SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fuk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 5 ARG A  78
ALA A  84
ASP A  96
GLY A  17
 None
 1.02A 1e7bA-2fukA:
0.5		 1e7bA-2fukA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		5 / 12 ASP A  27
GLY A 117
SER A 139
ALA A  62
ALA A  61
 None
 1.24A 1nw5A-2fukA:
2.1		 1nw5A-2fukA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		5 / 12 ASP A  27
GLY A 117
VAL A 124
ALA A  62
ALA A  61
 None
 1.31A 1nw5A-2fukA:
2.1		 1nw5A-2fukA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 4 ILE A  41
ASP A  95
LEU A  22
ARG A 105
 None
 1.46A 2a7qA-2fukA:
3.5		 2a7qA-2fukA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		5 / 12 ALA A 141
ILE A 168
ILE A 138
SER A 139
ALA A  61
 None
 1.13A 2ejtA-2fukA:
undetectable		 2ejtA-2fukA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 SER A  47
SER A  79
PHE A  87
ASP A  91
 None
 1.11A 2obvA-2fukA:
undetectable		 2obvA-2fukA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 SER A  47
SER A  79
PHE A  87
ASP A  91
 None
 1.16A 2p02A-2fukA:
undetectable		 2p02A-2fukA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		5 / 12 ALA A 141
ILE A 168
ILE A 138
SER A 139
ALA A  61
 None
 1.17A 3axtA-2fukA:
undetectable		 3axtA-2fukA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		5 / 11 ALA A  61
ILE A 140
GLY A 117
LEU A 208
LEU A 159
 None
 0.98A 3kw2B-2fukA:
undetectable		 3kw2B-2fukA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		5 / 12 ILE A 140
GLY A 121
ALA A 122
SER A 125
LEU A 126
 None
 1.01A 3n8xA-2fukA:
undetectable		 3n8xA-2fukA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 GLY A 206
ALA A 207
PRO A 191
THR A 193
 None
 0.86A 4eyrB-2fukA:
undetectable		 4eyrB-2fukA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 PRO A  18
SER A  79
SER A  47
ASP A  95
 None
 1.02A 4kttA-2fukA:
undetectable		 4kttA-2fukA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 SER A  47
SER A  79
PHE A  87
ASP A  91
 None
 1.12A 4kttA-2fukA:
undetectable		 4kttA-2fukA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 PRO A  18
SER A  79
SER A  47
ASP A  95
 None
 0.97A 4kttC-2fukA:
undetectable		 4kttC-2fukA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 SER A  47
SER A  79
PHE A  87
ASP A  91
 None
 1.12A 4kttC-2fukA:
undetectable		 4kttC-2fukA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 PRO A  18
SER A  79
SER A  47
ASP A  95
 None
 1.02A 4ndnA-2fukA:
undetectable		 4ndnA-2fukA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 SER A  47
SER A  79
PHE A  87
ASP A  91
 None
 1.18A 4ndnA-2fukA:
undetectable		 4ndnA-2fukA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		3 / 3 SER A  10
ALA A  25
VAL A  24
 None
 0.62A 4o2bC-2fukA:
4.9		 4o2bC-2fukA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		5 / 9 PRO A  29
VAL A  38
ALA A  25
VAL A  42
ALA A  40
 None
 1.25A 4oqrA-2fukA:
undetectable		 4oqrA-2fukA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		5 / 10 LEU A 132
CYH A  43
LEU A  97
ALA A 101
LEU A 113
 None
 1.19A 4p65A-2fukA:
undetectable
4p65B-2fukA:
undetectable
4p65F-2fukA:
undetectable
4p65H-2fukA:
undetectable		 4p65A-2fukA:
7.45
4p65B-2fukA:
7.31
4p65F-2fukA:
7.31
4p65H-2fukA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		3 / 3 SER A  10
ALA A  25
VAL A  24
 None
 0.55A 4x20C-2fukA:
undetectable		 4x20C-2fukA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 SER A  47
SER A  79
PHE A  87
ASP A  91
 None
 1.16A 5a1iA-2fukA:
undetectable		 5a1iA-2fukA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		5 / 12 LEU A  65
GLY A 117
ALA A  61
PRO A 142
PHE A 120
 None
 1.16A 5x6yC-2fukA:
2.0		 5x6yC-2fukA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 PRO A  18
SER A  79
SER A  47
ASP A  95
 None
 1.03A 6fbnB-2fukA:
undetectable		 6fbnB-2fukA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 SER A  47
SER A  79
PHE A  87
ASP A  91
 None
 1.18A 6fbnB-2fukA:
undetectable		 6fbnB-2fukA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 SER A  47
SER A  79
PHE A  87
ASP A  91
 None
 1.14A 6fboA-2fukA:
undetectable		 6fboA-2fukA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 PRO A  18
SER A  79
SER A  47
ASP A  95
 None
 0.97A 6fcbA-2fukA:
undetectable		 6fcbA-2fukA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 SER A  47
SER A  79
PHE A  87
ASP A  91
 None
 1.13A 6fcbA-2fukA:
undetectable		 6fcbA-2fukA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 SER A  47
SER A  79
PHE A  87
ASP A  91
 None
 1.15A 6fcdA-2fukA:
undetectable		 6fcdA-2fukA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 2fuk XC6422 PROTEIN
(Xanthomonas
campestris) 		4 / 8 TYR A 123
PHE A 120
PHE A  87
HIS A  89
 None
 1.09A 6huoC-2fukA:
undetectable
6huoD-2fukA:
undetectable		 6huoC-2fukA:
17.06
6huoD-2fukA:
16.36