SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fnu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 TYR A 316
HIS A 157
THR A  79
ASN A 108
 UD1  A 902 ( 4.5A)
PMP  A 901 (-3.9A)
None
None
 1.30A 1afsA-2fnuA:
undetectable		 1afsA-2fnuA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 TYR A 316
HIS A 157
THR A  79
ASN A 108
 UD1  A 902 ( 4.5A)
PMP  A 901 (-3.9A)
None
None
 1.29A 1afsB-2fnuA:
undetectable		 1afsB-2fnuA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		5 / 10 LEU A  45
ALA A  56
ALA A 192
VAL A  47
ASP A 129
 None
PMP  A 901 (-3.3A)
None
None
None
 1.11A 1rlbE-2fnuA:
undetectable		 1rlbE-2fnuA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 8 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.82A 1v54C-2fnuA:
undetectable
1v54J-2fnuA:
undetectable		 1v54C-2fnuA:
20.38
1v54J-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 8 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.86A 1v54P-2fnuA:
undetectable
1v54W-2fnuA:
undetectable		 1v54P-2fnuA:
20.38
1v54W-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_B_VDNB102_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		5 / 12 TYR A 325
LEU A  91
ASN A  89
ILE A 319
SER A 336
 None
 1.40A 1xotB-2fnuA:
undetectable		 1xotB-2fnuA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		5 / 12 LEU A 152
ALA A 172
LEU A 200
MET A 204
THR A  87
 None
None
None
None
PMP  A 901 (-4.6A)
 1.29A 2aa6A-2fnuA:
undetectable		 2aa6A-2fnuA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 8 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.83A 2dyrC-2fnuA:
undetectable
2dyrJ-2fnuA:
undetectable		 2dyrC-2fnuA:
20.38
2dyrJ-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 8 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.84A 2dyrP-2fnuA:
undetectable
2dyrW-2fnuA:
undetectable		 2dyrP-2fnuA:
20.38
2dyrW-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.89A 2eikC-2fnuA:
undetectable
2eikJ-2fnuA:
undetectable		 2eikC-2fnuA:
20.38
2eikJ-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 8 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.83A 2eikP-2fnuA:
undetectable
2eikW-2fnuA:
undetectable		 2eikP-2fnuA:
20.38
2eikW-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 8 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.89A 2eilC-2fnuA:
undetectable
2eilJ-2fnuA:
undetectable		 2eilC-2fnuA:
20.38
2eilJ-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 8 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.87A 2eilP-2fnuA:
undetectable
2eilW-2fnuA:
undetectable		 2eilP-2fnuA:
20.38
2eilW-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.81A 3ag2C-2fnuA:
undetectable		 3ag2C-2fnuA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.83A 3ag2P-2fnuA:
undetectable
3ag2W-2fnuA:
undetectable		 3ag2P-2fnuA:
20.38
3ag2W-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 8 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.84A 3ag4C-2fnuA:
undetectable
3ag4J-2fnuA:
undetectable		 3ag4C-2fnuA:
20.38
3ag4J-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.86A 3ag4P-2fnuA:
undetectable
3ag4W-2fnuA:
undetectable		 3ag4P-2fnuA:
20.38
3ag4W-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.87A 3asnC-2fnuA:
undetectable
3asnJ-2fnuA:
undetectable		 3asnC-2fnuA:
20.38
3asnJ-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 8 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.83A 3asoC-2fnuA:
undetectable
3asoJ-2fnuA:
undetectable		 3asoC-2fnuA:
20.38
3asoJ-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		5 / 12 VAL A  52
ALA A  50
LEU A  45
PHE A  37
ILE A 185
 None
 1.09A 3hj3D-2fnuA:
undetectable		 3hj3D-2fnuA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		5 / 12 ALA A 192
LEU A  45
LEU A  41
GLY A 160
ALA A 158
 None
 1.24A 3lbdA-2fnuA:
undetectable		 3lbdA-2fnuA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		5 / 12 TYR A 130
ILE A  82
SER A 346
LEU A 347
LEU A 302
 None
 0.93A 3w68B-2fnuA:
undetectable		 3w68B-2fnuA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.70A 3x2qP-2fnuA:
undetectable
3x2qW-2fnuA:
undetectable		 3x2qP-2fnuA:
20.38
3x2qW-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 5 THR A  80
ILE A 109
GLU A 111
PHE A 151
 None
 1.44A 4acbC-2fnuA:
undetectable		 4acbC-2fnuA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 6 PHE A 177
GLY A 170
LEU A  45
VAL A  47
 None
 0.99A 4dubA-2fnuA:
undetectable		 4dubA-2fnuA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8W_G_MTXG301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		5 / 9 PHE A 151
GLY A  46
GLY A 169
CYH A  42
LEU A  45
 None
 1.40A 4l8wG-2fnuA:
2.7		 4l8wG-2fnuA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 8 PHE A 179
ALA A 246
LEU A 243
GLY A 239
 None
 0.97A 4xk8a-2fnuA:
undetectable		 4xk8a-2fnuA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 5 PHE A 264
PHE A 369
PHE A 270
VAL A 365
 None
 1.07A 5a1rA-2fnuA:
undetectable		 5a1rA-2fnuA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.79A 5b1aC-2fnuA:
undetectable
5b1aJ-2fnuA:
undetectable		 5b1aC-2fnuA:
20.38
5b1aJ-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.70A 5b1aP-2fnuA:
undetectable
5b1aW-2fnuA:
undetectable		 5b1aP-2fnuA:
20.38
5b1aW-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.78A 5b1bP-2fnuA:
undetectable
5b1bW-2fnuA:
undetectable		 5b1bP-2fnuA:
20.38
5b1bW-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.71A 5b3sC-2fnuA:
undetectable
5b3sJ-2fnuA:
undetectable		 5b3sC-2fnuA:
20.38
5b3sJ-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.70A 5b3sP-2fnuA:
undetectable		 5b3sP-2fnuA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 PRO A 348
ILE A 288
VAL A 365
ILE A 361
 None
 0.79A 5bmvC-2fnuA:
undetectable		 5bmvC-2fnuA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.72A 5iy5C-2fnuA:
undetectable
5iy5J-2fnuA:
undetectable		 5iy5C-2fnuA:
20.38
5iy5J-2fnuA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		3 / 3 LYS A 183
HIS A 157
HIS A 284
 UD1  A 902 ( 3.3A)
PMP  A 901 (-3.9A)
None
 1.40A 5oexA-2fnuA:
undetectable		 5oexA-2fnuA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		3 / 3 LYS A 183
HIS A 157
HIS A 284
 UD1  A 902 ( 3.3A)
PMP  A 901 (-3.9A)
None
 1.43A 5oexB-2fnuA:
undetectable		 5oexB-2fnuA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		3 / 3 LYS A 183
HIS A 157
HIS A 284
 UD1  A 902 ( 3.3A)
PMP  A 901 (-3.9A)
None
 1.42A 5oexC-2fnuA:
undetectable		 5oexC-2fnuA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		3 / 3 LYS A 183
HIS A 157
HIS A 284
 UD1  A 902 ( 3.3A)
PMP  A 901 (-3.9A)
None
 1.36A 5oexD-2fnuA:
undetectable		 5oexD-2fnuA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.76A 5z84C-2fnuA:
undetectable
5z84J-2fnuA:
undetectable		 5z84C-2fnuA:
20.38
5z84J-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 LEU A 243
GLN A 242
PHE A  37
LEU A  41
 None
 0.73A 5zcqC-2fnuA:
undetectable
5zcqJ-2fnuA:
undetectable		 5zcqC-2fnuA:
20.38
5zcqJ-2fnuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9H_R_ADNR400_1
(CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		5 / 10 VAL A 365
THR A 368
GLU A 344
MET A 290
LEU A 302
 None
 1.32A 6d9hR-2fnuA:
undetectable		 6d9hR-2fnuA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 8 ASN A  66
PHE A 229
HIS A 227
SER A  94
 None
 1.17A 6huoC-2fnuA:
undetectable
6huoD-2fnuA:
undetectable		 6huoC-2fnuA:
11.72
6huoD-2fnuA:
10.93