SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fv2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ALA A  85
GLN A  82
LEU A 130
ALA A 129
LEU A  51
 None
 0.72A 1fm6A-2fv2A:
undetectable		 1fm6A-2fv2A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ALA A  85
GLN A  82
LEU A 130
ALA A 129
LEU A  51
 None
 0.82A 1xdkA-2fv2A:
undetectable		 1xdkA-2fv2A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ALA A  85
GLN A  82
LEU A 130
ALA A 129
LEU A  51
 None
 0.82A 1xdkE-2fv2A:
undetectable		 1xdkE-2fv2A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ALA A  85
GLN A  82
LEU A 130
ALA A 129
LEU A  51
 None
 0.69A 1xiuA-2fv2A:
undetectable		 1xiuA-2fv2A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ASN A  76
ALA A  79
SER A 123
LEU A 103
LEU A 119
 None
 1.17A 1ya3B-2fv2A:
undetectable		 1ya3B-2fv2A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ALA A  85
GLN A  82
LEU A 130
ALA A 129
LEU A  51
 None
 0.73A 3dzyA-2fv2A:
undetectable		 3dzyA-2fv2A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ALA A  85
GLN A  82
LEU A 130
ALA A 129
LEU A  51
 None
 0.80A 3oapA-2fv2A:
undetectable		 3oapA-2fv2A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		4 / 6 TYR A  58
PHE A 106
PRO A 105
LEU A 103
 None
 1.15A 3tgvB-2fv2A:
undetectable		 3tgvB-2fv2A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_C_BEZC1_0
(HEME-BINDING PROTEIN
HUTZ)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		4 / 5 TYR A  58
PHE A 106
PRO A 105
LEU A 103
 None
 1.14A 3tgvC-2fv2A:
undetectable		 3tgvC-2fv2A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		4 / 6 TYR A  58
PHE A 106
PRO A 105
LEU A 103
 None
 1.20A 3tgvD-2fv2A:
undetectable		 3tgvD-2fv2A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		4 / 8 GLY A 179
ILE A 183
ARG A 189
ILE A 148
 None
 0.74A 4em2A-2fv2A:
undetectable		 4em2A-2fv2A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 LEU A  51
LEU A  50
LEU A  23
ILE A  99
SER A  27
 None
 1.25A 4f4dB-2fv2A:
undetectable		 4f4dB-2fv2A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		4 / 8 ASN A  72
ALA A  68
SER A  71
ARG A 114
 None
 1.08A 4ijiF-2fv2A:
undetectable		 4ijiF-2fv2A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		4 / 7 ASN A  72
ALA A  68
SER A  71
ARG A 114
 None
 1.05A 4ijiH-2fv2A:
undetectable		 4ijiH-2fv2A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ALA A  85
GLN A  82
LEU A 130
ALA A 129
LEU A  51
 None
 0.76A 4nqaH-2fv2A:
undetectable		 4nqaH-2fv2A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 10 LEU A 233
LEU A 237
VAL A 216
LEU A 213
LEU A 204
 None
 1.21A 4po0A-2fv2A:
2.6		 4po0A-2fv2A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		4 / 6 LEU A 103
LEU A  95
PHE A 141
THR A 145
 None
 0.95A 4udaA-2fv2A:
undetectable		 4udaA-2fv2A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ALA A  85
GLN A  82
LEU A 130
ALA A 129
LEU A  51
 None
 0.75A 5uanA-2fv2A:
undetectable		 5uanA-2fv2A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		4 / 8 LEU A  36
VAL A  84
LEU A  13
ILE A  47
 None
 1.00A 5v0vA-2fv2A:
undetectable		 5v0vA-2fv2A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		4 / 4 VAL A 264
LEU A 263
LEU A 221
ASP A 225
 None
 0.74A 5xv7A-2fv2A:
undetectable		 5xv7A-2fv2A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ALA A  85
GLN A  82
LEU A 130
ALA A 129
LEU A  51
 None
 0.89A 5z12C-2fv2A:
undetectable		 5z12C-2fv2A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ALA A  85
GLN A  82
LEU A 130
ALA A 129
LEU A  51
 None
 0.82A 6a5yD-2fv2A:
undetectable		 6a5yD-2fv2A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ALA A  85
GLN A  82
LEU A 130
ALA A 129
LEU A  51
 None
 0.75A 6a5zD-2fv2A:
undetectable		 6a5zD-2fv2A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG
(Homo
sapiens) 		5 / 12 ALA A  85
GLN A  82
LEU A 130
ALA A 129
LEU A  51
 None
 0.76A 6a5zL-2fv2A:
undetectable		 6a5zL-2fv2A:
17.03