SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fus'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 2fus FUMARASE C
(Escherichia
coli) 		4 / 6 PHE A 258
ALA A 251
LEU A 250
ILE A 253
 None
 1.06A 1sbrA-2fusA:
undetectable
1sbrB-2fusA:
undetectable		 1sbrA-2fusA:
18.59
1sbrB-2fusA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_2
(NEURAMINIDASE)		 2fus FUMARASE C
(Escherichia
coli) 		4 / 4 ASP A 294
TRP A 297
ILE A 306
ARG A 186
 None
 1.39A 2htqA-2fusA:
undetectable		 2htqA-2fusA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 2fus FUMARASE C
(Escherichia
coli) 		5 / 12 GLY A 203
CYH A 337
LEU A 376
ALA A 206
VAL A 205
 None
 1.07A 3av6A-2fusA:
undetectable		 3av6A-2fusA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2fus FUMARASE C
(Escherichia
coli) 		4 / 4 LEU A  91
PRO A  90
LEU A  30
ARG A  28
 None
 1.16A 3hcoB-2fusA:
undetectable		 3hcoB-2fusA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 2fus FUMARASE C
(Escherichia
coli) 		5 / 12 GLY A 229
GLY A 235
ASN A 237
ALA A 261
LEU A 268
 None
 1.03A 3mteB-2fusA:
undetectable		 3mteB-2fusA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 2fus FUMARASE C
(Escherichia
coli) 		4 / 8 ALA A  77
LEU A 110
ALA A  55
ALA A  56
 None
 0.63A 3r9tA-2fusA:
undetectable		 3r9tA-2fusA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 2fus FUMARASE C
(Escherichia
coli) 		5 / 12 ILE A 215
GLN A 163
LEU A 164
LEU A 284
ILE A 291
 None
 1.14A 4g1bD-2fusA:
undetectable		 4g1bD-2fusA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2fus FUMARASE C
(Escherichia
coli) 		4 / 5 MET A 148
LEU A 274
PRO A  41
SER A  43
 None
 1.40A 4kmmB-2fusA:
undetectable		 4kmmB-2fusA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 2fus FUMARASE C
(Escherichia
coli) 		5 / 11 GLY A 233
GLY A 229
GLY A 228
ALA A 231
GLN A 138
 None
 1.17A 4l8fB-2fusA:
undetectable		 4l8fB-2fusA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 2fus FUMARASE C
(Escherichia
coli) 		5 / 12 SER A  43
ILE A 366
LEU A 274
ALA A 155
LEU A 156
 None
 1.34A 5zwrB-2fusA:
undetectable		 5zwrB-2fusA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 2fus FUMARASE C
(Escherichia
coli) 		5 / 10 TRP A 204
MET A 289
ALA A 292
THR A 168
PHE A 383
 None
 1.47A 6hu9C-2fusA:
4.3		 6hu9C-2fusA:
20.77