SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fuv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		5 / 8 ARG A 336
LEU A 332
ALA A 395
GLY A 411
ILE A 412
 None
 1.50A 1d4sB-2fuvA:
undetectable		 1d4sB-2fuvA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		5 / 12 PHE A 211
TYR A 307
ILE A 312
TYR A 324
LEU A 215
 None
 1.27A 1fm4A-2fuvA:
3.3		 1fm4A-2fuvA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_B_SAMB501_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		5 / 12 ASP A  86
ILE A 143
PHE A 117
GLY A  84
THR A 120
 None
 0.98A 1g60B-2fuvA:
undetectable		 1g60B-2fuvA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		3 / 3 ALA A 484
VAL A 369
TRP A 375
 None
 0.89A 1jnoA-2fuvA:
undetectable		 1jnoA-2fuvA:
5.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		3 / 3 ALA A 484
VAL A 369
TRP A 375
 None
 0.89A 1jnoB-2fuvA:
undetectable		 1jnoB-2fuvA:
5.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		3 / 3 ALA A 484
VAL A 369
TRP A 375
 None
 0.93A 1jo3A-2fuvA:
undetectable		 1jo3A-2fuvA:
5.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		3 / 3 ALA A 484
VAL A 369
TRP A 375
 None
 0.93A 1jo3B-2fuvA:
undetectable		 1jo3B-2fuvA:
5.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		3 / 3 ALA A 484
VAL A 369
TRP A 375
 None
 0.91A 1ng8A-2fuvA:
undetectable		 1ng8A-2fuvA:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		3 / 3 ALA A 484
VAL A 369
TRP A 375
 None
 0.91A 1ng8B-2fuvA:
undetectable		 1ng8B-2fuvA:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		3 / 3 HIS A 310
ASP A 306
ASN A 148
 None
MG  A 901 (-2.1A)
None
 0.72A 1wg8B-2fuvA:
undetectable		 1wg8B-2fuvA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		5 / 11 ASP A 260
MET A 287
GLY A 238
THR A  87
VAL A 262
 None
 1.41A 2uvnB-2fuvA:
undetectable		 2uvnB-2fuvA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		5 / 10 PHE A 373
ILE A 312
PHE A 387
LEU A 398
GLY A 389
 None
 1.11A 2v0mA-2fuvA:
undetectable		 2v0mA-2fuvA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		4 / 8 ASN A 131
ILE A 127
ASP A 139
ARG A  72
 None
 0.96A 2v57A-2fuvA:
undetectable		 2v57A-2fuvA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		4 / 8 ASN A 131
ILE A 127
ASP A 139
ARG A  72
 None
 0.96A 2v57C-2fuvA:
undetectable		 2v57C-2fuvA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		3 / 3 PHE A 376
SER A 351
LEU A 349
 None
 0.66A 2w1bA-2fuvA:
undetectable		 2w1bA-2fuvA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		3 / 3 SER A  97
HIS A  88
ASP A 306
 None
None
MG  A 901 (-2.1A)
 0.77A 2wa2B-2fuvA:
undetectable		 2wa2B-2fuvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		4 / 7 ARG A 190
ASN A 105
GLY A 106
VAL A 109
 None
 0.84A 2y05A-2fuvA:
undetectable
2y05B-2fuvA:
3.5		 2y05A-2fuvA:
21.03
2y05B-2fuvA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		5 / 12 ILE A  68
ALA A  67
ASN A 168
PHE A  42
ALA A 177
 None
 1.02A 3dzyA-2fuvA:
undetectable		 3dzyA-2fuvA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		3 / 3 ASP A 306
SER A 146
ARG A 309
 MG  A 901 (-2.1A)
MG  A 901 (-2.1A)
None
 0.86A 3loqA-2fuvA:
2.3		 3loqA-2fuvA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		5 / 10 VAL A 367
VAL A 369
TRP A 375
GLY A 346
GLY A 388
 None
 0.98A 3ls4H-2fuvA:
undetectable		 3ls4H-2fuvA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		4 / 5 LEU A 325
ILE A 312
ALA A 328
MET A 319
 None
 1.09A 4dc3B-2fuvA:
undetectable		 4dc3B-2fuvA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		4 / 4 ASN A 161
GLY A 163
ASP A 175
ASP A 166
 None
 1.17A 4n49A-2fuvA:
undetectable		 4n49A-2fuvA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		4 / 6 ASP A 308
ASP A 306
ASN A 148
ARG A  48
 MG  A 901 (-2.7A)
MG  A 901 (-2.1A)
None
None
 1.06A 4ntxA-2fuvA:
undetectable
4ntxC-2fuvA:
undetectable		 4ntxA-2fuvA:
21.47
4ntxC-2fuvA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		3 / 3 ARG A 447
GLU A 390
TYR A 518
 None
 0.73A 4r29D-2fuvA:
undetectable		 4r29D-2fuvA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		4 / 4 ILE A 127
ASN A 158
ILE A 141
VAL A  83
 None
 1.24A 4uy87-2fuvA:
undetectable		 4uy87-2fuvA:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		4 / 5 THR A  87
GLY A 237
HIS A 147
ASP A  86
 None
 1.20A 5c0oH-2fuvA:
undetectable		 5c0oH-2fuvA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		5 / 12 VAL A 359
LEU A 362
ILE A 413
MET A 414
ILE A 329
 None
 1.10A 5hbsA-2fuvA:
undetectable		 5hbsA-2fuvA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		5 / 12 VAL A 359
LEU A 362
MET A 414
ILE A 329
LEU A 380
 None
 1.18A 5hbsA-2fuvA:
undetectable		 5hbsA-2fuvA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		4 / 8 ILE A 412
GLY A 411
PHE A 266
ASP A 306
 None
None
None
MG  A 901 (-2.1A)
 0.89A 5hieD-2fuvA:
undetectable		 5hieD-2fuvA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		4 / 7 GLY A 494
VAL A 542
ILE A 538
VAL A 539
 None
 0.79A 5ik1A-2fuvA:
undetectable		 5ik1A-2fuvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		5 / 11 ALA A 328
ALA A 326
GLY A 388
GLY A 389
ALA A 395
 None
 1.02A 5lf3K-2fuvA:
undetectable
5lf3L-2fuvA:
undetectable		 5lf3K-2fuvA:
18.97
5lf3L-2fuvA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		5 / 11 ALA A 328
ALA A 326
GLY A 388
GLY A 389
ALA A 395
 None
 1.03A 5lf3Y-2fuvA:
undetectable
5lf3Z-2fuvA:
undetectable		 5lf3Y-2fuvA:
18.97
5lf3Z-2fuvA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		4 / 6 PHE A  42
ILE A 155
ASP A 152
GLY A  49
 None
 0.98A 5x5qE-2fuvA:
undetectable		 5x5qE-2fuvA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 2fuv PHOSPHOGLUCOMUTASE
(Salmonella
enterica) 		4 / 6 ASP A 306
ASN A 158
SER A 406
PHE A 211
 MG  A 901 (-2.1A)
None
None
None
 1.27A 6ekuA-2fuvA:
undetectable		 6ekuA-2fuvA:
22.11