SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fvt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 2fvt CONSERVED
HYPOTHETICAL PROTEIN
(Rhodopseudomonas
palustris) 		4 / 8 ILE A  53
LEU A  97
VAL A  95
LEU A  71
 None
 0.90A 2w98B-2fvtA:
undetectable		 2w98B-2fvtA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2fvt CONSERVED
HYPOTHETICAL PROTEIN
(Rhodopseudomonas
palustris) 		4 / 6 VAL A  61
ILE A  16
ALA A 120
LEU A  71
 None
 0.91A 3kk6B-2fvtA:
undetectable		 3kk6B-2fvtA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2fvt CONSERVED
HYPOTHETICAL PROTEIN
(Rhodopseudomonas
palustris) 		4 / 8 SER A  34
PHE A  62
ILE A  68
VAL A  95
 None
 0.93A 4dx7B-2fvtA:
undetectable		 4dx7B-2fvtA:
7.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 2fvt CONSERVED
HYPOTHETICAL PROTEIN
(Rhodopseudomonas
palustris) 		4 / 8 TYR A  19
GLY A  23
GLY A  33
PHE A  24
 None
 0.76A 5albL-2fvtA:
undetectable		 5albL-2fvtA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 2fvt CONSERVED
HYPOTHETICAL PROTEIN
(Rhodopseudomonas
palustris) 		4 / 8 TYR A  19
GLY A  23
GLY A  33
PHE A  24
 None
 0.77A 5alcL-2fvtA:
undetectable		 5alcL-2fvtA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2fvt CONSERVED
HYPOTHETICAL PROTEIN
(Rhodopseudomonas
palustris) 		3 / 3 ASP A  63
ASN A  64
ASP A  40
 None
 0.72A 5vopA-2fvtA:
undetectable		 5vopA-2fvtA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2fvt CONSERVED
HYPOTHETICAL PROTEIN
(Rhodopseudomonas
palustris) 		3 / 3 ASP A  63
ASN A  64
ASP A  40
 None
 0.79A 5vopB-2fvtA:
undetectable		 5vopB-2fvtA:
20.54