SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fsq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 2fsq ATU0111 PROTEIN
(Agrobacterium
fabrum) 		4 / 6 ILE A 184
PRO A  77
SER A  80
MET A 227
 None
 1.46A 2qd3B-2fsqA:
undetectable		 2qd3B-2fsqA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2fsq ATU0111 PROTEIN
(Agrobacterium
fabrum) 		5 / 12 MET A 131
PHE A 177
THR A 134
GLY A 140
ARG A 137
 None
 1.46A 3aodC-2fsqA:
undetectable		 3aodC-2fsqA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 2fsq ATU0111 PROTEIN
(Agrobacterium
fabrum) 		4 / 8 GLY A  88
THR A 113
TYR A 116
ASN A  41
 None
 1.01A 4m5mA-2fsqA:
1.1		 4m5mA-2fsqA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 2fsq ATU0111 PROTEIN
(Agrobacterium
fabrum) 		5 / 12 GLU A  34
GLY A  33
LEU A  73
SER A  71
SER A 182
 None
 1.11A 5dpdA-2fsqA:
undetectable		 5dpdA-2fsqA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA407_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 2fsq ATU0111 PROTEIN
(Agrobacterium
fabrum) 		4 / 5 ASP A 110
THR A 113
ARG A 117
GLU A 223
 None
 0.90A 5k9dA-2fsqA:
0.0		 5k9dA-2fsqA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 2fsq ATU0111 PROTEIN
(Agrobacterium
fabrum) 		4 / 6 ARG A  28
GLY A  26
GLU A  38
SER A  92
 None
 0.82A 5ny7A-2fsqA:
undetectable		 5ny7A-2fsqA:
21.67