SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2frg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_B_CTXB2_2 (CES1 PROTEIN)	2frg	TREM-LIKE TRANSCRIPT-1 (Homo sapiens)	4 / 4	LEU P 87 PRO P 23 ILE P 114 LEU P 115	None	1.11A	1ya4B-2frgP: undetectable	1ya4B-2frgP: 11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCD_A_RAPA138_1 (OUTER MEMBRANE PROTEIN MIP)	2frg	TREM-LIKE TRANSCRIPT-1 (Homo sapiens)	5 / 11	TYR P 102 ASP P 98 GLN P 88 VAL P 36 ILE P 34	None	1.46A	2vcdA-2frgP: undetectable	2vcdA-2frgP: 22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X20_D_LOCD502_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	2frg	TREM-LIKE TRANSCRIPT-1 (Homo sapiens)	3 / 3	SER P 64 ALA P 66 VAL P 67	None	0.38A	4x20C-2frgP: undetectable	4x20C-2frgP: 14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F8Y_A_X6XA202_1 (GALNAC/GAL-SPECIFIC LECTIN)	2frg	TREM-LIKE TRANSCRIPT-1 (Homo sapiens)	4 / 8	GLY P 84 GLY P 85 VAL P 67 ASP P 44	None	0.77A	5f8yA-2frgP: undetectable	5f8yA-2frgP: 20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F8Y_B_X6XB201_1 (GALNAC/GAL-SPECIFIC LECTIN)	2frg	TREM-LIKE TRANSCRIPT-1 (Homo sapiens)	4 / 8	GLY P 84 GLY P 85 VAL P 67 ASP P 44	None	0.78A	5f8yB-2frgP: undetectable	5f8yB-2frgP: 20.26

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YA4_B_CTXB2_2","CES1 PROTEIN","2frg","TREM-LIKE TRANSCRIPT-1","Homo sapiens",4,"LEU P  87;PRO P  23;ILE P 114;LEU P 115","None","1.11A","1ya4B-2frgP:undetectable","1ya4B-2frgP:11.28"],["2VCD_A_RAPA138_1","OUTER MEMBRANE PROTEIN MIP","2frg","TREM-LIKE TRANSCRIPT-1","Homo sapiens",5,"TYR P 102;ASP P  98;GLN P  88;VAL P  36;ILE P  34","None","1.46A","2vcdA-2frgP:undetectable","2vcdA-2frgP:22.86"],["4X20_D_LOCD502_1","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","2frg","TREM-LIKE TRANSCRIPT-1","Homo sapiens",3,"SER P  64;ALA P  66;VAL P  67","None","0.38A","4x20C-2frgP:undetectable","4x20C-2frgP:14.44"],["5F8Y_A_X6XA202_1","GALNAC\/GAL-SPECIFIC LECTIN","2frg","TREM-LIKE TRANSCRIPT-1","Homo sapiens",4,"GLY P  84;GLY P  85;VAL P  67;ASP P  44","None","0.77A","5f8yA-2frgP:undetectable","5f8yA-2frgP:20.26"],["5F8Y_B_X6XB201_1","GALNAC\/GAL-SPECIFIC LECTIN","2frg","TREM-LIKE TRANSCRIPT-1","Homo sapiens",4,"GLY P  84;GLY P  85;VAL P  67;ASP P  44","None","0.78A","5f8yB-2frgP:undetectable","5f8yB-2frgP:20.26"]]