SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ft7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  46
CYH A 112
HIS A 115
MET A 117
 CU1  A 200 (-3.0A)
CU1  A 200 (-2.0A)
CU1  A 200 (-3.3A)
CU1  A 200 (-2.5A)
 0.40A 1oe1A-2ft7A:
3.6		 1oe1A-2ft7A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		5 / 5 HIS A  46
CYH A 112
PRO A 114
HIS A 115
MET A 117
 CU1  A 200 (-3.0A)
CU1  A 200 (-2.0A)
CU1  A 200 ( 4.5A)
CU1  A 200 (-3.3A)
CU1  A 200 (-2.5A)
 0.82A 1oe2A-2ft7A:
7.2		 1oe2A-2ft7A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  46
CYH A 112
HIS A 115
MET A 117
 CU1  A 200 (-3.0A)
CU1  A 200 (-2.0A)
CU1  A 200 (-3.3A)
CU1  A 200 (-2.5A)
 0.42A 1oe3A-2ft7A:
3.6		 1oe3A-2ft7A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  46
CYH A 112
HIS A 115
MET A 117
 CU1  A 200 (-3.0A)
CU1  A 200 (-2.0A)
CU1  A 200 (-3.3A)
CU1  A 200 (-2.5A)
 0.42A 2fqdA-2ft7A:
2.6		 2fqdA-2ft7A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  46
CYH A 112
HIS A 115
MET A 117
 CU1  A 200 (-3.0A)
CU1  A 200 (-2.0A)
CU1  A 200 (-3.3A)
CU1  A 200 (-2.5A)
 0.40A 2fqeA-2ft7A:
2.6		 2fqeA-2ft7A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  46
CYH A 112
HIS A 115
MET A 117
 CU1  A 200 (-3.0A)
CU1  A 200 (-2.0A)
CU1  A 200 (-3.3A)
CU1  A 200 (-2.5A)
 0.39A 2fqfA-2ft7A:
undetectable		 2fqfA-2ft7A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  46
CYH A 112
HIS A 115
MET A 117
 CU1  A 200 (-3.0A)
CU1  A 200 (-2.0A)
CU1  A 200 (-3.3A)
CU1  A 200 (-2.5A)
 0.41A 2fqgA-2ft7A:
undetectable		 2fqgA-2ft7A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  46
CYH A 112
HIS A 115
MET A 117
 CU1  A 200 (-3.0A)
CU1  A 200 (-2.0A)
CU1  A 200 (-3.3A)
CU1  A 200 (-2.5A)
 0.38A 2xxgA-2ft7A:
6.2		 2xxgA-2ft7A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		5 / 5 HIS A  46
CYH A 112
PRO A 114
HIS A 115
MET A 117
 CU1  A 200 (-3.0A)
CU1  A 200 (-2.0A)
CU1  A 200 ( 4.5A)
CU1  A 200 (-3.3A)
CU1  A 200 (-2.5A)
 0.86A 2xxgC-2ft7A:
7.2		 2xxgC-2ft7A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		3 / 3 GLY A  67
PRO A 114
LEU A  86
 None
CU1  A 200 ( 4.5A)
None
 0.45A 3hcpB-2ft7A:
undetectable		 3hcpB-2ft7A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  46
CYH A 112
HIS A 115
MET A 117
 CU1  A 200 (-3.0A)
CU1  A 200 (-2.0A)
CU1  A 200 (-3.3A)
CU1  A 200 (-2.5A)
 0.38A 4ef3A-2ft7A:
2.7		 4ef3A-2ft7A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  87
THR A  84
SER A   4
PHE A  15
GLY A   9
 None
 0.87A 4rzvA-2ft7A:
undetectable		 4rzvA-2ft7A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 2ft7 AZURIN
(Pseudomonas
aeruginosa) 		4 / 6 ASN A  47
TYR A  72
VAL A  49
VAL A  60
 None
 1.42A 6f32B-2ft7A:
undetectable		 6f32B-2ft7A:
13.04