SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2fur HYPOTHETICAL PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 ALA A  26
LEU A  28
ASN A  31
ALA A 104
ILE A 106
 None
 1.03A 3ut5B-2furA:
undetectable		 3ut5B-2furA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 2fur HYPOTHETICAL PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 ALA A  26
LEU A  28
ASN A  31
ALA A 104
ILE A 106
 None
 1.02A 3ut5D-2furA:
undetectable		 3ut5D-2furA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 2fur HYPOTHETICAL PROTEIN
(Thermoplasma
acidophilum) 		4 / 4 LEU A  72
ILE A  47
GLY A  70
PHE A  38
 None
 1.11A 4dc3A-2furA:
undetectable		 4dc3A-2furA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2fur HYPOTHETICAL PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 ALA A  26
LEU A  28
ASN A  31
ALA A 104
ILE A 106
 None
 1.13A 4x1yB-2furA:
undetectable		 4x1yB-2furA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 2fur HYPOTHETICAL PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 ALA A  26
LEU A  28
ASN A  31
ALA A 104
ILE A 106
 None
 1.09A 5itzB-2furA:
undetectable		 5itzB-2furA:
18.91