SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fqx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 11 LEU A  88
VAL A  58
PHE A  73
LEU A  70
PRO A  68
 None
 1.49A 1klmA-2fqxA:
undetectable		 1klmA-2fqxA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		4 / 7 LEU A 160
PHE A 161
GLY A 164
ILE A 322
 None
GMP  A 400 ( 4.8A)
None
None
 0.82A 2bdmA-2fqxA:
undetectable		 2bdmA-2fqxA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 ASN A 125
LEU A 130
VAL A 293
GLU A 289
LEU A 288
 None
 1.31A 2bxfB-2fqxA:
undetectable		 2bxfB-2fqxA:
20.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		12 / 12 ASP A  27
PHE A  36
ASN A  37
GLY A  85
ASP A 108
MET A 158
PHE A 161
PHE A 186
GLY A 212
VAL A 237
ASP A 238
LYS A 260
 GMP  A 400 (-2.9A)
GMP  A 400 (-3.8A)
GMP  A 400 (-3.3A)
GMP  A 400 ( 3.7A)
GMP  A 400 (-3.3A)
GMP  A 400 (-3.5A)
GMP  A 400 ( 4.8A)
GMP  A 400 (-3.4A)
GMP  A 400 (-3.3A)
GMP  A 400 (-4.7A)
GMP  A 400 (-2.9A)
GMP  A 400 (-2.8A)
 0.73A 2fqyA-2fqxA:
54.3		 2fqyA-2fqxA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 ALA A 292
GLY A 123
GLY A 287
ASP A 108
GLY A 127
 None
None
None
GMP  A 400 (-3.3A)
None
 0.88A 2qe6A-2fqxA:
undetectable		 2qe6A-2fqxA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_0
(N,N-DIMETHYLTRANSFER
ASE)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 GLY A 123
LEU A 130
SER A 128
ARG A 311
PHE A 286
 None
 1.27A 3bxoB-2fqxA:
3.2		 3bxoB-2fqxA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 GLY A 132
ILE A 235
ILE A 295
LEU A 137
VAL A 147
 None
 0.93A 3fpjA-2fqxA:
3.1		 3fpjA-2fqxA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 ASP A 238
GLY A 123
ALA A 262
ALA A 265
ASP A 263
 GMP  A 400 (-2.9A)
None
None
None
None
 1.12A 3keeA-2fqxA:
undetectable		 3keeA-2fqxA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 LEU A 130
SER A 128
PHE A 129
ILE A 317
LEU A 288
 None
 0.95A 3ko0A-2fqxA:
undetectable
3ko0B-2fqxA:
undetectable
3ko0C-2fqxA:
undetectable
3ko0D-2fqxA:
undetectable		 3ko0A-2fqxA:
13.92
3ko0B-2fqxA:
13.92
3ko0C-2fqxA:
13.92
3ko0D-2fqxA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		4 / 6 LEU A 130
SER A 128
PHE A 129
ILE A 317
 None
 0.68A 3ko0B-2fqxA:
undetectable		 3ko0B-2fqxA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 11 LEU A 288
LEU A 130
SER A 128
PHE A 129
ILE A 317
 None
 0.90A 3ko0A-2fqxA:
undetectable
3ko0B-2fqxA:
undetectable
3ko0I-2fqxA:
undetectable
3ko0J-2fqxA:
undetectable		 3ko0A-2fqxA:
13.92
3ko0B-2fqxA:
13.92
3ko0I-2fqxA:
13.92
3ko0J-2fqxA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 LEU A 130
SER A 128
PHE A 129
ILE A 317
LEU A 288
 None
 0.88A 3ko0K-2fqxA:
undetectable
3ko0L-2fqxA:
undetectable
3ko0S-2fqxA:
undetectable
3ko0T-2fqxA:
undetectable		 3ko0K-2fqxA:
13.92
3ko0L-2fqxA:
13.92
3ko0S-2fqxA:
13.92
3ko0T-2fqxA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 LEU A 288
LEU A 130
SER A 128
PHE A 129
ILE A 317
 None
 0.92A 3ko0K-2fqxA:
undetectable
3ko0L-2fqxA:
undetectable
3ko0M-2fqxA:
undetectable
3ko0N-2fqxA:
undetectable		 3ko0K-2fqxA:
13.92
3ko0L-2fqxA:
13.92
3ko0M-2fqxA:
13.92
3ko0N-2fqxA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 LEU A 130
SER A 128
PHE A 129
ILE A 317
LEU A 288
 None
 0.90A 3ko0M-2fqxA:
undetectable
3ko0N-2fqxA:
undetectable
3ko0O-2fqxA:
undetectable
3ko0P-2fqxA:
undetectable		 3ko0M-2fqxA:
13.92
3ko0N-2fqxA:
13.92
3ko0O-2fqxA:
13.92
3ko0P-2fqxA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 LEU A 288
LEU A 130
SER A 128
PHE A 129
ILE A 317
 None
 0.88A 3ko0M-2fqxA:
undetectable
3ko0N-2fqxA:
undetectable
3ko0O-2fqxA:
undetectable
3ko0P-2fqxA:
undetectable		 3ko0M-2fqxA:
13.92
3ko0N-2fqxA:
13.92
3ko0O-2fqxA:
13.92
3ko0P-2fqxA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		4 / 6 LEU A 130
SER A 128
PHE A 129
ILE A 317
 None
 0.73A 3ko0S-2fqxA:
undetectable		 3ko0S-2fqxA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 GLY A 280
ASP A 115
VAL A 111
LEU A  80
ILE A 269
 None
 1.03A 3ku1H-2fqxA:
2.5		 3ku1H-2fqxA:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		3 / 3 GLY A 132
ILE A 207
VAL A 206
 None
 0.44A 3nv6A-2fqxA:
undetectable		 3nv6A-2fqxA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 GLN A 209
GLY A 192
GLY A 215
ALA A 196
TYR A 200
 None
 0.97A 3sxjA-2fqxA:
undetectable		 3sxjA-2fqxA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 GLN A 209
GLY A 192
GLY A 215
ALA A 196
TYR A 200
 None
 0.98A 3sxjB-2fqxA:
undetectable		 3sxjB-2fqxA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		4 / 6 THR A 256
GLY A 236
ARG A 226
ILE A 219
 None
 0.98A 4acbC-2fqxA:
5.1		 4acbC-2fqxA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9W_A_VGHA1158_1
(7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 LEU A 105
MET A  24
VAL A  82
PHE A  36
GLN A  39
 None
None
None
GMP  A 400 (-3.8A)
None
 1.26A 4c9wA-2fqxA:
0.2		 4c9wA-2fqxA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 VAL A 306
ILE A 235
VAL A 206
LEU A 255
ALA A 136
 None
 1.11A 4o1zB-2fqxA:
undetectable		 4o1zB-2fqxA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		7 / 12 ASP A  27
SER A  35
ASN A  37
ASP A 108
PHE A 161
PHE A 186
GLY A 212
 GMP  A 400 (-2.9A)
GMP  A 400 ( 4.6A)
GMP  A 400 (-3.3A)
GMP  A 400 (-3.3A)
GMP  A 400 ( 4.8A)
GMP  A 400 (-3.4A)
GMP  A 400 (-3.3A)
 0.98A 4pevA-2fqxA:
39.8		 4pevA-2fqxA:
28.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 ASP A 263
VAL A 264
ASP A 238
PHE A 161
ASP A 108
 None
None
GMP  A 400 (-2.9A)
GMP  A 400 ( 4.8A)
GMP  A 400 (-3.3A)
 1.16A 4pevA-2fqxA:
39.8		 4pevA-2fqxA:
28.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		9 / 12 SER A  35
PHE A  36
ASN A  37
ASP A 108
PHE A 161
PHE A 186
GLY A 212
ASP A 238
LYS A 260
 GMP  A 400 ( 4.6A)
GMP  A 400 (-3.8A)
GMP  A 400 (-3.3A)
GMP  A 400 (-3.3A)
GMP  A 400 ( 4.8A)
GMP  A 400 (-3.4A)
GMP  A 400 (-3.3A)
GMP  A 400 (-2.9A)
GMP  A 400 (-2.8A)
 0.70A 4pevA-2fqxA:
39.8		 4pevA-2fqxA:
28.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		7 / 12 ASP A  27
SER A  35
ASN A  37
ASP A 108
PHE A 161
PHE A 186
GLY A 212
 GMP  A 400 (-2.9A)
GMP  A 400 ( 4.6A)
GMP  A 400 (-3.3A)
GMP  A 400 (-3.3A)
GMP  A 400 ( 4.8A)
GMP  A 400 (-3.4A)
GMP  A 400 (-3.3A)
 0.93A 4pevB-2fqxA:
39.7		 4pevB-2fqxA:
28.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 ASP A 263
VAL A 264
ASP A 238
PHE A 161
ASP A 108
 None
None
GMP  A 400 (-2.9A)
GMP  A 400 ( 4.8A)
GMP  A 400 (-3.3A)
 1.22A 4pevB-2fqxA:
39.7		 4pevB-2fqxA:
28.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		10 / 12 SER A  35
PHE A  36
ASN A  37
GLY A  85
ASP A 108
PHE A 161
PHE A 186
GLY A 212
ASP A 238
LYS A 260
 GMP  A 400 ( 4.6A)
GMP  A 400 (-3.8A)
GMP  A 400 (-3.3A)
GMP  A 400 ( 3.7A)
GMP  A 400 (-3.3A)
GMP  A 400 ( 4.8A)
GMP  A 400 (-3.4A)
GMP  A 400 (-3.3A)
GMP  A 400 (-2.9A)
GMP  A 400 (-2.8A)
 0.84A 4pevB-2fqxA:
39.7		 4pevB-2fqxA:
28.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		7 / 12 ASP A  27
SER A  35
ASN A  37
ASP A 108
PHE A 161
PHE A 186
GLY A 212
 GMP  A 400 (-2.9A)
GMP  A 400 ( 4.6A)
GMP  A 400 (-3.3A)
GMP  A 400 (-3.3A)
GMP  A 400 ( 4.8A)
GMP  A 400 (-3.4A)
GMP  A 400 (-3.3A)
 0.88A 4pevC-2fqxA:
39.5		 4pevC-2fqxA:
28.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 ASP A 263
VAL A 264
ASP A 238
PHE A 161
ASP A 108
 None
None
GMP  A 400 (-2.9A)
GMP  A 400 ( 4.8A)
GMP  A 400 (-3.3A)
 1.07A 4pevC-2fqxA:
39.5		 4pevC-2fqxA:
28.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		9 / 12 SER A  35
PHE A  36
ASN A  37
ASP A 108
PHE A 161
PHE A 186
GLY A 212
ASP A 238
LYS A 260
 GMP  A 400 ( 4.6A)
GMP  A 400 (-3.8A)
GMP  A 400 (-3.3A)
GMP  A 400 (-3.3A)
GMP  A 400 ( 4.8A)
GMP  A 400 (-3.4A)
GMP  A 400 (-3.3A)
GMP  A 400 (-2.9A)
GMP  A 400 (-2.8A)
 0.59A 4pevC-2fqxA:
39.5		 4pevC-2fqxA:
28.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 MET A 158
LEU A 160
GLY A 164
MET A 258
PHE A 149
 GMP  A 400 (-3.5A)
None
None
None
None
 1.46A 4udcA-2fqxA:
undetectable		 4udcA-2fqxA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		3 / 3 VAL A 133
LEU A 137
VAL A 172
 None
 0.63A 4wq4A-2fqxA:
undetectable		 4wq4A-2fqxA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		3 / 3 LEU A 255
LEU A 302
ARG A 261
 None
 0.58A 5hnzB-2fqxA:
1.9		 5hnzB-2fqxA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		4 / 7 GLY A 215
VAL A 254
ILE A 235
VAL A 234
 None
 0.76A 5ik1A-2fqxA:
undetectable		 5ik1A-2fqxA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		4 / 6 ILE A 235
GLY A 217
ASN A 216
ILE A 207
 None
 0.86A 5j4nB-2fqxA:
undetectable		 5j4nB-2fqxA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		3 / 3 VAL A 151
VAL A 210
GLN A 124
 None
GMP  A 400 (-4.0A)
GMP  A 400 ( 4.7A)
 0.68A 5qglA-2fqxA:
undetectable		 5qglA-2fqxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		3 / 3 VAL A 151
VAL A 210
GLN A 124
 None
GMP  A 400 (-4.0A)
GMP  A 400 ( 4.7A)
 0.69A 5qguA-2fqxA:
undetectable		 5qguA-2fqxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		3 / 3 VAL A 151
VAL A 210
GLN A 124
 None
GMP  A 400 (-4.0A)
GMP  A 400 ( 4.7A)
 0.70A 5qgvA-2fqxA:
undetectable		 5qgvA-2fqxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		3 / 3 VAL A 151
VAL A 210
GLN A 124
 None
GMP  A 400 (-4.0A)
GMP  A 400 ( 4.7A)
 0.70A 5qgwA-2fqxA:
undetectable		 5qgwA-2fqxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		3 / 3 VAL A 151
VAL A 210
GLN A 124
 None
GMP  A 400 (-4.0A)
GMP  A 400 ( 4.7A)
 0.70A 5qgxA-2fqxA:
undetectable		 5qgxA-2fqxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		3 / 3 VAL A 151
VAL A 210
GLN A 124
 None
GMP  A 400 (-4.0A)
GMP  A 400 ( 4.7A)
 0.70A 5qh1A-2fqxA:
undetectable		 5qh1A-2fqxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		3 / 3 VAL A 151
VAL A 210
GLN A 124
 None
GMP  A 400 (-4.0A)
GMP  A 400 ( 4.7A)
 0.70A 5qhcA-2fqxA:
undetectable		 5qhcA-2fqxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		3 / 3 VAL A 151
VAL A 210
GLN A 124
 None
GMP  A 400 (-4.0A)
GMP  A 400 ( 4.7A)
 0.68A 5qheA-2fqxA:
undetectable		 5qheA-2fqxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		3 / 3 VAL A 151
VAL A 210
GLN A 124
 None
GMP  A 400 (-4.0A)
GMP  A 400 ( 4.7A)
 0.72A 5qhfA-2fqxA:
undetectable		 5qhfA-2fqxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 12 LEU A  80
SER A  45
ALA A 262
ALA A 266
GLY A  43
 None
 1.18A 5tzoB-2fqxA:
undetectable		 5tzoB-2fqxA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 2fqx MEMBRANE LIPOPROTEIN
TMPC
(Treponema
pallidum) 		5 / 9 SER A  96
ALA A  91
VAL A 106
ALA A  83
VAL A 117
 None
 1.26A 6bklA-2fqxA:
undetectable
6bklB-2fqxA:
undetectable
6bklC-2fqxA:
undetectable
6bklD-2fqxA:
undetectable		 6bklA-2fqxA:
7.51
6bklB-2fqxA:
7.51
6bklC-2fqxA:
7.51
6bklD-2fqxA:
7.51