAL A  95;ILE A  29;TRP A 139","None","0.87A","4l1wB-2fjlA:undetectable","4l1wB-2fjlA:17.33"],["4Z69_A_DIFA1007_1","SERUM ALBUMIN","2fjl","1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1","Rattus norvegicus",5,"ARG A 144;LEU A  24;ILE A  29;SER A  27;ALA A 147","None","1.46A","4z69A-2fjlA:undetectable","4z69A-2fjlA:13.64"],["5DQY_A_BEZA401_0","THIOREDOXIN","2fjl","1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1","Rattus norvegicus",4,"ILE A 143;VAL A  95;GLN A 148;GLU A 145","None","0.91A","5dqyA-2fjlA:undetectable","5dqyA-2fjlA:22.97"]]