SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2flh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FIQ_C_SALC1335_1 (XANTHINE OXIDASE)	2flh	CYTOKININ-SPECIFIC BINDING PROTEIN (Vigna radiata)	4 / 8	LEU A 146 ARG A 144 THR A 9 VAL A 114	None	0.90A	1fiqC-2flhA: undetectable	1fiqC-2flhA: 12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MZ9_D_VDYD1001_3 (CARTILAGE OLIGOMERIC MATRIX PROTEIN)	2flh	CYTOKININ-SPECIFIC BINDING PROTEIN (Vigna radiata)	3 / 3	THR A 139 LEU A 143 LEU A 150	ZEA A 701 (-3.1A) None None	0.64A	1mz9C-2flhA: undetectable	1mz9C-2flhA: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AX9_A_SALA1341_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	2flh	CYTOKININ-SPECIFIC BINDING PROTEIN (Vigna radiata)	4 / 8	LEU A 146 ARG A 144 THR A 9 VAL A 114	None	0.97A	3ax9A-2flhA: undetectable	3ax9A-2flhA: 9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VEU_A_RITA602_2 (CYTOCHROME P450 3A5)	2flh	CYTOKININ-SPECIFIC BINDING PROTEIN (Vigna radiata)	3 / 3	ARG A 144 PHE A 26 LEU A 34	None ZEA A 701 (-3.5A) ZEA A 702 (-4.9A)	0.85A	5veuA-2flhA: undetectable	5veuA-2flhA: 16.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FIQ_C_SALC1335_1","XANTHINE OXIDASE","2flh","CYTOKININ-SPECIFIC BINDING PROTEIN","Vigna radiata",4,"LEU A 146;ARG A 144;THR A   9;VAL A 114","None","0.90A","1fiqC-2flhA:undetectable","1fiqC-2flhA:12.99"],["1MZ9_D_VDYD1001_3","CARTILAGE OLIGOMERIC MATRIX PROTEIN;CARTILAGE OLIGOMERIC MATRIX PROTEIN","2flh","CYTOKININ-SPECIFIC BINDING PROTEIN","Vigna radiata",3,"THR A 139;LEU A 143;LEU A 150","ZEA A 701 (-3.1A);None;None","0.64A","1mz9C-2flhA:undetectable","1mz9C-2flhA:16.96"],["3AX9_A_SALA1341_1","XANTHINE DEHYDROGENASE\/OXIDASE","2flh","CYTOKININ-SPECIFIC BINDING PROTEIN","Vigna radiata",4,"LEU A 146;ARG A 144;THR A   9;VAL A 114","None","0.97A","3ax9A-2flhA:undetectable","3ax9A-2flhA:9.02"],["5VEU_A_RITA602_2","CYTOCHROME P450 3A5","2flh","CYTOKININ-SPECIFIC BINDING PROTEIN","Vigna radiata",3,"ARG A 144;PHE A  26;LEU A  34","None;ZEA A 701 (-3.5A);ZEA A 702 (-4.9A)","0.85A","5veuA-2flhA:undetectable","5veuA-2flhA:16.03"]]