SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fp3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 2fp3 CASPASE NC
(Drosophila
melanogaster) 		5 / 11 PRO A 316
MET A 269
MET A 200
THR A 413
TYR A 371
 None
 1.45A 2uvnB-2fp3A:
undetectable		 2uvnB-2fp3A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 2fp3 CASPASE NC
(Drosophila
melanogaster) 		3 / 3 ARG A 212
ASP A 208
ASP A 205
 None
 0.94A 3jb3A-2fp3A:
1.5		 3jb3A-2fp3A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 2fp3 CASPASE NC
(Drosophila
melanogaster) 		3 / 3 ASN A 202
ALA A 216
ARG A 213
 None
 0.79A 3tj7C-2fp3A:
undetectable
3tj7D-2fp3A:
undetectable		 3tj7C-2fp3A:
19.94
3tj7D-2fp3A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2fp3 CASPASE NC
(Drosophila
melanogaster) 		4 / 5 TYR A 389
THR A 429
GLY A 185
LEU A 368
 None
 0.93A 5jlcA-2fp3A:
undetectable		 5jlcA-2fp3A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 2fp3 CASPASE NC
(Drosophila
melanogaster) 		5 / 12 VAL A 265
VAL A 267
ASP A 405
PHE A 443
PHE A 393
 None
 1.46A 6iblA-2fp3A:
undetectable		 6iblA-2fp3A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 2fp3 CASPASE NC
(Drosophila
melanogaster) 		5 / 12 VAL A 265
VAL A 267
ASP A 405
PHE A 443
PHE A 393
 None
 1.48A 6iblB-2fp3A:
undetectable		 6iblB-2fp3A:
20.45