SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		3 / 3 SER A 214
GLU A 215
GLU A 216
 None
 0.61A 1eqbD-2fqzA:
undetectable		 1eqbD-2fqzA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		3 / 3 SER A 214
GLU A 215
GLU A 216
 None
 0.61A 1eqbB-2fqzA:
undetectable		 1eqbB-2fqzA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		3 / 3 GLU A 123
LYS A  30
VAL A  28
 None
 0.92A 1l2iA-2fqzA:
undetectable		 1l2iA-2fqzA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		3 / 3 ILE A 127
ILE A  53
THR A  31
 None
 0.60A 1rg7A-2fqzA:
undetectable		 1rg7A-2fqzA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		5 / 9 TYR A 295
LEU A 161
ALA A 255
LEU A 252
ALA A 135
 None
 1.20A 2vcvD-2fqzA:
1.3		 2vcvD-2fqzA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		4 / 6 LEU A 161
ALA A 255
LEU A 252
ALA A 135
 None
 0.99A 2vcvK-2fqzA:
1.4		 2vcvK-2fqzA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		4 / 7 SER A 278
ILE A 145
PRO A 164
GLY A 165
 None
 0.91A 2y7kA-2fqzA:
undetectable		 2y7kA-2fqzA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		4 / 5 TYR A 205
MET A 177
THR A 176
LEU A 258
 None
 1.46A 3ag1J-2fqzA:
undetectable		 3ag1J-2fqzA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		3 / 3 ASP A 210
SER A 212
ARG A 186
 None
 1.00A 3loqA-2fqzA:
undetectable		 3loqA-2fqzA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		4 / 7 ILE A 275
GLN A 168
GLY A 165
SER A 278
 None
 0.87A 4a3uB-2fqzA:
undetectable		 4a3uB-2fqzA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		5 / 12 LEU A 130
PHE A  25
GLN A 282
ALA A 144
ASP A 288
 None
 1.27A 4j7xA-2fqzA:
undetectable		 4j7xA-2fqzA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		4 / 8 GLU A 129
PHE A 124
GLY A 121
THR A 230
 None
 0.93A 5flcB-2fqzA:
undetectable		 5flcB-2fqzA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		4 / 8 GLU A 129
PHE A 124
GLY A 121
THR A 230
 None
 0.94A 5flcF-2fqzA:
undetectable		 5flcF-2fqzA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		5 / 12 GLY A  36
SER A 126
ILE A 127
TYR A  52
MET A  56
 None
 1.43A 5igwA-2fqzA:
undetectable		 5igwA-2fqzA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		4 / 5 TYR A 205
MET A 177
THR A 176
LEU A 258
 None
 1.41A 5w97J-2fqzA:
undetectable		 5w97J-2fqzA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		4 / 5 TYR A 205
MET A 177
THR A 176
LEU A 258
 None
 1.37A 5x19J-2fqzA:
undetectable		 5x19J-2fqzA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		4 / 5 TYR A 205
MET A 177
THR A 176
LEU A 258
 None
 1.43A 5x1bJ-2fqzA:
undetectable		 5x1bJ-2fqzA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		4 / 5 TYR A 205
MET A 177
THR A 176
LEU A 258
 None
 1.39A 5x1bW-2fqzA:
undetectable		 5x1bW-2fqzA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		4 / 5 TYR A 205
MET A 177
THR A 176
LEU A 258
 None
 1.36A 5x1fW-2fqzA:
undetectable		 5x1fW-2fqzA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		3 / 3 MET A 204
ASP A 160
ARG A 188
 None
 0.82A 5z6jA-2fqzA:
undetectable		 5z6jA-2fqzA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2fqz R.ECL18KI
(Enterobacter
cloacae) 		3 / 3 MET A 204
ASP A 160
ARG A 188
 None
 1.02A 5z6kA-2fqzA:
undetectable		 5z6kA-2fqzA:
18.87