SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ful'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 2ful EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5
(Saccharomyces
cerevisiae) 		3 / 3 ASN A 352
ALA A 305
ASN A 308
 None
 0.81A 1n4fA-2fulA:
undetectable		 1n4fA-2fulA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2ful EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 328
ALA A 385
PHE A 388
LEU A 392
MET A 362
 None
 1.10A 1uduA-2fulA:
undetectable		 1uduA-2fulA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2ful EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 328
ALA A 385
PHE A 388
LEU A 392
MET A 362
 None
 1.09A 1uduB-2fulA:
undetectable		 1uduB-2fulA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 2ful EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5
(Saccharomyces
cerevisiae) 		3 / 3 GLY A 326
GLU A 329
ASN A 323
 None
 0.66A 1zq9A-2fulA:
undetectable		 1zq9A-2fulA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 2ful EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 314
PHE A 311
ALA A 276
VAL A 290
LEU A 295
 None
 1.14A 3s79A-2fulA:
undetectable		 3s79A-2fulA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 2ful EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5
(Saccharomyces
cerevisiae) 		5 / 8 LYS A 386
ALA A 385
LEU A 343
LEU A 347
GLU A 329
 None
 1.42A 4po0A-2fulA:
undetectable		 4po0A-2fulA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 2ful EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 314
PHE A 311
ALA A 276
VAL A 290
LEU A 295
 None
 1.14A 5jkvA-2fulA:
undetectable		 5jkvA-2fulA:
16.57