SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fup'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 2fup HYPOTHETICAL PROTEIN
PA3352
(Pseudomonas
aeruginosa) 		4 / 5 GLU A  13
LEU A   7
LEU A  10
LEU A   8
 None
 1.10A 1np1A-2fupA:
undetectable		 1np1A-2fupA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 2fup HYPOTHETICAL PROTEIN
PA3352
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 126
SER A 124
LEU A 109
LEU A  21
 None
 1.07A 4n09A-2fupA:
undetectable		 4n09A-2fupA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 2fup HYPOTHETICAL PROTEIN
PA3352
(Pseudomonas
aeruginosa) 		4 / 8 LEU A  22
ASN A 108
ALA A 107
GLU A 102
 None
 0.92A 4zbqA-2fupA:
undetectable		 4zbqA-2fupA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 2fup HYPOTHETICAL PROTEIN
PA3352
(Pseudomonas
aeruginosa) 		4 / 4 LEU A  91
LEU A  77
GLY A  76
GLU A  75
 None
MPD  A 157 ( 4.4A)
None
None
 1.27A 5hhjA-2fupA:
undetectable		 5hhjA-2fupA:
19.74