SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fm9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2fm9 CELL INVASION
PROTEIN SIPA
(Salmonella
enterica) 		4 / 7 GLU A 156
LEU A 152
LEU A 142
GLY A 139
 None
 0.90A 1mt1H-2fm9A:
undetectable
1mt1K-2fm9A:
undetectable		 1mt1H-2fm9A:
26.63
1mt1K-2fm9A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2fm9 CELL INVASION
PROTEIN SIPA
(Salmonella
enterica) 		4 / 8 LEU A 222
VAL A 219
VAL A 183
VAL A 179
 None
 0.91A 1t86A-2fm9A:
undetectable		 1t86A-2fm9A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 2fm9 CELL INVASION
PROTEIN SIPA
(Salmonella
enterica) 		5 / 9 PHE A  67
GLY A  70
ILE A 128
ALA A  75
VAL A  79
 None
 1.37A 2drdA-2fm9A:
undetectable		 2drdA-2fm9A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2fm9 CELL INVASION
PROTEIN SIPA
(Salmonella
enterica) 		5 / 9 LEU A 222
LEU A 171
LEU A 178
ASN A 177
ILE A 163
 None
 1.16A 3wdmC-2fm9A:
undetectable		 3wdmC-2fm9A:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2fm9 CELL INVASION
PROTEIN SIPA
(Salmonella
enterica) 		4 / 4 ASN A  85
GLY A  88
ASP A  72
ASP A 130
 None
 1.26A 4n49A-2fm9A:
undetectable		 4n49A-2fm9A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 2fm9 CELL INVASION
PROTEIN SIPA
(Salmonella
enterica) 		5 / 11 VAL A 179
ILE A 261
ILE A 187
PHE A 258
LEU A 254
 None
 1.12A 5e4dB-2fm9A:
undetectable		 5e4dB-2fm9A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 2fm9 CELL INVASION
PROTEIN SIPA
(Salmonella
enterica) 		4 / 8 VAL A 257
GLY A 120
GLN A 126
THR A 124
 None
 0.93A 5sxqA-2fm9A:
undetectable		 5sxqA-2fm9A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 2fm9 CELL INVASION
PROTEIN SIPA
(Salmonella
enterica) 		4 / 8 VAL A 257
GLY A 120
GLN A 126
THR A 124
 None
 0.92A 5sxtA-2fm9A:
undetectable		 5sxtA-2fm9A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 2fm9 CELL INVASION
PROTEIN SIPA
(Salmonella
enterica) 		4 / 8 VAL A 257
GLY A 120
GLN A 126
THR A 124
 None
 0.93A 5sxtB-2fm9A:
undetectable		 5sxtB-2fm9A:
15.09