SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fk6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.40A 1c9sA-2fk6A:
undetectable
1c9sK-2fk6A:
undetectable		 1c9sA-2fk6A:
12.30
1c9sK-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 THR A  20
GLY A 210
HIS A 269
ALA A  65
THR A  62
 None
None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
 1.41A 1c9sB-2fk6A:
undetectable
1c9sC-2fk6A:
undetectable		 1c9sB-2fk6A:
12.30
1c9sC-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.39A 1c9sO-2fk6A:
undetectable
1c9sP-2fk6A:
undetectable		 1c9sO-2fk6A:
12.30
1c9sP-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.37A 1c9sR-2fk6A:
0.0
1c9sS-2fk6A:
0.0		 1c9sR-2fk6A:
12.30
1c9sS-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 THR A  20
GLY A 210
HIS A 269
ALA A  65
THR A  62
 None
None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
 1.44A 1gtfB-2fk6A:
undetectable
1gtfC-2fk6A:
undetectable		 1gtfB-2fk6A:
12.30
1gtfC-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.44A 1gtfM-2fk6A:
undetectable
1gtfN-2fk6A:
0.0		 1gtfM-2fk6A:
12.30
1gtfN-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 THR A  20
GLY A 210
HIS A 269
ALA A  65
THR A  62
 None
None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
 1.38A 1gtnG-2fk6A:
undetectable
1gtnH-2fk6A:
undetectable		 1gtnG-2fk6A:
12.30
1gtnH-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 8 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.44A 1gtnP-2fk6A:
undetectable
1gtnQ-2fk6A:
undetectable		 1gtnP-2fk6A:
12.30
1gtnQ-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.42A 1gtnQ-2fk6A:
undetectable
1gtnR-2fk6A:
undetectable		 1gtnQ-2fk6A:
12.30
1gtnR-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.39A 1gtnS-2fk6A:
undetectable
1gtnT-2fk6A:
undetectable		 1gtnS-2fk6A:
12.30
1gtnT-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		3 / 3 PHE A 131
TRP A  34
GLU A  57
 None
None
MES  A 801 (-4.3A)
 1.18A 1mogA-2fk6A:
undetectable		 1mogA-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		4 / 4 LEU A   3
VAL A 206
CYH A 225
ALA A 222
 None
 1.13A 1mz9E-2fk6A:
undetectable		 1mz9E-2fk6A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		3 / 3 ASP A 211
HIS A 269
HIS A 247
 ZN  A 401 (-2.6A)
ZN  A 401 (-3.6A)
None
 0.64A 1oe1A-2fk6A:
undetectable		 1oe1A-2fk6A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		3 / 3 ASP A 211
HIS A 269
HIS A 247
 ZN  A 401 (-2.6A)
ZN  A 401 (-3.6A)
None
 0.64A 1oe3A-2fk6A:
undetectable		 1oe3A-2fk6A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.36A 1utdA-2fk6A:
undetectable
1utdB-2fk6A:
undetectable		 1utdA-2fk6A:
12.30
1utdB-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.42A 1utdD-2fk6A:
undetectable
1utdE-2fk6A:
undetectable		 1utdD-2fk6A:
12.30
1utdE-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.38A 1utdG-2fk6A:
undetectable
1utdH-2fk6A:
undetectable		 1utdG-2fk6A:
12.30
1utdH-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.45A 1utdR-2fk6A:
undetectable
1utdS-2fk6A:
undetectable		 1utdR-2fk6A:
12.30
1utdS-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 6 ILE A 266
VAL A 229
VAL A  90
ILE A  56
ASP A  37
 None
 1.48A 1uwhB-2fk6A:
undetectable		 1uwhB-2fk6A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		4 / 7 THR A 268
HIS A 269
GLY A   7
ASP A 298
 None
ZN  A 401 (-3.6A)
None
None
 1.03A 2ddwB-2fk6A:
undetectable		 2ddwB-2fk6A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		4 / 5 LEU A 111
ILE A 100
ILE A 117
ALA A 116
 None
 0.67A 2i2zA-2fk6A:
undetectable		 2i2zA-2fk6A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		4 / 4 LEU A 111
ILE A 100
ILE A 117
ALA A 116
 None
 0.72A 2i30A-2fk6A:
undetectable		 2i30A-2fk6A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		6 / 12 ASP A 298
LEU A   6
GLY A   7
GLY A   9
ASP A  67
LEU A  35
 None
None
None
None
ZN  A 401 (-2.6A)
None
 1.37A 2nxeA-2fk6A:
undetectable		 2nxeA-2fk6A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		4 / 5 ALA A 232
ALA A 257
ALA A 262
VAL A 207
 None
 0.87A 2nyrB-2fk6A:
undetectable		 2nyrB-2fk6A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 11 ASP A  67
HIS A  68
HIS A 140
ASP A 211
HIS A 269
 ZN  A 401 (-2.6A)
ZN  A 401 (-3.4A)
None
ZN  A 401 (-2.6A)
ZN  A 401 (-3.6A)
 0.75A 2q0jB-2fk6A:
10.8		 2q0jB-2fk6A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		3 / 3 SER A 293
HIS A 269
ASP A  37
 None
ZN  A 401 (-3.6A)
None
 0.64A 2wa2B-2fk6A:
undetectable		 2wa2B-2fk6A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		3 / 3 ASP A 211
HIS A 269
HIS A 247
 ZN  A 401 (-2.6A)
ZN  A 401 (-3.6A)
None
 0.64A 2xxgA-2fk6A:
undetectable		 2xxgA-2fk6A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		3 / 3 ASP A 211
HIS A 269
HIS A 247
 ZN  A 401 (-2.6A)
ZN  A 401 (-3.6A)
None
 0.66A 2xxgC-2fk6A:
undetectable		 2xxgC-2fk6A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		4 / 8 GLN A 150
ARG A 148
ILE A 132
ASP A 153
 None
GOL  A 501 ( 4.0A)
None
None
 1.07A 2xytE-2fk6A:
undetectable		 2xytE-2fk6A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		4 / 8 GLN A 150
ARG A 148
ILE A 132
ASP A 153
 None
GOL  A 501 ( 4.0A)
None
None
 1.05A 2xytH-2fk6A:
undetectable		 2xytH-2fk6A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		4 / 5 LEU A  72
GLY A  74
GLU A  40
CYH A  38
 None
 1.21A 3aiaA-2fk6A:
undetectable
3aiaB-2fk6A:
undetectable		 3aiaA-2fk6A:
19.55
3aiaB-2fk6A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 8 LEU A  35
GLY A  71
VAL A  90
GLY A  77
ILE A  59
 None
 1.17A 3ekpA-2fk6A:
undetectable		 3ekpA-2fk6A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 12 LEU A  35
GLY A  39
VAL A  90
ILE A 100
ILE A  59
 None
 0.87A 3pwrB-2fk6A:
undetectable		 3pwrB-2fk6A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 12 LEU A  72
LEU A  75
LEU A  88
ILE A  96
ILE A 117
 None
 0.77A 4j24A-2fk6A:
undetectable		 4j24A-2fk6A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 11 HIS A  63
ASP A  67
HIS A  68
HIS A 140
HIS A 269
 None
ZN  A 401 (-2.6A)
ZN  A 401 (-3.4A)
None
ZN  A 401 (-3.6A)
 0.48A 5ayaA-2fk6A:
11.6		 5ayaA-2fk6A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 THR A  20
GLY A 210
HIS A 269
ALA A  65
THR A  62
 None
None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
 1.43A 5eeuA-2fk6A:
undetectable
5eeuB-2fk6A:
undetectable		 5eeuA-2fk6A:
12.30
5eeuB-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.43A 5eeuL-2fk6A:
0.0
5eeuM-2fk6A:
0.0		 5eeuL-2fk6A:
12.30
5eeuM-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eeuR-2fk6A:
undetectable
5eeuS-2fk6A:
undetectable		 5eeuR-2fk6A:
12.30
5eeuS-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eeuT-2fk6A:
undetectable
5eeuU-2fk6A:
undetectable		 5eeuT-2fk6A:
12.30
5eeuU-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.43A 5eevL-2fk6A:
undetectable
5eevM-2fk6A:
0.0		 5eevL-2fk6A:
12.30
5eevM-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eevR-2fk6A:
undetectable
5eevS-2fk6A:
undetectable		 5eevR-2fk6A:
12.30
5eevS-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eevT-2fk6A:
undetectable
5eevU-2fk6A:
undetectable		 5eevT-2fk6A:
12.30
5eevU-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 THR A  20
GLY A 210
HIS A 269
ALA A  65
THR A  62
 None
None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
 1.40A 5eewJ-2fk6A:
undetectable
5eewK-2fk6A:
undetectable		 5eewJ-2fk6A:
12.30
5eewK-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.43A 5eewL-2fk6A:
undetectable
5eewM-2fk6A:
0.0		 5eewL-2fk6A:
12.30
5eewM-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eewR-2fk6A:
undetectable
5eewS-2fk6A:
undetectable		 5eewR-2fk6A:
12.30
5eewS-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eewT-2fk6A:
undetectable
5eewU-2fk6A:
undetectable		 5eewT-2fk6A:
12.30
5eewU-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.43A 5eexL-2fk6A:
0.0
5eexM-2fk6A:
0.0		 5eexL-2fk6A:
12.30
5eexM-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.40A 5eexQ-2fk6A:
undetectable
5eexR-2fk6A:
undetectable		 5eexQ-2fk6A:
12.30
5eexR-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eexR-2fk6A:
undetectable
5eexS-2fk6A:
undetectable		 5eexR-2fk6A:
12.30
5eexS-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eexT-2fk6A:
undetectable
5eexU-2fk6A:
undetectable		 5eexT-2fk6A:
12.30
5eexU-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.43A 5eeyL-2fk6A:
undetectable
5eeyM-2fk6A:
0.0		 5eeyL-2fk6A:
12.30
5eeyM-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eeyQ-2fk6A:
undetectable
5eeyR-2fk6A:
undetectable		 5eeyQ-2fk6A:
12.30
5eeyR-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eeyR-2fk6A:
undetectable
5eeyS-2fk6A:
undetectable		 5eeyR-2fk6A:
12.30
5eeyS-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eeyT-2fk6A:
undetectable
5eeyU-2fk6A:
undetectable		 5eeyT-2fk6A:
12.30
5eeyU-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 THR A  20
GLY A 210
HIS A 269
ALA A  65
THR A  62
 None
None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
 1.40A 5eezJ-2fk6A:
undetectable
5eezK-2fk6A:
undetectable		 5eezJ-2fk6A:
12.30
5eezK-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.43A 5eezL-2fk6A:
0.0
5eezM-2fk6A:
0.0		 5eezL-2fk6A:
12.30
5eezM-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eezQ-2fk6A:
undetectable
5eezR-2fk6A:
undetectable		 5eezQ-2fk6A:
12.30
5eezR-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eezR-2fk6A:
undetectable
5eezS-2fk6A:
undetectable		 5eezR-2fk6A:
12.30
5eezS-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5eezT-2fk6A:
undetectable
5eezU-2fk6A:
undetectable		 5eezT-2fk6A:
12.30
5eezU-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 THR A  20
GLY A 210
HIS A 269
ALA A  65
THR A  62
 None
None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
 1.40A 5ef0J-2fk6A:
undetectable
5ef0K-2fk6A:
undetectable		 5ef0J-2fk6A:
12.30
5ef0K-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.43A 5ef0L-2fk6A:
0.0
5ef0M-2fk6A:
0.0		 5ef0L-2fk6A:
12.30
5ef0M-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5ef0Q-2fk6A:
undetectable
5ef0R-2fk6A:
undetectable		 5ef0Q-2fk6A:
12.30
5ef0R-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5ef0R-2fk6A:
undetectable
5ef0S-2fk6A:
undetectable		 5ef0R-2fk6A:
12.30
5ef0S-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.42A 5ef0T-2fk6A:
undetectable
5ef0U-2fk6A:
undetectable		 5ef0T-2fk6A:
12.30
5ef0U-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 THR A  20
GLY A 210
HIS A 269
ALA A  65
THR A  62
 None
None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
 1.41A 5ef1J-2fk6A:
undetectable
5ef1K-2fk6A:
undetectable		 5ef1J-2fk6A:
12.30
5ef1K-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.43A 5ef1L-2fk6A:
0.0
5ef1M-2fk6A:
undetectable		 5ef1L-2fk6A:
12.30
5ef1M-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5ef1Q-2fk6A:
undetectable
5ef1R-2fk6A:
undetectable		 5ef1Q-2fk6A:
12.30
5ef1R-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5ef1R-2fk6A:
undetectable
5ef1S-2fk6A:
undetectable		 5ef1R-2fk6A:
12.30
5ef1S-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.42A 5ef1T-2fk6A:
undetectable
5ef1U-2fk6A:
undetectable		 5ef1T-2fk6A:
12.30
5ef1U-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 THR A  20
GLY A 210
HIS A 269
ALA A  65
THR A  62
 None
None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
 1.40A 5ef2J-2fk6A:
undetectable
5ef2K-2fk6A:
undetectable		 5ef2J-2fk6A:
12.30
5ef2K-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.43A 5ef2L-2fk6A:
0.0
5ef2M-2fk6A:
0.0		 5ef2L-2fk6A:
12.30
5ef2M-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5ef2Q-2fk6A:
undetectable
5ef2R-2fk6A:
undetectable		 5ef2Q-2fk6A:
12.30
5ef2R-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.42A 5ef2R-2fk6A:
undetectable
5ef2S-2fk6A:
undetectable		 5ef2R-2fk6A:
12.30
5ef2S-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.42A 5ef2T-2fk6A:
undetectable
5ef2U-2fk6A:
undetectable		 5ef2T-2fk6A:
12.30
5ef2U-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 THR A  20
GLY A 210
HIS A 269
ALA A  65
THR A  62
 None
None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
 1.41A 5ef3J-2fk6A:
undetectable
5ef3K-2fk6A:
undetectable		 5ef3J-2fk6A:
12.30
5ef3K-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.43A 5ef3L-2fk6A:
0.0
5ef3M-2fk6A:
undetectable		 5ef3L-2fk6A:
12.30
5ef3M-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 9 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.41A 5ef3Q-2fk6A:
undetectable
5ef3R-2fk6A:
undetectable		 5ef3Q-2fk6A:
12.30
5ef3R-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.42A 5ef3R-2fk6A:
undetectable
5ef3S-2fk6A:
undetectable		 5ef3R-2fk6A:
12.30
5ef3S-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 GLY A 210
HIS A 269
ALA A  65
THR A  62
THR A  20
 None
ZN  A 401 (-3.6A)
ZN  A 401 ( 4.9A)
None
None
 1.42A 5ef3T-2fk6A:
undetectable
5ef3U-2fk6A:
undetectable		 5ef3T-2fk6A:
12.30
5ef3U-2fk6A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		4 / 8 ASP A 211
HIS A 269
HIS A 247
HIS A  63
 ZN  A 401 (-2.6A)
ZN  A 401 (-3.6A)
None
None
 0.92A 5nekD-2fk6A:
undetectable		 5nekD-2fk6A:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 HIS A  63
HIS A  68
HIS A 140
ASP A 211
HIS A 247
 None
ZN  A 401 (-3.4A)
None
ZN  A 401 (-2.6A)
None
 0.40A 5nzwA-2fk6A:
12.2		 5nzwA-2fk6A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		5 / 10 HIS A 140
HIS A  63
HIS A 247
ASP A 211
HIS A 269
 None
None
None
ZN  A 401 (-2.6A)
ZN  A 401 (-3.6A)
 1.01A 5nzwA-2fk6A:
12.2		 5nzwA-2fk6A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2fk6 RIBONUCLEASE Z
(Bacillus
subtilis) 		4 / 7 HIS A  63
THR A  20
HIS A 140
LEU A   3
 None
 1.15A 5x1bA-2fk6A:
undetectable
5x1bC-2fk6A:
undetectable
5x1bP-2fk6A:
undetectable		 5x1bA-2fk6A:
20.39
5x1bC-2fk6A:
22.39
5x1bP-2fk6A:
22.39