SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fo1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
4 / 5 ASP E1274
ASP E1271
LEU E1280
ALA E1272
None
1.03A 1nh8A-2fo1E:
undetectable
1nh8A-2fo1E:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
3 / 3 ASP E1139
ARG E1107
ASP E1177
None
0.77A 1vptA-2fo1E:
undetectable
1vptA-2fo1E:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
5 / 10 LYS E1236
ALA E1215
ALA E1210
LEU E1167
LEU E1247
None
1.14A 2bxqA-2fo1E:
undetectable
2bxqA-2fo1E:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
5 / 11 LEU E1113
LEU E1100
ALA E1061
LEU E1057
ALA E1089
None
1.27A 3e22B-2fo1E:
undetectable
3e22B-2fo1E:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
5 / 11 LEU E1109
LEU E1100
ALA E1061
LEU E1057
ALA E1089
None
1.24A 3e22D-2fo1E:
undetectable
3e22D-2fo1E:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
5 / 11 LEU E1113
LEU E1100
ALA E1061
LEU E1057
ALA E1089
None
1.28A 3e22D-2fo1E:
undetectable
3e22D-2fo1E:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
4 / 7 GLU E1203
TYR E1123
GLU E1127
TYR E1205
None
1.33A 3ku9B-2fo1E:
undetectable
3ku9B-2fo1E:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
4 / 5 LEU E1131
ALA E1136
MET E1099
ASN E1124
None
1.31A 3uq6A-2fo1E:
undetectable
3uq6A-2fo1E:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
3 / 3 ARG E1138
ASP E1177
ARG E1176
None
0.65A 4wq4B-2fo1E:
undetectable
4wq4B-2fo1E:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
5 / 12 LEU E1113
LEU E1100
ALA E1061
LEU E1057
ALA E1089
None
1.08A 5mioB-2fo1E:
undetectable
5mioB-2fo1E:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
3 / 3 LYS E1242
LEU E1247
ARG E1208
None
0.91A 5yw0A-2fo1E:
undetectable
5yw0A-2fo1E:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
4 / 8 ILE E1048
VAL E1056
TRP E1059
ALA E1030
None
0.83A 6cduD-2fo1E:
undetectable
6cduE-2fo1E:
undetectable
6cduD-2fo1E:
22.58
6cduE-2fo1E:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
2fo1 LIN-12 PROTEIN
(Caenorhabditis
elegans)
4 / 7 ALA E1030
ILE E1048
VAL E1056
TRP E1059
None
0.80A 6cduF-2fo1E:
undetectable
6cduJ-2fo1E:
undetectable
6cduF-2fo1E:
22.58
6cduJ-2fo1E:
22.58