SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ft0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 2ft0 TDP-FUCOSAMINE
ACETYLTRANSFERASE
(Escherichia
coli) 		3 / 3 TRP A 184
ALA A  85
VAL A  87
 None
 0.85A 1bdwA-2ft0A:
undetectable
1bdwB-2ft0A:
undetectable		 1bdwA-2ft0A:
5.11
1bdwB-2ft0A:
5.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2ft0 TDP-FUCOSAMINE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 11 ILE A 141
CYH A 139
LEU A 155
MET A 178
THR A 180
 None
 1.19A 1pkvA-2ft0A:
undetectable
1pkvB-2ft0A:
undetectable		 1pkvA-2ft0A:
19.15
1pkvB-2ft0A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 2ft0 TDP-FUCOSAMINE
ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 6 LYS A 206
GLN A 210
GLY A 212
LEU A 182
 None
 0.95A 3bjwE-2ft0A:
undetectable		 3bjwE-2ft0A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 2ft0 TDP-FUCOSAMINE
ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 8 ALA A 100
GLY A 151
VAL A 131
ILE A 127
 None
 0.71A 4ll3A-2ft0A:
undetectable		 4ll3A-2ft0A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 2ft0 TDP-FUCOSAMINE
ACETYLTRANSFERASE
(Escherichia
coli) 		3 / 3 LEU A 155
ASP A 136
ILE A 141
 None
 0.69A 4xi3D-2ft0A:
undetectable		 4xi3D-2ft0A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 2ft0 TDP-FUCOSAMINE
ACETYLTRANSFERASE
(Escherichia
coli) 		3 / 3 VAL A  44
SER A  21
TRP A  41
 None
 1.04A 5jwaA-2ft0A:
undetectable		 5jwaA-2ft0A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 2ft0 TDP-FUCOSAMINE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 THR A 191
LEU A 193
LEU A  75
ASN A  78
LEU A 182
 None
 0.98A 5nfjA-2ft0A:
undetectable		 5nfjA-2ft0A:
20.25