SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fkk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 2fkk BASEPLATE STRUCTURAL
PROTEIN GP10
(Escherichia
virus
T4) 		4 / 7 GLY A 518
GLY A 517
ASN A 502
PHE A 481
 None
 0.74A 2c49B-2fkkA:
undetectable		 2c49B-2fkkA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2fkk BASEPLATE STRUCTURAL
PROTEIN GP10
(Escherichia
virus
T4) 		4 / 8 ASN A 502
GLY A 517
PHE A 481
ILE A 428
 None
 0.79A 4fglD-2fkkA:
undetectable		 4fglD-2fkkA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2fkk BASEPLATE STRUCTURAL
PROTEIN GP10
(Escherichia
virus
T4) 		4 / 7 ASN A 502
GLY A 517
PHE A 481
ILE A 428
 None
 0.80A 4fglC-2fkkA:
undetectable		 4fglC-2fkkA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 2fkk BASEPLATE STRUCTURAL
PROTEIN GP10
(Escherichia
virus
T4) 		3 / 3 THR A 576
ASN A 577
SER A 578
 PO3  A 710 ( 4.1A)
None
None
 0.63A 4tvtA-2fkkA:
undetectable		 4tvtA-2fkkA:
20.98