SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL0_A_1UNA201_1 (PROTEASE)	2fq0	ACYL CARRIER PROTEIN (Plasmodium falciparum)	4 / 8	GLY A 34 ALA A 35 ASP A 36 ASP A 39	PNS A 137 ( 3.2A) None PNS A 137 (-2.3A) None	0.66A	3el0A-2fq0A: undetectable	3el0A-2fq0A: 25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3C_A_017A201_1 (HIV-1 PROTEASE)	2fq0	ACYL CARRIER PROTEIN (Plasmodium falciparum)	4 / 7	GLY A 34 ALA A 35 ASP A 36 ASP A 39	PNS A 137 ( 3.2A) None PNS A 137 (-2.3A) None	0.74A	3t3cA-2fq0A: undetectable	3t3cA-2fq0A: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EYR_B_RITB301_2 (HIV-1 PROTEASE)	2fq0	ACYL CARRIER PROTEIN (Plasmodium falciparum)	4 / 8	GLY A 34 ALA A 35 ASP A 36 ASP A 39	PNS A 137 ( 3.2A) None PNS A 137 (-2.3A) None	0.71A	4eyrB-2fq0A: undetectable	4eyrB-2fq0A: 25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LJD_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	2fq0	ACYL CARRIER PROTEIN (Plasmodium falciparum)	5 / 9	LEU A 40 ILE A 70 THR A 4 ILE A 23 GLN A 67	None	1.41A	5ljdA-2fq0A: undetectable	5ljdA-2fq0A: 19.71

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3EL0_A_1UNA201_1","PROTEASE","2fq0","ACYL CARRIER PROTEIN","Plasmodium falciparum",4,"GLY A  34;ALA A  35;ASP A  36;ASP A  39","PNS A 137 ( 3.2A);None;PNS A 137 (-2.3A);None","0.66A","3el0A-2fq0A:undetectable","3el0A-2fq0A:25.49"],["3T3C_A_017A201_1","HIV-1 PROTEASE","2fq0","ACYL CARRIER PROTEIN","Plasmodium falciparum",4,"GLY A  34;ALA A  35;ASP A  36;ASP A  39","PNS A 137 ( 3.2A);None;PNS A 137 (-2.3A);None","0.74A","3t3cA-2fq0A:undetectable","3t3cA-2fq0A:21.10"],["4EYR_B_RITB301_2","HIV-1 PROTEASE","2fq0","ACYL CARRIER PROTEIN","Plasmodium falciparum",4,"GLY A  34;ALA A  35;ASP A  36;ASP A  39","PNS A 137 ( 3.2A);None;PNS A 137 (-2.3A);None","0.71A","4eyrB-2fq0A:undetectable","4eyrB-2fq0A:25.49"],["5LJD_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","2fq0","ACYL CARRIER PROTEIN","Plasmodium falciparum",5,"LEU A  40;ILE A  70;THR A   4;ILE A  23;GLN A  67","None","1.41A","5ljdA-2fq0A:undetectable","5ljdA-2fq0A:19.71"]]