SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fph'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2fph YLMH
(Streptococcus
pneumoniae) 		5 / 12 ILE X 155
ILE X 108
LEU X 149
VAL X 157
ILE X  94
 None
 0.94A 1oipA-2fphX:
undetectable		 1oipA-2fphX:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2fph YLMH
(Streptococcus
pneumoniae) 		5 / 8 LEU X 122
GLY X 117
LEU X 116
GLY X 148
ASP X 147
 None
 1.47A 2yfxA-2fphX:
undetectable		 2yfxA-2fphX:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2fph YLMH
(Streptococcus
pneumoniae) 		5 / 12 ILE X 155
ILE X 108
LEU X 149
VAL X 157
ILE X  94
 None
 0.91A 5mueA-2fphX:
undetectable		 5mueA-2fphX:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2fph YLMH
(Streptococcus
pneumoniae) 		5 / 12 ILE X 155
ILE X 108
LEU X 149
VAL X 157
ILE X  94
 None
 0.89A 5mugA-2fphX:
undetectable		 5mugA-2fphX:
21.65