SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fxv'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQT_B_ACTB1868_0 (FPRA)	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	3 / 3	ALA A 133 HIS A 134 VAL A 137	None	0.49A	1lqtB-2fxvA: undetectable	1lqtB-2fxvA: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_B_ACTB1425_0 (FPRA)	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	3 / 3	ALA A 133 HIS A 134 VAL A 137	None	0.49A	1lquB-2fxvA: undetectable	1lquB-2fxvA: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJ2_A_SAMA2201_0 (PROTEIN (METHIONINE REPRESSOR))	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	5 / 9	GLU A 155 ARG A 177 ALA A 133 HIS A 134 LEU A 165	None	1.38A	1mj2A-2fxvA: undetectable	1mj2A-2fxvA: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UYQ_A_SAMA1311_0 (HYPOTHETICAL PROTEIN ML2640)	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	4 / 7	ALA A 133 GLY A 135 VAL A  96 LEU A 127	None None None 5GP  A 200 ( 4.8A)	0.73A	2uyqA-2fxvA: 3.9	2uyqA-2fxvA: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADX_B_IMNB3_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	5 / 12	GLY A 149 SER A 146 ALA A 145 VAL A  74 ILE A  54	None	0.93A	3adxB-2fxvA: undetectable	3adxB-2fxvA: 22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LM8_A_VIBA223_1 (THIAMINE PYROPHOSPHOKINASE)	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	4 / 7	LEU A  92 LEU A 114 SER A 146 THR A  52	None	1.00A	3lm8A-2fxvA: 2.8 3lm8C-2fxvA: 2.3	3lm8A-2fxvA: 24.48 3lm8C-2fxvA: 24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HC3_A_DXCA75_0 (PPCA)	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	4 / 7	ILE A  38 LEU A   4 PHE A  25 LYS A  21	None	1.05A	4hc3A-2fxvA: undetectable	4hc3A-2fxvA: 16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M11_A_MXMA606_1 (PROSTAGLANDIN G/H SYNTHASE 2)	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	5 / 12	MET A  35 LEU A  20 LEU A  26 ALA A 176 LEU A 175	None	1.46A	4m11A-2fxvA: undetectable	4m11A-2fxvA: 17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WQ4_A_ACTA403_0 (TRNA N6-ADENOSINE THREONYLCARBAMOYLTRA NSFERASE)	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	3 / 3	VAL A 186 LEU A 181 VAL A  14	None	0.59A	4wq4A-2fxvA: undetectable	4wq4A-2fxvA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOC_B_SAMB401_0 (PAVINE N-METHYLTRANSFERASE)	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	5 / 12	GLY A 130 GLN A 131 VAL A 137 VAL A 166 LEU A 168	5GP  A 200 (-3.4A) None None None None	1.10A	5kocB-2fxvA: undetectable	5kocB-2fxvA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M24_A_9CRA501_1 (RETINOIC ACID RECEPTOR GAMMA)	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	5 / 12	ALA A 176 ILE A 152 SER A 157 GLY A  39 LEU A  34	None	1.11A	5m24A-2fxvA: undetectable	5m24A-2fxvA: 22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UAN_B_REAB503_1 (RETINOIC ACID RECEPTOR BETA)	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	5 / 12	PHE A  42 LEU A  26 ILE A 154 ILE A 152 LEU A   4	None	1.30A	5uanB-2fxvA: undetectable	5uanB-2fxvA: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CK2_C_IPHC101_0 (INSULIN A CHAIN INSULIN B CHAIN)	2fxv	XANTHINE PHOSPHORIBOSYLTRANSF ERASE (Bacillus subtilis)	4 / 4	ILE A 122 LEU A 114 HIS A 119 ALA A 145	None	1.03A	6ck2C-2fxvA: undetectable 6ck2D-2fxvA: undetectable	6ck2C-2fxvA: 9.32 6ck2D-2fxvA: 8.24