SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans)
4 / 4 HIS A  82
LEU A 121
LEU A 124
LEU A  61
HEM  A 300 (-3.3A)
HEM  A 300 ( 4.7A)
None
None
1.23A 1a4lD-2fmyA:
undetectable
1a4lD-2fmyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans)
5 / 10 LEU A 206
ARG A 200
LEU A 148
LEU A 214
ILE A 197
None
1.13A 2bxeB-2fmyA:
undetectable
2bxeB-2fmyA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans)
5 / 11 LEU A 208
LEU A 148
SER A 186
LEU A 189
LEU A 206
None
1.08A 2ceoA-2fmyA:
undetectable
2ceoA-2fmyA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans)
4 / 6 LEU A 135
PHE A  68
LEU A  61
ASP A  65
None
1.05A 2wm3A-2fmyA:
undetectable
2wm3A-2fmyA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans)
3 / 3 LEU A 198
THR A 130
ASN A 133
None
0.50A 6baaE-2fmyA:
undetectable
6baaE-2fmyA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans)
3 / 3 LEU A 214
THR A 130
ASN A 133
None
0.73A 6baaE-2fmyA:
undetectable
6baaE-2fmyA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans)
3 / 3 LEU A 198
THR A 130
ASN A 133
None
0.50A 6baaF-2fmyA:
undetectable
6baaF-2fmyA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans)
3 / 3 LEU A 214
THR A 130
ASN A 133
None
0.73A 6baaF-2fmyA:
undetectable
6baaF-2fmyA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans)
3 / 3 LEU A 198
THR A 130
ASN A 133
None
0.51A 6baaG-2fmyA:
undetectable
6baaG-2fmyA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans)
3 / 3 LEU A 214
THR A 130
ASN A 133
None
0.73A 6baaG-2fmyA:
undetectable
6baaG-2fmyA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans)
3 / 3 LEU A 198
THR A 130
ASN A 133
None
0.51A 6baaH-2fmyA:
undetectable
6baaH-2fmyA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans)
3 / 3 LEU A 214
THR A 130
ASN A 133
None
0.73A 6baaH-2fmyA:
undetectable
6baaH-2fmyA:
9.02